2results about How to "Improve dullness" patented technology

This invention discloses an endogenous polypeptide, its preparation method, and its application. The structural formula of the polypeptide is shown in Formula (I): R1-(AA1)m-AA2-AA3-(AA4)n-R2, Formula (I); wherein, m is independently 2 or 3; n is independently 1, 2, or 3; AA1 is independently K, R, or H; AA2 is independently I or W; AA3 is independently I or W; AA4 is independently K, R, or H; R1 is any one of -H, Y, LY, PLY, or LLY; R2 is any one of -OH, L, LL, E, EL, EW, W, EH, or EHL. While retaining its targeted antioxidant and anti-inflammatory functions, the polypeptide has removed the domain with high affinity for heparin, thereby avoiding signal interference and potential biosafety risks that may be caused by full-length PF4, and meeting the safety requirements for cosmetic ingredients.

The present application provides a kind of whitening, improve skin barrier composition and its preparation method and application, it is related to skin care product technical field.The composition raw material includes: plant extract 30-42 parts, Lotus nut extract 13-17 parts, Beauveria extract 12-14 parts, malt oligosaccharide glucoside 1.2-1.6 parts, raspberry ketone glucoside 2-3 parts, oligopeptide 4-6 parts, sucrose laurate 1-2 parts, humectant 2-4 parts, thickening agent 1-1.8 parts, water 280-340 parts.The present application can inhibit tyrosinase activity by the synergistic effect of specific plant extract, Lotus nut extract, Beauveria extract, malt oligosaccharide glucoside, raspberry ketone glucoside, oligopeptide and other raw materials, achieve good whitening effect, and make each active ingredient transdermal absorption, protect skin keratin layer lipid bilayer structure from being destroyed, maintain the water-retention capacity of skin, avoid water loss, thereby play the role of improving skin barrier.