The invention relates to an analgesic antiphlogistic gel and a preparation method thereof. The gel comprises the following raw materials: wild celery, raw rhizoma arisaematis, raw radix aconiti feri, honeylocust, mirabilite, menthyl salicylate, borneol, carbomer 940, ethanol, polyethylene glycol 400 and nautisan. The preparation method comprises the following steps: breaking up the wild celery, the raw radix aconiti feri, the raw rhizoma arisaematis and the honeylocust, soaking and decocting the mixture with water, and performing filtration, concentration, cryoprecipitation and filtration on the decoction; taking glycerine and ethanol and proper amount of purified water, stirring the materials evenly and then adding the mirabilite into the mixture, stirring the mixture evenly to dissolve the mirabilite, adding the carbomer, and standing and swelling the mixture to prepare a gel base material; and adding a liquid medicament, the menthyl salicylate, the borneol, the polyethylene glycol 400 and the nautisan into the gel base material, adjusting the PH to between 5.3 and 6.7, stirring the mixture evenly, and filling the mixture to obtain the analgesic antiphlogistic gel. Because talc powder with the most dosage in auxiliary materials of the base material is removed, the concentration of the effective components carried by the auxiliary materials with the same volume is greatly improved, and the medicament dosage volume is reduced, thus the analgesic antiphlogistic gel not only reduces the preparation cost and the transportation cost, but also is convenient for patients to use.