The invention relates to a preparation method of a Chinese herbal medicine for treating the adult acute pyelonephritis, belonging to the technical field of the Chinese herbal medicine preparation method. Generally, the antibacterial medicine such as penicillin, kanamycin and gentamicin which sometimes have no obvious drug efficacy are used for treating the adult acute pyelonephritis. The technical proposal is that: first, put talc, tuckahoe, agaric, oriental water plantain rhizome, semen plantaginis, barbated skullcup herb, herba polygoni avicularis, fructus kochiae, dyer woad leaf, dyer woad root, weeping forsythia, corydalis, flos hibisci, dandelion, herba patriniae, herba houttuyniae, herba oldenlandiae, pollen typhae, herba agtimoniae, nodus nelumbinis rhizomatis, crinis carbonisatus, herba cirsii, herba ecliptae, raw pagoda-tree pod, raw Chinese rhubarb and raw liquorice root in 1200ml water to steep for thirty minutes; then, use slow fire to boil to 500ml and use gauge to filter the boiled liquor; finally, make into the Chinese herbal medicine for treating the adult acute pyelonephritis. The Chinese herbal medicine has the advantage of an enduring and stable curative effect after an oral dose, thus healing the adult acute pyelonephritis.