314 results about "Officinal" patented technology

The invention relates to selenium-rich health-care rice dumplings. The selenium-rich health-care rice dumplings are prepared from the following raw materials of selenium-rich glutinous rice, rose petals, haw tree parasitism, plum tree parasitism, radix rehmanniae, dendrobium candidum, vegetable oil, pork, mung beans, ground cinnamon and table salt. The selenium-rich glutinous rice is used as a main raw material, so that selenium elements in human bodies are complemented, and collective antioxidation is strengthened; besides, the glutinous rice and the mung beans are soaked in a traditional Chinese medicine extracting solution, and medical components in traditional Chinese medicines are absorbed, so that the selenium-rich health-care rice dumplings have the efficacies of clearing heat, promoting salivation, relieving restlessness, resolving stagnation, reducing blood lipid, promoting digestion and enhancing the immunity of organisms.

The invention discloses a scorpion anti-inflammatory polypeptide as well as a screening method and application thereof, and belongs to the technical field of traditional Chinese medicinal material polypeptides. The scorpion anti-inflammatory polypeptide is one of G4, G5 and G17. The method comprises the following steps: detecting a scorpion buthus martensii polypeptide extract through nanoElute 2 nanoliter liquid phase separation, timsTOFPro2 mass spectrometry and BPS Novor search analysis, screening a scorpion buthus martensii polypeptide, and further synthesizing the screened candidate polypeptide by adopting a solid-phase synthesis method; the effect of the synthesized candidate polypeptide on inhibiting microglial cell inflammation is evaluated through a qPCR method, and then the scorpion buthus martensii anti-inflammatory polypeptide is screened out. The Buthus martensii Karsch anti-inflammatory polypeptides G4, G5 and G17 screened by the method, especially G5, can significantly inhibit microglial cell inflammation and present concentration dependence, a theoretical basis is provided for medicinal development of Buthus martensii Karsch polypeptides, and a potential anti-neuroinflammation mechanism of the Buthus martensii Karsch polypeptides is disclosed.

The invention relates to the technical field of Chinese herbal medicine fermentation, and discloses a mixed strain fermentation method for efficient conversion of non-medicinal parts of traditional Chinese medicine, which comprises the following steps: constructing an intelligent fermentation system comprising a plurality of independent fermentation units, respectively culturing different strains such as aspergillus niger, bacillus subtilis, saccharomyces cerevisiae and the like in each fermentation unit, the online sensor is integrated in the system and used for monitoring key fermentation parameters in real time, and a fermentation model and an optimization algorithm are arranged in the system and can automatically adjust fermentation conditions. An intelligent fermentation system comprising a plurality of independent fermentation units is constructed, precise classification pretreatment and mixing according to a specific ratio are carried out on rhizoma polygonati stems and leaves and gentian stems and leaves, and an intelligent control system is utilized to dynamically regulate and control the fermentation process, so that the synergistic effect of different strains such as aspergillus niger, bacillus subtilis and saccharomyces cerevisiae is fully exerted, and the fermentation efficiency is improved. The dissolution rate and the conversion rate of active ingredients in the non-medicinal part of the traditional Chinese medicine are improved.

The invention relates to the technical field of medicinal packaging container manufacturing, and discloses a processing technology of a double-cavity cartridge bottle, which comprises the following steps: glass tube loading: selecting a glass tube as a raw material, loading the glass tube into a clamping mechanism of forming equipment, fixing the glass tube through a positioning assembly, enabling the axis of the glass tube to coincide with a processing datum line of the equipment, and forming the glass tube; according to the processing technology of the double-cavity cartridge bottle, double-cavity integrated forming is adopted, the strength and the sealing performance of a separation structure of the main body cavity and the bypass cavity are effectively improved, the sealing hidden danger of split splicing is avoided, the leakage and fracture risks are greatly reduced, the technology is matched with the two forming means that a guide pipe is inserted into blow molding and matched with a mold, and medicinal glass raw materials are compatible; the double-cavity cartridge bottle meets the requirements of medical storage for stability and adaptability, meets the storage requirements of various drugs, reduces drug adsorption and chemical reactions, broadens clinical application scenes, and remarkably improves the practical value of the double-cavity cartridge bottle.

The invention provides traditional Chinese medicine small honeyed pill stirring and drying integrated equipment, and belongs to the technical field of traditional Chinese medicine equipment. Comprising a drying mechanism, the drying mechanism comprises a bottom plate, the top of the bottom plate is fixedly connected with a pair of stand columns, bearings are installed on the stand columns through penetrating holes, inner rings of the bearings are fixedly connected with rotating rods, an angle adjusting assembly is arranged between the pair of rotating rods, and a medicine cylinder is installed in the angle adjusting assembly; the medicine barrel comprises a medicine containing barrel body, the medicine containing barrel body is arranged in an inclined mode, and the end, away from the opening, of the medicine containing barrel body is fixedly connected with a connecting barrel communicated with an inner cavity of the medicine containing barrel body. And a stirring drying assembly. By arranging the stirring and drying assembly, the small traditional Chinese medicine honeyed boluses can be piled up and evenly and rapidly dried, by arranging the feeding assembly, the small traditional Chinese medicine honeyed boluses can be rapidly and effectively collected and poured, by arranging the angle adjusting assembly, the feeding assembly can be matched for work, and meanwhile the small traditional Chinese medicine honeyed boluses can be rapidly collected.

The invention relates to the technical field of traditional Chinese medicinal materials, in particular to a method for risk assessment of heavy metals in traditional Chinese medicinal materials. According to the method, heavy metal content data of a traditional Chinese medicine sample is acquired and preprocessed to establish an evaluation model comprising a risk grading module and a comprehensive risk scoring module, and human body exposure is calculated by considering factors such as use frequency, exposure age limit, daily dose and transfer rate of traditional Chinese medicine; and comparing the exposure quantity with a preset health reference value to obtain a single heavy metal risk index, performing weighted calculation by combining the single heavy metal risk index with traditional Chinese medicinal material characteristic parameters (clinical use frequency, average prescription dosage, decoction extraction mode, use crowd range and medicinal part) to obtain a comprehensive risk score, and performing five-level risk grade division and evaluation report generation based on the score. The method breaks through the limitation of traditional binary evaluation, establishes a multi-dimensional risk evaluation system, considers the synergistic effect between heavy metals and the characteristic influence of traditional Chinese medicines, and provides important technical support for guaranteeing the use safety of traditional Chinese medicines and the healthy development of the traditional Chinese medicine industry.

The utility model relates to the technical field of traditional Chinese medicine liquid sub-packaging, and discloses a traditional Chinese medicine liquid sub-packaging processing device which comprises a base and fixing seats, a reserved groove is formed in the top end of the base, a fixing block is arranged at the top end of the reserved groove, and the fixing seats are fixedly connected to the four corners of the top end of the base. A top plate is fixedly connected to the top end of the fixing base, a liquid medicine box is fixedly connected to the top end of the top plate, and a liquid discharging pipe is fixedly connected to the front end of the liquid medicine box. According to the liquid medicine split charging treatment device for the traditional Chinese medicine, parts such as a reserved groove are arranged, a first air cylinder is opened, a fixing table is jacked up through a first telescopic rod, at the moment, a fixing rod can move in a positioning groove, and therefore the height of a containing table can be adjusted, injection can be more accurately conducted during split charging, splashing is not likely to happen, and during later material taking, the containing table can be directly pulled to the outside; and the problems that the platform is inconvenient to lift and the distance between the shunting pipe and the bottle body is relatively long, and the bottle body is easy to splash are solved.

The invention discloses a medicine composition for treating atopic dermatitis, a preparation method and application, the medicine composition comprises inactivated malassezia sphaeroides, and the strain preservation number of the malassezia sphaeroides is ATCC 96807. The cream composition disclosed by the invention is externally applied to local treatment of skin lesions of specific dermatitis, supplements skin symbiotic bacteria, assists in recovering skin barriers of patients, remarkably inhibits growth and proliferation of staphylococcus aureus at the skin lesions of dermatitis and exocrine toxins, remarkably relieves inflammatory response, reduces the thickness of cuticles and reduces inflammatory cell infiltration; the traditional Chinese medicine composition assists the treatment of atopic dermatitis through the effects of the proinflammatory factors and the expression and secretion of the proinflammatory factors, has a remarkable treatment effect on the atopic dermatitis, is quick to take effect, small in toxic and side effects and good in safety, and has a good medicinal prospect.

The embodiment of the invention provides a method and device for constructing a three-dimensional model of traditional Chinese medicine decoction pieces. In a specific embodiment, the method comprises the following steps: taking a traditional Chinese medicine decoction piece as an axis, carrying out multi-angle shooting on the traditional Chinese medicine decoction piece through relative rotation motion of a full-frame camera and the traditional Chinese medicine decoction piece, and obtaining a first image set containing a plurality of different focus images at each shooting angle; performing depth-of-field synthesis on the first image set to obtain a depth-of-field image; separating the background in each depth-of-field image and the main body of the traditional Chinese medicine decoction piece to obtain a second image set containing a plurality of main body images of the traditional Chinese medicine decoction piece; and constructing a three-dimensional model. According to the implementation mode, the quality and form of the traditional Chinese medicine decoction pieces and the characteristics of the medicinal parts are comprehensively and truly displayed, the high-quality three-dimensional model is constructed, the construction efficiency is high, the precision and detail expression of the model are ensured, the high requirement of modern traditional Chinese medicine research for the three-dimensional model is met, and meanwhile the problem of information loss or deformation is avoided.

The invention discloses a single-plate shunting on-line control device for medicinal bottle supports, which relates to the technical field of pharmaceutical equipment and comprises a conveying belt, the conveying belt is arranged on a frame body, a feeding conveying line is arranged at the front section of the conveying direction of the conveying belt, and two shunting conveying lines are arranged at the rear section of the conveying direction of the conveying belt; a first baffle is arranged between the inlet positions of the two flow dividing conveying lines, and a flow dividing area is formed between the first baffle and the outlet of the feeding conveying line. A flow dividing control plate is arranged in the flow dividing area and is in transmission connection with a flow dividing driving mechanism. A flow limiting mechanism is arranged in the middle of the flow dividing conveying line, and a tail end material blocking mechanism is arranged at the tail end of the flow dividing conveying line. According to the device, the medicinal bottle supports can be independently cached and orderly released on a shunting line, and the situation that the medicinal bottle supports are stacked and disordered at the rear end is avoided, so that efficient on-line production with rear-end boxing machine equipment is realized, and the production efficiency is improved.

The grinding equipment comprises a grinding box, the upper surface of the grinding box is fixedly communicated with a feeding port, the outer surface of the grinding box is fixedly connected with two first driving motors, and the output end of each first driving motor is fixedly connected with a first rotating column; and two groups of first bearings are fixedly embedded in the inner wall of the grinding box. According to the device, a first rotating column is driven by a first driving motor, a first crushing roller is driven by the first rotating column, so that veterinary drugs are crushed for the first time by the first crushing roller, a second rotating column is driven by a second driving motor, a second crushing roller is driven by the rotating column, so that the veterinary drugs are crushed for the second time by the second crushing roller, and the grinding effect is improved; according to the veterinary drug grinding device, the problem of low grinding efficiency is solved, the use convenience is improved, the ground veterinary drugs can flow into the collecting box through the two guide plates in the grinding box, and the problem that resources are wasted due to the fact that the veterinary drugs are scattered is avoided.

The invention belongs to the field of pharmaceutical composition preparation, and particularly relates to a traditional Chinese medicine composition for invigorating kidney and strengthening yang and a preparation method thereof, the traditional Chinese medicine composition is composed of the following raw materials by weight: 50 g of epimedium, 50 g of cistanche, 50 g of cordyceps sinensis, 50 g of cynomorium songaricum, and 50 g of eucommia ulmoides. The weight ratio of the herba epimedii to the cistanche to the cordyceps sinensis to the cynomorium songaricum to the eucommia ulmoides is the same and is 1: 1: 1: 1: 1. Therefore, through the raw material combination design that the specific medicinal parts of the raw materials are defined and the weight ratio of the herba epimedii to the herba cistanche to the cordyceps sinensis to the cynomorium songaricum to the eucommia ulmoides is 1: 1, the core effective components of the raw materials are distributed in a balanced proportion, and the effect of synergistically constructing a kidney-tonifying essence-strengthening body-strengthening stable effect system is achieved; therefore, the problems that in the background technology, an existing kidney-tonifying and yang-strengthening traditional Chinese medicine preparation is lack of accuracy in raw material proportioning and fuzzy in medicinal part, so that a preparation effect system is unstable, and the requirements of most people with insufficiency of kidney yang cannot be met are solved.

The utility model belongs to the technical field of medicinal glass bottle conveying, and discloses a medicinal glass bottle conveying device which comprises a conveying belt body, the upper end of the conveying belt body is evenly and fixedly connected with storage fixing assemblies, the storage fixing assemblies comprise placing rings evenly and fixedly connected to the upper end of the conveying belt body, and outer rings are slidably connected to the outer surfaces of the placing rings. Sliding blocks are evenly and fixedly connected to the inner wall of the outer ring, clamping plates are arranged on the inner sides of the sliding blocks, sliding grooves are evenly formed in the outer surface of the containing ring in a penetrating mode, extending grooves are formed in the side walls of the two sides of each sliding groove, and a baffle ring is fixedly connected to the inner wall of the containing ring. According to the medical glass bottle placing device, the bottle edge part of a medical glass bottle can be surrounded to prevent the medical glass bottle from accidentally flying out of the upper portion of the placing ring to be separated, a clamping plate can be pushed and extruded through a baffle ring to open a channel of the placing ring, and therefore the medical glass bottle can be conveniently taken out from the interior of the placing ring; the opening and closing state of the clamping plate can be automatically controlled through the spring.

This invention belongs to the field of traditional Chinese medicine, specifically relating to a topical delay spray and its preparation method. The invention uses the dried epidermis of the Huaxi toad (with the toad venom removed), and extracts it efficiently through a combination of water and alcohol extraction. Male silkworm moth oil can nourish and strengthen the body, tonify the liver and kidneys, and combat fatigue; studies have shown that male silkworm moth oil can effectively treat kidney yang deficiency. This invention combines the synergistic effects of toad skin extract and male silkworm moth oil to prepare a delay spray that can significantly treat premature ejaculation and erectile dysfunction in men. This preparation has the advantages of direct action, sustained release, avoidance of drug contact, and simple operation. This invention further improves the rational utilization system of toad resources, provides a practical solution for the efficient development of toad medicinal resources, and significantly reduces production and clinical application costs.

The application provides the technical field of medical materials and particularly relates to a kind of ultra-thin high-strength nanofiber medicinal casing and a preparation method thereof.The preparation method comprises the following steps: (1) preparing pretreated raw materials; (2) adding a complex enzyme to the pretreated raw materials for enzymolysis, enzymolysis at 35-40 DEG C for 5-8 h, enzyme inactivation, to obtain an enzymolysis product; (3) adding a complex bacteria to the enzymolysis product for anaerobic fermentation, fermentation at 35-40 DEG C for 10-12 h, sterilization, to obtain a fermentation product; (4) rinsing the fermentation product with clean water for 5-8 times, to obtain a casing semi-finished product; (5) mixing nanocellulose, soybean phospholipid and water to prepare a liquid, spraying the liquid on the casing semi-finished product, drying, to obtain an ultra-thin high-strength nanofiber medicinal casing.The casing prepared by the application can be used to wrap traditional Chinese medicine compositions.

The present application relates to the technical field of wound repair, and provides a traditional Chinese medicine composition for promoting wound healing and a preparation method thereof.The traditional Chinese medicine composition comprises a first traditional Chinese medicine composition and a second traditional Chinese medicine composition which are applied to the acute phase and the repair proliferation phase.The former comprises naked flower purple perilla extract, nectarine leaf extract, purple perilla extract, dragon's blood micro powder, spironast extract, centella asiatica volatile oil, rhubarb extract, borneol, mussel mucin, medicinal glycerol and purified water.The latter comprises red algae extract, nectarine leaf extract, radix astragali extract, panax notoginseng total saponins, aloe extract, dendrobium officinale extract, sea buckthorn extract, pinctada martensii purified peptide, snail glycosaminoglycan, medicinal glycerol and purified water.The composition can play the roles of antibiosis, anti-inflammation, hemostasis, analgesia and astringency in the acute phase, and can promote angiogenesis, collagen synthesis and epithelial regeneration in the repair proliferation phase, so that the wound is rapidly repaired and healed.

The application discloses a medicine for warming yang, promoting water excretion and detoxification, and a preparation method and application thereof, and relates to the technical field of traditional Chinese medicines. The medicine for warming yang, promoting water excretion and detoxification provided by the application takes prepared aconite, dried ginger and fried licorice as monarch drugs to stimulate the vital energy of the whole body and supplement yang qi of the heart, spleen and kidney; takes rhubarb and soapberry thorn as minister drugs to clear heat, detoxify and dredge the triple energizer; takes cassia twig and poria as auxiliary drugs to warm yang, promote the circulation of qi, reduce edema and promote water excretion; and takes taizishen as a minister drug to supplement qi, remove dampness and regulate qi movement. The whole prescription can supplement deficiency and eliminate excess, and has the functions of warming yang, detoxification and water excretion. The medicine can treat the root "deficiency of yang qi and invasion of pathogenic factors" of sepsis heart dysfunction, achieve the effect of treating the root and branch at the same time, reduce the inflammation level, cTnT and BNP level of a patient, and achieve the treatment of sepsis heart dysfunction.

The invention discloses an online visual detection device and method for traditional Chinese medicine, and relates to the technical field of traditional Chinese medicine detection.The online visual detection device comprises a base, a visual detection mechanism is arranged on the side edge of the base, the visual detection mechanism comprises a conveying belt, and the conveying belt is fixedly connected to the top of the base and used for conveying traditional Chinese medicine; the visual detection device body is arranged on one side of the conveying belt, the visual camera is installed at the bottom of the visual detection device body, the LED lamp is arranged on one side of the visual camera, the visual camera is used for shooting traditional Chinese medicine, the display screen is fixedly installed on one side of the visual detection device body, and the cleaning mechanism is arranged at the bottom of the conveying belt. According to the cleaning mechanism, the cleaning force of the cleaning assembly is adjusted through cooperation of the extrusion assembly and the elastic telescopic assembly, so that the outer surface of the conveying belt can be well cleaned, and the cleaning assembly is cleaned through cooperation of the first cleaning assembly, the second cleaning assembly and the third cleaning assembly.

Compositions comprising 0.1-50 % delta-9-tetrahydrocannabinol and / or cannabidiol in forms suitable for continuous delivery and use thereof in the treatment of a variety of diseases and pathological disorders are disclosed. In preferred embodiments, the compositions are in a form suitable for delivery via a portable infusion pump or transdermal patch. The disorders to be treated include pain, cancer, seizure disorders, and Parkinson's disease. Depending on the disorder to be treated, the compositions may optionally further comprise additional active agents such as dopaminergic agents.

The utility model relates to the technical field of sustained and controlled release veterinary drug preparation production, and discloses a high-speed mixing granulator for producing sustained and controlled release veterinary drugs, which comprises a case and a container with a cover. The container with the cover can be supported through the machine box, operation can be carried out in a closed state through the container with the cover, feeding is convenient, the movement condition of materials in the shell can be observed conveniently, manufactured spherical particles can be discharged through the discharging device, raw materials can be cut through the cutter device, and the cutting efficiency is improved. The air valve device is used for providing a cooling effect, preventing material adhesion, promoting material flowability and controlling granularity, so that the effects of operation in a closed state, strong shearing force, quick granulation, good granularity, convenience in discharging, capability of enabling materials to generate annular, radial and axial fluidization motion, strong mixing capacity and uniformity are achieved, and the problems that the mixing effect is not good enough, and the mixing efficiency is low are solved. And the movement condition of the materials in the container is inconvenient to observe.

The utility model discloses a kind of to adopt centipede raw material and make traditional Chinese medicine cleaning equipment, the utility model relates to centipede cleaning technical field, including flushing tank, the middle part in flushing tank is fixedly connected with lifting plate, the upper surface of the lifting plate is provided with a plurality of storage device, the storage device includes storage tube, the circumferential side of the storage tube is equipped with a plurality of through holes, the bottom end of the storage tube is through lifting plate and is slidably connected with it, transmission device is arranged in the lifting plate.The cleaning equipment for traditional Chinese medicine using centipede raw material is placed in storage tube by being stored in storage device, flushing tank is provided, through the cooperation of transmission device, stirring device, transmission device drives storage tube to rotate, increase the scouring strength between water, stirring device agitates water flow, further increase flushing efficiency, to realize the cleaning of centipede product.

The utility model relates to the technical field of traditional Chinese medicine mashing processing, in particular to multifunctional traditional Chinese medicine mashing equipment which can effectively improve the working efficiency of traditional Chinese medicine mashing, enable traditional Chinese medicine materials to be mashed more evenly and thoroughly and improve the mashing processing effect of the traditional Chinese medicine materials. Comprising a bottom plate, four supporting legs are fixedly arranged at the bottom end of the bottom plate in an annular array mode, a motor is fixedly installed at the bottom end of the bottom plate, a rotary table is fixedly connected to an output shaft of the motor, a sinking groove is formed in the top end of the bottom plate, and the rotary table is rotatably installed in the sinking groove; the left end and the right end of a spring are fixedly connected with the outer sides of the supporting plates and the inner side of a top block respectively, a plurality of sets of supporting columns are fixedly arranged at the bottom end of an outer ring in an annular array mode, a reciprocating air cylinder is fixedly installed at the top end of a fixing frame, and the output end of the reciprocating air cylinder is fixedly connected with a medicine smashing pestle. The bottom end of the medicine pounding tank contacts with the top end of the turntable.

The invention discloses a pet hair-removing composition containing jerusalem artichoke synanthrin and application of the pet hair-removing composition. Comprising 2-6 parts of jerusalem artichoke synanthrin, 5-10 parts of rhizoma sparganii, 10-20 parts of medicinal jujube, 10-20 parts of medicinal pawpaw and 10-20 parts of euonymus bungeanus. Uniformly mixing chicken oil, olive oil and distilled water; stirring while heating, and homogenizing and emulsifying to obtain a first mixed solution; the rhizoma sparganii, the medicinal jujubes, the medicinal papayas and the euonymus bungeanus are crushed and sieved, mixed powder is obtained, jerusalem artichoke synanthrin, the mixed powder, sodium tripolyphosphate, chicken powder, chicken liver powder, sweet potato starch and the remaining distilled water are added into the first mixed solution, the mixture is stirred to be uniform, and homogenizing emulsification is conducted to obtain the pet hair melting paste. The jerusalem artichoke synanthrin is combined with the traditional Chinese medicines rhizoma sparganii, medicinal jujube, medicinal papaya and euonymus bungeanus for use, so that the intestinal tract movement of pets can be accelerated, the problems of diarrhea, constipation and the like cannot be caused, pet hair is promoted to be discharged out of a body, and the components are safe and can be used for a long time.

The invention discloses external traditional Chinese medicine gel for treating allergic rhinitis and a preparation method of the external traditional Chinese medicine gel, and particularly relates to the technical field of rhinitis treatment. The invention relates to an external traditional Chinese medicine gel for treating allergic rhinitis and a preparation method thereof. The external traditional Chinese medicine gel is prepared from a traditional Chinese medicine extracting solution and a medicinal gel matrix, the traditional Chinese medicine extracting solution is filtrate obtained by soaking tripterygium hypoglaucum leaves and liquorice in table vinegar and filtering. The external traditional Chinese medicine gel for treating allergic rhinitis and the preparation method thereof have the characteristics of quick response, definite curative effect, small side effect and convenience in use.

A base addition salt of a compound represented by formula (I) and a salt crystal form thereof, a preparation method therefor and a use thereof, as well as a pharmaceutical composition containing a therapeutically effective amount of the salt or crystal form and a use thereof in the treatment of ischemic brain injury-related diseases, spinal cord injuries, and neurodegenerative diseases.

This invention belongs to the field of veterinary drug technology, specifically a method for preparing a stress-relieving oral liquid. The specific steps of this method are as follows: weighing the Chinese herbal medicine slices, soaking and pre-treatment, heating and extraction, filtering the extract, vacuum concentration, and preparing the oral liquid. This method uses a low-temperature vacuum concentration process to prepare a Gardenia jasminoides extract after the Chinese herbal medicine extraction, avoiding the destruction of the active ingredients by high temperatures and maximizing the retention of the effective active substances of Coptis chinensis, Scutellaria baicalensis, and Gardenia jasminoides. In the subsequent compounding process, pharmaceutical-grade anhydrous glucose and sodium salicylate are selected as excipients to form a stable and homogeneous system with the compound small molecule peptides and the Gardenia jasminoides extract. This system is free of easily separated, precipitated, or turbid components, effectively tolerating the high temperature and humidity environment of farms, the bumpy rides of long-distance transportation, and the requirements of long-term storage, preventing rapid degradation of the active ingredients of the Chinese herbal medicine, and ensuring the stable efficacy of the oral liquid.

The invention belongs to the field of medical technology and pharmaceutic adjuvant materials, and particularly provides a starch-based soft capsule with high starch proportion (60-72%, w / w) and high forming rate (greater than or equal to 92%), a formula of the starch-based soft capsule, a continuous production process of the starch-based soft capsule and application of the starch-based soft capsule. The starch-based soft capsule overcomes the defects of a traditional soft capsule wall material (mainly animal-derived gelatin), green sustainable materials such as modified starch are used as main solid raw materials and cooperate with a plasticizer formula, reagents such as a disintegrating agent and a release agent are not added, components of the starch-based soft capsule are greatly simplified, and the preparation method is simple and convenient. The problem of compatibility between different components of the soft capsule and filling contents is reduced; and the filling amount of the contents of the soft capsule is increased, and the problem of friability / hardness caused by starch retrogradation is delayed. The invention also provides a novel preparation method of the starch-based soft capsule, and the starch-based soft capsule with high starch proportion, which meets the standard requirements of soft capsules in Chinese pharmacopoeia, and is low in price, high in transparency, high in forming rate (greater than or equal to 92%), strong in packaging property, strong in stability, good in flexibility, green and safe, is obtained. The method has a huge application prospect in the aspects of pharmaceutical preparations, food packaging materials, health-care product packaging materials, cosmetic packaging materials and the like.

The application provides a method for fresh cutting of rhubarb, and belongs to the technical field of traditional Chinese medicinal material processing. After pretreatment of the rhubarb, the rhubarb is decomposed into 2-3 cm thick pieces, dried to have a water content of 52-60%, cut into 5-6 mm thick fresh rhubarb pieces, and dried to obtain medicinal rhubarb tablets. The application can reduce the process flow, shorten the drying time, save energy and improve efficiency, avoid secondary rewetting, maximize the retention of chemical components, stabilize the medicinal material quality, and the fresh-cut medicinal rhubarb tablets are complete and have good appearance after drying.

The application provides application of an acetyl dopamine compound in preparation of a medicine for improving insomnia, and belongs to the technical field of traditional Chinese medicine medicines, and the acetyl dopamine compound is acetyl dopamine dimer A extracted from cicada slough. Experiments prove that the acetyl dopamine dimer A can increase the content of brain-derived neurotrophic factor (BDNF) which plays an important role in the occurrence process of insomnia, reduce dopamine (DA) level, and has obvious effects on DA metabolites homovanillic acid (HVA) and dihydroxyphenyl acetic acid (DOPAC), thereby effectively improving insomnia. Through research on the effect of the acetyl dopamine dimer A on improving insomnia, the application obtains the basis of using the acetyl dopamine dimer A for improving insomnia, provides data support for research and development of the cicada slough as a medicine, and also provides a new medicinal source for improving insomnia.

The composition is prepared from humifuse euphorbia herb, exocarpium benincasae, herba asari, radix platycodonis, radix sophorae flavescentis, radix rehmanniae, leech, lumbricus, radix salviae miltiorrhizae, semen pharbitidis and radix glycyrrhizae, all the raw materials are natural medicinal raw materials, and chemical synthesis anti-hepatic fibrosis components are not contained. Through the synergistic effect of multiple components, the composition inhibits the liver fibrosis process at the molecule, cell and tissue levels, improves the liver structure and function, and can be used for preparing drugs for treating liver fibrosis caused by various causes. The invention has the advantages of naturalness, safety, multiple targets and integral regulation, and is suitable for long-term intervention of chronic liver diseases.