54results about How to "Stable buck" patented technology

The invention relates to a traditional Chinese medicinal composition for treating hypertension, which is prepared from ginseng, Chinese angelica root, epimeddium, wolferry fruit, root of red rooted saliva, tetrandra root, selfheal, bark of peony root, buthus martensi karsch, wild jujuba seeds and haw. The invention also provides the process for preparing the medicament.

The invention relates to a levamlodipine besylate tablet, a preparation process thereof and a control method for relevant materials. Each 1000 levamlodipine besylate tablets provided by the invention comprise the following compositions: 2.5g of levamlodipine besylate (measured in besylate), 30 to 50g of lactose (as a filler), 20 to 40g of beta-cyclodextrin (as an inclusion agent), 25 to 45g of microcrystalline cellulose (as a disintegrating agent), 5 to 15g of cross-linked polyvinylpyrrolidone (as a disintegrating agent), 1 to 2g of magnesium stearate (as lubricant), and 50 to 80g of 2.5% HPMC (hydroxypropyl methylcellulose) and 50% ethanol (as an adhesive). The levamlodipine besylate tablet provided by the invention has the advantages of making multi-item improvements on the properties of the levamlodipine besylate, increasing the solubility and apparent dissolution rate of the tablet, improving the stability of the tablet, reducing the excitability of the tablet, significantly reducing the limit of the relevant material, and having better clinical treatment effect, so that the blood pressure lowering of the patient with hypertension is more stable.

The invention relates to a pure Chinese medicinal composition, in particular to a Chinese medicinal preparation for treating high blood pressure. The Chinese medicinal preparation comprises the following raw medicaments in part by weight: 20 to 1,500 parts of Spanish needle herb, 30 to 1,200 parts of gambir plant, 30 to 1,200 parts of mountain green tea, 1 to 50 parts of eucommia bark, 10 to 130 parts of root of red rooted salvia, 10 to 150 parts of achyranthes root, 1 to 50 parts of cassia seed, 10 to 150 parts of kudzuvine root, 10 to 1,500 parts of Guangzhou hawthorn, 10 to 200 parts of oyster, 10 to 120 parts of magnetite, 10 to 150 parts of lotus leaf, 10 to 1,200 parts of keel and 10 to 1,200 parts of red ochre. The Chinese medicinal preparation can quickly and stably reduce blood pressure, change over the pathogenesis of the high blood pressure and solve the difficult problem of lifelong medicament administration of high blood pressure patients.

The health product with functions of reducing blood fat and lowering blood pressure is prepared with refined ginseng oil, red pine seed oil and purple perilla oil in the weight ratio of 1 to 3-7 to 12-16, and through mixing, stirring for 20-40 min and packing. The health product of natural materials has simple production process, low cost and no side effect.

A Chinese medicine for treating hypertension is prepared from 12-15 Chinese-medicinal materials including Dragon's bone, oyster shell, sea-ear shell, yam, etc.

Disclosed is a medicinal pillow for treating hypertension, wherein the content of the pillowcase comprises the following pharmaceutical constituents: allume 45-55 parts, kudzuvine root 3-5 parts, chrysanthemum flower 2-4 parts, apocynum venetum linn 2-4 parts, cassia seed 2-4 parts.

The invention provides a traditional Chinese herbal medicine composition with a hypotensive effect and application thereof, and belongs to the technical field of traditional Chinese medicine. The traditional Chinese herbal medicine composition with the hypotensive effect comprises the following ingredients in parts by weight: 20 parts of folium cortex eucommiae, 0.05 to 2 parts of gastrodia elata and 1 to 10 parts of chrysanthemum or wild chrysanthemum. The traditional Chinese herbal medicine composition reinforces the hypotensive effect of the folium cortex eucommiae through the compatibility effect of the gastrodia elata and the chrysanthemum (wild) chrysanthemum. The traditional Chinese herbal medicine composition with the hypotensive effect has the advantages that the composition is simple, the quality can be easily controlled, and the safety is good. The traditional Chinese herbal medicine composition can be used for developing the traditional Chinese medicine, can also be used for developing health care food, and has wide application prospects.

The invention is concerned with the hypertensive therapy and it contents: radix salviae miltiorrhizae, bark of boxthorn root, seaweed, Tangle, pagoda tree flower, and Dilute Siegesbeckiae grass 30g of each, Chuanxiong (rhizome) 20g, cortex moutan, Parasitic, radix cirsii jeponici, madder and bidentate achyranthes 15g of each, core of Hindu lotus seed, lotus leaf 10g of each. All of the raw materials can dip in clear water for 30 minutes, concentrate two portions to only one by decocting twice. It can take twice a day with no sediment. The blood pressure declines stably in 7-10days after taking the medicine and stabilizing within the normal range after 30 days.

The invention provides an externally-applied TCM (traditional Chinese medicine) patch for treating hypertension, and the effective ingredient of the patch is prepared from the following bulk pharmaceutical chemicals in parts by weight: 20-60 parts of magnetite, 10-30 parts of radix achyranthis bidentatae, 15-50 parts of rhizoma ligustici wallichii, 10-30 parts of evodia rutaecarpa, and 2-10 parts of borneol. The externally-applied TCM patch disclosed by the invention is prepared by taking Chinese medicinal herbs as main ingredients through meticulously decocting main ingredients by using the traditional plaster preparation process; and through attaching the patch to a symptomatic acupuncture point, the self disease resistance of the human body is excited, thereby achieving the purpose of balancing the Yin and Yang of the human body and removing sputum and stasis toxins in the body, so that effects of blood reconciling, unimpeded channels and collaterals, and physical and mental health are achieved. The externally-applied TCM patch disclosed by the invention is easy to use and clear in curative effect, and has no side effect, and therefore, the externally-applied TCM patch is worthy of promoting.

The invention discloses a propranolol-eugenol type basil oil nano-emulsion medicament, which consists of the following raw materials in percentage by mass: 1-10 percent of propranolol, 10-30 percent of surfactant, 0-25 percent of cosurfactant, 1-15 percent of eugenol type basil oil and the balance of distilled water, wherein the mass percentage sum of the raw materials is 100 percent. A nano-emulsion has the characteristics of small emulsion drop particles, uniform distribution, low viscosity and high flowability. In a nano-emulsion dosage form, propranolol serving as a water-soluble medicament is organically combined with fat-soluble eugenol type basil oil, so that the dissolving and permeation capabilities of eugenol type basil oil are increased, and the stability and medicament effect of propranolol are enhanced. After the propranolol and the eugenol type basil oil are prepared into a nano-emulsion dosage form, the advantages of the propranolol and the eugenol type basil oil are combined, the hypertension resisting effect is enhanced remarkably, the half-life period of a medicament is prolonged, and the administration times are reduced.

The invention discloses an application of Elabela polypeptide in preparation of a medicine or functional food for preventing and / or treating diseases related to chronic kidney injury and the medicinethereof. The diseases related to chronic kidney injury comprise (i) chronic renal insufficiency caused by hypertension; or ii) chronic renal insufficiency with hypertension. The Elabela polypeptide isstable in blood pressure reduction, can effectively relieve glomerular pathological injury of SD rats induced by deoxycorticosterone, reduce discharge of urine microalbumin, relieve development of renal fibrosis and reduce expression of inflammatory factors in kidney tissues, and has a remarkable effect on treatment of chronic kidney injury. Meanwhile, the Elabela polypeptide is an endogenous hormone synthesized by a human body and is expressed in kidney tissue, so that the toxic and side effects are smaller than those of the existing medicine for treating chronic kidney injury.

A Chinese medicine for treating hypertensionand preventing cerebral arteriosclerosis, encaphalorrhagia, cerebral infarction, etc is prepared from 11 Chinese-medicinal materials including seabuckthorn fruit, dendrobium, ophiopogon root, chrysanthemum flower, etc.

The invention discloses a traditional Chinese medicinal sole center patch for treating hypertension. The traditional Chinese medicinal sole center patch for treating hypertension is prepared from the following components in parts by weight: 20-50 parts of uncaria, 10-30 parts of caster bean, 20-50 parts of hawthorn, 20-50 parts of selfheal, 20-50 parts of fructus evodiae, 20-50 parts of monkshood, 10-30 parts of pseudo-ginseng, 20-50 parts of caulis spatholobi, 20-50 parts of semen raphani, 10-30 parts of fresh ginger, 1-10 parts of borneol, 20-50 parts of ginseng, 5-20 parts of antelope horn powder, 20-50 parts of safflower, 20-50 parts of Chinese angelica and 20-50 parts of salviae miltiorrhizae. The invention also discloses a preparation method of the traditional Chinese medicinal sole center patch for treating hypertension. The traditional Chinese medicinal sole center patch for treating hypertension is reasonable in formula, smooth and steady in blood pressure lowering, obvious in curative effect and low in recurrence rate; no chemical is added, and no toxic or side effect is produced after the traditional Chinese medicinal sole center patch for treating hypertension is used for a long time; meanwhile, the traditional Chinese medicinal sole center patch for treating hypertension is simple and easy to use, and medication compliance of a hypertensive patient is effectively improved.

The present invention relates to one kind of medicine composition for treating hypertension, and features that the medicine composition is prepared with medicine materials including gastrodia tuber, sealwort, fried eucommia bark, cassia obtusifolia, madder, white puncture vine, oriental water plantain, water melon seed and atenolol in certain weight proportion. Compared with singly Western medicine, the medicine composition of the present invention has the advantages of stable blood pressure lowering, effective lowering of the diastolic pressure and effect of lowering systolic pressure singly.

The hypertension treating capsule as one kind of orally taken Chinese medicine preparation has the features of stable blood pressure lowering, less recurrence and effective prevention of hypertension complication. It is prepared with cassia seed, ginseng, figwort, tortoise plastron, schisandra and other nine kinds of Chinese medicinal materials. The present invention has high curative rate of hypertension.

The invention belongs to the technical field of drugs, and relates to a felodipine sustained-release tablet. The felodipine sustained-release tablet is prepared from the following components in weightby percent: 1 to 5% of felodipine, 5 to 20% of hydroxypropyl methylcellulose, 1 to 10% of hydroxypropyl cellulose, 10 to 40% of hydrophobic fillers, 40 to 70% of hydrophilic fillers, and 5 to 20% ofother pharmaceutical excipients. The felodipine sustained-release tablet can make release degree of the drugs more uniform at a constant speed.

The invention belongs to the field of medicine preparations, which relates to a medicine composition containing the active components of levorotatory amlodipine / amlodipine and losartan. Concretely, the medicine composition is an osmotic pump preparation. The osmotic pump preparation contains main medicines, high molecular substances, a surfactant, an osmotic pressure promoter, an osmosis promotion polymer and auxiliary materials of other conventional preparation tablets and a coating. The medicine composition represents an obvious advantage in the indexes of the pressure relief, the sugar tolerance, the urine content of urine trace albumin, blood leucocyte after stress and the like.

The invention relates to the technical field of medicine, in particular to a herba violae extract with an antihypertensive effect. The extract is prepared through the method comprising the following steps: smashing herba violae, adding distilled water for microwave extraction, standing to get supernatant liquid, maintaining residues, concentrating the supernatant liquid under a rotary evaporator to form a paste with the water content of 8%, carrying out vacuum drying on the paste, smashing the paste into powder A, adding ethyl alcohol into the residues for carrying out reflux extraction for 1 hour, concentrating an extracting solution under the rotary evaporator to form paste with the water content of 8%, carrying out vacuum drying on the paste, smashing the paste into powder B, and mixing the powder A with the powder B to form the herba violae extract with the antihypertensive effect. The herba violae extract with the antihypertensive effect disclosed by the invention has the effects of strengthening blood capillary resistance, expanding coronary artery and increasing the blood flow volume of the coronary artery, and the blood pressure is reduced stably without toxic or side effect.

The present invention relates to one kind of compound hypotensor preparation, and belongs to the field of hypertension treating medicines. The compound hypotensor preparation contains the active components comprising metoprolol 25-100 weight portions, captopril 25-100 weight portions and hydrochlorothiazide 12.5-25 weight portions. The compound hypotensor preparation has high curative effect, less side effect high performance / cost ratio, taking convenience and raised patient's compliance. It is used mainly in treating hypertension, and may be also used in treating angina pectoris, heart failure and diabetes.

The invention discloses a benazepril hydrochloride-hyacinth oil nanoemulsion antihypertensive drug. Raw materials for the drug comprise, by mass percentage, 1% to 18% of benazepril hydrochloride, 15% to 40% of surfactant, 0 to 20% of cosurfactant and 1% to 20% hyacinth oil, with the balance being distilled water, wherein the sum of the mass percentage of the raw materials is 100%. Nanoemulsion provided in the invention has small and uniformly-distributed emulsion droplet particles, low viscosity and good fluidity. In the dosage form of nanoemulsion, the water-soluble drug benazepril hydrochloride and fat-soluble hyacinth oil are organically combined together, which improves the solubility and permeability of hyacinth oil and the stability and efficacy of benazepril hydrochloride. When the dosage form of nanoemulsion is prepared from benazepril hydrochloride and hyacinth oil, the advantages of both benazepril hydrochloride and hyacinth oil are combined; therefore, an antihypertensive effect of the drug provided in the invention is obviously improved, the half-life of the drug is prolonged, and administration frequency is reduced.

The invention provides a traditional Chinese medicine composition for treating hypertension. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10-20 parts of radix astragali, 8-15 parts of radix salviae miltiorrhizae, 6-15 parts of radix angelicae sinensis, 1-8 parts of radix notoginseng, 5-16 parts of ramulus uncariae cum uncis, 5-20 parts of flos chrysanthemi, 2-18 parts of flos carthami and 4-16 parts of concha margaritifera usta. The invention also provides a preparation method of the traditional Chinese medicine composition for treating hypertension. The traditional Chinese medicine composition has a good treatment effect on patients with the hypertension, is capable of stably reducing hypertension, is low in recurrence rate, and is also capable of effectively preventing complications caused by the hypertension and achieving the curative effect of treating both symptoms and root causes.

The invention discloses a traditional Chinese medicine composition for treating hypertension. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 13 to 17 parts of radix rehmanniae recen, 9 to 11 parts of gastrodia elata, 8 to 12 parts of semen raphani, 13 to 17 parts of paenoiae alba, 5 to 7 parts of chrysanthemum, 13 to 17 parts of semen cassia, 14 to 16 parts of medicinal cyathula root, 2 to 4 parts of colla corii asini, and 13 to 17 parts of fructus lycii. The traditional Chinese medicine composition for treating hypertension has a good effect on treating a patient suffering from hypertension, and can stably lower down the hypertension and recovers blood fat and cholesterol of the patient to be normal, and therefore, the independence on Western medicines can be reduced, and even the Western medicines can be stopped from being taken.

The invention discloses a traditional Chinese medicine for treating hypertension. The traditional Chinese medicine is prepared from, by weight, 5-15 parts of fructus podophylli, 6-12 parts of folium ilicis hainanensis, 4-10 parts of toasted seeds of feather cockscomb, 5-12 parts of common gendarussa herb, 3-8 parts of phlogopitum, 10-20 parts of male fern rhizome, 5-15 parts of rhizoma dioscoreae septemlobae, 4-15 parts of manchurian lilac bark, 2-8 parts of Chinese knotweed herb, 3-14 parts of jasminum grandiflorum and 10-20 parts of scutellaria baicalensis. The traditional Chinese medicine can rapidly and stably reduce blood pressure, effectively eliminate bad symptoms such as dizziness, palpitation, choking sensation in chest, shortness of breath, flustering, lacking in strength, insomnia and amnesia caused by hypertension, rapidly relieve the body illness conditions of patients, effectively restore functional injury of heart, brain and kidney caused by hypertension and enable the blood system to recover the self regulation functions from pathogenesis, and has the advantages of being effective rapidly, stably reducing blood pressure, being unique in treatment effect and having no adverse reaction.

The invention discloses an intelligent circumfluence pressure regulator, which includes a front valve body and a rear valve body. The front valve body is provided with a center axle hole, the center axle hole is provided with a main valve shaft, a diversion end cover, a wear-resisting sealing valve seat and a diversion valve head, the diversion valve head is fixed to one end of the main valve shaft, the other end of the main valve shaft is connected with a closed-loop linear actuator, and the wear-resisting sealing valve seat is matched with the diversion valve head; the rear valve body is provided with an internal cavity and an external cavity which are mutually isolated, the closed-loop linear actuator is installed and fixed into the internal cavity, and the external cavity is a gas outflow channel; and the front valve body and the rear valve body are provided with pressure sensors correspondingly, the front valve body is provided with an inlet pressure sensor, and the rear valve body is provided with a pressure transmitter and a display shell. The intelligent circumfluence pressure regulator can easily realize six operation modes comprising an automatic pressure regulating mode,an automatic current limiting mode, an automatic low flow mode, a multi-period pressure reservation mode, a multi-period current limiting reservation mode and a gas total accumulation mode correspondingly, and meanwhile, the functions such as gas metering are achieved.

The invention provides a preparation method of a deuterium-depleted water beverage for preventing and treating 'four highs'. The method comprises the following steps: 1) preparing lentinan; 2) preparing soy protein peptide hydrolyzate; 3) placing hawthorn, straight ladybell root, platycodon, mulberry leaf, pueraria, purslane, medlar, corn stigma, astragalus and chicory in deuterium-depleted water,boiling for 2-3 hours to obtain a Chinese herbal extract; 4) mixing the lentinan and the soy protein peptide hydrolyzate with the Chinese herbal extract obtained in the step 3) and conducting sterilization to obtain the deuterium-depleted water beverage for preventing and treating 'four highs'. Compared with the prior art, the deuterium-depleted water is adopted as one of the main raw materials,the preparation process of the lentinan and the soy protein peptide is controlled, the dosage of the hawthorn, the straight ladybell root, the platycodon, the mulberry leaf, the pueraria, the purslane, the medlar, the corn stigma, the astragalus and the chicory is designed, and the effects of lowering the 'four highs' of high blood fat, high blood sugar level, high blood pressure and high uric acid can be achieved the synergistic effect of the various raw materials.

A Chinese medicine for treating hypertension is prepared from 12-15 Chinese-medicinal materials including Dragon's bone, oyster shell, sea-ear shell, yam, etc.

The invention provides a traditional Chinese medicine composition for treating hypertension through external application and application as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following Chinese herbal medicines in parts by weight: 5-80 parts of lignum dalbergiae odoriferae, 5-50 parts of ligusticum wallichii, 1-40 parts of mint, 5-80 parts of peach kernel, 5-60 parts of almond, 5-80 parts of selfheal, 3-60 parts of leech, 5-50 parts of gardenia and 3-30 parts of white pepper. The traditional Chinese medicine composition is remarkable in effect, low in cost and free of toxic and side effects.

The invention relates to a traditional Chinese medicine combination treating hypertension and application thereof. The combination is prepared from, by weight, 23-35 parts of tea tree roots, 21-30 parts of plantain herb, 8-14 parts of fried caltrop, 17-25 parts of lotus leaves, 8-14 parts of cockscomb, 8-14 parts of lantern plant calyx, 8-14 parts of morinda officinalis, 6-12 parts of platycladi seeds, 6-12 parts of birthwort and 6-12 parts of Szechwan chinaberry fruits. Effective components of traditional Chinese medicine materials are extracted through a water extraction method and are prepared into oral liquid and other oral preparations, and the traditional Chinese medicine combination has the advantages of being little in use amount, stable in blood pressure reduction, little in irritation, free of toxic and side effects, wide in raw material resource, low in price and the like.