Compound blood pressure reducing preparation
A preparation and compound technology, applied in the field of medication for hypertension, can solve the problems of increased dosage, easy occurrence of adverse reactions, etc., and achieve the effects of improving blood pressure lowering effect, facilitating hypertensive patients, and reducing morbidity and mortality.
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Embodiment 1
[0032] Compound antihypertensive capsule batching of the present invention consists of:
[0033] Metoprolol 25g
[0034] Captopril 50g
[0035] Hydrochlorothiazide 12.5g
[0036] Starch 80g
[0037] Lactose 50g
[0038] Hypromellose 20g
[0041] A total of 1000 capsules are made
[0042] The preparation method is as follows:
[0043] ①Raw material processing: Weigh the raw materials of metoprolol, captopril and hydrochlorothiazide, mix them evenly, pulverize them, pass through a 100-mesh sieve, put them in the container for later use.
[0044] ② Processing of auxiliary materials: pass starch and talcum powder through a 160-mesh sieve, and magnesium stearate through a 80-mesh sieve, and set aside.
[0045] ③ Weighing: Weigh the starch, lactose, and hydroxypropyl cellulose according to the prescription amount, and plac...
Embodiment 2
[0054] Compound antihypertensive tablet batching of the present invention consists of:
[0055] Metoprolol 25g
[0056]Captopril 50g
[0057] Hydrochlorothiazide 12.5g
[0058] Microcrystalline Cellulose 40g
[0059] Lactose 50g
[0060] Hypromellose 20g
[0062] A total of 1000 pieces were made
[0063] The preparation method is as follows:
[0064] ①Auxiliary material processing: pass the magnesium stearate through an 80-mesh sieve, and set aside.
[0065] ②Raw material processing: Weigh the raw materials of metoprolol, captopril, hydrochlorothiazide and microcrystalline cellulose, lactose, and hyprolose according to the prescription, mix them evenly, pulverize them, pass through a 100-mesh sieve, and place them in a container for later use .
[0066] ③Preparation of granules: Put the above-mentioned raw and auxiliary materials in a mixer, add appropriate amount ...
Embodiment 3
[0074] Compound antihypertensive sustained-release tablet of the present invention consists of ingredients:
[0075] Metoprolol 50g
[0076] Captopril 100g
[0077] Hydrochlorothiazide 25g
[0078] Starch 80g
[0079] Lactose 80g
[0080] Hypromellose 20g
[0081] Ethyl cellulose 10g
[0083] A total of 1000 pieces were made
[0084] The preparation method is as follows:
[0085] ①Auxiliary material processing: pass the starch through a 160-mesh sieve, and pass the magnesium stearate through a 80-mesh sieve, and set aside.
[0086] ②Raw material processing: Weigh the raw materials of metoprolol, captopril and hydrochlorothiazide, starch and lactose according to the prescription, mix them evenly, pulverize them, pass through a 100-mesh sieve, put them in a container, and set aside.
[0087] ③ Weigh the prescribed amount of ethyl cellulose and hypromellose, swell with 80% et...
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