35 results about "Hypertensive heart disease" patented technology

The invention discloses a Chinese medicinal herb composition for treating hypertensive heart disease and a preparation method thereof, wherein the Chinese medicinal herb composition mainly comprises American ginseng, astragalus mongholicus, stigma croci, poria cocos, radices trichosanthis, semen boitae, dalbergia wood, radix ophiopogonis, radix paeoniae alba, selfheal, natural borneol (d-borneol) and uncaria; the Chinese medicinal herb composition has the effects of benefiting qi and nourishing blood, stopping cardiac pain, regulating qi, eliminating the sense of suppression in the chest and calming the nerves; besides, the Chinese medicinal herb composition has good relief effect on palpitation, choking sensation in chest and stenocardia caused by the hypertensive heart disease, and also has obvious treatment effect on the hypertensive heart disease. As a result, the Chinese medicinal herb composition is an ideal medicine for treating the hypertensive heart disease, and is safe and completely free of side-effect.

The invention belongs to the field of medicines and particularly relates to a capsule of a traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases. The capsule is prepared from the following components by weight: tatarinow sweetflag rhizome, salvia miltiorrhiza bunge, platycladi seed, polygala tenuifolia, liriope, poria with hostwood, pollen typhae, tortoise shell, dragon bones, purslane, rehmanniae praeparatum, antler, and acanthopanax, which are respectively 1.5 parts; szechuan lovage rhizome, coptis chinensis, amur corktree bark, pinellia ternate, corydalis tuber, rhizoma curcumae longae, angelica sinensis, astragalus mongholicus, spina date seed, twotooth achyranthes root, white paeony root, earthworm, ginseng, teasel root, mulberry leaf, rhizoma polygonati, rehmanniae vaporata, zedoary, semen cassiae, tuber fleeceflower stem, leonurus, herba epimedii, rhizoma drynariae and bupleurum, which are respectively 1.3 parts; elecampane, rhizoma atractylodis, fried bighead atractylodes rhizome, bitter orange, polygonum cuspidatum, dried orange peel, hairyvein agrimony and purple perilla, which are respectively 1 part; and capillary artemisia and pearl, which are respectively 0.5 part. The preparation has the advantages of wide and rapid curative effect and high cure rate, is a pure traditional Chinese medicine preparation without any toxicor side effect and is suitable for arrhythmia, auricular fibrillation, ventricular conduction block, coronary heart disease, coronary atherosclerotic heart disease (angina and myocardial infarction),mitral valve stenosis, mitral valve insufficiency and hypertensive heart disease complications.

The invention belongs to the field of a medical technology and discloses a traditional Chinese medicine composition for treating hyperlipidemia. The traditional Chinese medicine composition is prepared from the following Chinese herbal medicines, by weight, 8-35 parts of radix astragali, 4-20 parts of fleece-flower root, 7-26 parts of rhizoma alismatis, 5-34 parts of poria cocos, 12-41 parts of bitter orange, 10-33 parts of pinellia ternate, 3-18 parts of flos farfarae, 6-20 parts of cassia seed, 1-11 parts of cornu bubali, 5-14 parts of radix paeoniae rubra, 3-13 parts of balloonflower root, 7-19 parts of wrinkled giant hyssop, 6-21 parts of desmodium, 5-19 parts of potentilla discolor, 12-23 parts of radix ophiopogonis and 3-22 parts of polygala root. The traditional Chinese medicine composition has a good curative effect after clinical application, has little side effect and is suitable for various diseases such as atherosclerosis of coronary artery, myocardial infarction, hypertensive heart disease, cardiomyopathy, cerebrovascular disease, cerebral arteriosclerosis, lacunar infarction, cerebral thrombus, cerebral hemorrhage sequelae, cirrhosis, renal arteriosclerosis, diabetes and the like which are caused by hyperlipidemia. By the use of the traditional Chinese medicine composition, blood fat can be reduced to normal level within a short period of time. The traditional Chinese medicine composition has supportive therapeutic efficacy of treating the above diseases. Cure rate of the traditional Chinese medicine composition for treating hyperlipidemia reaches more than 70%, and total effective rate reaches more than 98%.

The invention discloses a Chinese medicinal composition for treatment of chronic heart failure and a preparation method thereof. The Chinese medicinal composition is composed of the following components by weight: 140-160 parts of ginseng, 180-200 parts of Salvia Miltiorrhiza, 180-200 parts of Allium macrostemon, 240-260 parts of semen lepidii, 240-260 parts of Poria cocos, 180-200 parts of curcuma zedoary, and 180-200 parts of peach kernel. The preparation method includes: weighing the components and adding water for decoction, concentrating the decoction to obtain a concentrated solution; adding ethanol into the concentrated solution to conduct extraction, recovering ethanol from the supernatant recycling ethanol till no alcohol flavor; adding simple syrup into sinking liquid, adjusting the pH value, and performing filtering, thus obtaining the Chinese medicinal composition. The Chinese medicinal composition provided by the invention can significantly improve the chronic heart failure model of rats, has certain treatment effect on chronic heart failure, and can be used for treatment of cardiac insufficiency and chronic cardiac failure caused by coronary heart disease, hypertensive heart disease, rheumatic heart disease, cor pulmonale and cardiomyopathy, etc.

The invention belongs to the technical field of traditional Chinese medicines, in particular relates to new application of a natural plant medicine material and / or extract thereof in medicines for treatment of heart disease, and relates to application of murraya tetramera huang and / or extract thereof in the medicines for treatment of heart disease. The murraya tetramera huang is obtained by crushing any one of leaf, branch, root, flower and fruit of murraya tetramera huang or combination thereof to use as a medicine; the extract is obtained by crushing the murraya tetramera huang, leaching at room temperature, heating for reflux and supercritically extracting, and a solvent used for extraction is a liquid prepared by mutually mixing water and ethanol in any proportion for dissolving, or a liquid prepared by mutually mixing acetone, ether, petroleum ether, chloroform and ethyl acetate in any proportion for dissolving, or liquid CO2. The murraya tetramera huang and / or extract thereof are / is mainly used for comprehensive treatment of coronary heart disease, rheumatic heart disease, hypertensive heart disease, pulmonary heart disease, myocardiopathy, cardiac tumor and vasculopathy. Animal experiments and clinical experiments show that the prepared medicinal preparation has no obvious adverse reactions and toxic and side effects, and is a natural plant medicine capable of providing safe and efficient treatment of heart disease for patients.

A drug for preventing or treating heart diseases which comprises an expression vector containing CD9 gene as the active ingredient. In the present invention, the term “heart diseases” means diseases causative of heart failure, ischemic heart diseases, cardiomyopathy, hypertensive heart diseases, valvular disease, congenital heart diseases, mayocarditis, arrhythmia and diseases associated with cardiac hypertrophy and / or tachycardia. In the present invention, the expression vector is a viral vector or a non-viral vector. A method for preventing or treating heart diseases which comprises expressing the CD9 gene in the heart. In the present invention, the prevention or the treatment is carried out by a gene therapy of transferring the CD9 gene. In the gene therapy, use is made of a drug comprising an expression vector containing the CD9 gene as the active ingredient.

The present invention relates to a pharmaceutical use of rebamipide used in the prevention or treatment of hyperlipidemia and diseases related thereto, in particular to hyperlipidemia containing rebamipide as an active ingredient and its combination with Compositions for the prevention or treatment of related diseases. The rebamipide compound according to the present invention inhibits the production of TNF-a, IL-6 and IL-1b as hyperlipidemia-induced inflammatory cytokines secreted in macrophages; and inhibits the formation of atherosclerotic plaque ( Artherosclerotic plaque) precursor cell foam cell (Foam cell) generation; reduce blood total-cholesterol, LDL-cholesterol and neutral fat value to improve blood lipids; improve fatty liver; inhibit B cell activity; make accelerated arteries The expression of Th17, which is responsible for the formation of sclerotic plaques, is reduced, while the expression of Treg cells, which can control the inflammatory response, is increased. Accordingly, the rebamipide compound can be advantageously used as a pharmaceutical composition capable of preventing or treating hyperlipidemia and associated arteriosclerosis, heart failure, and hypertensive heart disease through various mechanisms as described above . In addition, there is no toxicity and side effects as a drug, so it can be used safely even if taken for a long time, and it has a stable effect in the body.

The invention belongs to the technical field of medicines and specifically relates to a traditional Chinese pharmaceutical composition for treating hypertension. The traditional Chinese pharmaceutical composition is characterized by being prepared from the following main raw materials in weight proportion: 20 to 60 parts of folium evodiae leptae, 10 to 22 parts of gambir plant, 4 to 27 parts ofpericarpium zanthoxyli, 4 to 27 parts of concha haliotidis, 5 to 30 parts of raw fructus crataegi, 3 to 30 parts of cortex eucommiae, 2 to 30 parts of spica prunellae, 4 to 30 parts of fructus lycii, 2 to 18 parts of rhizoma coptidis and 5 to 15 parts of herba taxilli. The traditional Chinese pharmaceutical composition for treating the hypertension disclosed by the invention has obvious effect on treating hypertensive heart disease. Clinical experiments show that an effective rate is 95%, and a cure rate is 70%.

The invention relates to a medicament for treating cardiovascular diseases and a preparation method thereof. The medicament is prepared from red-rooted salvia root, peach kernel, rhizoma alismatis, radix angelicae pubescentis, common burreed rhizome, yam, bamboo shavings and mistletoe, has remarkable effects to hypertensive heart disease, mild heart failure, myocarditis, coronary heart disease, angina pectoris, myocardial infarction and other cardiovascular diseases, and can be used for improving immunity and resisting age. The medicament is formed according to the traditional Chinese medicine theory and modern research results, has mild drug property, does not have toxic or side effect or adverse reaction, and has the advantages of simple production process, low price, convenience in use, wide treatment range, quick response, durable action, no drug resistance and relapse prevention. Years of clinical application prove that the effective rate of the medicament is over 90 percent.

The invention relates to wheat bran puffed food and a manufacturing method thereof. The wheat bran puffed food comprises the following raw materials: wheat bran, stevioside or sugar, psyllium husk powder, salt and baking soda. The manufacturing method comprises the following steps : crushing the wheat bran, screening with a 30-mesh sieve, uniformly mixing the wheat bran wiht the rest raw materials, adding water, uniformly agitating, feeding into a material box of a double-screw extruder, feeding into a drying box to dry after extrusion and puffing treatment and obtaining the wheat bran puffed food. The wheat bran puffed food has the advantages that the wheat bran puffed food adopts the wheat bran and the psyllium husk powder as the raw materials, contains rich dietary fiber, group-B vitamins and other nutrient elements, is high-dietary fiber food, meets the demand quantity of a human body to the dietary fiber and has the effects of preventing the high blood pressure and the heart disease, preventing the arteriosclerosis, easing the constipation and enhancing the human immunity after long-term eating.

The invention discloses a pharmaceutical composition, and a preparation method, a preparation and application thereof. The pharmaceutical composition comprises the following bulk drugs by weight: 15 to 24 parts of taxillus, 15 to 24 parts of Radix Astragali, 10 to 15 parts of prepared fleece flower root, 8 to 15 parts of raw white peony root, 12 to 18 parts of stir-fried eucommia bark, 8 to 12 parts of Chinese angelica, 3 to 8 parts of Ligusticum wallichii, 8 to 12 parts of red sage root, 8 to 12 parts of gastrodia tuber, 15 to 20 parts of uncaria and 15 to 20 parts of fleeceflower stem. The pharmaceutical composition is prepared through extraction, concentration and drying. The preparation method comprises the following steps: pretreatment, extraction, concentration and drying. The preparation is a tablet, powder, oral liquid, capsule, granule, pill or honeyed pill prepared from the pharmaceutical composition and pharmaceutically acceptable adjuvant. The pharmaceutical composition is applied to preparation of drugs used for treating hypertension and target-organ damages caused by hypertension, e.g., cerebrovascular diseases, hypertensive heart diseases and hypertensive renal damage. Through combination and cooperation of the bulk drugs of the pharmaceutical composition, the pharmaceutical composition is capable of nourishing yin at first and reducing yang next, enables the kidney and brain to be nourished and the liver to be calmed, nourishes the liver and the kidney, extinguishes wind and dredges collaterals; so high blood pressure is lowered.

The invention discloses a traditional Chinese medicine combination used for curing heart disease, which is characterized in that the invention is prepared by the following compositions in portions by weight: 60-100 portions of rehmanniae vaporata, 30-50 portions of Chinese yam rhizome, 30-50 portions of common macrocarpium, 13-18 portions of cortex moutan, 13-18 portions of China root green birerrhizome, 13-18 portions of alisma orientale, 8-12 portions of cassia bark, 2-5 portions of hairy antler, 2-5 portions of tortoise plastron, 1-3 portions of schisandra chinensis and 1 portion of amomum villosum powder. The traditional Chinese medicine combination of the invention essentially cures coronary heart disease, pulmonary heart disease, rheumatic heart disease as well as hypertensive heart disease and congenital heart disease; the invention reaches 100 percent efficiency and 95 percent cure rate within one year when the heart disease attacks; symptoms of 5 percent of aged patients andpatients who have two long duration of disease and systemic failure can be promoted, thus prolonging life-span.

The invention discloses an agilawood moxa stick for preventing and treating cardiovascular diseases. The agilawood moxa stick is prepared from the following raw materials in parts by weight of 20-90 parts of agilawood, 10-80 parts of moxa, 1-20 parts of radix salviae miltiorrhizae, 1-20 parts of folium ginkgo and 1-10 parts of saffron crocus. Moxibustion is carried out on corresponding acupuncture points, the used medicine does not pass through intestines and stomach, so that toxic and side effects are avoided, and cardiovascular diseases such as coronary heart disease, hypertensive heart disease and rheumatic heart disease caused by qi deficiency and blood stasis are effectively prevented and treated in a targeted mode.

There is provided the use of a functional thylakoid extract, particularly in admixture with a physiologically acceptable carrier, in pharmaceutical application, in the treatment of cardiovascular diseases, and method for the treatment thereof. The cardiovascular diseases (CVD) may comprise several diseases associated with inflammation of the heart or arteries and include coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack), atherosclerosis, stroke, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, heart arrhythmia, congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease, and venous thrombosis.