33 results about "Auricular fibrillation" patented technology

The invention relates to a remote and hierarchical accurate follow-up visit management system for chronic cardiovascular diseases, in particular to remote and accurate follow-up visit of various hospitals, communities or even family members for high-risk patients subjected to mechanotherapy or intervention operations of chronic cardiac failure, auricular fibrillation and cardiovascular diseases. The system comprises a health cloud server, a hierarchical diagnosis and treatment management system and application terminal equipment; multi-permission is set on a client and a server; the system is linked through WiFi (Wireless Fidelity) and / or a network; the health cloud server is provided with a data import function, an information collection function and a data statistic function; and a hierarchical health management platform is constructed. The system can carry out real-time health monitoring, assessment, consultation and diagnosis and treatment at any time and any place on health conditions of chronic disease patients, especially chronic cardiovascular disease patients, provides convenient, reliable, considerate and inexpensive digital health care services and lays a foundation for establishment of an internet hospital.

The invention discloses a rapid linear radio-frequency ablation electrode, which aims at solving the technical problem of rapid and continuous ablation treatment. In the invention, an electrode tube consists of an ablation section formed by triangular bottom sides and a manipulation section formed by two bevel sides, wherein the ablation section is provided with annular electrodes at intervals; the electrodes are provided with temperature sensors; the annular electrodes is connected with a radio-frequency apparatus through leads and the temperature sensors are connected with the radio-frequency apparatus through temperature sensor leads; a bandlet made of elastic material is arranged in the center of the ablation section; the ablation section formed by the triangular bottom sides is expanded outward to be an arc shape by the bandlet; the length of the bandlet is extended to the junction of two triangular bevel sides; two end parts of the two bevel sides are connected with pull wires; and the other ends of two pull wires are fixed on a control handle. Compared with the prior art, the invention can reliably and continuously carry out vein isolation, reduce the relapse rate of the auricular fibrillation treatment, increase the continuousness of eliminating scar lines compared with single electrode, completely isolate ablation regions, keep ablation rings integral, has convenient operation and ensures that the operation is rapidly completed.

A RF electrode for treating atrial fibrillation is composed of a silica rubber tube, a plastic rod in said silica rubber tube, a plastic handle, PCB fixed to the handle, a RF head and 7 RF tubes on said silica rubber tube at intervals, RF connectors between two adjacent RF tubes, and two temp-measuring thermocouples.

The invention discloses a wearable device and signal processing method of assessing heart health by heartbeat signals, which comprises a motion state sensor that is used to detect whether a user is in the motion state; a heart rate sensor that is used to detect the users' heartbeat interval signals; a memory that is used to store calculus program of data processing, comparison and analysis and database; a microprocessor that is used to calculate, filter and judge signals and a feedback module that display or warn judgments. The wearable device can constantly detect the mobile state and heartbeat state of users, and detect their heart rates and determine the users' heart health in non-mobile state, for example: analyzing if they suffer from auricular fibrillation.

The invention relates to a Chinese medicinal preparation and process for preparation, wherein the main raw materials include pinellia tuber, fresh ginger, pilose asiabell root, astragalus root, bamboo shavings, immature bitter orange, dried orange peel, licorice root, poria cocos wolf and jujube, and can be used for treating coronary disease and auricular fibrillation.

The invention relates to a traditional Chinese medicine capsule used for treating atrial fibrillation, which is characterized in that: concentrated solution is extracted from red ginseng, kushen, shizandra, cassia twig, Mongolian snakegourd fruit, dwarf lilyturf root, radix glycyrrhizae preparata, fried spine date seed, salvia miltiorrhiza, dried rehmannia rhizome, Chinese goldthread rhizome, epimedium, motherwort and so on, and extract is prepared; and the traditional Chinese medicine capsule is obtained after drying, crushing, sterilization and encapsulation.

The invention belongs to the medical preparation, in particular to a Chinese herbal preparation- <BI QI WAN> capsules for treating coronary heart disease. The medicine is prepared by Fructus Trichosanthis, Rhizoma Pinelliae, Bulbus Allii Macrostemi and Radix Notoginseng. The invention is used for treating coronary heart disease and angina for 43 cases, acute left heart insufficiency and pneumonedema for 21 cases, acute arrhythmia such as auricular fibrillation, multi-source multi-type ventricular premature beats, ventricular tachycardia, ventricular fibrillation and severe nodal bradyrhythmia for 36 cases, all 100 cases, effective 88 cases and the general effective rate 88 percent.

The invention discloses a familial auricular fibrillation gene diagnosis kit, and is characterized in that the invention relates to the diagnosis kit for detecting familial auricular fibrillation genes by a large-scale parallel sequencing platform NGS technique. The kit is mainly characterized in that: A, a capture probe is uniquely designed and prepared and aims at all exon fragments of genes ABCC9, GJA5, KCNA5, KCNE2, KCNJ2, KCNQ1, NPPA and SCN5A; B, a connector with a label sequence is uniquely designed; C, a probe sequence is subjected to PCR amplification by universal primers; and D, a uniquely designed target fragment after mixing is subjected to capture operation.

The invention belongs to the field of medicines and particularly relates to a capsule of a traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases. The capsule is prepared from the following components by weight: tatarinow sweetflag rhizome, salvia miltiorrhiza bunge, platycladi seed, polygala tenuifolia, liriope, poria with hostwood, pollen typhae, tortoise shell, dragon bones, purslane, rehmanniae praeparatum, antler, and acanthopanax, which are respectively 1.5 parts; szechuan lovage rhizome, coptis chinensis, amur corktree bark, pinellia ternate, corydalis tuber, rhizoma curcumae longae, angelica sinensis, astragalus mongholicus, spina date seed, twotooth achyranthes root, white paeony root, earthworm, ginseng, teasel root, mulberry leaf, rhizoma polygonati, rehmanniae vaporata, zedoary, semen cassiae, tuber fleeceflower stem, leonurus, herba epimedii, rhizoma drynariae and bupleurum, which are respectively 1.3 parts; elecampane, rhizoma atractylodis, fried bighead atractylodes rhizome, bitter orange, polygonum cuspidatum, dried orange peel, hairyvein agrimony and purple perilla, which are respectively 1 part; and capillary artemisia and pearl, which are respectively 0.5 part. The preparation has the advantages of wide and rapid curative effect and high cure rate, is a pure traditional Chinese medicine preparation without any toxicor side effect and is suitable for arrhythmia, auricular fibrillation, ventricular conduction block, coronary heart disease, coronary atherosclerotic heart disease (angina and myocardial infarction),mitral valve stenosis, mitral valve insufficiency and hypertensive heart disease complications.

The invention relates to the technical field of electro cardio detection, in particular to a perimeter mapping method for auricular fibrillation. A cardiac chamber three-dimensional electro-anatomicalmapping system and a catheter with a magnet are included, and an electro cardio analysis system comprises a continuous rule analyzing module, a perimeter analyzing module and an interruption rule analyzing module. The perimeter mapping method for auricular fibrillation comprises the steps that during auricular fibrillation, atrial ordered excitation and disordered excitation portions are distinguished, during auricular fibrillation, some parts continue to be excited regularly, some parts are excited regularly or irregularly, some parts are irregular all the time, the probability that the partwhich is excited regularly at high frequency is a trigger focus is large, the parts excited regularly with the large perimeter are excited passively and are not foci, and the irregular parts with various perimeters are passively excited or are independent channels. Cardiac chamber ordered excitation and disorder excitation during auricular fibrillation are displayed on an atrial three-dimensionalmodel so as to position the source of the trigger focus, the atrial excitation conduction rules during auricular fibrillation are explained, and therefore the novel thought is supplied to radio frequency ablation during auricular fibrillation.

The invention specifically relates to a traditional Chinese medicine for treating auricular fibrillation, which belongs to traditional Chinese medicines. The traditional Chinese medicine is characterized by comprising the following components by weight: 5 to 15 g of red sage root, 5 to 15 g of Chinese angelica and 5 to 15 g of unprocessed rehmannia root. The traditional Chinese medicine is prepared by washing the carefully chosen red sage root, Chinese angelica and unprocessed rehmannia root, drying the cleaned red sage root, Chinese angelica and unprocessed rehmannia root in the air and carrying out grinding to obtain 100-mesh fine powder. 1 part of the powder is orally taken twice each day. The traditional Chinese medicine is prepared according to the differentiation traditional Chinese medicine theory and has the advantages of simple composition, easy availability of raw materials, low cost, a good curative effect, no toxic and side effects and capacity of effectively treating auricular fibrillation.

A human pathogenic gene of auricular fibrillation, which is a mutant of KCNQ1 gene, its nucleotide sequence and coded protein, and its preparing process and application are disclosed. The preparing process and application of its cell model and animal model, and the KCNQ1S14OG-KCNE1(Iks) composition with function gain are also disclosed.

The invention relates to novel application of a medicine, and in particular relates to an adjuvant treatment effect of tofacitinib on senile degenerative valvular disease. A clinical trial research shows that while conventional treatment is carried out on a patient with the senile degenerative valvular disease, the tofacitinib can be given for adjuvant treatment; the tofacitinib can be used for remarkably treating lung extravasated blood and pleural effusion symptoms of the patient with the senile degenerative valvular disease; various arrhythmia including auricular fibrillation and the like, atrial hypertrophy and ventricular hypertrophy are effectively relieved; the recurrence rate of the disease can be reduced, and the life quality of the patient is improved.

The invention provides a pharmaceutical composition for treating cardiovascular and cerebrovascular diseases, its preparing process and quality control method, wherein Dipyridamole and significant parts of herba erigerontis flavones are employed in combination to obtain various dose forms of injections and oral administration preparations. The composite preparation is mainly used for treating cerebral thrombus, cerebral infarction, cerebral hemorrhage, hemiplegia, senile dementia, angina pectoris caused by coronary disease, myocardial infarction, auricular fibrillation, viral myocarditis, pulmonary heart disease, retina venous clogging, hepatorenal syndrome, diabetes and complications. The preparation of the invention has the advantages of high purity, ensured constituents, controllable quality, improved treatment effect, wider range of safely, and less fluctuation of treatment effects.

The invention relates to an asymmetric bidiscoidal left atrial appendage occlusion device, which comprises a left atrium face disc (1), a waist connector (2) and a left atrial appendage face disc face (3), wherein the left atrium face disc (1), the waist connector (2) and the left atrial appendage face disc face (3) have netty structures woven by alloy wires; the left atrium face disc (1) has a disc structure, the disc face is arc-shaped, the circle center of disc face is inward concave, the center of the disc is a disc (4), and the inner seam of the disc is sealed by PTFE a film; the left atrial appendage face disc face (3) is trumpet-shaped; and the left atrium face disc (1) and the left atrial appendage face disc face (3) are connected by the waist connector (2). The alloy wires are made of nickel-titanium alloy. The asymmetric bidiscoidal left atrial appendage occlusion device can solve the problem of treating thrombus caused by auricular fibrillation.

The invention discloses a medicine for treating heart-Yin deficiency type auricular fibrillation. The medicine comprises radix rehmanniae, platycladi seeds, fried jujube kernels, asparagus cochinchinensis, radix ophiopogonis, Chinese angelica, the root of straight ladybell, radix scrophulariae, the root of red-rooted salvia, polygala tenuifolia, ligusticum wallichii, magnetite, dens draconis and amber powder. The medicine in the invention can obviously improve flustered, chest tightness and hard breathe symptoms of AF patients, can reduce the clinical seizure time of the AF patients, and can obviously reduce expression of inflammatory factors in serum of patients with auricular fibrillation; therefore, the symptoms when auricular fibrillation occurs can be effectively relieved; the seizurefrequency of auricular fibrillation is reduced; the survival quality of patients is improved; and the medicine has high practicability and popularization.

Adenosine A2A receptor antagonists are useful for the preparation of medicaments against atrial fibrillation in mammals, including humans. It has been found that the adenosine A2A receptor is present in human atrial cardiomyocytes and participates in the pathological mechanisms underlying atrial fibrillation. An advantage of using A2A antagonists over other agents known in the art is that the A2A antagonists specifically target patients with atrial fibrillation.

The invention discloses application of a CXCR2 gene in preparation of a diagnosis kit or a treatment drug composition for arrhythmia-related diseases. The inventor discovers that after the CXCR2 geneis knocked out, the atrial fibrosis is improved; further, after the CXCR2 gene is knocked out, the mRNA level of an atrial fibrosis marker is also obviously improved; furthermore, an effect of protecting auricular fibrillation is achieved, which shows that CXCR2 can be used as a drug composition target applied to clinical treatment of the heart-related diseases.

The invention relates to a plate electrode of an electric cardioversion defibrillator. The plate electrode comprises a first plate electrode body and a second plate electrode body. The bottom surface of the first plate electrode body is fixedly connected with an insulating plate, the vertex of the arc of the first plate electrode body is electrically connected with a first connecting plate through an insulating wire, and a first insulating handle is fixedly connected with the vertex of the arc of the first plate electrode body and surrounds the insulating wire. The center of the second plate electrode body is electrically connected with a second connecting plate through an insulating wire, a second insulating handle is connected with the center of the top surface of the second plate electrode body and surrounds the insulating wire, and a second insulating plate is arranged on the upper surface of the second plate electrode body with the second insulating handle as the center. The plate electrode is innovated, only the small power 30 J is needed for cardioversion of auricular fibrillation and supraventricular tachycardia, injury to a patient is small, and recovery is fast.

The invention belongs to the technical field of medicines, and particularly relates to a traditional Chinese medicine composition for treating phlegm-qi stagnation type hyperthyroidism with auricular fibrillation. The traditional Chinese medicine composition is prepared from, by weight, 4-8 parts of common wrightia roots or stems, 4-8 parts of kumquat leaves, 4-8 parts of jasminum officinale L.var. grandiflorum (L.) Kobuski (J. grandiflorum L.), 4-8 parts of roots of cissus repens, 4-8 parts of delavay gerbera roots, 4-8 parts of herb of nutgrass flatsedge, 4-8 parts of roots of oblique rhychoglossum, 4-8 parts of herb of rattlesnake plantain, 4-8 parts of fruit of celastrus flagellaris, 4-8 parts of ziziphora clinopodioides Lam. and 4-8 parts of licorice roots. All the medicinal materials are cooperatively used to jointly achieve the effects of promoting qi circulation, removing depression, reducing phlegm, resolving masses, calming the heart and soothing the nerves; the average heart rate can be decreased, and the functional level of the thyroid gland can be recovered; no influence is generated to security indexes, and the safety is good.

The invention belongs to the field of medical technology and particularly relates to a traditional Chinese medicine composition for treating heart-spleen deficiency type hyperthyroidism complicating auricular fibrillation. The traditional Chinese medicine composition consists of the following traditional Chinese medicines in parts by weight: 4-8 parts of grifola frondosa, 4-8 parts of parish's ironweed, 4-8 parts of common triplostegia root, 4-8 parts of semen thujae koraiensis, 4-8 parts of medical angiopteris rhizome, 4-8 parts of ficus esquiroliana, 4-8 parts of satyrium henryi schlecht., 4-8 parts of cyperus rotundus, 4-8 parts of oblique rhynchoglossum root, 4-8 parts of goodyera, 4-8 parts of celastrus flagellaris rupr., 4-8 parts of ziziphora clinopodioides lam and 4-8 parts of liquorice. The traditional Chinese medicines together realize the functions of invigorating spleen and nourishing heart, tonifying and replenishing qi and blood, softening hardness and dissipating mass and calming heart and tranquilizing mind. The traditional Chinese medicine composition can reduce the average heart beat and recover the thyroid function level while the safety index is not influenced and the safety is good.

The invention belongs to the technical field of medicine and particularly relates to a traditional Chinese medicine composition for treating heart-yin deficiency type hyperthyroidism combined with auricular fibrillation. The traditional Chinese medicine composition comprises, by weight, 4-8 parts of flos edgeworthlae, 4-8 parts of roots of parishs ironweed, 4-8 parts of radix triplostegiae glanduliferae, 4-8 parts of roots or all-grass of aletris spicata (thunb.) franch., 4-8 parts of cattle horns moss, 4-8 parts of roots of achyranthes aspera L., 4-8 parts of tuber of satyrium henryi schlecht., 4-8 parts of oblique rhychoglossum roots, 4-8 parts of creeping rattlesnake plantain herbs, 4-8 parts of fruits of calastrus flagellaris rupr., 4-8 parts of all-grass of ziziphora clinopodioides Lam. and 4-8 parts of liquorice roots. According to the traditional Chinese medicine composition, all constituents act in a synergistic mode to achieve the effects of enriching yin, nourishing the heart, softening hardness to dissipate stagnation, tranquilize the mind and soothing the nerves. The average heart rate can be lowered, the thyroid function level can be recovered, the safety index is not influenced, and safety performance is good.

The invention discloses a kit for detecting A75S mutation of an SCN4B gene and belongs to the field of molecular biologics. The kit comprises Taq DNA polymerase, 10*PCR buffer liquid, Mg<2+>(MgCl2), dNTP mixture, H2O, an A75S endogenesis upstream primer F1, an A75S endogenesis downstream primer R1, an exogenous upstream primer FO and exogenous downstream primer RO, wherein the sequences of the primers are as shown in SEQ ID NO.1-4. The kit is applicable to nearly all PCR instruments and is low in equipment requirement, the operation feasibility of the kit is greatly improved, and the cost of the kit is also greatly reduced when being compared with a detection method which needs precise equipment. The kit can be applied to primary detection on A75S mutation of the SCN4B gene, diagnosis bases are provided for SCN4B A75S gene mutation associated auricular fibrillation diseases, and the diagnosis efficiency is improved.

The invention relates to a plate electrode of an electric cardioversion defibrillator. The plate electrode comprises a first plate electrode body and a second plate electrode body. The bottom surface of the first plate electrode body is fixedly connected with an insulating plate, the vertex of the arc of the first plate electrode body is electrically connected with a first connecting plate through an insulating wire, and a first insulating handle is fixedly connected with the vertex of the arc of the first plate electrode body and surrounds the insulating wire. The center of the second plate electrode body is electrically connected with a second connecting plate through an insulating wire, a second insulating handle is connected with the center of the top surface of the second plate electrode body and surrounds the insulating wire, and a second insulating plate is arranged on the upper surface of the second plate electrode body with the second insulating handle as the center. The plate electrode is innovated, only the small power 30 J is needed for cardioversion of auricular fibrillation and supraventricular tachycardia, injury to a patient is small, and recovery is fast.

The invention provides a pharmaceutical composition for treating cardiovascular and cerebrovascular diseases, its preparing process and quality control method, wherein Troxerutin and significant parts of herba erigerontis flavones are employed in combination to obtain various dose forms of injections and oral administration preparations. The composite preparation is mainly used for treating cerebral thrombus, cerebral infarction, cerebral hemorrhage, senile dementia, angina pectoris caused by coronary disease, myocardial infarction, auricular fibrillation, viral myocarditis, pulmonary heart disease, retina venous clogging, thrombotic phlebitis, capillary vessel hemorrhage, hepatorenal syndrome, diabetes and complications. The preparation of the invention has the advantages of high purity, ensured constituents, controllable quality, improved curative effect, wider range of safely, and less fluctuation of treatment effects.

The invention relates to novel application of a medicine, and in particular relates to an adjuvant treatment effect of tofacitinib on senile degenerative valvular disease. A clinical trial research shows that while conventional treatment is carried out on a patient with the senile degenerative valvular disease, the tofacitinib can be given for adjuvant treatment; the tofacitinib can be used for remarkably treating lung extravasated blood and pleural effusion symptoms of the patient with the senile degenerative valvular disease; various arrhythmia including auricular fibrillation and the like, atrial hypertrophy and ventricular hypertrophy are effectively relieved; the recurrence rate of the disease can be reduced, and the life quality of the patient is improved.

The invention belongs to the technical field of medicine, and particularly relates to a traditional Chinese medicine composition for treating liver qi stagnation type hyperthyreosis accompanied by auricular fibrillation. The traditional Chinese medicine composition is prepared from, by weight, 4-8 parts of herb of nutgrass galingale, 4-8 parts of jasminum officinale flower bud, 4-8 parts of celastrus flagellaris fruit, 4-8 parts of corylopsis sinensis root, 4-8 parts of all grass of david vetchling, 4-8 parts of manglietia yuyuanensis law fruit, 4-8 parts of fiveleaf akebia fruit, 4-8 parts of root of oblique rhychoglossum, 4-8 parts of wikstroemia nutans flower and 4-8 parts of liquorice root. The medicinal materials are combined to soothe liver-qi stagnation, regulate qi and loosen the center, resolve hard lump and calm mind. By the adoption of the traditional Chinese medicine composition, the average heart rate can be reduced, the thyroid function level can be recovered, the security index is not affected, and safety performance is high.