Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Chinese medicinal composition for treatment of chronic heart failure and preparation method thereof

A chronic heart failure and composition technology, applied in the field of traditional Chinese medicine composition for treating chronic heart failure and its preparation, can solve the problems of inconvenient taking, slow effect, unsatisfactory curative effect, etc., achieve simple preparation method and improve chronic heart failure The effect of the model

Inactive Publication Date: 2017-04-26
中国人民解放军第一五二中心医院
View PDF1 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Commercially available Qili Qiangxin Capsules have the disadvantages of unsatisfactory curative effect, inconvenient taking and slow effect

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Chinese medicinal composition for treatment of chronic heart failure and preparation method thereof
  • Chinese medicinal composition for treatment of chronic heart failure and preparation method thereof
  • Chinese medicinal composition for treatment of chronic heart failure and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0024] The preparation method of above-mentioned Chinese medicine composition, in order to prepare 1000ml oral liquid, comprises the following steps:

[0025] Step 1, weigh the following components according to the parts by weight: 140-160 parts of ginseng, 180-200 parts of salvia miltiorrhiza, 180-200 parts of scallion, 240-260 parts of Tinglizi, 240-260 parts of poria cocos, 180-200 parts of curcuma parts, peach kernel 180-200 parts;

[0026] Step 2, decocting the weighed above-mentioned components with 8 times of water for 2-3 times, boiling for 20-40 minutes each time, filtering and merging each decoction, and concentrating at 80°C to a relative density of 1.15-1.30;

[0027] Preferably, decocting 3 times, 40 minutes each time, the extraction amount of the active ingredient hesperidin extracted under this extraction condition is the highest, which is 112.86 μg / 50g medicinal material.

[0028] Step 3, add ethanol to the concentrated solution at room temperature, stir while...

Embodiment 1

[0074] Step 1, weighing the following components according to parts by weight: 150g ginseng, 200g salvia miltiorrhiza, 200g scallion, 250g Tinglizi, 250g poria cocos, 200g curcuma, 200g peach kernel;

[0075] Step 2, decocting the weighed above-mentioned components with 8 times of water for 3 times, boiling for 40 minutes each time, filtering and merging the decoction for 3 times, and concentrating at 80°C to a relative density of 1.20;

[0076] Step 3, add ethanol to the concentrated solution at room temperature, stir while adding, so that the ethanol content is 60%, leave it for more than 24 hours, and recover the ethanol from the supernatant until it has no alcohol smell;

[0077] Step 4: Add simple syrup, adjust the pH value to 5.0-7.0, add water to 1000ml, stir well, let stand, filter, fill, and sterilize at 100°C for 30 minutes.

Embodiment 2

[0079] Step 1, weigh the following components according to the parts by weight: ginseng 140g, salvia miltiorrhiza 180g, scallion 180g, Tinglizi 240g, poria cocos 240g, curcuma 180g, peach kernel 180g;

[0080] Step 2, decocting the weighed above-mentioned components with 8 times water for 2 times, boiling for 30 minutes each time, filtering and merging the decoction twice, and concentrating at 80°C to a relative density of 1.15;

[0081] Step 3, add ethanol to the concentrated solution at room temperature, stir while adding, so that the ethanol content is 60%, leave it for more than 24 hours, and recover the ethanol from the supernatant until it has no alcohol smell;

[0082] Step 4: Add simple syrup, adjust the pH value to 5.0-7.0, add water to 1000ml, stir well, let stand, filter, fill, and sterilize at 100°C for 30 minutes.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a Chinese medicinal composition for treatment of chronic heart failure and a preparation method thereof. The Chinese medicinal composition is composed of the following components by weight: 140-160 parts of ginseng, 180-200 parts of Salvia Miltiorrhiza, 180-200 parts of Allium macrostemon, 240-260 parts of semen lepidii, 240-260 parts of Poria cocos, 180-200 parts of curcuma zedoary, and 180-200 parts of peach kernel. The preparation method includes: weighing the components and adding water for decoction, concentrating the decoction to obtain a concentrated solution; adding ethanol into the concentrated solution to conduct extraction, recovering ethanol from the supernatant recycling ethanol till no alcohol flavor; adding simple syrup into sinking liquid, adjusting the pH value, and performing filtering, thus obtaining the Chinese medicinal composition. The Chinese medicinal composition provided by the invention can significantly improve the chronic heart failure model of rats, has certain treatment effect on chronic heart failure, and can be used for treatment of cardiac insufficiency and chronic cardiac failure caused by coronary heart disease, hypertensive heart disease, rheumatic heart disease, cor pulmonale and cardiomyopathy, etc.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine compositions, and in particular relates to a traditional Chinese medicine composition for treating chronic heart failure and a preparation method thereof. Background technique [0002] As the proportion of the elderly increases, the morbidity and mortality of cardiovascular and cerebrovascular diseases also increase. Heart failure is the terminal stage of various cardiovascular diseases such as rheumatic heart disease, cardiomyopathy, and coronary heart disease. [0003] At present, there are many kinds of western medicines for the treatment of heart failure, which have quick effects but short duration and relatively large side effects. Commercially available Qili Qiangxin Capsules have the disadvantages of unsatisfactory curative effect, inconvenient taking and slow effect. Contents of the invention [0004] In view of this, the present invention aims at the above problem...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P9/04
CPCA61K36/9066A61K36/076A61K36/258A61K36/31A61K36/537A61K36/736A61K36/8962A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 赵京生郭长升易伟国魏远亮张正臣
Owner 中国人民解放军第一五二中心医院
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com