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54 results about "Allium macrostemon" patented technology

Allium macrostemon, English name long-stamen chive, is a species of wild onion widespread across much of East Asia. It is known from many parts of China, as well as Japan (incl Ryukyu Islands), Korea, Mongolia, Tibet and Primorye. It has been collected from elevations ranging from sea level to 3000 m.

Traditional Chinese medicine composition for preventing and treating atherosclerosis and plaque formation and application thereof

The invention discloses a traditional Chinese medicine composition for preventing and treating atherosclerosis and plaque formation and application thereof. The traditional Chinese medicine composition comprises the following traditional Chinese medicine components in parts by weight: 10-15 parts of peach kernel, 7-12 parts of safflower, 12-18 parts of angelica sinensis, 15-25 parts of radix rehmanniae, 12-18 parts of ligusticum wallichii, 10-15 parts of radix paeoniae rubra, 12-18 parts of radix cyathulae, 12-18 parts of platycodon grandiflorum, 12-18 parts of radix bupleuri, 10-15 parts of bran-fried fructus aurantii, 4-8 parts of honey-fried licorice root, 10-15 parts of ginseng, 8-12 parts of poria cocos, 4-8 parts of rhizoma zingiberis, 10-15 parts of rhizoma cyperi, 12-18 parts of radix curcumae, 10-15 parts of cortex albiziae, 12-18 parts of rhizoma pinelliae preparata, 12-18 parts of exocarpium citri grandis, 20-30 parts of 25 parts of allium macrostemon, 25-35 parts of corn stigma, 15-25 parts of plantain herb and 25-35 parts of oyster; based on the theory of traditional Chinese medicine, all traditional Chinese medicine raw materials are screened, and through the combined action of all the raw materials, the traditional Chinese medicine composition has a remarkable curative effect on atherosclerosis and takes effect quickly.
Owner:陈钧淇

A traditional chinese medicine composition for improving hypertension

This invention discloses a traditional Chinese medicine composition for improving hypertension, belonging to the field of traditional Chinese medicine compound preparation technology. This invention targets the core pathogenesis of hypertension caused by phlegm-dampness obstruction and peripheral microcirculation disorders, leading to abnormal activation of the hypothalamic-sympathetic-cardiac axis and compensatory cardiac hypertensive. The treatment principle is to resolve phlegm and dampness, and invigorate blood circulation. It is formulated with nutmeg, allium macrostemon, amomum villosum, peach kernel, safflower, platycodon grandiflorus, angelica dahurica, and tangerine peel. This combination can dredge the meridians, improve peripheral blood supply, and alleviate cardiac compensatory pumping, thus addressing hypertension caused by phlegm-dampness obstruction at its root. The formula is scientifically formulated, highly safe, and easy to prepare, making it suitable for long-term treatment and industrial promotion.
Owner:YINGXUAN TRADITIONAL CHINESE MEDICINE TECHNOLOGY (HENGZHOU) CO LTD

Medicine for treating heart of human body

The invention discloses a medicine for treating the heart of a human body, and particularly relates to the field of medicines, the medicine is prepared from the following components in percentage by mass: 13.8% of radix salviae miltiorrhizae, 4.1% of allium macrostemon, 8.3% of semen trichosanthis, 2% of polygala tenuifolia, 8.3% of radix ophiopogonis, 2% of sandalwood, 6.9% of pericarpium citri reticulatae viride, 13.8% of lily, 8.3% of semen boitae, 10.4% of poria cocos, 8.3% of oriental cherry powder and 13.8% of earthworm, and the sum of the mass percentages of the components is 100%. According to the medicine for treating the heart of the human body, traditional Chinese medicine decoction pieces such as salvia miltiorrhiza, allium macrostemon, snakegourd seeds, polygala tenuifolia, radix ophiopogonis, sandalwood, pericarpium citri reticulatae viride, lily, platycladi seeds, poria cocos, oriental cherry powder and lumbricus are crushed and proportioned according to corresponding formula proportions and processes, so that the medicine plays the maximum effects of all the decoction pieces, is easier to take and absorb, and can be taken for a long time after being taken. The traditional Chinese medicine composition has obvious treatment effects on cardiac insufficiency, dyspnea, weakness, fatigue, angina pectoris, palpitation, palpitation and other problems caused by heart problems of heart disease patients, and can effectively treat coronary heart disease, myocardial ischemia, arrhythmia and other heart diseases.
Owner:ZHUHAI YUSHENG TRADITIONAL CHINESE MEDICINE HOSPITAL CO LTD

Traditional Chinese medicine composition for qi deficiency, blood stasis and phlegm stagnation type coronary heart disease as well as preparation method and application of traditional Chinese medicine composition

The invention belongs to the technical field of cardiovascular disease treatment medicines, and particularly relates to a traditional Chinese medicine composition for qi deficiency, blood stasis and phlegm stagnation type coronary heart disease as well as a preparation method and application thereof. The traditional Chinese medicine composition comprises codonopsis pilosula, astragalus membranaceus, dogwood, rhizoma anemarrhenae, platycodon grandiflorum, radix bupleuri, rhizoma cimicifugae, rhizoma sparganii, curcuma zedoary, cassia twig, trichosanthes kirilowii maxim, allium macrostemon, rhizoma pinelliae preparata, Chinese yam and honey-fried licorice root. The traditional Chinese medicine composition can tonify qi, activate blood, eliminate phlegm and resolve turbidity, can be used for treating qi deficiency, blood stasis and phlegm stagnation type coronary heart disease, and can treat both symptoms and root causes. Experiments prove that for a mouse with coronary heart disease, the traditional Chinese medicine composition can obviously improve the heart function of the mouse, and has the effects of inhibiting atherosclerosis and regulating lipid metabolism; for patients with qi deficiency, blood stasis and phlegm stagnation type coronary heart disease, the traditional Chinese medicine composition can improve the symptoms of chest pain and chest distress of the patients. Therefore, the traditional Chinese medicine composition can be used for preparing a medicine for treating qi deficiency, blood stasis and phlegm stagnation type coronary heart disease, and can also be used for preparing a medicine for regulating blood fat.
Owner:THE FIRST AFFILIATED HOSPITAL OF HENAN UNIV OF TCM

Traditional Chinese medicine compound for treating viral myocarditis

ActiveCN121401357BAntiviralsCardiovascular disorderViral MyocarditisCitrus medica
This invention provides a traditional Chinese medicine compound for treating viral myocarditis, belonging to the field of traditional Chinese medicine pharmaceutical technology. The compound consists of Forsythia suspensa, Fagopyrum dibotrys, Pseudostellaria heterophylla, Rhodiola rosea, Citrus medica, Allium macrostemon, Poria cocos, Gynostemma pentaphyllum, Salvia miltiorrhiza, Dalbergia odorifera, Cynanchum paniculatum, and Valeriana. This traditional Chinese medicine compound exhibits significant protective effects against viral myocarditis, specifically by significantly reducing damage to H9c2 cardiomyocytes caused by CVB3 virus. Its mechanism of action is closely related to downregulating the expression of inflammatory factors TNF-α and IL-6 and inhibiting the inflammatory response. Simultaneously, within the experimental concentration range, the compound shows no toxicity to cardiomyocytes, demonstrating good biocompatibility. Furthermore, this compound can significantly reduce myocardial tissue damage in a viral myocarditis model mouse by inhibiting the in vivo inflammatory response and regulating oxidative stress imbalance, providing a safe and effective new treatment option for the clinical treatment of viral myocarditis.
Owner:THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV

Appetizing allium macrostemon delicious food and making method thereof

The invention belongs to the field of food processing, and particularly relates to an appetizing allium macrostemon delicious food and a preparation method thereof. Alias of allium macrostemon include allium chinense, fire onion, allium ascalonicum, garlic sprout and the like, and the alias are different in different regions. The allium macrostemon is an underground bulb of a perennial herbaceous liliaceae plant, has a long leaf line, has purple florets, and is edible in tender leaves. The mature allium chinense is large, thick, white, glittering and translucent, spicy, tender and glutinous, and contains various nutrient substances such as sugar, protein, calcium, phosphorus, iron, carotene, vitamin C and the like. The longstamen onion bulb has the effects of promoting appetite, helping digestion, relieving greasiness, tonifying spleen, promoting appetite and the like. As the allium macrostemon is low in yield and high in edible value, the allium macrostemon is listed in a high-grade vegetable list in China, and is called lucid ganoderma in vegetables. The allium macrostemon, red pepper, green pepper, flat sharp bamboo shoot, green prickleyash, ginger and other carrier plants are scientifically prepared. The canned food is prepared by adopting low-temperature inactivation and sterile cold processing in the whole process of the preparation process. The problems that the allium macrostemon is low in yield, not easy to purchase and preserve freshness and pungent in taste are solved.
Owner:骆世林

Method for identifying different allium macrostemon bases and true and false products in allium macrostemon medicine including formula granules and application of different allium macrostemon bases and true and false products in allium macrostemon medicine

The invention provides a method for identifying different allium macrostemon bases and true and false products in allium macrostemon medicines including formula granules and application thereof, and the method comprises the following steps: (1) mixing a sample to be detected with a solvent, and extracting to obtain a test solution; (2) mixing the reference medicinal material with a solvent, and extracting to obtain a reference medicinal material solution; and (3) carrying out thin-layer chromatography on the test solution and the reference medicinal material solution, and judging the primitive and / or authenticity of the sample to be detected according to the detection result, the allium macrostemon base source comprises allium macrostemon (small garlic roots) and allium macrostemon (allium macrostemon). According to the identification method provided by the invention, allium macrostemon (small root garlic), allium macrostemon (allium macrostemon) and allium macrostemon adulterants, namely scirpus tabernaemontani and Chinese squill, can be rapidly and effectively identified, the detection result is accurate, the used reagent is low in toxicity and high in safety, and the condition that an experimenter is in contact with the toxic reagent can be reduced to the greatest extent.
Owner:BEIJING KANGRENTANG PHARMA

Granules for promoting blood circulation to remove meridian obstruction and preparation method thereof

The invention relates to granules for promoting blood circulation to remove meridian obstruction and a preparation method thereof. Ginkgo leaves, fried spina date seeds, astragalus membranaceus, radix puerariae, hawthorn, salvia miltiorrhiza, allium macrostemon, rhodiola rosea, fructus lycii, acanthopanax, schisandra chinensis and radix ophiopogonis are selected as raw materials, the raw materials are decocted, filtered, concentrated and granulated, the materials are all selected from natural traditional Chinese medicine components, the effects of promoting blood circulation to remove blood stasis and activating meridians to stop pain are achieved, and the traditional Chinese medicine composition has a remarkable curative effect on chest stuffiness, cardiodynia, dizziness, coronary heart disease and angina pectoris caused by blood stasis blocking collaterals. The traditional Chinese medicine composition has obvious curative effects on symptoms such as hypertension, hyperlipidemia and cerebral arteriosclerosis, has no side effect on the body, is simple in preparation method and low in production cost, and has application and popularization prospects.
Owner:HARBIN GAOZHENTANG TCM CLINIC CO LTD

Chinese herbal medicine freckle-removing cream and preparation method thereof

PendingCN122075358Alow recurrence rateStable freckle removal effectCosmetic preparationsAnthropod material medical ingredientsMedicinal herbsContinuous use
The embodiment of the invention discloses Chinese herbal medicine freckle-removing cream and a preparation method thereof. The Chinese herbal medicine freckle-removing cream is prepared from Chinese herbal medicine decoction liquor and a natural oil-in-water emulsion system, and the Chinese herbal medicine decoction liquor comprises the following medicinal materials: rehmannia, radix polygonati officinalis, Chinese waxgourd seed, stiff silkworm, caltrop, hawthorn, hairyvein agrimony, allium macrostemon, vine of multiflower knotweed, cortex albiziae, platycladi seed, lalang grass rhizome, perilla leaf, pepper and magnolia bark; the natural oil-in-water emulsifying system comprises the following raw materials: olive oil emulsifying wax, shea butter, jojoba oil, grape seed oil and vitamin E. Human body trials prove that the Chinese herbal medicine freckle-removing cream is fine and moist in skin feeling and not greasy after being smeared, and skin irritation reactions such as stabbing pain, redness and pruritus do not exist in the using process; after continuous use for 3 months, chloasma, sunburn and other color spots are obviously faded, the skin glossiness and fineness are obviously improved, and no obvious rebound occurs after the use is stopped; the composition is suitable for dry, oily, mixed and sensitive skin, and has good safety and tolerance.
Owner:梁敬

Traditional Chinese medicine composition as well as preparation method and application thereof

The invention provides a traditional Chinese medicine composition and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition comprises more than 30 Chinese herbal medicines such as radix bupleuri, murraya paniculata, codonopsis pilosula, allium macrostemon and cassia twig. The traditional Chinese medicine composition is mainly used for strengthening the spleen, excreting dampness, promoting intestinal tract movement and recovering normal operation of a nutrient absorption function, regulating normal operation of a digestion and absorption system of a human body and promoting transportation and transformation of the spleen and the small intestine by gradually controlling the pathogenesis of aplastic anemia, and plays a coordination and comprehensive treatment role from regenerated marrow to regenerated blood; and the pathogenesis of aplastic anemia is radically and thoroughly reversed, so that the body achieves the purpose of natural rehabilitation.
Owner:柯利洪

Traditional Chinese medicine composition for regulating abnormal lipid metabolism as well as preparation method and application of traditional Chinese medicine composition

The invention discloses a traditional Chinese medicine composition for regulating abnormal lipid metabolism as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition for regulating abnormal lipid metabolism is prepared from the following raw materials in parts by weight: 10-30 parts of polygonum cuspidatum; 5-15 parts of coptis chinensis; 10-25 parts of radix paeoniae rubra; 8-20 parts of pollen typhae; 8-25 parts of allium macrostemon; and 5-20 parts of dried orange peel. The preparation method of the traditional Chinese medicine composition for regulating the abnormal lipid metabolism comprises the following steps: adding water into the components in the traditional Chinese medicine composition, decocting and extracting, and concentrating, drying and crushing after extracting to obtain the traditional Chinese medicine composition for regulating the abnormal lipid metabolism. The traditional Chinese medicine composition disclosed by the invention is used for preparing medicines for regulating abnormal lipid metabolism. The traditional Chinese medicine composition disclosed by the invention has the characteristics of multiple targets, multiple pathways, toxicity reduction, efficacy enhancement and the like in treatment of the metabolic syndrome; the metabolic syndrome is improved through multiple effects of promoting blood circulation to remove blood stasis, dissolving turbidity and detoxifying; the medicine is used for treating metabolic syndrome patients mainly suffering from central obesity and covers a wide range of people.
Owner:SHANXI UNIV OF CHINESE MEDICINE

A medicinal and edible composition that warms the yang and dispels cold, and its preparation method.

PendingCN122272752ABiotechnologyYang deficiency
This invention discloses a warming and dispersing medicinal and edible composition and its preparation method. This invention relates to the field of traditional Chinese medicine health food technology. The active ingredients of the composition are extracted from the following medicinal and edible materials: 3-10 parts by weight of dried ginger, 2-8 parts by weight of cinnamon, 5-15 parts by weight of Allium macrostemon, and 10-30 parts by weight of Astragalus membranaceus. Small molecule extract particles are prepared through processes such as β-cyclodextrin inclusion and wet granulation, significantly improving the dissolution rate and bioavailability of the active ingredients. The product is also convenient to prepare, easy to carry, and suitable for long-term use. In terms of safety, all raw materials are medicinal and edible substances. Clinical trials have proven that the overall effective rate for symptoms of Yang deficiency such as aversion to cold, cold limbs, lethargy, and loose stools is over 94%, with no obvious toxic side effects. It can be safely used for daily health maintenance and auxiliary conditioning of those with Yang deficiency and cold constitution. Pure coconut powder is used as a flavoring material, resulting in a rich aroma and good taste.
Owner:张翠英

Separation and identification of steroidal saponins from allium macrostemon bunge and its application

The present application mainly relates to the separation and identification and application of active ingredients in traditional Chinese medicine, and specifically discloses a separation and purification of a steroidal saponin compound in Allii Macrostemonis Bulbus. According to the physical and chemical properties and high-resolution electrospray mass spectrometry (HR-ESI-MS), one-dimensional / two-dimensional nuclear magnetic resonance spectroscopy (1D- / 2D-NMR) and other spectral technologies, the structure of the compound is identified, the structure is analyzed and the molecular formula is determined, and finally named as Allii Macrostemonis Bulbus saponin U. The pharmacological activity of Allii Macrostemonis Bulbus saponin U is studied through in vitro cell experiments, and it is found that Allii Macrostemonis Bulbus saponin U significantly improves the cell viability of mouse hippocampal neurons after glutamate treatment, has good neuroprotective activity, and can be used for the preparation and application of anti-nerve injury drugs.
Owner:JILIN AGRICULTURAL UNIV

Traditional Chinese medicine compound and preparation for treating coronary heart disease as well as preparation method and application of traditional Chinese medicine compound and preparation

PendingCN121987718AComply with the treatment principles of traditional Chinese medicineSuitable for long-term conditioningPowder deliveryLyophilised deliveryMedicinal herbsSalvia miltiorrhiza
The invention relates to the technical field of pharmaceutical preparations, in particular to a traditional Chinese medicine compound and preparation for treating coronary heart disease and a preparation method and application of the traditional Chinese medicine compound and preparation. The traditional Chinese medicine composition is prepared from the following medicinal materials in parts by weight: 10-30 parts of astragalus membranaceus, 5-15 parts of rhodiola rosea, 10-30 parts of salvia miltiorrhiza, 5-15 parts of ligusticum wallichii, 10-30 parts of trichosanthes kirilowii maxim, 5-15 parts of allium macrostemon, 5-15 parts of folium ginkgo, 10-30 parts of radix puerariae, 10-30 parts of radix ophiopogonis, 3-10 parts of schisandra chinensis, 15-30 parts of oyster, 5-15 parts of cassia twig and 3-10 parts of liquorice. Animal experiment results show that the traditional Chinese medicine composition provided by the invention has remarkable and multi-aspect curative effect advantages in the aspect of treating a coronary heart disease rat model. The traditional Chinese medicine composition not only can enhance myocardial contractility and recover heart blood pumping function, but also can inhibit inflammatory response, relieve myocardial damage, effectively relieve myocardial structure damage and protect myocardial tissue integrity. In addition, a proportional experiment result shows that the effect of the composition provided by the invention can be obviously weakened by losing any medicine pair, so that all the medicines in the formula cannot be absent.
Owner:HEILONGJIANG UNIV OF CHINESE MEDICINE

A traditional Chinese medicine composition for treating ulcerative colitis, its preparation method, combined drugs, and applications.

ActiveCN118615390Breduce inflammationprotect or repair damageOrganic active ingredientsAntipyreticClinical studyMucosal inflammation
This invention discloses a traditional Chinese medicine composition for treating ulcerative colitis, its preparation method, combined drugs, and applications. The traditional Chinese medicine composition for treating ulcerative colitis of this invention is made from the following raw materials in parts by weight: Astragalus membranaceus 13-26 parts, Lonicera japonica 10-20 parts, Sargentodoxa cuneata 10-20 parts, Prunus mume 8-16 parts, Agrimonia pilosa 8-16 parts, Allium macrostemon 6-12 parts, Platycodon grandiflorus 6-12 parts, Coptis chinensis 3-6 parts, and Panax notoginseng powder 1-3 parts. An animal model of ulcerative colitis was constructed using DSS induction, and the results showed that the traditional Chinese medicine composition of this invention has a certain therapeutic effect on ulcerative colitis. Clinical studies showed that the traditional Chinese medicine composition of this invention, used in combination with mesalazine enteric-coated tablets, can reduce the modified Mayo score and serum inflammatory markers in patients with active ulcerative colitis, improve colonic mucosal inflammation and gastrointestinal symptoms, and effectively treat active ulcerative colitis of the damp-heat type.
Owner:BEIJING UNIV OF CHINESE MEDICINE

A traditional Chinese medicine composition for removing vascular plaques and its preparation method

The present invention discloses a traditional Chinese medicine composition for removing vascular plaques and a preparation method thereof. The traditional Chinese medicine composition for removing vascular plaques is made from the following raw materials in parts by weight: 8-12 parts of nattokinase, 8-12 parts of chrysanthemum, 6-10 parts of dandelion, 6-10 parts of honeysuckle, 6-10 parts of kudzu root, 4-8 parts of fingered citron, 6-10 parts of citron, 4-8 parts of peach kernel, 10-14 parts of angelica, 10-14 parts of hawthorn, 6-10 parts of allium macrostemon, 8-12 parts of wolfberry fruit, 4-8 parts of cornel, 4-8 parts of cinnamon, 10-14 parts of Chinese date, and also discloses the preparation method. After the medicinal materials are extracted, nattokinase is added and prepared into one of tablets, capsules and granules. The present invention can clear heat and detoxify, resolve phlegm, promote blood circulation to remove blood stasis, and nourish the liver and kidney, and has an eliminating effect on carotid artery plaques formed by senile carotid atherosclerosis of liver-kidney yin deficiency type, with good effects.
Owner:NANJING UNIV OF TRADITIONAL CHINESE MEDICINE

A traditional Chinese medicine preparation for treating coronary heart disease and a preparation method thereof

The present application belongs to the technical field of traditional Chinese medicine preparation, and particularly relates to a traditional Chinese medicine preparation for treating coronary heart disease and a preparation method thereof. The traditional Chinese medicine preparation comprises the following raw materials in parts by weight: 22-28 parts of Astragalus membranaceus, 20-25 parts of Prenanthes altissima, 13-18 parts of Panax notoginseng, 10-15 parts of small Rhododendron, 8-13 parts of Radix Paeoniae Rubra, 7-12 parts of Allium macrostemon, and 3-8 parts of Glycyrrhiza uralensis. In the traditional Chinese medicine preparation, Astragalus membranaceus and Prenanthes altissima are the monarch drugs for tonifying qi and promoting blood circulation; Panax notoginseng and small Rhododendron are the minister drugs for activating blood and dispelling wind; Radix Paeoniae Rubra and Allium macrostemon are the auxiliary drugs for clearing heat and cooling blood and for dredging yang and resolving stasis; and Glycyrrhiza uralensis is the ministerial drug for regulating all drugs. The traditional Chinese medicine preparation has the functions of tonifying qi, activating blood, dredging collaterals and relieving pain, and has the effects of improving blood circulation, regulating blood fat and preventing blood stasis, thereby providing important guiding significance for the treatment of coronary heart disease and the development of drugs.
Owner:LIUHE CHIMELONG PHARM CO LTD

Traditional Chinese medicine composition for relieving frequent ventricular premature beat

The invention relates to a traditional Chinese medicine composition for relieving frequent ventricular premature beat, which is prepared from the following medicinal materials in parts by weight: 3-10 parts of rhizoma pinellinae praeparata, 6-12 parts of bighead atractylodes rhizome, 3-10 parts of gastrodia elata, 3-15 parts of immature bitter orange, 5-10 parts of bamboo shavings, 6-10 parts of exocarpium, 3-6 parts of ginger, 3-9 parts of jujube, 6-12 parts of trichosanthes kirilowii maxim, 5-10 parts of allium macrostemon, 6-10 parts of inula flower, 6-10 parts of rhizoma nardostachyos and 5-10 parts of rhizoma acori graminei. , 3-6 parts of Chinese prickly ash, 6-15 parts of rhizoma cyperi, 6-15 parts of rhizoma polygonati and 6-12 parts of polygala tenuifolia. Based on the basic treatment principles of simultaneous regulation of liver and spleen, simultaneous treatment of phlegm and blood stasis and lifting and regulation, three methods of eliminating phlegm and dredging collaterals, soothing the liver and strengthening the spleen, and soothing the nerves and calming palpitation are combined, and the traditional Chinese medicine is designed aiming at the compound pathogenesis of liver depression and spleen deficiency-phlegm stagnation in heart collaterals, adopts pinellia ternate, bighead atractylodes rhizome and gastrodia elata decoction and trichosanthes kirilowii maxim and allium macrostemon decoction for addition and subtraction, and gives consideration to turbid phlegm and qi stagnation, so that the compatibility of cold and heat is more balanced; the accuracy and the safety of treating frequent ventricular premature beat are remarkably improved, and particularly, the method has outstanding advantages in the aspects of adapting to complex pathogenesis and reducing drug interaction risks.
Owner:THE SECOND AFFILIATED HOSPITAL OF JIANGXI UNIV OF TRADITIONAL CHINESE MEDICINE

Traditional Chinese medicine composition for treating cardiovascular diseases and preparation method thereof

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating cardiovascular diseases and a preparation method thereof.The traditional Chinese medicine composition comprises astragalus membranaceus, salvia miltiorrhiza, ligusticum wallichii, hawthorn, the root of kudzu vine, angelica sinensis, polygala tenuifolia, allium macrostemon, rhodiola rosea and euonymus alatus, and the preparation method comprises the steps that S1, medicinal materials are pretreated; s2, performing grouping extraction; s3, combining the extracting solutions; s4, purifying; and S5, drying. According to the scheme, winged euonymus twig is introduced, and the unique active ingredient dulcitrin contained in the winged euonymus twig can form a multi-dimensional synergistic system of tonifying qi, activating blood, activating yang and resisting oxidation with the medicinal materials such as astragalus membranaceus and salvia miltiorrhiza; experimental data show that the total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) of the traditional Chinese medicine composition containing the ramulus euonymi are obviously reduced, it is proved that the ramulus euonymi can enhance the synergistic effect of lowering lipid and improving hematorheology, and the problem that a traditional prescription is insufficient in regulating blood lipid strength is solved.
Owner:WEIFANG MEDICAL UNIV +1

American ginseng composite freeze-dried powder capable of prolonging life as well as preparation method and application of American ginseng composite freeze-dried powder

The invention belongs to the technical field of traditional Chinese medicines, and discloses American ginseng composite freeze-dried powder for prolonging life as well as a preparation method and application thereof. The composite freeze-dried powder comprises the following freeze-dried powder in parts by weight: 25-35 parts of American ginseng freeze-dried powder and 5-15 parts of sea-buckthorn freeze-dried powder which are mixed and fermented to obtain freeze-dried powder A, 15-25 parts of rhodiola rosea, 10-20 parts of freeze-dried powder B which is obtained by enzymolysis of pilose antler freeze-dried powder, 3-8 parts of dogwood, 2-5 parts of allium macrostemon, 1-3 parts of mint and 2-5 parts of lophatherum gracile. The effects of active ingredients are remarkably improved through enzymolysis and strain fermentation technologies, wherein American ginseng and sea-buckthorn are mixed according to the proportion and then are fermented through lactobacillus bulgaricus CICC 6047 and saccharomyces cerevisiae CICC1009 in sequence, and cornu cervi pantotrichum is subjected to enzymolysis through subtilisin. The composite freeze-dried powder has the effects of prolonging the life of nematodes and resisting oxidation; meanwhile, a mild bowel-relaxing effect is also shown, the bowel-relaxing powder can shorten the first defecation time of mice with constipation and increase the grain number and weight of excrement excreted by the mice, and the bowel-relaxing powder is particularly suitable for sub-health old people with long-term fatigue and constipation.
Owner:DONGFANG HONG PANAX QUINQUEFOLIUM PHARM (TONGHUA) CO LTD

Steroid saponin compound in longstalk allium macrostemon, preparation method of steroid saponin compound and application of steroid saponin compound in preparation of medicine for improving and / or treating myocardial infarction

The invention discloses steroid saponin compounds in longstalk allium macrostemon, a preparation method of the steroid saponin compounds and application of the steroid saponin compounds in preparation of medicines for improving and / or treating myocardial infarction. According to the invention, two compounds, i.e., long-stalk allium macrostemon saponin A and degalactotigonin, are separated from long-stalk allium macrostemon. In an MI mouse model, the two compounds can significantly improve heart function indexes (EF and FS), reduce myocardial infarction area, inhibit inflammatory infiltration and collagen deposition, and improve pathological injury; the levels of cTnI, LDH and CK-MB are reduced; the expression of inflammation related factors and proteins (caspase-1, ASC, GSDMD, IL-1beta and IL-18) can be inhibited. In-vitro experiments prove that the two compounds can effectively protect H9c2 myocardial cells damaged by oxygen-glucose deprivation. The two compounds can be used for preparing medicines for improving and / or treating myocardial infarction, and can be used for manufacturing chemical raw material medicines and preparations.
Owner:HEILONGJIANG UNIV OF CHINESE MEDICINE

A method for identifying different Allium macrostemon origins and genuine and counterfeit products in Allium macrostemon medicinal materials, including formulated granules, and its application.

This invention provides a method for identifying different Allium macrostemon origins and genuine and counterfeit Allium macrostemon products, including formulated granules, and its application. The identification method includes the following steps: (1) mixing the sample to be tested with a solvent to extract and obtain a test solution; (2) mixing a reference herb with a solvent to extract and obtain a reference herb solution; (3) performing thin-layer chromatography on the test solution and the reference herb solution, and determining the origin and / or authenticity of the sample to be tested based on the detection results; the Allium macrostemon origins include Allium macrostemon (garlic root) and Allium macrostemon (Allium chinense). The identification method provided by this invention can quickly and effectively identify Allium macrostemon (garlic root) and Allium macrostemon (Allium chinense), as well as the adulterants Allium macrostemon such as Scutellaria baicalensis and Ziziphus jujuba. The detection results are accurate, and the reagents used have low toxicity and high safety, which can minimize the possibility of the experimenter being exposed to toxic reagents.
Owner:BEIJING KANGRENTANG PHARMA

Traditional Chinese medicine preparation for treating coronary heart disease and preparation method thereof

The invention belongs to the technical field of traditional Chinese medicine preparations and particularly relates to a traditional Chinese medicine preparation for treating coronary heart disease and a preparation method thereof. The traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight: 22 to 28 parts of radix astragali seu hedysari, 20 to 25 parts of herba gerberae piloselloidis, 13 to 18 parts of radix notoginseng, 10 to 15 parts of herba ardisiae hypoglaucae, 8 to 13 parts of radix paeoniae rubra, 7 to 12 parts of bulbus allii macrostemi and 3 to 8 parts of radix glycyrrhizae. In the traditional Chinese medicine preparation, the astragalus membranaceus and the gerbera piloselloides are monarch drugs to tonify qi and activate blood; the radix notoginseng and the ardisia quinquegona are used as ministerial drugs for promoting blood circulation and dispelling wind; radix paeoniae rubra has the effects of clearing heat and cooling blood, and allium macrostemon has the effects of activating yang and removing stasis; and liquorice is used as a conductant drug for harmonizing the medicines. The traditional Chinese medicine formula disclosed by the invention is precise and appropriate in compatibility and synergistic in effect, has the effects of tonifying qi, activating blood and activating meridians to stop pain, also has the effects of improving blood circulation, regulating blood fat and preventing blood stasis, and provides important guiding significance for treatment of coronary heart disease and drug development.
Owner:LIUHE CHIMELONG PHARM CO LTD

Application of qi-regulating and blood-activating preparation in preparation of medicine for preventing or treating altitude stress

The invention relates to application of a qi-regulating and blood-activating preparation in a medicine for preventing or treating altitude stress, and belongs to the technical field of medicine application. The qi-regulating and blood-activating preparation is prepared by extracting and processing fructus cinnamoii, borneol, ligusticum wallichii and allium macrostemon. Experimental research shows that the qi-regulating and blood-activating preparation can effectively improve plateau hypoxia athletic ability and heart functions, can effectively improve plateau hypoxia lung tissue inflammation infiltration, reduces alveolar wall thickness, reduces lung tissue fibrosis, and reduces myocardial cell LDH release, thereby achieving the effect of effectively preventing and treating acute altitude stress.
Owner:GUIZHOU YIBAI PHARMA CO LTD

Method for constructing allium macrostemon medicinal material fingerprint spectrum and determining allium macrostemon index component content

The invention relates to a method for constructing an allium macrostemon medicinal material fingerprint spectrum and determining the content of allium macrostemon index components. The method comprises the following steps: preparing an allium macrostemon medicinal material into a test solution; injecting the test solution into a liquid chromatograph-mass spectrometer, obtaining the fingerprint spectrum of the allium macrostemon medicinal material according to the liquid chromatograph-mass spectrometer, and determining the content of the index components. According to the method for constructing the allium macrostemon medicinal material fingerprint spectrum and measuring the content, the evaluation standard of the allium macrostemon is comprehensively improved, and the clinical use effectiveness of the allium macrostemon medicinal material is ensured.
Owner:MACAU UNIV OF SCI & TECH

Application of qi-regulating and blood-activating preparation in preparation of medicine for preventing or treating heart failure

PendingCN121695220ACardiovascular disorderPlant ingredientsOxygen deprivationInflammatory lesion
The invention relates to application of a qi-regulating and blood-activating preparation in preparation of a medicine for preventing or treating heart failure, and belongs to the technical field of medicine application. The qi-regulating and blood-activating preparation is prepared from fructus cinnamoii, blumea balsamifera, ligusticum wallichii and allium macrostemon, and the preparation can be a dripping pill, a capsule, a tablet, a granule or a solution. Experiments show that the qi-regulating and blood-activating preparation can effectively treat heart failure, especially heart failure after myocardial infarction, and can reduce the infarction area of the heart, improve inflammatory lesion of the heart and improve myocardial fibrosis; the proliferation of myocardial cells induced by blood oxygen deprivation can be promoted, and the apoptosis of the myocardial cells can be improved. The use is convenient;
Owner:GUIZHOU YIBAI PHARMA CO LTD +1

Tripeptide substance capable of inhibiting staphylococcus aureus as well as preparation method and application of tripeptide substance

The invention belongs to the technical field of biology, discloses a tripeptide substance capable of inhibiting staphylococcus aureus and a preparation method, and particularly discloses an active peptide, and the amino acid sequence of the active peptide is KSK. The antibacterial active peptide provided by the invention has the activity of inhibiting staphylococcus aureus and does not have the activity of inhibiting escherichia coli, the antibacterial activity of the active peptide is influenced by the environmental pH, and the antibacterial effect is the best when the pH is 6.0. The active peptide can be synthesized by a common liquid-phase or solid-phase synthesis method, and can also be obtained by fermenting allium macrostemon pasture and then carrying out water extraction on the allium macrostemon pasture. Aiming at the antibacterial performance of the active peptide, the allium macrostemon can be used for fermenting forage grass to optimize intestinal flora of poultry (organic acids, such as lactic acid, acetic acid and propionic acid, capable of reducing pH are contained in the fermented forage grass), so that the intestinal tract of the poultry is healthier, the digestion and absorption functions can be improved, and a feasible scheme for replacing antibiotics is provided for the livestock and poultry industry.
Owner:SOUTH CHINA NORMAL UNIV +1

Method for cultivating unfertilized ovary of allium macrostemon bunge in vitro and application thereof

The application provides an in-vitro culture method for cultivating Allium fistulosum unpollinated ovary and application thereof, and belongs to the technical field of plant tissue culture.The method comprises the following steps: taking the intact ovary of Allium fistulosum which is not pollinated as an explant, and performing induction culture, proliferation culture and rooting culture.Through the culture of the intact ovary and the one-step induction differentiation method, the method is simple, the induction rate is high, the operability is strong, a large number of Allium fistulosum unpollinated ovary culture regenerated plants can be obtained, and breeding materials which can be applied to the selection and breeding of different Allium fistulosum types are screened out, compared with the traditional breeding method, the breeding period is greatly shortened.
Owner:GUIZHOU HORTICULTURAL INST (GUIZHOU HORTICULTURAL ENG TECH RES CENT)

Traditional Chinese medicine composition for preventing and treating myocardial ischemia reperfusion injury, preparation and preparation method

The invention relates to the technical field of traditional Chinese medicine preparation, in particular to a traditional Chinese medicine composition for preventing and treating myocardial ischemia reperfusion injury, a preparation and a preparation method. The traditional Chinese medicine composition is prepared from the following raw medicinal materials in parts by weight: 15-25 parts of radix salviae miltiorrhizae, 15-25 parts of radix astragali, 10-15 parts of ground beetles, 10-15 parts of cornu bubali, 10-20 parts of poria cocos, 10-20 parts of semen plantaginis, 10-15 parts of honeysuckle stems, 10-20 parts of radix polygonati officinalis, 10-20 parts of radix asparagi, 10-15 parts of herba asari, 10-20 parts of gypsum, 10-20 parts of rhizoma anemarrhenae, 10-15 parts of allium macrostemon, 10-15 parts of geranium wilfordii and 10-15 parts of silybum marianum seeds. The preparation method comprises the following steps: weighing the traditional Chinese medicine composition according to the formula dosage, and then adding water for decoction to obtain a traditional Chinese medicine decoction; combining the traditional Chinese medicine decoction, filtering and concentrating to obtain traditional Chinese medicine extract; and adding auxiliary materials into the traditional Chinese medicine extract, and preparing by adopting a conventional preparation mode. Combined use of monarch, minister, assistant and guide drugs can fully relieve myocardial ischemia reperfusion injury.
Owner:HEILONGJIANG UNIV OF CHINESE MEDICINE

Fragrant fermented ginseng solid beverage, byproduct ginseng tablet candy and production process

The invention discloses a fragrant fermented ginseng solid beverage, a byproduct ginseng tablet candy and a production process. The fragrant fermented ginseng solid beverage comprises the following raw materials: ginseng, codonopsis pilosula, astragalus membranaceus, radix puerariae, gastrodia elata, gordon euryale seeds, hawthorn, fingered citron, sea-buckthorn, malt, cistanche, peach kernels, mulberries, bunge cherry seeds, almonds, fructus cannabis, angelica sinensis, radix ophiopogonis, asparagus fern, semen cassiae, radix polygonati officinalis, liquorice, oysters, intelligent kernels, dogwood, spina date seeds, lophatherum gracile, radix angelicae, ginkgo, white hyacinth beans, lily, chrysanthemum, momordica grosvenori, poria cocos, mulberry leaves and platycodon grandiflorum. And lotus seeds, allium macrostemon, coix seeds, honey and a fermentation auxiliary agent. The technology of low-temperature activity preservation, fermentation flavor regulation and control, full-ingredient utilization and the like is integrated in a breakthrough mode, the product has the advantages that the ginsenoside retention rate is larger than or equal to 92%, the disintegration time is smaller than or equal to 4 min, the bitter taste covering degree is excellent and the like, and the industrial problems that a traditional ginseng product is large in activity loss, poor in taste, difficult to take and throat and the like are solved.
Owner:FUJIAN TIANWU FOOD TECHNOLOGY CO LTD