38 results about "Allium macrostemon" patented technology

The invention discloses a traditional Chinese medicine composition for preventing and treating atherosclerosis and plaque formation and application thereof. The traditional Chinese medicine composition comprises the following traditional Chinese medicine components in parts by weight: 10-15 parts of peach kernel, 7-12 parts of safflower, 12-18 parts of angelica sinensis, 15-25 parts of radix rehmanniae, 12-18 parts of ligusticum wallichii, 10-15 parts of radix paeoniae rubra, 12-18 parts of radix cyathulae, 12-18 parts of platycodon grandiflorum, 12-18 parts of radix bupleuri, 10-15 parts of bran-fried fructus aurantii, 4-8 parts of honey-fried licorice root, 10-15 parts of ginseng, 8-12 parts of poria cocos, 4-8 parts of rhizoma zingiberis, 10-15 parts of rhizoma cyperi, 12-18 parts of radix curcumae, 10-15 parts of cortex albiziae, 12-18 parts of rhizoma pinelliae preparata, 12-18 parts of exocarpium citri grandis, 20-30 parts of 25 parts of allium macrostemon, 25-35 parts of corn stigma, 15-25 parts of plantain herb and 25-35 parts of oyster; based on the theory of traditional Chinese medicine, all traditional Chinese medicine raw materials are screened, and through the combined action of all the raw materials, the traditional Chinese medicine composition has a remarkable curative effect on atherosclerosis and takes effect quickly.

This invention discloses a traditional Chinese medicine composition for improving hypertension, belonging to the field of traditional Chinese medicine compound preparation technology. This invention targets the core pathogenesis of hypertension caused by phlegm-dampness obstruction and peripheral microcirculation disorders, leading to abnormal activation of the hypothalamic-sympathetic-cardiac axis and compensatory cardiac hypertensive. The treatment principle is to resolve phlegm and dampness, and invigorate blood circulation. It is formulated with nutmeg, allium macrostemon, amomum villosum, peach kernel, safflower, platycodon grandiflorus, angelica dahurica, and tangerine peel. This combination can dredge the meridians, improve peripheral blood supply, and alleviate cardiac compensatory pumping, thus addressing hypertension caused by phlegm-dampness obstruction at its root. The formula is scientifically formulated, highly safe, and easy to prepare, making it suitable for long-term treatment and industrial promotion.

The invention discloses a medicine for treating the heart of a human body, and particularly relates to the field of medicines, the medicine is prepared from the following components in percentage by mass: 13.8% of radix salviae miltiorrhizae, 4.1% of allium macrostemon, 8.3% of semen trichosanthis, 2% of polygala tenuifolia, 8.3% of radix ophiopogonis, 2% of sandalwood, 6.9% of pericarpium citri reticulatae viride, 13.8% of lily, 8.3% of semen boitae, 10.4% of poria cocos, 8.3% of oriental cherry powder and 13.8% of earthworm, and the sum of the mass percentages of the components is 100%. According to the medicine for treating the heart of the human body, traditional Chinese medicine decoction pieces such as salvia miltiorrhiza, allium macrostemon, snakegourd seeds, polygala tenuifolia, radix ophiopogonis, sandalwood, pericarpium citri reticulatae viride, lily, platycladi seeds, poria cocos, oriental cherry powder and lumbricus are crushed and proportioned according to corresponding formula proportions and processes, so that the medicine plays the maximum effects of all the decoction pieces, is easier to take and absorb, and can be taken for a long time after being taken. The traditional Chinese medicine composition has obvious treatment effects on cardiac insufficiency, dyspnea, weakness, fatigue, angina pectoris, palpitation, palpitation and other problems caused by heart problems of heart disease patients, and can effectively treat coronary heart disease, myocardial ischemia, arrhythmia and other heart diseases.

This invention provides a traditional Chinese medicine compound for treating viral myocarditis, belonging to the field of traditional Chinese medicine pharmaceutical technology. The compound consists of Forsythia suspensa, Fagopyrum dibotrys, Pseudostellaria heterophylla, Rhodiola rosea, Citrus medica, Allium macrostemon, Poria cocos, Gynostemma pentaphyllum, Salvia miltiorrhiza, Dalbergia odorifera, Cynanchum paniculatum, and Valeriana. This traditional Chinese medicine compound exhibits significant protective effects against viral myocarditis, specifically by significantly reducing damage to H9c2 cardiomyocytes caused by CVB3 virus. Its mechanism of action is closely related to downregulating the expression of inflammatory factors TNF-α and IL-6 and inhibiting the inflammatory response. Simultaneously, within the experimental concentration range, the compound shows no toxicity to cardiomyocytes, demonstrating good biocompatibility. Furthermore, this compound can significantly reduce myocardial tissue damage in a viral myocarditis model mouse by inhibiting the in vivo inflammatory response and regulating oxidative stress imbalance, providing a safe and effective new treatment option for the clinical treatment of viral myocarditis.

The invention relates to granules for promoting blood circulation to remove meridian obstruction and a preparation method thereof. Ginkgo leaves, fried spina date seeds, astragalus membranaceus, radix puerariae, hawthorn, salvia miltiorrhiza, allium macrostemon, rhodiola rosea, fructus lycii, acanthopanax, schisandra chinensis and radix ophiopogonis are selected as raw materials, the raw materials are decocted, filtered, concentrated and granulated, the materials are all selected from natural traditional Chinese medicine components, the effects of promoting blood circulation to remove blood stasis and activating meridians to stop pain are achieved, and the traditional Chinese medicine composition has a remarkable curative effect on chest stuffiness, cardiodynia, dizziness, coronary heart disease and angina pectoris caused by blood stasis blocking collaterals. The traditional Chinese medicine composition has obvious curative effects on symptoms such as hypertension, hyperlipidemia and cerebral arteriosclerosis, has no side effect on the body, is simple in preparation method and low in production cost, and has application and popularization prospects.

The embodiment of the invention discloses Chinese herbal medicine freckle-removing cream and a preparation method thereof. The Chinese herbal medicine freckle-removing cream is prepared from Chinese herbal medicine decoction liquor and a natural oil-in-water emulsion system, and the Chinese herbal medicine decoction liquor comprises the following medicinal materials: rehmannia, radix polygonati officinalis, Chinese waxgourd seed, stiff silkworm, caltrop, hawthorn, hairyvein agrimony, allium macrostemon, vine of multiflower knotweed, cortex albiziae, platycladi seed, lalang grass rhizome, perilla leaf, pepper and magnolia bark; the natural oil-in-water emulsifying system comprises the following raw materials: olive oil emulsifying wax, shea butter, jojoba oil, grape seed oil and vitamin E. Human body trials prove that the Chinese herbal medicine freckle-removing cream is fine and moist in skin feeling and not greasy after being smeared, and skin irritation reactions such as stabbing pain, redness and pruritus do not exist in the using process; after continuous use for 3 months, chloasma, sunburn and other color spots are obviously faded, the skin glossiness and fineness are obviously improved, and no obvious rebound occurs after the use is stopped; the composition is suitable for dry, oily, mixed and sensitive skin, and has good safety and tolerance.

This invention discloses a warming and dispersing medicinal and edible composition and its preparation method. This invention relates to the field of traditional Chinese medicine health food technology. The active ingredients of the composition are extracted from the following medicinal and edible materials: 3-10 parts by weight of dried ginger, 2-8 parts by weight of cinnamon, 5-15 parts by weight of Allium macrostemon, and 10-30 parts by weight of Astragalus membranaceus. Small molecule extract particles are prepared through processes such as β-cyclodextrin inclusion and wet granulation, significantly improving the dissolution rate and bioavailability of the active ingredients. The product is also convenient to prepare, easy to carry, and suitable for long-term use. In terms of safety, all raw materials are medicinal and edible substances. Clinical trials have proven that the overall effective rate for symptoms of Yang deficiency such as aversion to cold, cold limbs, lethargy, and loose stools is over 94%, with no obvious toxic side effects. It can be safely used for daily health maintenance and auxiliary conditioning of those with Yang deficiency and cold constitution. Pure coconut powder is used as a flavoring material, resulting in a rich aroma and good taste.

The present application mainly relates to the separation and identification and application of active ingredients in traditional Chinese medicine, and specifically discloses a separation and purification of a steroidal saponin compound in Allii Macrostemonis Bulbus. According to the physical and chemical properties and high-resolution electrospray mass spectrometry (HR-ESI-MS), one-dimensional / two-dimensional nuclear magnetic resonance spectroscopy (1D- / 2D-NMR) and other spectral technologies, the structure of the compound is identified, the structure is analyzed and the molecular formula is determined, and finally named as Allii Macrostemonis Bulbus saponin U. The pharmacological activity of Allii Macrostemonis Bulbus saponin U is studied through in vitro cell experiments, and it is found that Allii Macrostemonis Bulbus saponin U significantly improves the cell viability of mouse hippocampal neurons after glutamate treatment, has good neuroprotective activity, and can be used for the preparation and application of anti-nerve injury drugs.

The invention relates to the technical field of pharmaceutical preparations, in particular to a traditional Chinese medicine compound and preparation for treating coronary heart disease and a preparation method and application of the traditional Chinese medicine compound and preparation. The traditional Chinese medicine composition is prepared from the following medicinal materials in parts by weight: 10-30 parts of astragalus membranaceus, 5-15 parts of rhodiola rosea, 10-30 parts of salvia miltiorrhiza, 5-15 parts of ligusticum wallichii, 10-30 parts of trichosanthes kirilowii maxim, 5-15 parts of allium macrostemon, 5-15 parts of folium ginkgo, 10-30 parts of radix puerariae, 10-30 parts of radix ophiopogonis, 3-10 parts of schisandra chinensis, 15-30 parts of oyster, 5-15 parts of cassia twig and 3-10 parts of liquorice. Animal experiment results show that the traditional Chinese medicine composition provided by the invention has remarkable and multi-aspect curative effect advantages in the aspect of treating a coronary heart disease rat model. The traditional Chinese medicine composition not only can enhance myocardial contractility and recover heart blood pumping function, but also can inhibit inflammatory response, relieve myocardial damage, effectively relieve myocardial structure damage and protect myocardial tissue integrity. In addition, a proportional experiment result shows that the effect of the composition provided by the invention can be obviously weakened by losing any medicine pair, so that all the medicines in the formula cannot be absent.

This invention discloses a traditional Chinese medicine composition for treating ulcerative colitis, its preparation method, combined drugs, and applications. The traditional Chinese medicine composition for treating ulcerative colitis of this invention is made from the following raw materials in parts by weight: Astragalus membranaceus 13-26 parts, Lonicera japonica 10-20 parts, Sargentodoxa cuneata 10-20 parts, Prunus mume 8-16 parts, Agrimonia pilosa 8-16 parts, Allium macrostemon 6-12 parts, Platycodon grandiflorus 6-12 parts, Coptis chinensis 3-6 parts, and Panax notoginseng powder 1-3 parts. An animal model of ulcerative colitis was constructed using DSS induction, and the results showed that the traditional Chinese medicine composition of this invention has a certain therapeutic effect on ulcerative colitis. Clinical studies showed that the traditional Chinese medicine composition of this invention, used in combination with mesalazine enteric-coated tablets, can reduce the modified Mayo score and serum inflammatory markers in patients with active ulcerative colitis, improve colonic mucosal inflammation and gastrointestinal symptoms, and effectively treat active ulcerative colitis of the damp-heat type.

The present application belongs to the technical field of traditional Chinese medicine preparation, and particularly relates to a traditional Chinese medicine preparation for treating coronary heart disease and a preparation method thereof. The traditional Chinese medicine preparation comprises the following raw materials in parts by weight: 22-28 parts of Astragalus membranaceus, 20-25 parts of Prenanthes altissima, 13-18 parts of Panax notoginseng, 10-15 parts of small Rhododendron, 8-13 parts of Radix Paeoniae Rubra, 7-12 parts of Allium macrostemon, and 3-8 parts of Glycyrrhiza uralensis. In the traditional Chinese medicine preparation, Astragalus membranaceus and Prenanthes altissima are the monarch drugs for tonifying qi and promoting blood circulation; Panax notoginseng and small Rhododendron are the minister drugs for activating blood and dispelling wind; Radix Paeoniae Rubra and Allium macrostemon are the auxiliary drugs for clearing heat and cooling blood and for dredging yang and resolving stasis; and Glycyrrhiza uralensis is the ministerial drug for regulating all drugs. The traditional Chinese medicine preparation has the functions of tonifying qi, activating blood, dredging collaterals and relieving pain, and has the effects of improving blood circulation, regulating blood fat and preventing blood stasis, thereby providing important guiding significance for the treatment of coronary heart disease and the development of drugs.

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating cardiovascular diseases and a preparation method thereof.The traditional Chinese medicine composition comprises astragalus membranaceus, salvia miltiorrhiza, ligusticum wallichii, hawthorn, the root of kudzu vine, angelica sinensis, polygala tenuifolia, allium macrostemon, rhodiola rosea and euonymus alatus, and the preparation method comprises the steps that S1, medicinal materials are pretreated; s2, performing grouping extraction; s3, combining the extracting solutions; s4, purifying; and S5, drying. According to the scheme, winged euonymus twig is introduced, and the unique active ingredient dulcitrin contained in the winged euonymus twig can form a multi-dimensional synergistic system of tonifying qi, activating blood, activating yang and resisting oxidation with the medicinal materials such as astragalus membranaceus and salvia miltiorrhiza; experimental data show that the total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) of the traditional Chinese medicine composition containing the ramulus euonymi are obviously reduced, it is proved that the ramulus euonymi can enhance the synergistic effect of lowering lipid and improving hematorheology, and the problem that a traditional prescription is insufficient in regulating blood lipid strength is solved.

The invention belongs to the technical field of traditional Chinese medicines, and discloses American ginseng composite freeze-dried powder for prolonging life as well as a preparation method and application thereof. The composite freeze-dried powder comprises the following freeze-dried powder in parts by weight: 25-35 parts of American ginseng freeze-dried powder and 5-15 parts of sea-buckthorn freeze-dried powder which are mixed and fermented to obtain freeze-dried powder A, 15-25 parts of rhodiola rosea, 10-20 parts of freeze-dried powder B which is obtained by enzymolysis of pilose antler freeze-dried powder, 3-8 parts of dogwood, 2-5 parts of allium macrostemon, 1-3 parts of mint and 2-5 parts of lophatherum gracile. The effects of active ingredients are remarkably improved through enzymolysis and strain fermentation technologies, wherein American ginseng and sea-buckthorn are mixed according to the proportion and then are fermented through lactobacillus bulgaricus CICC 6047 and saccharomyces cerevisiae CICC1009 in sequence, and cornu cervi pantotrichum is subjected to enzymolysis through subtilisin. The composite freeze-dried powder has the effects of prolonging the life of nematodes and resisting oxidation; meanwhile, a mild bowel-relaxing effect is also shown, the bowel-relaxing powder can shorten the first defecation time of mice with constipation and increase the grain number and weight of excrement excreted by the mice, and the bowel-relaxing powder is particularly suitable for sub-health old people with long-term fatigue and constipation.

The invention discloses steroid saponin compounds in longstalk allium macrostemon, a preparation method of the steroid saponin compounds and application of the steroid saponin compounds in preparation of medicines for improving and / or treating myocardial infarction. According to the invention, two compounds, i.e., long-stalk allium macrostemon saponin A and degalactotigonin, are separated from long-stalk allium macrostemon. In an MI mouse model, the two compounds can significantly improve heart function indexes (EF and FS), reduce myocardial infarction area, inhibit inflammatory infiltration and collagen deposition, and improve pathological injury; the levels of cTnI, LDH and CK-MB are reduced; the expression of inflammation related factors and proteins (caspase-1, ASC, GSDMD, IL-1beta and IL-18) can be inhibited. In-vitro experiments prove that the two compounds can effectively protect H9c2 myocardial cells damaged by oxygen-glucose deprivation. The two compounds can be used for preparing medicines for improving and / or treating myocardial infarction, and can be used for manufacturing chemical raw material medicines and preparations.

This invention provides a method for identifying different Allium macrostemon origins and genuine and counterfeit Allium macrostemon products, including formulated granules, and its application. The identification method includes the following steps: (1) mixing the sample to be tested with a solvent to extract and obtain a test solution; (2) mixing a reference herb with a solvent to extract and obtain a reference herb solution; (3) performing thin-layer chromatography on the test solution and the reference herb solution, and determining the origin and / or authenticity of the sample to be tested based on the detection results; the Allium macrostemon origins include Allium macrostemon (garlic root) and Allium macrostemon (Allium chinense). The identification method provided by this invention can quickly and effectively identify Allium macrostemon (garlic root) and Allium macrostemon (Allium chinense), as well as the adulterants Allium macrostemon such as Scutellaria baicalensis and Ziziphus jujuba. The detection results are accurate, and the reagents used have low toxicity and high safety, which can minimize the possibility of the experimenter being exposed to toxic reagents.

The invention belongs to the technical field of traditional Chinese medicine preparations and particularly relates to a traditional Chinese medicine preparation for treating coronary heart disease and a preparation method thereof. The traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight: 22 to 28 parts of radix astragali seu hedysari, 20 to 25 parts of herba gerberae piloselloidis, 13 to 18 parts of radix notoginseng, 10 to 15 parts of herba ardisiae hypoglaucae, 8 to 13 parts of radix paeoniae rubra, 7 to 12 parts of bulbus allii macrostemi and 3 to 8 parts of radix glycyrrhizae. In the traditional Chinese medicine preparation, the astragalus membranaceus and the gerbera piloselloides are monarch drugs to tonify qi and activate blood; the radix notoginseng and the ardisia quinquegona are used as ministerial drugs for promoting blood circulation and dispelling wind; radix paeoniae rubra has the effects of clearing heat and cooling blood, and allium macrostemon has the effects of activating yang and removing stasis; and liquorice is used as a conductant drug for harmonizing the medicines. The traditional Chinese medicine formula disclosed by the invention is precise and appropriate in compatibility and synergistic in effect, has the effects of tonifying qi, activating blood and activating meridians to stop pain, also has the effects of improving blood circulation, regulating blood fat and preventing blood stasis, and provides important guiding significance for treatment of coronary heart disease and drug development.

The invention relates to application of a qi-regulating and blood-activating preparation in a medicine for preventing or treating altitude stress, and belongs to the technical field of medicine application. The qi-regulating and blood-activating preparation is prepared by extracting and processing fructus cinnamoii, borneol, ligusticum wallichii and allium macrostemon. Experimental research shows that the qi-regulating and blood-activating preparation can effectively improve plateau hypoxia athletic ability and heart functions, can effectively improve plateau hypoxia lung tissue inflammation infiltration, reduces alveolar wall thickness, reduces lung tissue fibrosis, and reduces myocardial cell LDH release, thereby achieving the effect of effectively preventing and treating acute altitude stress.

The invention relates to application of a qi-regulating and blood-activating preparation in preparation of a medicine for preventing or treating heart failure, and belongs to the technical field of medicine application. The qi-regulating and blood-activating preparation is prepared from fructus cinnamoii, blumea balsamifera, ligusticum wallichii and allium macrostemon, and the preparation can be a dripping pill, a capsule, a tablet, a granule or a solution. Experiments show that the qi-regulating and blood-activating preparation can effectively treat heart failure, especially heart failure after myocardial infarction, and can reduce the infarction area of the heart, improve inflammatory lesion of the heart and improve myocardial fibrosis; the proliferation of myocardial cells induced by blood oxygen deprivation can be promoted, and the apoptosis of the myocardial cells can be improved. The use is convenient;

The invention belongs to the technical field of biology, discloses a tripeptide substance capable of inhibiting staphylococcus aureus and a preparation method, and particularly discloses an active peptide, and the amino acid sequence of the active peptide is KSK. The antibacterial active peptide provided by the invention has the activity of inhibiting staphylococcus aureus and does not have the activity of inhibiting escherichia coli, the antibacterial activity of the active peptide is influenced by the environmental pH, and the antibacterial effect is the best when the pH is 6.0. The active peptide can be synthesized by a common liquid-phase or solid-phase synthesis method, and can also be obtained by fermenting allium macrostemon pasture and then carrying out water extraction on the allium macrostemon pasture. Aiming at the antibacterial performance of the active peptide, the allium macrostemon can be used for fermenting forage grass to optimize intestinal flora of poultry (organic acids, such as lactic acid, acetic acid and propionic acid, capable of reducing pH are contained in the fermented forage grass), so that the intestinal tract of the poultry is healthier, the digestion and absorption functions can be improved, and a feasible scheme for replacing antibiotics is provided for the livestock and poultry industry.

The application provides an in-vitro culture method for cultivating Allium fistulosum unpollinated ovary and application thereof, and belongs to the technical field of plant tissue culture.The method comprises the following steps: taking the intact ovary of Allium fistulosum which is not pollinated as an explant, and performing induction culture, proliferation culture and rooting culture.Through the culture of the intact ovary and the one-step induction differentiation method, the method is simple, the induction rate is high, the operability is strong, a large number of Allium fistulosum unpollinated ovary culture regenerated plants can be obtained, and breeding materials which can be applied to the selection and breeding of different Allium fistulosum types are screened out, compared with the traditional breeding method, the breeding period is greatly shortened.

The invention relates to the technical field of animal breeding, in particular to an under-forest antibiotic-free native chicken breeding method based on precise regulation and control of food and medicine homologous components, which comprises the following steps: selecting a broad-leaf mixed forest with the slope of less than or equal to 15 degrees, the pH value of 6.0-7.5, the organic matter of more than or equal to 1.5% and the annual sunshine of more than or equal to 1200 hours, dividing the broad-leaf mixed forest into three equal-area partitions, arranging a preservative bamboo isolation fence, and sowing allium macrostemon and houttuynia cordata, and performing sunshade net maintenance for 22 + / -3 days until the seedling height reaches the standard, and then performing rotation grazing and stocking. The method comprises the following steps: carrying out plant extract disinfection every day, carrying out padding micro-ecological fermentation treatment and carrying out hermetia illucens resource utilization. And the vegetation regeneration rate in the pasturing period is greater than or equal to 85%. The sick and weak chickens are fed with allium macrostemon-herba houttuyniae juice, the incidence rate of intestinal diseases is remarkably reduced, the technical pain point of traditional under-forest breeding is solved, meanwhile, a raw material replacement scheme, climate adaptation parameters and the variety adaptation range are expanded, and unification of ecological benefits, economic benefits and social benefits is achieved.

The invention relates to the technical field of traditional Chinese medicines, and provides a traditional Chinese medicine composition capable of reducing blood fat and eliminating carotid plaques. Comprising the following components in parts by weight: 15-20 parts of radix puerariae, 3-6 parts of natto powder, 8-10 parts of red yeast rice, 2-4 parts of allium macrostemon, 2-4 parts of earthworm protein, 5-8 parts of peach kernels, 2-6 parts of perilla seeds, 1-2 parts of soybean peptide powder, 12-15 parts of a grape seed extract, 8-10 parts of a celery seed extract, 1-2 parts of selenium-enriched triticale peptide, 2-3 parts of saffron and 2-4 parts of turmeric. According to the technical scheme, the problem that a traditional Chinese medicine composition in the related technology is poor in blood fat reducing effect is solved.

The invention provides a preparation process and a quality evaluation method of trichosanthes kirilowii maxim, allium macrostemon and pinellia ternate decoction formula granules, and relates to the technical field of medicine preparation and quality detection. The preparation process of the snakegourd fruit, allium macrostemon and pinellia ternate decoction formula granules comprises the following steps: S1, crushing snakegourd fruit, allium macrostemon and pinellia ternate to obtain a mixed medicinal material, soaking the mixed medicinal material in a solvent, decocting, refluxing and concentrating to obtain a fluid extract; s2, mixing and drying the fluid extract and auxiliary materials to obtain extract powder; s3, mixing the extract powder, auxiliary materials and a wetting agent to obtain a soft material, granulating and drying to obtain the snakegourd fruit, allium macrostemon and pinellia ternate decoction formula granules. The quality evaluation method comprises a thin-layer identification method, a fingerprint spectrum method and a content detection method. The invention provides an optimal preparation process of the trichosanthes kirilowii Maxim, allium macrostemon and pinellia ternate decoction formula granules, establishes a quality standard of the trichosanthes kirilowii Maxim, allium macrostemon and pinellia ternate decoction formula granules, and has great significance for large-scale popularization and clinical use specifications of the trichosanthes kirilowii Maxim, allium macrostemon and pinellia ternate decoction formula granules

The invention discloses a traditional Chinese medicine for tonifying qi, activating yang, detoxifying and preventing and treating atherosclerosis, which can effectively solve the medication problem of preventing and treating atherosclerosis The traditional Chinese medicine preparation is prepared from the following traditional Chinese medicine raw materials: allium macrostemon, radix puerariae, astragalus membranaceus, Chinese yam, scutellaria baicalensis and Chinese hibiscus root. The preparation method comprises the following steps: crushing the allium macrostemon, the radix puerariae, the astragalus membranaceus, the Chinese yam, the scutellaria baicalensis and the Chinese hibiscus root; adding water for presoaking, adding cellulase and pectinase for enzymolysis, and heating for inactivation; decocting the enzymatic hydrolysate twice, combining extracting solutions, performing rough filtration, and performing vacuum concentration; adding ethanol, standing, carrying out alcohol precipitation separation, filtering supernate, and concentrating; and drying and collecting powder to obtain a finished product. The preparation method is simple, the raw materials are rich, the preparation method is easy to operate and easy for industrial production, a four-step method of water extraction, enzymolysis assistance, alcohol precipitation and spray drying is adopted in the preparation process, active ingredients such as polysaccharides, flavones and saponins in the medicinal materials can be reserved to the maximum extent, and the characteristics of stability and convenience in storage of the preparation are realized through a modern process. The traditional Chinese medicine composition is an innovation in prevention and treatment of atherosclerosis and has practical popularization and application values.

The invention discloses a traditional Chinese medicine composition for soothing liver, regulating qi, activating yang and removing stasis. The traditional Chinese medicine composition is prepared from, by weight, 15-30 parts of radix bupleuri, 20-40 parts of trichosanthes kirilowii maxim, 15-30 parts of immature bitter orange, 15-25 parts of allium macrostemon and 15-35 parts of ginger. On the basis of deep analysis of complex pathogenesis of liver depression and phlegm stagnation, chest yang deficiency and spleen dysfunction, the invention provides the traditional Chinese medicine composition with the core treatment rule of soothing liver and regulating qi, activating yang and removing stasis and tonifying spleen and reducing phlegm, and the Chinese thorowax root is used as the monarch material to soothe liver and relieve depression and regulate qi activity; trichosanthes kirilowii maxim and immature bitter orange are used as ministerial drugs for relieving chest stuffiness, reducing phlegm, allium macrostemon is used as an assistant to activate yang and remove stasis; the ginger is used as a guide to warm middle and harmonize stomach and harmonize drug properties. The medicines cooperate to form the compatibility characteristics of soothing liver without hurting yin, reducing phlegm without helping cold, activating yang without consuming qi and tonifying spleen without nourishing greasy feeling, and the traditional Chinese medicine composition is especially suitable for complicated syndromes of phlegm, qi and deficiency mingling.

This invention provides a pharmaceutical composition for improving hyperlipidemia, comprising total alkaloids from Trichosanthes kirilowii and total saponins from Allium macrostemon. The present invention applies the combination of total alkaloids from Trichosanthes kirilowii and total saponins from Allium macrostemon to treat hyperlipidemia. In vivo models demonstrate that the total alkaloids from Trichosanthes kirilowii and total saponins from Allium macrostemon of this invention have a synergistic effect in treating hyperlipidemia.

This invention provides a highly effective, broad-spectrum antibacterial, and rapidly repairing traditional Chinese medicine preparation for the treatment of skin and mucous membrane infections. It is formulated from a combination of herbs including snow lotus, buffalo horn, allium macrostemon, poria cocos, reed rhizome, dictamnus dasycarpus bark, Paris polyphylla, chrysanthemum, scutellaria barbata, physalis alkekengi, mulberry bark, and honeysuckle, based on traditional Chinese medicine theory, combined with modern medical research and clinical experience. The selected herbs are pure Chinese herbal medicines with a rational synergistic combination. Applied externally, the medicine acts directly on the affected area, resulting in rapid action. It avoids the gastrointestinal, hepatic, and renal irritation associated with oral preparations, reducing patient discomfort. The treatment course is short, the cost is low, and it is convenient to use. Clinical symptoms disappear rapidly, the efficacy is significant, and it is practical, safe, and free of toxic side effects.

This invention utilizes *Allium macrostemon* to obtain its aqueous extract, petroleum ether extract, dichloromethane extract, ethyl acetate extract, and n-butanol extract. The effects of these aqueous extracts and extracts of different polarities on the learning and memory functions of D-galactose-induced aging model mice were investigated using Y-maze, darkness avoidance, Morris water maze, and laser speckle cerebral blood flow assays. Reactive oxygen species (ROS), SOD, and MDA were also measured. Multiple experiments demonstrated that *Allium macrostemon* can improve memory function in mice. Furthermore, the effects of *Allium macrostemon* extract on arecoline- or oxidative tremor-induced tremor behavior in mice were studied. The results showed that *Allium macrostemon* extract can effectively shorten the duration of tremors, proposing a new application for *Allium macrostemon* extract in the preparation of drugs for the prevention and / or treatment of neurodegenerative diseases, providing broad application prospects for the treatment or adjuvant therapy of neurodegenerative diseases.

The invention relates to a carbon quantum dot prepared by taking a traditional Chinese medicine allium macrostemon as a carbon source and an application of the carbon quantum dot in cisplatin-induced acute kidney injury, and can effectively solve the problems of insufficient pertinence of existing support treatment and limitation of lack of effective long-term intervention means. The obtained CQDs can be used for in-vivo intervention to reduce the levels of renal injury markers and proinflammatory factors in an AKI state and inhibit phosphorylation activation of a JNK and NF-kappa B related pathway, so that cisplatin-induced renal tissue injury is relieved; meanwhile, the mitochondrial damage expression is improved on the ultrastructure level, and a certain protection effect is achieved on related glomerular structures.

The invention discloses a traditional Chinese medicine polysaccharide with lipid-lowering activity and a preparation method and application thereof, and relates to the technical field of biological medicine, the traditional Chinese medicine polysaccharide is allium macrostemon neutral homogeneous polysaccharide ACP1, the weight-average molecular weight is 17.96 kDa, the polydispersity index is 1.726, and the traditional Chinese medicine polysaccharide is composed of glucose and fructose according to the molar ratio of 2.53%: 97.47%. The allium macrostemon neutral homogeneous polysaccharide provided by the invention is a new neutral homogeneous polysaccharide ACP1 extracted from allium macrostemon, can effectively improve oleic acid-induced AML-12 cell lipid deposition, and has remarkable lipid-lowering activity and high safety. The preparation method of the allium macrostemon neutral homogeneous polysaccharide is good in repeatability, the obtained neutral homogeneous polysaccharide is high in purity, and industrial production is facilitated.