Granules for promoting blood circulation to remove meridian obstruction and preparation method thereof

Abstract

The invention relates to granules for promoting blood circulation to remove meridian obstruction and a preparation method thereof. Ginkgo leaves, fried spina date seeds, astragalus membranaceus, radix puerariae, hawthorn, salvia miltiorrhiza, allium macrostemon, rhodiola rosea, fructus lycii, acanthopanax, schisandra chinensis and radix ophiopogonis are selected as raw materials, the raw materials are decocted, filtered, concentrated and granulated, the materials are all selected from natural traditional Chinese medicine components, the effects of promoting blood circulation to remove blood stasis and activating meridians to stop pain are achieved, and the traditional Chinese medicine composition has a remarkable curative effect on chest stuffiness, cardiodynia, dizziness, coronary heart disease and angina pectoris caused by blood stasis blocking collaterals. The traditional Chinese medicine composition has obvious curative effects on symptoms such as hypertension, hyperlipidemia and cerebral arteriosclerosis, has no side effect on the body, is simple in preparation method and low in production cost, and has application and popularization prospects.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine, in particular to a blood-activating and collateral-unblocking granule and a preparation method thereof. Background Art

[0002] With rapid urbanization in my country, the pace of life is accelerating. This is especially true for office workers who spend long hours at their desks, often working overtime, experiencing irregular work and rest schedules, lack of exercise, and an unhealthy diet. This can lead to blood stasis and blocked meridians. Elderly individuals often experience dizziness, chest tightness, palpitations, shortness of breath, coronary heart disease, hypertension, and cerebral infarction. Hypertension, high cholesterol, and high blood viscosity are common conditions in middle-aged and elderly men. Clinically, elevated blood pressure, cholesterol, or viscosity are the primary manifestations, with symptoms such as headaches, dizziness, chest tightness, and back pain. Currently, a wide range of medications are used to treat hypertension, high cholesterol, blood stasis, and blocked meridians, but these medications are limited in their effectiveness, have significant side effects, and are ineffective compared to some Western medications. Summary of the Invention

[0003] In view of the problems existing in the prior art, the present invention discloses a blood-activating and collateral-unblocking granule. The main ingredients and proportions by weight are: 190-200 parts of astragalus, 170-180 parts of kudzu root, 115-120 parts of hawthorn, 115-120 parts of ginkgo leaf, 75-80 parts of salvia miltiorrhiza, 55-65 parts of leek, 75-80 parts of rhodiola, 55-65 parts of wolfberry, 75-80 parts of stir-fried jujube seeds, 75-80 parts of acanthopanax senticosus, 65-70 parts of schisandra, and 65-70 parts of ophiopogon.

[0004] A method for preparing Huoxuetongluo granules comprises the following steps: Step 1: Ginkgo biloba leaves and stir-fried jujube seeds are selected in proportion, crushed, passed through a 100-mesh sieve, and mixed evenly to obtain a mixed fine powder for later use; Step 2: Select astragalus, kudzu root, hawthorn, salvia miltiorrhiza, schisandra, rhodiola, wolfberry, acanthopanax, schisandra chinensis, and ophiopogon japonicus in proportion, add 8 times the amount of water, soak for 1 hour, and then decoct. After 1.5 hours of decoction, take the decoction, add 7 times the amount of water, and decoct for 1 hour, take the decoction, combine the decoctions, let it stand, and take the supernatant; Step 3: Filter the supernatant with a 100-mesh filter and concentrate it to a relative density of 1.20-1.30 at 70°C. After the extract is passed through a 100-mesh sieve, add the mixed fine powder obtained in step 1 to make granules, dry them at 60°C, and obtain Huoxuetongluo granules.

[0005] As a preferred embodiment of the present invention, appropriate amounts of dextrin and maltitol can be added together with the mixed fine powder in step 3 as needed to prepare sugar-containing Huoxue Tongluo granules; or only appropriate amounts of dextrin can be added as needed to prepare sugar-free Huoxue Tongluo granules.

[0006] Lycium barbarum, also known as wolfberry, beet seed, red earring, and ground bone bark, has the benefits of improving eyesight and nourishing the liver and kidneys. It is mainly used to treat consumptive disease, spermatorrhea, lower back and knee pain, decreased vision, and vertigo and tinnitus. It has a sweet taste and a neutral nature. It enters the liver and kidney meridians.

[0007] Danshen (Danshen), also known as red root, dahongpao, and blood ginseng root, has the effects of promoting blood circulation, removing blood stasis, relieving pain during menstruation, clearing the heart and relieving restlessness, cooling blood, and eliminating carbuncles. It is used to treat chest pain, heartache, abdominal pain, and flank pain, accumulation of masses, pain caused by heat, restlessness, insomnia, irregular menstruation, dysmenorrhea, amenorrhea, and painful sores and swelling. It has a bitter taste and a slightly cold nature. It enters the heart and liver meridians.

[0008] Crataegus pinnatifida, also known as hawthorn, liangmei, hawthorn fruit, rat check, sheep twig, red claw fruit, tangtwig fruit, red date fruit, mountain red fruit, sour jujube, snot ball, persimmon hawthorn fruit, mountain fruit, and mao zha, has the effects of dissipating food stagnation and removing blood stasis. It is mainly used to treat food stagnation, abdominal distension and pain, diarrhea, dysmenorrhea due to blood stasis, amenorrhea, postpartum abdominal pain, and lochia retention. It tastes sour and sweet and is slightly warm in nature. It enters the spleen, stomach, and liver meridians.

[0009] Ziziphus jujuba seeds, also known as sour jujube kernels and jujube seeds, have the properties of calming the mind, nourishing the liver, astringing sweat, and strengthening the bones and muscles. They are used to treat wind in the bones and muscles, insomnia due to deficiency, palpitations, spontaneous sweating due to physical weakness, and night sweats. They are sweet and neutral in nature. They enter the heart, spleen, liver, and gallbladder meridians.

[0010] Ophiopogon japonicus, also known as Ophiopogon japonicus, Ophiopogon japonicus, and Ophiopogon japonicus, nourishes yin and promotes fluid production, moistening the lungs and clearing the heart. It is primarily used to treat dry coughs caused by lung dryness, consumptive coughs, thirst due to loss of fluid, restlessness and insomnia, internal heat and thirst, and constipation due to intestinal dryness. It has a sweet and slightly bitter flavor and a slightly cold nature. It enters the Heart, Lung, and Stomach meridians.

[0011] Schisandra chinensis, also known as Xuanji, Huiji, Wumeizi, and Shanhuajiao, has astringent properties, invigorates Qi and promotes fluid production, and calms the mind. It is primarily used to treat cough, asthma, nocturnal emission, spermatorrhea, excessive urination, chronic diarrhea, spontaneous sweating, night sweats, thirst due to fluid loss, palpitations, and insomnia. It has a sour flavor and warm properties. It enters the Lung and Kidney meridians.

[0012] Astragalus, also known as Jianqi, Baiben, Wangsun, Jinqi, Mianhuangqi, and Beiqi, has the effects of tonifying Qi and strengthening the exterior, expelling toxins and pus, promoting urination, and promoting tissue regeneration. It is primarily used to treat Qi deficiency and fatigue, chronic diarrhea and prolapse of the anus, spontaneous sweating, edema, uterine prolapse, proteinuria in chronic nephritis, diabetes, and persistent wounds. It has a sweet flavor and warm nature. It enters the Lung and Spleen meridians.

[0013] Pueraria root, also known as dried kudzu root, sweet kudzu root, powdered kudzu root, kudzu root, kudzu root, kudzu root, kudzu root, kudzu root, and kudzu root, has the effects of relieving muscles and reducing fever, promoting bowel movements, promoting fluid production and quenching thirst, and promoting yang and stopping diarrhea. It is primarily used to treat exogenous fever, stiff neck and headache, the initial onset of measles, delayed rash, thirst caused by febrile diseases, diabetes, diarrhea, dysentery, hypertension, and coronary heart disease. It has a sweet and pungent flavor and is neutral in nature. It enters the spleen and stomach meridians.

[0014] The beneficial effects of the present invention are as follows: the present invention selects ginkgo leaves, stir-fried spinach seeds, astragalus, kudzu root, hawthorn, salvia miltiorrhiza, allium macrostemon, rhodiola rosea, wolfberry fruit, acanthopanax senticosus, schisandra chinensis, and ophiopogon as raw materials, and after boiling, filtering, and concentrating, the raw materials are granulated. The materials are all natural Chinese medicinal ingredients, and the raw materials have the effects of promoting blood circulation, removing blood stasis, unblocking meridians, and relieving pain. The raw materials have obvious therapeutic effects on symptoms such as chest pain, heartache, dizziness, angina pectoris of coronary heart disease, hypertension, hyperlipidemia, cerebral arteriosclerosis, etc. caused by blood stasis and meridian obstruction, have no side effects on the body, are simple in preparation method, low in production cost, and have application and promotion prospects. DETAILED DESCRIPTION

[0015] Example 1

[0016] The Huoxuetongluo granules of the present invention mainly include ginkgo leaves, stir-fried jujube seeds, astragalus, kudzu root, hawthorn, salvia miltiorrhiza, leek, rhodiola rosea, wolfberry, acanthopanax senticosus, schisandra chinensis, and ophiopogon japonicus. The preparation method thereof comprises the following steps: Step 1: Select 115 parts of ginkgo leaves and 75 parts of stir-fried spinach seeds according to the proportion, grind them, pass them through a 100-mesh sieve, and mix them evenly to obtain a mixed fine powder for later use; Step 2, according to the proportion, select 190 parts of Astragalus, 170 parts of Pueraria, 115 parts of Crataegus, 75 parts of Salvia miltiorrhiza, 55 parts of Xiebai, 75 parts of Rhodiola, 55 parts of Lycium barbarum, 75 parts of Acanthopanax, 65 parts of Schisandra, and 65 parts of Ophiopogon japonicus, add 8 times the amount of water, soak for 1 hour, decoct after 1.5 hours, take the decoction, add 7 times the amount of water, decoct for 1 hour, take the decoction, combine the decoctions, let stand and take the supernatant; Step 3: Filter the supernatant with a 100-mesh filter and concentrate it to a relative density of 1.20 at 70°C. After the extract is passed through a 100-mesh sieve, add the mixed fine powder obtained in step 1, and add an appropriate amount of dextrin and an appropriate amount of maltitol to make granules, and dry them at 60°C to obtain sugar-containing Huoxue Tongluo granules; sugar-free Huoxue Tongluo granules can also be obtained without adding maltitol.

[0017] Example 2

[0018] The Huoxuetongluo granules of the present invention mainly include ginkgo leaves, stir-fried jujube seeds, astragalus, kudzu root, hawthorn, salvia miltiorrhiza, leek, rhodiola rosea, wolfberry, acanthopanax senticosus, schisandra chinensis, and ophiopogon japonicus. The preparation method thereof comprises the following steps: Step 1: Select 120 parts of ginkgo leaves and 80 parts of stir-fried spinach seeds according to the proportion, grind them, pass through a 100-mesh sieve, and mix them evenly to obtain a mixed fine powder for later use; Step 2, according to the proportion, select 200 parts of Astragalus, 180 parts of Pueraria, 120 parts of Crataegus, 80 parts of Salvia miltiorrhiza, 65 parts of Xiebai, 80 parts of Rhodiola, 65 parts of Lycium barbarum, 80 parts of Acanthopanax, 70 parts of Schisandra, and 70 parts of Ophiopogon japonicus, add 8 times the amount of water, soak for 1 hour, decoct after 1.5 hours, take the decoction, add 7 times the amount of water, decoct for 1 hour, take the decoction, combine the decoctions, let stand and take the supernatant; Step 3: Filter the supernatant with a 100-mesh filter and concentrate it to a relative density of 1.30 at 70°C. After the extract is passed through a 100-mesh sieve, add the mixed fine powder obtained in step 1, and add an appropriate amount of dextrin and an appropriate amount of maltitol to make granules, and dry them at 60°C to obtain sugar-containing Huoxue Tongluo granules; sugar-free Huoxue Tongluo granules can also be obtained without adding maltitol.

[0019] Example 3

[0020] The Huoxuetongluo granules of the present invention mainly include ginkgo leaves, stir-fried jujube seeds, astragalus, kudzu root, hawthorn, salvia miltiorrhiza, leek, rhodiola rosea, wolfberry, acanthopanax senticosus, schisandra chinensis, and ophiopogon japonicus. The preparation method thereof comprises the following steps: Step 1: Select 117 parts of ginkgo leaves and 78 parts of stir-fried spinach seeds according to the proportion, grind them, pass them through a 100-mesh sieve, and mix them evenly to obtain a mixed fine powder for later use; Step 2, according to the proportion of 196 parts of Astragalus, 176 parts of Pueraria, 117 parts of Crataegus, 78 parts of Salvia miltiorrhiza, 59 parts of Xiebai, 78 parts of Rhodiola, 59 parts of Lycium barbarum, 78 parts of Acanthopanax, 68 parts of Schisandra, and 68 parts of Radix Ophiopogonis, and soak them in 8 times the amount of water for 1 hour and then decoct them. After 1.5 hours of decoction, take the decoction, add 7 times the amount of water and decoct them for 1 hour, take the decoction, combine the decoctions, let it stand and take the supernatant; Step 3: Filter the supernatant with a 100-mesh filter and concentrate it to a relative density of 1.25 at 70°C. After the extract is passed through a 100-mesh sieve, add the mixed fine powder obtained in step 1, and add an appropriate amount of dextrin and an appropriate amount of maltitol to make granules, and dry them at 60°C to obtain sugar-containing Huoxue Tongluo granules; sugar-free Huoxue Tongluo granules can also be obtained without adding maltitol.

[0021] This granule product complies with the provisions of various granule items specified in General Chapter 0104 of Appendix IV of the 2020 edition of the Chinese Pharmacopoeia.

[0022] Components not described in detail herein are prior art.

[0023] Although the specific embodiments of the present invention have been described in detail above, the present invention is not limited to the above embodiments. Within the scope of knowledge possessed by ordinary technicians in this field, various changes can be made without departing from the purpose of the present invention. Modifications or deformations that do not involve creative work are still within the scope of protection of the present invention.

Claims

1. A granule for promoting blood circulation and unblocking meridians, characterized in that: The main ingredients and proportions by weight are: 190-200 parts of astragalus, 170-180 parts of kudzu root, 115-120 parts of hawthorn, 115-120 parts of ginkgo leaves, 75-80 parts of salvia miltiorrhiza, 55-65 parts of scutellaria baicalensis, 75-80 parts of rhodiola rosea, 55-65 parts of wolfberry, 75-80 parts of stir-fried jujube seeds, 75-80 parts of acanthopanax senticosus, 65-70 parts of schisandra chinensis, and 65-70 parts of ophiopogon.

2. The Huoxuetongluo granule according to claim 1, characterized in that: Including Astragalus 196 176 parts of kudzu root, 117 parts of hawthorn, 117 parts of ginkgo leaves, 78 parts of salvia miltiorrhiza, 59 parts of scutellaria baicalensis, 78 parts of rhodiola rosea, 59 parts of wolfberry fruits, 78 parts of stir-fried spinach seeds, 78 parts of acanthopanax senticosus, 68 parts of schisandra chinensis, and 68 parts of ophiopogon japonicus.

3. The method for preparing Huoxuetongluo granules according to claim 1, wherein: The steps are as follows: Step 1: Ginkgo biloba leaves and stir-fried jujube seeds are selected in proportion, crushed, passed through a 100-mesh sieve, and mixed evenly to obtain a mixed fine powder for later use; Step 2: Select astragalus, kudzu root, hawthorn, salvia miltiorrhiza, schisandra, rhodiola, wolfberry, acanthopanax, schisandra chinensis, and ophiopogon japonicus in proportion, add 8 times the amount of water, soak for 1 hour, and then decoct. After 1.5 hours of decoction, take the decoction, add 7 times the amount of water, and decoct for 1 hour, take the decoction, combine the decoctions, let it stand, and take the supernatant; Step 3: Filter the supernatant with a 100-mesh filter and concentrate it to a relative density of 1.20-1.30 at 70°C. After the extract is passed through a 100-mesh sieve, add the mixed fine powder obtained in step 1 to make granules, dry them at 60°C, and obtain Huoxuetongluo granules.