447 results about "Platycodon grandiflorus" patented technology

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating rhinitis. The traditional Chinese medicine composition comprises platycodon grandiflorum, semen armeniacae amarae, citrus chachiensis hortorum, fructus aurantii, aster, ephedra, radices trichosanthis, thunberg fritillary bulb, liquorice and loquat leaves. The traditional Chinese medicine composition can be used for remarkably relieving sneezing symptoms caused by allergic rhinitis, reducing histamine and specific IgE levels in serum and improving the pathological change degree of nasal mucosa tissues, and has a wide application prospect.

The invention discloses a medicinal and edible composition relaxing cream and a preparation method thereof. Comprising the following raw materials in parts by weight: 8-12 parts of kelp, 10-15 parts of oysters, 6-10 parts of fingered citron, 5-8 parts of dandelions, 5-8 parts of peach kernels, 10-15 parts of malt, 3-6 parts of brassica juncea, 10-15 parts of poria cocos, 5-8 parts of platycodon grandiflorum, 5-8 parts of fructus gardeniae, 8-12 parts of pericarpium citri reticulatae, 3-6 parts of rhizoma zingiberis, 10-15 parts of mulberries, 10-15 parts of rhizoma polygonati, 8-12 parts of codonopsis pilosula, 10-15 parts of hawthorn fruits, 3-6 parts of cinnamon, 5-8 parts of angelica sinensis and 3-6 parts of radix angelicae. The traditional Chinese medicine composition disclosed by the invention has the advantage of good use effect, and solves the problems that in the use process of the existing composition-relaxing cream, the multi-target synergistic effect is lacked, the curative effect is limited, heat-sensitive components are easy to degrade after long-time high-temperature boiling, and the drug effect exertion is influenced.

The invention provides a traditional Chinese medicine composition for treating early primary Parkinson's disease and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 2-5 parts of radix astragali, 2-5 parts of radix asparagi, 4-6 parts of radix polygonati officinalis, 1-3 parts of fructus gardeniae, 1-3 parts of fermented soybean, 2-5 parts of fructus trichosanthis, 1-3 parts of radix curcumae, 2-5 parts of radix angelicae sinensis, 1-3 parts of rhizoma chuanxiong, 5-7 parts of radix paeoniae alba, 2-5 parts of caulis spatholobi, 1-3 parts of semen persicae, 1-3 parts of semen armeniacae amarae, 2-5 parts of fructus cannabis, 3-5 parts of radix asteris and 1-3 parts of radix platycodonis. And 15-20 parts by weight of an auxiliary material. The invention also provides a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition provided by the invention can realize a treatment effect on the early primary Parkinson's disease.

The invention provides a traditional Chinese medicine monomer composition for preventing and / or treating pulmonary fibrosis as well as a preparation and application thereof, and belongs to the technical field of biological medicines. The traditional Chinese medicine monomer composition comprises the following components: schisandrin B and platycodin D. The traditional Chinese medicine monomer composition can obviously reduce fiber cell and collagen deposition, relieve inflammatory cell infiltration, obviously reduce the lung coefficient, alveolar inflammation score and pulmonary fibrosis score, and recover the normal physiological structure of rat lung tissue. The traditional Chinese medicine monomer composition provided by the invention can reduce the expression contents of KL-6, MMP-7, SP-A and SP-D and lung tissue HYP in serum, and has the effects of relieving collagen deposition and alveolar epithelium injury, maintaining alveolar homeostasis and improving pulmonary fibrosis. Therefore, the traditional Chinese medicine composition provided by the invention is definite and reliable in curative effect and can be used for preparing medicines for preventing and / or treating pulmonary fibrosis.

The invention belongs to the field of traditional Chinese medicines, and particularly relates to an inhalation type pharmaceutical composition for treating inflammatory respiratory diseases and a preparation method thereof. The inhalation type pharmaceutical composition comprises an active component and a nano-liposome, and mannose is modified on the surface of the nano-liposome; the active ingredients comprise bulbus fritillariae cirrhosae total alkaloids and platycodin D; the nano-liposome is prepared from the following raw materials: phospholipid, cholesterol and cholesterol-polyethylene glycol 1000-mannose ester. The liposome can be specifically recognized by a mannose receptor highly expressed on the surface of alveolar macrophage through a surface-modified mannose ligand, so that the receptor-mediated endocytosis is started, and the wrapped bulbus fritillariae cirrhosae total alkaloids and platycodin D are efficiently introduced into cells. The inhaled pharmaceutical composition of the present invention collectively pushes macrophages from a pro-inflammatory M1 phenotype to a repairable M2 phenotype. Therefore, the overall curative effect of the combination of the two components is far better than that of the independent use of any component.

The application provides a Chinese medicine compound preparation for preventing and treating respiratory tract infection of livestock and poultry, a preparation method and application, and relates to the technical field of animal medicine. The Chinese medicine compound preparation is composed of 10 Chinese medicines, i.e. honeysuckle, forsythia, inula flower, platycodon grandiflorum, euphorbia helioscopia, xiaochangqing, fresh eucalyptus globulus, fried stemona, cat's claw and augustifolia, follows the principle of Chinese medicine syndrome differentiation and treatment, is reasonably matched, and the medicines are coordinated with each other to increase the efficacy. The Chinese medicine compound preparation can significantly reduce the levels of TNF-alpha and IL-6 in serum, increase the level of IFN-gamma, obviously alleviate the clinical symptoms of livestock and poultry respiratory tract infection, reduce the mortality, has a good treatment effect on the related diseases of livestock and poultry respiratory tract infection, can improve the drug resistance of antibiotic drugs, reduce the drug residues of chemical agents in livestock and poultry, and guarantees the health of livestock and poultry and the safety of animal source food.

A traditional Chinese medicine composition for treating pulmonary nodules, wherein the composition is prepared from the following traditional Chinese medicines in parts by weight: a principle drug selected from one or more of 10-45 parts of raw Astragali radix, 10-25 parts of Sargassum, and 10-25 parts of Arisaematis rhizoma preparatum; a minister drug selected from one or more of 10-25 parts of Fritillariae thunbergii bulbus, 10-25 parts of Forsythiae fructus, 10-25 parts of stir-fried Atractylodis macrocephalae rhizoma, 1T0 part of Hirudo, 10-25 parts of Dioscoreae nipponicae rhizoma, 10-35 parts of Adenophorae radix, 10-35 parts of honey-processed Mori cortex, 10-25 parts of Perillae fructus, 10-25 parts of Peucedani radix, 10-35 parts of Phragmitis rhizome, 10-45 parts of raw Coicis semen, 5-25 parts of vinegar-processed Cyperi rhizoma, 10-25 parts of Aurantii fructus, 10-25 parts of Paeoniae radix alba, 10-35 parts of Scutellariae barbatae herba, 10-35 parts of Herba duchesneae indicae, 10-35 parts of Salviae chinensis herba, 5-20 parts of Menispermi rhizoma, 5-20 parts of Momordicae semen, 10-25 parts of Curcumae rhizoma, and 5-20 parts of Gleditsiae spina; an assistant drug selected from one or more of 5-25 parts of vinegar-processed Bupleuri radix, 5-25 parts of Citri reticulatae pericarpium, 10-25 parts of Perillae fructus, 2-12 parts of processed Ephedrae herba, 10-25 parts of Cynanchi stauntonii rhizoma et radix, 5-20 parts of Typhonii rhizoma, 2-12 parts of Zingiberis rhizoma, 10-35 parts of Morindae officinalis radix, 10-35 parts of Scutellariae barbatae herba, 10-45 parts of Radix aconiti lateralis praeparata nigra, and 10-25 parts of Typhonii rhizoma praeparata; and an envoy drug selected from one or more of 5-20 parts of Fagopyri dibotryis rhizoma, 10-25 parts of Platycodonis radix, 10-25 parts of Paeoniae radix alba, and 5-25 parts of Glycyrrhizae radix et rhizoma praeparata cum melle.

The invention discloses a traditional Chinese medicine composition for preventing and treating metabolism-related fatty liver diseases or metabolic syndromes. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 5-50 parts of sweet wormwood, 3-30 parts of scutellaria baicalensis, 5-50 parts of dandelion, 4-60 parts of platycodon grandiflorum, 5-50 parts of fructus aurantii, 3-80 parts of rhizoma pinelliae preparata, 3-70 parts of fructus amomi, 10-80 parts of stir-fried Chinese yam, 5-80 parts of poria cocos and 3-100 parts of raw coix seeds. The traditional Chinese medicine composition for preventing and treating the metabolism-related fatty liver diseases or the metabolic syndromes is simple in formula, proper in compatibility and mild in medicine property, is used for preventing and treating the metabolism-related fatty liver diseases or the metabolic syndromes, is used for improving liver fatty degeneration and inflammation, blood uric acid, blood fat, blood sugar and blood pressure, assisting weight loss and the like, and is safe to use and remarkable in curative effect.

The invention discloses a traditional Chinese medicine composition for treating hashimoto's thyroiditis and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from 12-25 parts of wine-processed rhizoma polygonati, 18-30 parts of Chinese yam, 6-15 parts of pericarpium citri reticulatae, 3-12 parts of fructus amomi, 25-40 parts of semen coicis fried with bran, 8-16 parts of fried fructus gardeniae, 8-16 parts of rhizoma phragmitis, 8-16 parts of chrysanthemum, 8-16 parts of folium mori, 8-16 parts of radix polygonati officinalis, 10-15 parts of lily, 8-16 parts of honeysuckle, 12-25 parts of herba portulacae and 8-16 parts of radix angelicae. , 3-12 parts of platycodon grandiflorum and 3-12 parts of mint. The traditional Chinese medicine composition adopts the theory of syndrome differentiation and treatment, and clinical experiment results and animal experiment results show that the traditional Chinese medicine composition can improve clinical symptoms of patients with hashimoto's thyroiditis, can be used for treating hashimoto's thyroiditis, and has the advantages of remarkable treatment effect, high safety, homology of medicine and food and no toxic or side effect.

The invention provides a traditional Chinese medicine composition for treating acute altitude sickness. The traditional Chinese medicine composition is prepared from ginseng, astragalus membranaceus, acanthopanax, rhodiola rosea, turnip, salvia miltiorrhiza, dogwood, poria cocos, rhizoma cimicifugae, radix bupleuri, platycodon grandiflorum, aster, elecampane, rhizoma anemarrhenae and liquorice. The traditional Chinese medicine composition disclosed by the invention can be used for treating the acute altitude sickness, remarkably prolonging the load-bearing swimming time of rats, remarkably increasing the arterial oxygen partial pressure and the arterial oxygen saturation of acute altitude sickness model rats and relieving physical fatigue, has obvious effects of resisting anoxia, improving acid-base balance and resisting inflammation, and has obvious curative effects on myocardial injury, liver injury, liver injury and the like. And the kidney injury can be protected.

The invention belongs to the technical field of plant fermented beverages, and particularly relates to a synergistically fermented composite plant beverage and a preparation method thereof. The preparation method comprises the following steps: sieving platycodon grandiflorum and liquorice, and then carrying out ultrasonic pretreatment and cold extraction to obtain a platycodon grandiflorum and liquorice cold extraction solution; adding pectinase and beta-glucosidase into the pear juice, and carrying out enzymolysis composite treatment, so as to obtain pear juice after enzymolysis; mixing the platycodon grandiflorum and liquorice cold extraction liquid and the pear juice subjected to enzymolysis to obtain a cold extraction mixed liquid, and then inoculating a combined strain for fermentation to obtain a fermented mixed liquid; and performing molecular distillation and concentration on the fermentation mixed solution, and then performing high-pressure carbon dioxide sterilization and photodynamic sterilization in sequence to obtain the product. According to the preparation method disclosed by the invention, the preparation time is effectively shortened, the energy consumption is reduced, the preparation efficiency is improved, and the prepared composite plant beverage is high in content of active ingredients and nutrient elements such as GABA, platycodin and the like, long in storage time and high in storage stability.

The invention discloses a blood fat reducing composition with homology of medicine and food and a preparation method thereof, and belongs to the technical field of homology of medicine and food. The medicinal and edible blood fat reducing composition comprises the following raw materials in parts by mass: 8-15 parts of peach kernels, 10-20 parts of sea-buckthorn, 6-12 parts of Chinese wolfberry fruits, 3-6 parts of platycodon roots, 4-8 parts of dried orange peel and 5-10 parts of microcapsules. The microcapsule consists of a core material and a wall material, wherein the core material comprises stigma croci, bamboo leaf flavone, earthworm protein peptide powder and natto; the wall material comprises gelatin, sodium carboxymethyl cellulose and Arabic gum-maltodextrin mixed powder. In addition, the invention also provides a preparation method of the blood fat reducing composition. The blood fat reducing composition provided by the invention realizes safe and efficient blood fat reduction.

The application relates to the technical field of cough-relieving medicines, and discloses a high-efficiency cough-relieving loquat particle composition which is composed of the following components in parts by weight: loquat leaf extract 30-40 parts; white front extract 10-15 parts; platycodon grandiflorum extract 6-10 parts; white mulberry bark extract 18-25 parts; stemona sessiliflora extract 7-10 parts; menthol 0.1-0.5 part; polyethylene glycol 2-5 parts; mannitol 8-12 parts; ethyl cellulose 3-6 parts; hydroxypropyl methyl cellulose 1-3 parts; phosphatidylcholine 1-3 parts; polysorbate 80 1-3 parts; cross-linked sodium carboxymethyl cellulose 4-6 parts; and sucrose 40-60 parts. The double dispersion system combining the immediate-release component and the sustained-release component is adopted, the solubility and the initial release speed of the traditional Chinese medicine extract are remarkably improved through the addition of polyethylene glycol and mannitol, and the technical effect that the drug effect appearing time is remarkably shortened is achieved. Compared with the technical scheme relying on only a single release mode in the prior art, the deficiency that the drug effect is slow and the symptoms of the patient cannot be timely relieved is solved.

The present invention discloses Jiangzhuo Quyu Granules for treating hyperlipidemia, which is a preparation made from raw medicinal materials in the following weight ratios: 20 - 30 parts of ginseng, 15 - 25 parts of atractylodes macrocephala, 20 - 30 parts of poria cocos, 18 - 22 parts of cuscuta chinensis, 12 - 18 parts of eucommia ulmoides, 10 - 20 parts of dipsacus asperoides, 20 - 30 parts of wolfberry fruit, 15 - 25 parts of safflower, 20 - 30 parts of motherwort, 10 - 20 parts of notoginseng, 10 - 20 parts of cistanche deserticola, 20 - 30 parts of cinnamon, 15 - 25 parts of epimedium, 12 - 18 parts of pinellia ternata, 20 - 30 parts of platycodon grandiflorum, 10 - 20 parts of fritillaria cirrhosa, 20 - 30 parts of sterculia lychnophora, 20 - 30 parts of peucedanum praeruptorum, 15 - 25 parts of mulberry bark, 20 - 30 parts of immature bitter orange, 15 - 25 parts of magnolia officinalis, and also discloses its preparation method and use in the preparation of drugs for treating hyperlipidemia, and the hyperlipidemia is of the phlegm-turbidity obstruction syndrome type.

The invention discloses a method for extracting and preparing an oligosaccharide extract from codonopsis pilosula and application of the oligosaccharide extract in prevention and treatment of neurodegenerative disease Alzheimer's disease, and belongs to the technical field of traditional Chinese medicine pharmacy. According to the present invention, the oligosaccharide extract is enriched and prepared from Codonopsis pilosala (Franch.) Nanf., wherein the Codonopsis pilosala (Franch.) Nanf. Is a plant of the family of Platycodon grandiflorum, and the activity test of the oligosaccharide extract on the improvement of cognitive dysfunction in the animal body is performed; results show that in a mouse cognitive function impairment model caused by sleep deprivation, the high-dose codonopsis pilosula oligosaccharide has a prominent effect on improving the learning and memory ability of a Morris water maze and a neuroprotective effect, the efficacy of the codonopsis pilosula oligosaccharide is equivalent to that of a positive control drug manntranet, and no obvious toxic or side effect is found. The codonopsis pilosula oligosaccharide is expected to be further developed into functional food, health care products and / or medicines with the effect of preventing and / or improving cognitive impairment.

This invention discloses a traditional Chinese medicine composition for improving fever in wind-heat common cold, belonging to the field of traditional Chinese medicine preparation technology. Addressing the shortcomings of existing Western medicines that suppress fever through central nervous system suppression, easily damaging organs and inhibiting microcirculation, and the limitations of traditional Chinese medicine preparations such as bitter and cold properties that astringe pathogens, causing low-grade fever rebound, damaging yin and spleen, and insufficient ability to resolve phlegm and strengthen the body, this invention innovatively combines the principles of monarch, minister, assistant, and guide herbs in a synergistic formulation based on the core microscopic pathogenesis of wind-heat common cold: "constriction of visceral microvessels, stagnation of heat pathogens, high fever depleting body fluids, fluid deficiency and blood stasis, and phlegm production due to stagnation." This invention is prepared using gardenia, platycodon, angelica, peppermint, ophiopogon, dandelion, lily, coix seed, and rehmannia as core raw materials. It utilizes pungent and dispersing herbs to open up the microcirculation of the body surface and lungs, dispersing stagnant heat and replacing the traditional bitter and cold heat-suppressing mechanism. Combined with heat-clearing and anti-inflammatory components, it targets and inhibits the release of inflammatory factors, resulting in stable fever reduction. Small doses of yin-nourishing herbs repair the damage to body fluids and blood caused by high fever, reversing the pathology of fluid deficiency and blood stasis. Spleen-strengthening and dampness-removing herbs harmonize the medicinal properties and strengthen the spleen. This invention achieves a balance of hot and cold properties, and addresses both tonification and purgation, providing a one-stop solution for complex symptoms such as fever, sore throat, nasal congestion, yellow phlegm, dry mouth, weakness, and fatigue caused by dampness in wind-heat colds. It provides stable fever reduction without rebound, and avoids the side effects of Western medicine and bitter and cold Chinese patent medicines. It addresses both the symptoms and the root cause, effectively avoiding post-cold sequelae and reducing the recurrence rate. Furthermore, the preparation process is simple, allowing for processing into various dosage forms, suitable for industrial mass production and widespread clinical application, possessing extremely high medical value and market potential.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for promoting blood circulation, excreting dampness and reducing blood pressure and a preparation method and application thereof. The active ingredient of the traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 3-10 parts of prepared radix aconiti lateralis preparata, 5-15 parts of rhizoma zingiberis, 5-15 parts of honey-fried licorice root, 5-15 parts of wine-processed radix cyathulae, 10-30 parts of radix salviae miltiorrhizae, 10-30 parts of radix paeoniae rubra, 10-30 parts of radix puerariae, 10-30 parts of rhizoma alismatis and 5-15 parts of radix platycodonis. The traditional Chinese medicine has the effects of tonifying deficiency, dispelling excess, promoting blood circulation, excreting dampness, reducing blood pressure and strengthening the body resistance, not only strengthens healthy qi to treat root causes, but also promotes blood circulation, excretes dampness to treat symptoms, and achieves the effect of treating both symptoms and root causes. Clinical research shows that the traditional Chinese medicine composition can promote blood circulation, excrete dampness and support healthy qi, so that the blood pressure level of a hypertensive patient is reduced, and the purpose of effectively treating hypertension is achieved.

The invention discloses a traditional Chinese medicine composition for treating cough. The invention belongs to the field of traditional Chinese medicine for treating cough. The traditional Chinese medicine composition is prepared from 17 traditional Chinese medicines including thunberg fritillary bulb, semen lepidii, platycodon grandiflorum, perilla leaf, almond, polygala tenuifolia, schisandra chinensis and the like. The cough is not injured by lung and cough, not injured by spleen and not coughed for a long time, and not injured by kidney and not cough and asthma, and the cough is not cured for a long time and is mostly caused by lung yin deficiency and kidney deficiency. Years of research finds that the fundamental cause of cough is lung qi upflow and phlegm obstructing lung regardless of external infection, internal injury and deficiency and excess symptoms, and the basic thought of treatment is to reduce phlegm and expel fluid retention; the lung qi is reduced; and tonifying spleen and kidney. According to the theory, the traditional Chinese medicines are screened according to the principle of syndrome differentiation and treatment of traditional Chinese medicine, and the prescription is an empirical prescription which is continuously explored and gradually formed in the practice process. The traditional Chinese medicine composition has a treatment effect on cough.

According to the traditional Chinese medicine prescription, radix scrophulariae, wild buckwheat rhizome, platycodon grandiflorum and radix angelicae have the effects of detoxifying and expelling pus and are used as monarch drugs, radix angelicae sinensis, radix paeoniae rubra, cowherb seed and beautiful sweetgum fruit have the effects of activating blood and dredging orifices as auxiliary drugs, radix astragali, radix saposhnikoviae, pericarpium citri reticulatae and honey-fried licorice root have the effects of tonifying qi and regulating the spleen and stomach as guide drugs, periostracum cicada and stiff silkworm have the effects of dredging collaterals as assistant drugs, and through clinical observation of thousands of cases, the traditional Chinese medicine prescription has the advantages of quick curative effect, no toxic or side effect and the like. The effective rate can reach 100%, and the clinical cure rate is 70% or above.

The invention discloses a highland barley wine composition with a liver protection effect as well as a preparation method and application of the highland barley wine composition, and relates to the technical field of traditional Chinese medicine compositions. The highland barley wine comprises the following raw materials in parts by weight: 30-600 parts of highland barley wine, 2-10 parts of dandelion, 3-10 parts of dried lalang grass rhizome, 2-15 parts of orange peel, 6-15 parts of cinnamon, 5-15 parts of poria cocos, 2-10 parts of platycodon grandiflorum, 3-10 parts of liquorice, 3-10 parts of kudzu vine root and 3-15 parts of hawthorn. According to the highland barley wine composition, the problem that heat-sensitive liver protection components are easy to degrade due to high temperature in a traditional process is solved through a stepped heating sterilization mode, high-activity components are reserved, and it is ensured that effective components play a synergistic effect in key links such as hepatic cell oxidative stress inhibition and detoxification enzyme activity adjustment; a plurality of traditional Chinese medicine raw material components and the highland barley wine form an anti-oxidation-anti-inflammatory-regeneration-promoting triple synergistic protection network, so that the liver protection function of the highland barley wine is enhanced.

The application belongs to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating abdominal distension and diarrhea of cold-heat complex type and a preparation method thereof. The technical scheme points of the traditional Chinese medicine composition are as follows: the traditional Chinese medicine composition is composed of the following raw medicinal materials in parts by weight: 3-6 parts of perilla, 3-10 parts of dried ginger, 3-12 parts of eucommia, 3-10 parts of scrophularia, 2-6 parts of coptis, 10-20 parts of fried coix seed, 6-10 parts of clear pinellia, 3-10 parts of dried tangerine or orange peel, 10-15 parts of poria, 6-10 parts of wheat-cooked atractylodes, 6-10 parts of vinegar-cured corydalis, 6-10 parts of vinegar-cured bupleurum, 6-10 parts of pericarpium zephyritae, 6-10 parts of chuanxiong, 6-10 parts of magnolia officinalis, 6-10 parts of fried hawthorn fruit, 3-6 parts of platycodon, and 3-10 parts of fried licorice. The traditional Chinese medicine composition and the traditional Chinese medicine water pill prepared from the traditional Chinese medicine composition have the effect of treating abdominal distension and diarrhea of cold-heat complex type.

The application belongs to the field of traditional Chinese medicines, and particularly relates to a more low-irritation analgesic ancient prescription microemulsion gel and application thereof in anti-arthritis drugs. The application finds that after water-soluble and fat-soluble components of black plaster prepared from raw frankincense, myrrh, eaglewood, dragon's blood, Strychnos nux-vomica, Panax notoginseng, Oldenlandia diffusa, Venenum Bufonis, bovine bezoar, Stachys jamaicensis, Platycodon grandiflorum, Hirudo nipponia, Tinea, Solenopsis geminata, Scorpio, scorpio, red lead and sesame oil are extracted, a more low-irritation analgesic ancient prescription microemulsion gel is prepared; compared with the black plaster itself, the analgesic effect of the microemulsion gel is significantly improved, and the microemulsion gel has good anti-inflammatory effect and can be used for preparing anti-arthritis drugs; and the microemulsion gel has reduced toxicity and is more convenient to use.

The invention relates to platycodon grandiflorum polysaccharide as well as a preparation method and application thereof. The structural formula of the platycodon grandiflorum polysaccharide is shown in the specification. The preparation method of the platycodon grandiflorum polysaccharide comprises the following steps: extracting platycodon grandiflorum crude polysaccharide from degreased platycodon grandiflorum by adopting a water extraction and alcohol precipitation method, and then decoloring, deproteinizing and purifying to obtain the platycodon grandiflorum polysaccharide PGP. And further preparing a platycodon grandiflorum polysaccharide calcium chelate and a platycodon grandiflorum polysaccharide zinc chelate by utilizing the platycodon grandiflorum polysaccharide PGP. Experiments prove that the prepared platycodon grandiflorum polysaccharide calcium chelate has an anti-osteoporosis effect, and the platycodon grandiflorum polysaccharide zinc chelate has immunoregulatory activity and a probiotic effect of synchronously regulating intestinal microecology. The platycodon grandiflorum polysaccharide calcium / zinc chelate provided by the invention is beneficial to development and application of novel calcium / zinc supplementation agents.

The utility model relates to the technical field of straw returning, and discloses a straw returning deep smashing device which comprises a bearing frame, a smashing cylinder is arranged outside the bearing frame, two first guide plates are fixedly installed in the smashing cylinder, a smashing mechanism is arranged in the smashing cylinder, a returning mechanism is arranged in the bearing frame, and a second guide plate is fixedly installed in the returning mechanism. Straw is smashed through the two smashing rollers, the cleaning brush cleans the rotating smashing rollers, the problem that straw is not smashed sufficiently due to the fact that the straw adheres to the outer portions of the smashing rollers and affects follow-up straw smashing is avoided, the outer portion of the smashing cylinder can be knocked in a reciprocating mode through the knocking column, smashed platycodon grandiflorum adhering to the inner wall of the smashing cylinder falls, and the smashing efficiency is improved. The interior of the smashing barrel is kept clean, the falling speed of smashed platycodon grandiflorum is higher, a discharging opening is prevented from being blocked, a second spring drives an inserting column to be inserted into an inserting hole, an adjusting plate is fixed after being adjusted, and the wheat straw throwing range can be adjusted conveniently.

The invention discloses a traditional Chinese medicine composition for clearing away heat and toxic materials and a preparation method thereof.The traditional Chinese medicine composition for clearing away heat and toxic materials takes houttuynia cordata as a main medicine and is composed of folium mori, chrysanthemum, selfheal, rhizoma phragmitis, platycodon grandiflorum, lophatherum gracile, mint, agastache rugosus, raw liquorice, hawthorn, poria cocos, houttuynia cordata, the root of kudzu vine, Chinese yam, Chinese dates, fructus amomi, citron, white hyacinth beans and perilla leaves. Houttuynia cordata is used as a main medicine, has a strong heat-clearing and detoxifying effect and is matched with reed rhizome, lophatherum gracile and the like, reed rhizome can clear heat, purge fire, promote salivation and quench thirst, lophatherum gracile can clear heat, relieve restlessness and induce diuresis, and the reed rhizome and the lophatherum gracile together enhance the heat-clearing capability of the whole composition, so that the heat-clearing and detoxifying effect is more comprehensive; folium mori can dispel wind and heat, clear away lung-heat and moisten dryness, chrysanthemum can clear liver, improve eyesight and clear away heat and toxic materials, and the folium mori, chrysanthemum and mint have good relieving effects on headache, fever, red eye swelling and pain and other symptoms caused by exogenous wind and heat together.

The invention discloses a traditional Chinese medicine composition and a traditional Chinese medicine decoction, and relates to the technical field of traditional Chinese medicine prescriptions. The traditional Chinese medicine composition is prepared from the following components in parts by weight, the traditional Chinese medicine composition is prepared from 5-15 parts of almonds, 5-15 parts of perilla leaves, 5-15 parts of schizonepeta, 5-15 parts of radix peucedani, 5-15 parts of snakegourd fruit shells, 5-15 parts of exocarpium citri grandis, 5-15 parts of roasted ephedra, 15-45 parts of gypsum, 5-15 parts of angelica sinensis, 5-15 parts of mangnolia officinalis, 3-10 parts of platycodon grandiflorum, 5-15 parts of stiff silkworms, 10-20 parts of radix asteris, 5-15 parts of radix stemonae, 5-15 parts of cynanchum glaucescens, 5-15 parts of roasted polygala tenuifolia, 15-45 parts of poria cocos, 5-15 parts of rhizoma pinellinae praeparata, 5-15 parts The traditional Chinese medicine decoction is prepared by decocting the traditional Chinese medicine composition with water. The traditional Chinese medicine decoction has the effects of dispelling wind and relieving exterior syndrome, ventilating lung and transforming fluid retention, and removing phlegm and relieving cough, is mainly used for treating cough caused by cold, 2019-nCoV virus infection and mycoplasma infection, and can eliminate respiratory tract inflammation.

The application belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition and a preparation method and application thereof, active ingredients of the traditional Chinese medicine composition including a fermentation product prepared by subjecting traditional Chinese medicine raw materials to anaerobic solid-state fermentation in combination with Lactobacillus helveticus and enzyme preparation; the traditional Chinese medicine raw materials include ginseng, poria cocos, Chinese yam, white lentil, lotus seed, yiyi seed, amomum villosum, platycodon grandiflorum, licorice and dried tangerine or orange peel; and the enzyme preparation includes cellulase and / or cellobiase. The application effectively promotes dissolution of effective ingredients of Shenlingbaizhu powder, significantly enriches antioxidant active ingredients in the fermentation product, relieves inhibition of oxidative stress on immune cells, and greatly improves survival rate and phagocytic efficacy of macrophages, so that the application shows a significant antibacterial pneumonia effect and has an excellent application prospect.

The invention discloses a medicinal and edible traditional Chinese medicine composition with the effects of regulating immunity, relieving fatigue and relieving sore throat and a preparation method of the medicinal and edible traditional Chinese medicine composition, and belongs to the technical field of medicinal and edible traditional Chinese medicine compositions.The medicinal and edible traditional Chinese medicine composition is prepared from 100 parts of phyllanthus emblica, 30-70 parts of astragalus membranaceus, 30-70 parts of fructus lycii, 1-20 parts of platycodon grandiflorum and 1-20 parts of mint. The preparation method comprises the following steps: crushing the phyllanthus emblica, the astragalus membranaceus, the platycodon grandiflorum and the mint into coarse powder, adding an ethanol aqueous solution with the concentration of 50wt% or above, carrying out ultrasonic treatment and heating treatment, and adding water into the fructus lycii for ultrasonic treatment. According to the traditional Chinese medicine composition, radix astragali, fructus lycii, radix platycodonis and herba menthae which can synergistically regulate immunity and relieve sore-throat and moisten throat are compounded, and through an optimized extraction process, the traditional Chinese medicine composition can have good sensory quality, regulate immunity, relieve fatigue and relieve sore-throat and moisten throat.

The invention provides a Chinese herbal medicine preparation for treating avian infectious bronchitis virus variant infection, and relates to the technical field of medicine preparation. The Chinese herbal medicine preparation for treating avian infectious bronchitis virus variant infection is prepared from the following components in parts by weight: 12-20 parts of gynostemma pentaphyllum, 8-12 parts of fructus forsythiae, 4-8 parts of folium isatidis, 4-8 parts of honeysuckle, 12-20 parts of platycodon grandiflorum, 8-12 parts of perillaseed, 4-8 parts of codonopsis pilosula, 4-8 parts of scutellaria baicalensis and 4-8 parts of radix sophorae flavescentis. The Chinese herbal medicines are decocted into liquid medicine to feed poultry, bronchitis and complications caused by virus variant infection can be effectively treated, the physique of the poultry is enhanced, the immunity of the poultry is improved, the death rate of the poultry is reduced, the Chinese herbal medicines are decocted into the liquid medicine, feeding is easy, cost is low, and the Chinese herbal medicines are suitable for large-scale popularization and application. Even if the composition is taken for a long time, drug resistance generated in poultry bodies is low, and drug property residual quantity is small.

The invention discloses a traditional Chinese medicine composition for treating acute pharyngitis as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The technical problems to be solved are that the traditional Chinese medicine composition for treating acute pharyngitis is not suitable for long-term administration, is not suitable for sensitive people and is easy to damage spleen and stomach. The invention provides a traditional Chinese medicine composition for treating acute pharyngitis. The traditional Chinese medicine composition is prepared from the following raw materials: honeysuckle flower, fructus forsythiae, radix isatidis, herba menthae, radix bupleuri, fructus arctii, schizonepeta spike, gypsum, radix scutellariae, fructus gardeniae, radix platycodonis, radix paeoniae rubra, rhizoma phragmitis, semen armeniacae amarae, herba lophatheri, fructus aurantii, radix saposhnikoviae, medicated leaven, stiff silkworm and liquorice root. The traditional Chinese medicine composition disclosed by the invention can inhibit inflammatory reaction by inhibiting phosphorylation levels of PI3K / AKT and RAS / MAPK signal pathways AKT and MAPK, so that acute pharyngitis is improved.