558 results about "Coptis chinensis" patented technology

The present invention relates to the technical field of new drug indications, and specifically discloses a non-filling breast augmentation external skin-rejuvenating oil preparation and its preparation method and application. The preparation method of the external skin-rejuvenating oil preparation is as follows: (1) preparing a skin-rejuvenating oil alcohol extract freeze-dried powder: taking astragalus, angelica, epimedium, ginkgo, green peel, frankincense, rhubarb, chicken gizzard, scutellaria, coptis, phellodendron and borneol in a certain weight ratio and adding them together into a container, and then adding an ethanol solution with a volume fraction of 40%-70% to the container, soaking, flash extraction, filtrate concentration, freeze drying to obtain; (2) preparing a skin-rejuvenating oil preparation: dissolving the skin-rejuvenating oil alcohol extract freeze-dried powder and egg yolk lecithin in edible vegetable oil to obtain an oil phase; then dripping the oil phase into the water phase obtained by dissolving Tween 60 and glycerol in ultrapure water, stirring and high-speed shearing, high-pressure homogenization, and obtaining. The external skin-rejuvenating oil preparation of the present invention has the effect of promoting breast fullness and uprightness in a short period of time.

The present application is applicable to the field of medical technology, and provides a pharmaceutical composition for preventing and treating diabetic vascular calcification and a preparation method thereof, wherein the pharmaceutical composition comprises the following raw materials by mass: 15-25 parts of salvia miltiorrhiza, 9-12 parts of coptis chinensis, 9-12 parts of knotweed, 9-15 parts of rhodiola rosea and 9-12 parts of ebony. The present application uses a pharmaceutical composition prepared by compounding salvia miltiorrhiza, coptis chinensis, knotweed, rhodiola rosea and ebony in proportion, which can prevent and treat diabetic vascular calcification; in addition, it can also effectively improve blood sugar metabolism, and has the function of reducing aortic calcium salt deposition and improving aortic pathological morphology.

The invention relates to the field of shampoo preparation, and particularly discloses a preparation method of anti-hair-loss, hair-growth and oil-control shampoo based on plant active ingredients, which comprises the following steps: step 1, soaking folium artemisiae argyi and pepper in warm water of 50-60 DEG C for 30 minutes, decocting for 30 minutes with medium fire, and filtering to obtain a first extracting solution; the preparation method comprises the following steps: soaking soapberry, cacumen biotae, duckweed, fructus cnidii, fructus kochiae, angelica sinensis, radix rehmanniae, radix paeoniae alba, rhizoma atractylodis macrocephalae, coptis chinensis, golden cypress, scutellaria baicalensis, radix sophorae flavescentis and ligusticum wallichii for 2 hours, and decocting at 95-100 DEG C for 4 hours; a functional closed loop of'oil control purification-hair follicle activation-inflammation blocking 'is formed through a three-element synergistic mechanism of sapindus, cacumen biotae and duckweed, sapindus saponin constructs microenvironment balance through targeted removal of hair follicle fat suppository, cacumen biotae flavone activates a hair papilla cell proliferation signal channel, duckweed polysaccharide forms an anti-inflammatory protection barrier, and the anti-inflammatory effect is achieved. The three components form a three-dimensional protective network on the molecular level, so that the pathological process of seborrheic alopecia is effectively blocked.

The invention relates to the field of insomnia treatment, in particular to a traditional Chinese medicine composition for treating insomnia caused by upper heat, lower cold and middle-jiao deficiency, which comprises the following Chinese herbal medicines: smoked plum, processed monkshood, cassia twig, ginseng, angelica sinensis, asarum, rhizoma zingiberis, pericarpium zanthoxyli, golden cypress, coptis chinensis, bitter wine, polished round-grained rice, honey, lily, tuber fleeceflower stem, hericium erinaceus, polygala tenuifolia and poria with hostwood. The pill is prepared from a traditional Chinese medicine composition of dark plum, processed monkshood, cassia twig, ginseng, angelica sinensis, asarum, rhizoma zingiberis, pericarpium zanthoxyli, golden cypress, coptis chinensis, bitter wine, polished round-grained rice, honey, lily, tuber fleeceflower stem, hericium erinaceus, polygala tenuifolia and poria with hostwood. The traditional Chinese medicine composition can comprehensively improve insomnia symptoms caused by upper heat, lower cold and middle-jiao deficiency, and is quick in effect taking, high in safety and small in side effect.

The present invention provides a Chinese medicine composition for preventing and treating "milk disease" of Chinese mitten crab, and a preparation method and application thereof, and the present invention belongs to the technical field of Chinese medicine for aquatic animals. The Chinese medicine composition provided by the present invention comprises the following raw materials in parts by weight: 1 to 10 parts of coptis root, 1 to 10 parts of sappan wood, 1 to 10 parts of pomegranate peel, 1 to 10 parts of cloves, 1 to 10 parts of scutellaria and 1 to 10 parts of schisandra chinensis. The Chinese medicine composition provided by the present invention is for the prevention and treatment of "milk disease" of Chinese mitten crab caused by Metschnikowia bicuspidatum, and provides an efficient, safe and practical method, with an inhibition rate of more than 99.67%, low cost, simple preparation process, high raw material utilization rate, easy industrialization, and good development value and market prospects.

The invention discloses an aloe extract-containing antibacterial, anti-inflammatory, anti-aging and moisturizing composition capable of promoting wound repair and application of the aloe extract-containing antibacterial, anti-inflammatory, anti-aging and moisturizing composition. The composition provided by the invention is obtained by compounding the active ingredients such as the aloe extract, the coptis chinensis extract, the centella asiatica extract, the honeysuckle flower extract and the carboxymethyl chitosan, all the ingredients synergistically play the roles of resisting bacteria, diminishing inflammation, resisting aging, promoting wound repair and moisturizing, and the composition has a remarkable effect. Wherein the aloe extract is prepared by adopting a specific deep eutectic solvent (DES), so that the content of anthraquinone compounds in the aloe extract can be increased, and the effects of bacteriostasis, sterilization, inflammation diminishing, detoxification, moisturizing and wound healing promotion of aloe can be better exerted. Specific extract components and the aloe extract are compounded, so that the effect of the aloe extract can be enhanced, the adopted components are natural, mild, safe and low in irritation, and a basis is provided for preparing more medicine products which are antibacterial, anti-inflammatory, anti-aging, moisturizing and capable of promoting wound repair.

The invention discloses a traditional Chinese medicine composition for treating diabetes and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine compositions. The invention solves the problem of limited curative effect in the existing diabetes treatment. The traditional Chinese medicine composition comprises the following components: 3-15 parts of ginseng; 10 to 30 parts of poria cocos; 5-30 parts of bighead atractylodes rhizome; 10 to 30 parts of radix achyranthis bidentatae; 10 to 30 parts of rhizoma alismatis; 10 to 30 parts of radix rehmanniae recen; 5-30 parts of coptis chinensis; 3 to 20 parts of cortex cinnamomi; 5-20 parts of dried ginger; 3 to 20 parts of fructus momordicae; 10 to 30 parts of corn stigma; 3-20 parts of lotus leaves; 10 to 30 parts of radix astragali seu hedysari; 10-20 parts of Chinese wolfberry fruits; 5 to 15 parts of radix scrophulariae; 5 to 15 parts of Chinese angelica; 5-10 parts of snow lotus herb; 5 to 10 parts of trogopterus dung; and 5-10 parts of pyrrosia lingua. The traditional Chinese medicine composition can be used for treating type 2 diabetes mellitus, has the functions of regulating blood sugar and enhancing body metabolism, and is remarkable in curative effect.

The invention discloses a ganoderma lucidum liver-protecting pill and a preparation method thereof, and the ganoderma lucidum liver-protecting pill comprises the following components: 8-20% of ganoderma lucidum polysaccharide extract, 5-15% of coptis chinensis extract, 4-10% of pulvis fellis saponin extract, 3-8% of oriental wormwood, 2-8% of taurine, 1-3% of vitamin E and 2-6% of scleroprotein (ganoderma lucidum sclerotium extract). The auxiliary materials comprise microcrystalline cellulose, corn starch, licorice extract, polyvinyl alcohol and the like, and the balance is 100%. Therefore, the problem of ingredient inactivation caused by traditional high-temperature / solvent extraction is solved through process innovation (such as supercritical CO2 pressure 300bar / enzymolysis pH 5.0 parameter optimization), the dissolution rate is increased to be more than or equal to 90% in 30 minutes (traditional pills need 45 minutes and only 75%), the limitation of single ingredient liver protection is broken through through the synergistic effect of the composite ingredients, and the liver protection effect is improved. Animal experiments prove that a liver injury marker ALT / AST can be reduced by more than 50%, the hepatic fibrosis area can be reduced by 40%, the degradation rate of the active ingredients within 6 months in a stability test is less than or equal to 5%, and the comprehensive bioavailability is improved by 30% compared with that of a traditional product.

The invention belongs to the technical field of external preparations, and provides compound itching-relieving cream as well as a preparation method and application thereof. The compound itching-relieving ointment is prepared from the following components in parts by weight: 3 to 6 parts of rhizoma coptidis, 9 to 15 parts of radix scutellariae, 9 to 15 parts of radix et rhizoma rhei, 3 to 6 parts of herba schizonepetae, 3 to 6 parts of herba menthae, 1 to 3 parts of cortex moutan, 1 to 3 parts of sandalwood and 0.5 to 1 part of borneol. The compound antipruritic ointment has the effects of cooling, relieving itching, detoxifying and diminishing swelling, and is used for treating itching and eczema dermatitis itching caused by biting of various small insects such as mosquitoes and the like. According to the compound antipruritic ointment disclosed by the invention, a plurality of components are in synergistic interaction, so that a multi-target and multi-layer treatment effect is realized. The traditional Chinese medicine composition can be used for cooling, relieving itching, detoxifying and diminishing swelling from the source while quickly relieving itching, and a comprehensive and effective solution is provided for itching.

The invention discloses a traditional Chinese medicine composition for treating type 2 diabetes and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from, by weight, 11-15 parts of radix acanthopanacis semticosi, 5-15 parts of male silkworm moth, 7-17 parts of white ginseng, 5-11 parts of rhizoma polygoni cuspidati, 15-25 parts of rhizoma coptidis, 1-5 parts of cortex cinnamomi, 11-15 parts of fructus ligustri lucidi, 11-15 parts of common fenugreek seed, 7-17 parts of lithocarpus litseifolius, 3-7 parts of raw radix astragali and 1-3 parts of wild lucid ganoderma. , 3-9 parts of tribulus terrestris and 11-17 parts of nigella nigra seeds. The traditional Chinese medicine composition has the effect of balancing and stabilizing blood sugar, is short in treatment course, quick in effect and free of toxic and side effects, and has an excellent curative effect on treating diabetic complications.

The present invention discloses a traditional Chinese medicine composition for treating diabetes and a preparation method thereof, belonging to the technical field of traditional Chinese medicine compositions. The present invention solves the problem of limited curative effect existing in the treatment of existing diabetes. The present invention is composed of the following components: ginseng: 3-15 parts; poria cocos: 10-30 parts; atractylodes macrocephala: 5-30 parts; achyranthes bidentata: 10-30 parts; alisma orientale: 10-30 parts; rehmannia glutinosa: 10-30 parts; coptis chinensis: 5-30 parts; cinnamon: 3-20 parts; dried ginger: 5-20 parts; momordica grosvenori: 3-20 parts; corn stigma: 10-30 parts; lotus leaf: 3-20 parts; astragalus membranaceus: 10-30 parts; wolfberry: 10-20 parts; scrophularia ningpoensis: 5-15 parts; angelica sinensis: 5-15 parts; snow lotus flower: 5-10 parts; trogopterus dung: 5-10 parts; pyrrosia lingua: 5-10 parts. The present invention can be used for treating type 2 diabetes, has the functions of regulating blood sugar and enhancing body metabolism, and has remarkable curative effect.

The invention discloses a traditional Chinese medicine compound for reducing urine protein, a traditional Chinese medicine preparation and a preparation method thereof, belongs to the technical field of traditional Chinese medicine compounds, and solves the problems that although the existing western medicine can reduce the urine protein level of a patient to a certain extent, the adverse reaction risk is high; the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10-30 parts of prepared rehmannia root, 10-30 parts of Chinese yam, 10-30 parts of dogwood, 10-20 parts of achyranthes root, 5-15 parts of schisandra chinensis, 5-15 parts of semen cuscutae, 10-30 parts of corn stigma, 10-30 parts of rhizoma alismatis, 10-30 parts of astragalus membranaceus, 10-30 parts of fried fructus rosae laevigatae, 10-30 parts of gordon euryale seed, 5-15 parts of flatstem milkvetch seed, 5-30 parts of salvia miltiorrhiza, 3-10 parts of wine-treated rhubarb and 3-5 parts of wine-treated coptis chinensis. According to the traditional Chinese medicine composition, all the medicines are compatible, all the components complement each other, the effects of reducing urinary albumin and protecting the kidney are increased, all the components are reasonably compatible, and the effect of coordinating and synergism is achieved.

The invention relates to the technical field of antibacterial agents, in particular to a compound antibacterial agent of a plant polyphenol complex and a preparation method of the compound antibacterial agent. The compound antibacterial agent is prepared from the following raw materials in parts by weight: 20-30 parts of moutan bark extract, 20-30 parts of folium mori, 20-30 parts of a carrier, 10-20 parts of jerusalem artichoke extract, 10-20 parts of coptis chinensis extract, 2-4 parts of a tackifier and 1-3 parts of a microbial agent. According to the invention, paeonol in moutan bark, chlorogenic acid in mulberry leaves, berberine in coptis chinensis and inulin polyphenol in jerusalem artichoke can be combined with lipid of bacterial cell membranes, so that membrane permeability is increased, microbial metabolic enzymes are interfered, energy metabolism and biosynthesis are blocked, free radicals are removed, and antibacterial effects of other components are enhanced; folium mori is hydrolyzed through beta-glucosidase to release free polyphenol, gluconolactone adjusts the acid environment to promote polyphenol dissolution, and the antibacterial effect of the composite antibacterial agent is effectively improved.

The invention discloses a traditional Chinese medicine composition for treating gastroesophageal reflux and chronic gastritis, relates to the technical field of traditional Chinese medicines, and particularly aims to solve the problem of relatively narrow application prospects of treatment means applied to GERD at present in the background technology. Comprising rhizoma bletillae, calcined concha arcae, rhizoma pinelliae preparata, caulis bambusae in taeniam, fructus aurantii immaturus, pericarpium citri reticulatae, liquorice, poria cocos, coptis chinensis, fructus evodiae, platycodon grandiflorum and radix curcumae, and the traditional Chinese medicine composition is superior to western medicines, effective in treatment of the gastroesophageal reflux disease, small in side effect and economical and practical.

The invention discloses a phlebitis treatment gel containing a coptis chinensis-wine-treated rhubarb compound component and a preparation method of the phlebitis treatment gel. The active ingredients of the gel are coptis chinensis, rheum officinale and wine-treated rheum officinale in a mass ratio of (1.5-2.5): (1.5-2.5): 1, preferably 2: 2: 1. Lavender essential oil, tea tree essential oil, folium eucalypti essential oil and vinegar frankincense, radix trichosanthis and other traditional Chinese medicine auxiliary materials are used as auxiliary materials. The preparation method comprises the following steps: extracting twice with ethanol, mixing extracting solutions, adding borneol, menthol and essential oil, and finally gelling with carbomer. The phlebitis gel can be independently used or combined with indometacin to form dual-channel anti-inflammation, and the defects of skin atrophy, toxicity accumulation and the like of traditional phlebitis gel are overcome. The traditional Chinese medicine composition is clinically expanded and applied to first-stage pressure sores (without skin damage), acnes and mosquito bites, red and swollen of the first-stage pressure sores fade away within 3-5 days, red and swollen of the acnes are relieved by more than or equal to 60% when the traditional Chinese medicine composition is combined with oral medicine for 48 hours, the itching relieving effect on the mosquito bites is less than or equal to 30 minutes, and the curative effect on phlebitis is remarkably superior to that of 50% magnesium sulfate (Plt;

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating glycolipid metabolic diseases and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 15-19 parts of coptis chinensis, 10-15 parts of rhodiola rosea, 10-20 parts of gynostemma pentaphylla, 9-12 parts of kapok, 10-15 parts of soapberry, 9-15 parts of salvia miltiorrhiza, 10-15 parts of rhizoma alismatis, 9-12 parts of oriental wormwood, 9-12 parts of radix bupleuri, 5-10 parts of semen cassiae, 10-15 parts of rhizoma anemarrhenae, 10-15 parts of hawthorn, 6-9 parts of polygonum cuspidatum and 5-10 parts of fructus aurantii. The traditional Chinese medicine composition disclosed by the invention has the effects of inhibiting hyperlipidemia, hyperglycemia and hepatic lipid accumulation and relieving insulin resistance, and has a remarkable curative effect on relieving and treating glycolipid metabolic diseases.

The invention belongs to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating ulcerative colitis, which is characterized in that the traditional Chinese medicine composition is prepared by extracting the following raw medicinal materials in parts by weight: 5-15 parts of ginseng, 8-25 parts of cassia twig, 5-15 parts of nutmeg, 8-25 parts of poria cocos, 8-25 parts of roasted rhizoma atractylodis macrocephalae, 5-15 parts of rhizoma zingiberis, 10-30 parts of roasted semen coicis, 1-5 parts of indigo naturalis and 2-6 parts of coptis chinensis. According to the traditional Chinese medicine composition, ginseng, rhizoma atractylodis macrocephalae and poria cocos are used as monarch drugs together, and rhizoma atractylodis macrocephalae and poria cocos have the effects of replenishing qi to invigorate the spleen and eliminating dampness and excreting dampness together; semen coicis and rhizoma zingiberis are used as ministerial drugs and co-help the monarch drugs to resolve dampness and stop diarrhea; the traditional Chinese medicine composition has the functions of invigorating the spleen, replenishing qi, warming the kidney, stopping diarrhea, excreting dampness and removing toxicity, is mainly used for treating ulcerative colitis and irritable bowel syndrome (diarrhea type) clinically, can also be used for diagnosing'diarrhea 'and'stomachache' in traditional Chinese medicine, and can be used for treating clinical symptoms such as stomachache, diarrhea, mucus stool, even mucus purulent bloody stool, incomplete defecation, urgent defecation and abdominal distension.

The invention belongs to the technical field of traditional Chinese medicine extraction, and particularly relates to a coptis chinensis extraction process which comprises the following specific steps: coptis chinensis pretreatment: selecting dried coptis chinensis rhizomes, removing impurities and mildewed parts, washing the treated coptis chinensis twice with deionized water, removing surface dust, drying in a drying oven at 50-60 DEG C until the water content is less than 5%, and taking out the coptis chinensis; the dried coptis chinensis is smashed through a smashing device, the smashed coptis chinensis is sieved through a 80-100-mesh sieve, and uniform fine powder is obtained.In the coptis chinensis extraction technology, interference of fat-soluble impurities is reduced through degreasing pretreatment, the subsequent resin adsorption efficiency is improved, pigment and polar impurities can be selectively adsorbed through decoloration of resin, effective ingredients such as alkaloid can be reserved, and the extraction efficiency of coptis chinensis is improved; small molecular impurities can be accurately removed through a membrane separation technology, traditional activated carbon adsorption is replaced, loss of effective components is reduced, finally, efficient separation and purification are conducted through an acid-base precipitation method, and water-soluble impurities are synchronously removed.

The invention discloses a traditional Chinese medicine composition for treating severe acne as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine monomers in parts by weight: 10-20 parts of folium eriobotryae, 8-15 parts of honeysuckle, 6-12 parts of radix sophorae flavescentis, 5-15 parts of chrysanthemum, 8-15 parts of fructus arctii, 6-12 parts of cortex phellodendri, 10-20 parts of cortex mori radicis, 15-30 parts of oldenlandia diffusa, 15-30 parts of dandelion, 10-20 parts of lalang grass rhizome, 15-30 parts of calcined oyster shell, 6-12 parts of radix angelicae, 8-15 parts of oriental wormwood, 10-20 parts of radix paeoniae rubra, 3-9 parts of coptis chinensis and 10-20 parts of fructus forsythiae. , 10-20 parts of red sage root, 15-30 parts of Chinese violet, 6-12 parts of thunberg fritillary bulb, and 10-20 parts of prunella vulgaris. According to the traditional Chinese medicine formula, the effects of multiple traditional Chinese medicines are integrated, the effects of clearing away heat and drying dampness, cooling blood and detoxifying, and removing stasis and diminishing swelling are synergistically achieved, effective adjustment can be conducted on the constitution of acne patients with damp-heat in the lung and the stomach and heat toxin stasis, and the pathogenesis of acne is fundamentally improved.

The invention provides a traditional Chinese medicine gel emplastrum for treating gouty arthritis and a preparation method thereof, the traditional Chinese medicine gel emplastrum for treating gouty arthritis at least comprises a gel layer loaded with a traditional Chinese medicine extract, the traditional Chinese medicine extract comprises the following raw materials: semen coicis, cortex phellodendri, radix clematidis, kadsura coccinea, rhizoma atractylodis, rhizoma dioscoreae hypoglaucae, red psychotria leaf, alangium platanifolium, kadsura pepper stem, radix aconiti, radix aconiti agrestis, semen strychni, frankincense, myrrh, angelica sinensis, safflower carthamus, radix cyathulae, radix paeoniae rubra, rhizoma smilacis glabrae, lycopodium clavatum, radices hemerocallis, weeping willow twig, evodia lepta, swamp mahogany, radix sophorae flavescentis, herba andrographitis, Chinese lobelia, coptis chinensis, edible tulip, cassia twig, pepper and borneol; a matrix of the gel layer is prepared from the following raw materials in parts by weight: silk fibroin, polyvinyl pyrrolidone, azide-polyethylene glycol-carboxylic acid, 1-ethynyl cyclopropyl carboxylic acid, 2, 5-dicarboxylic acid-3, 4-ethylenedioxythiophene and glycerol. The traditional Chinese medicine gel emplastrum disclosed by the invention can achieve a good treatment effect through percutaneous absorption.

The invention discloses a traditional Chinese medicine composition for improving cerebral ischemia and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine preparation. The preparation method comprises the following steps: mixing, stirring and dispersing a polyurethane pressure-sensitive adhesive, a copper sulfide-polyacrylate glue solution, mixed traditional Chinese medicine powder, ethyl acetate and a penetration enhancer, and standing to obtain a drug-loaded composite pressure-sensitive adhesive; and coating a polyethylene backing layer with the drug-loaded composite pressure-sensitive adhesive, and then drying, evaporating and curing to obtain the traditional Chinese medicine composition. Ginseng is used as a monarch drug, astragalus membranaceus is used as a ministerial drug, fructus aurantii, caulis spatholobi, poria cocos, gastrodia elata and coptis chinensis are used as adjuvant drugs, and liquorice is used as a conductant drug, so that the whole traditional Chinese medicine composition can enhance qi and blood, improve microcirculation, protect neurons and reduce ischemia consequences, and can regulate the drug properties of all the drugs to play a synergistic effect. And then preparing the traditional Chinese medicine composition patch with photo-thermal penetration promotion to realize the treatment of cerebral ischemia.

The invention discloses a water quality conditioning agent based on plant extracts and a preparation method of the water quality conditioning agent, and belongs to the technical field of aquaculture. The water quality conditioning agent is prepared from the following raw materials in parts by weight: 14 to 18 parts of fructus schisandrae chinensis extract, 4 to 5 parts of fructus mume extract, 10 to 13 parts of rhizoma coptidis extract, 8 to 10 parts of glucosamine, 5 to 8 parts of chitosan, 3 to 6 parts of nitrifying bacteria, 2 to 4 parts of thiobacillus thiooxidans and 3 to 6 parts of zeolite powder. Through a four-dimensional synergistic mechanism of'plant active ingredient-chitosan slow release-microbial immobilization-zeolite adsorption ', the pH value, ammonia nitrogen, nitrite, hydrogen sulfide and bottom mud COD in tail water can be reduced and the dissolved oxygen amount can be increased under the condition of one-time addition, which indicates that the water quality regulator has a good effect of improving water quality.

The invention provides application of a traditional Chinese medicine composition in preparation of a medicine for preventing and / or treating ovarian dysfunction, and belongs to the technical field of biological medicine. The traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials in parts by weight: 8-10 parts of American ginseng, 2-4 parts of pseudo-ginseng, 55-65 parts of kudzuvine root, 42-48 parts of coptis chinensis, 42-48 parts of scutellaria baicalensis, 14-16 parts of stiff silkworm, 14-16 parts of rhizoma zingiberis, 42-48 parts of bitter gourd and 55-65 parts of rhizoma anemarrhenae. The traditional Chinese medicine composition has the effects of increasing the number of follicles and corpus luteum, restoring the duration of an estrus cycle and restoring the levels of serum hormones and sex hormone receptors. The traditional Chinese medicine composition provided by the invention provides a new means for preventing and treating ovarian dysfunction.

The invention discloses a traditional Chinese medicine compound preparation for treating insomnia and a preparation method thereof, the traditional Chinese medicine compound preparation is prepared from the following raw materials or alcohol and water of the following raw materials or water extract or honey-processed paste: 15-30g of lily, 15-30g of lucid ganoderma, 15-90g of vine of multiflower knotweed, 30-60g of cortex albiziae, 30-60g of nacre mother of pearl, 6-15g of coptis chinensis, 15-30g of spina date seed, 30-60g of poria with hostwood, 6-15g of polygala tenuifolia and 30-60g of magnetite. The preparation method comprises the following steps: uniformly mixing 30-60 g of lapis chloriti, 30-60 g of ligusticum wallichii, 10-15 g of schisandra chinensis, 3-10 g of cinnamon, 15-30 g of salvia miltiorrhiza, 30-60 g of oyster, 15-30 g of platycladi seed, 15-30 g of corydalis tuber and 15-30 g of rhizoma anemarrhenae with alcohol or water or refining honey to prepare paste, and preparing the paste into a required dosage form. The traditional Chinese medicine composition has the beneficial effects that after scientific and reasonable compatibility and preparation, the medicine effect has a synergistic effect, and the traditional Chinese medicine composition has the effects of nourishing yin, clearing heat, calming the heart and soothing the nerves and is used for treating insomnia caused by fire excess from yin deficiency and liver depression.

The application relates to a kind of acne-removing compositions and its preparation method, application, cosmetics.The acne-removing composition comprises: coptis chinensis, magnolia officinalis extract and costus root extract, the coptis chinensis and magnolia officinalis extract are extracted from the mixture of coptis chinensis and magnolia officinalis as extraction raw material, and the costus root extract is extracted from costus root as extraction raw material.The acne-removing composition provided in the application can inhibit sebaceous gland excessive secretion of oil and inhibit the growth of propionibacterium acnes, thereby can reduce skin inflammation and infection, and play the effect of preventing and treating acne.

The application provides a traditional Chinese medicine compound medicine composed of Coptis chinensis, Astragalus membranaceus, Panax notoginseng and Rehmannia glutinosa and application thereof in preventing and treating diabetes and diabetes complications, and experimental results show that the compound medicine has good prevention and treatment effects on diabetes and various diabetes complications such as diabetic heart disease, diabetic kidney disease and diabetic retinopathy.

The invention provides a culture method and an acclimatization and transplantation method for coptis chinensis test-tube plantlets, and belongs to the technical field of plant tissue culture. The method comprises the following steps: (1) disinfecting a coptis chinensis explant, inoculating the disinfected coptis chinensis explant into an MS basal culture medium, and culturing to obtain a sterile seedling; (2) inoculating the aseptic seedlings into an adventitious bud culture medium for adventitious bud culture to obtain adventitious buds; (3) inoculating the adventitious buds into a proliferation culture medium for proliferation culture to obtain proliferation seedlings; and (4) inoculating the proliferation seedlings into a rooting culture medium for rooting culture to obtain the coptis chinensis test-tube plantlets. When the adventitious bud, proliferation and rooting culture medium is used for culturing the coptis chinensis test-tube plantlet, the proliferation coefficient of the test-tube plantlet reaches 3.0, the rooting rate reaches 96.3%, and the survival rate of acclimatization and transplantation reaches 91.5% through seedling acclimatization and transplantation. The culture method provided by the invention is used for preserving the germplasm resources of the coptis chinensis, and provides a basic guarantee for the germplasm improvement of the subsequent medicinal material coptis chinensis.

The invention discloses ointment for preventing infantile hand-foot-and-mouth disease and a preparation method thereof. The ointment is prepared from coptis chinensis, sweet wormwood, honeysuckle, radix sophorae flavescentis, lithospermum, sanguisorba officinalis, radix isatidis, menthol, clove oil, vitamin A oil, vitamin E oil, roxburgh rose seed oil, olive oil, chamomile extract, honey and microcrystalline wax. On the basis of combination of traditional Chinese medicines and western medicines, traditional Chinese medicine components such as coptis chinensis, artemisia apiacea and honeysuckle and western medicine components such as vitamin A and vitamin E are combined, and the ointment for preventing the infantile hand-foot-and-mouth disease is prepared. The components have the effects of clearing away heat and toxic materials, resisting viruses, bacteria and inflammation and the like, and are beneficial to enhancing the immunity of the organism, inhibiting virus diffusion and relieving disease symptoms, so that the occurrence of the infantile hand-foot-and-mouth disease is effectively prevented.

The invention discloses a multi-target intervention-based plant compound gynecological anti-HPV (human papillomavirus) gel preparation, which comprises two parts, namely a compound plant extracting solution and an aqueous gel carrier, the compound extracting solution is derived from rheum officinale, scutellaria baicalensis, coptis chinensis, golden cypress, radix sophorae flavescentis, fructus cnidii, alum, gallnut, common carpesium fruit, radix angelicae, cortex dictamni, fructus kochiae, frankincense and myrrh; the anti-HPV gel preparation is obtained by mixing and stirring according to the proportion. Aiming at an intervention window that a patient is continuously infected but does not deteriorate to an operation stage, intervention is carried out by adopting an action mechanism of local epithelial micro-ecological restoration and mucosal immunity, E6 / E7 oncogenic protein expression is inhibited, L1 capsid assembly is damaged, key nodes of a virus life cycle are covered, and escape risks are reduced by multi-target collaborative anti-HPV (Human Papilloma Virus); by inhibiting an NF-kB / EMT signal axis, the cervical lesion progress risk is reduced; the safety is high and the curative effect is obvious.

The invention discloses a content determination method of a traditional Chinese medicine Qianjin coptis chinensis pill, which comprises the following steps: a test solution and a reference solution of the Qianjin coptis chinensis pill are taken for detection under the chromatographic conditions that a chromatographic column with octadecylsilane chemically bonded silica as a filler is adopted, a mobile phase A is selected from acetonitrile, and a mobile phase B is a buffer saline solution; and obtaining content information of the Qianjin coptis pill according to a detection result. The reference substances are catalpol, berberine hydrochloride, palmatine hydrochloride, epiberberine, coptisine, caffeic acid, ferulic acid, magnoflorine, jateorhizine and columbamine. The chemical components of the Qianjin coptis pill are comprehensively and systematically analyzed, and a technical method is provided for perfecting and improving the medicine quality standard of the Qianjin coptis pill and better controlling the medicine quality.