259 results about "Coptis chinensis" patented technology

The invention discloses an aloe extract-containing antibacterial, anti-inflammatory, anti-aging and moisturizing composition capable of promoting wound repair and application of the aloe extract-containing antibacterial, anti-inflammatory, anti-aging and moisturizing composition. The composition provided by the invention is obtained by compounding the active ingredients such as the aloe extract, the coptis chinensis extract, the centella asiatica extract, the honeysuckle flower extract and the carboxymethyl chitosan, all the ingredients synergistically play the roles of resisting bacteria, diminishing inflammation, resisting aging, promoting wound repair and moisturizing, and the composition has a remarkable effect. Wherein the aloe extract is prepared by adopting a specific deep eutectic solvent (DES), so that the content of anthraquinone compounds in the aloe extract can be increased, and the effects of bacteriostasis, sterilization, inflammation diminishing, detoxification, moisturizing and wound healing promotion of aloe can be better exerted. Specific extract components and the aloe extract are compounded, so that the effect of the aloe extract can be enhanced, the adopted components are natural, mild, safe and low in irritation, and a basis is provided for preparing more medicine products which are antibacterial, anti-inflammatory, anti-aging, moisturizing and capable of promoting wound repair.

The invention belongs to the technical field of external preparations, and provides compound itching-relieving cream as well as a preparation method and application thereof. The compound itching-relieving ointment is prepared from the following components in parts by weight: 3 to 6 parts of rhizoma coptidis, 9 to 15 parts of radix scutellariae, 9 to 15 parts of radix et rhizoma rhei, 3 to 6 parts of herba schizonepetae, 3 to 6 parts of herba menthae, 1 to 3 parts of cortex moutan, 1 to 3 parts of sandalwood and 0.5 to 1 part of borneol. The compound antipruritic ointment has the effects of cooling, relieving itching, detoxifying and diminishing swelling, and is used for treating itching and eczema dermatitis itching caused by biting of various small insects such as mosquitoes and the like. According to the compound antipruritic ointment disclosed by the invention, a plurality of components are in synergistic interaction, so that a multi-target and multi-layer treatment effect is realized. The traditional Chinese medicine composition can be used for cooling, relieving itching, detoxifying and diminishing swelling from the source while quickly relieving itching, and a comprehensive and effective solution is provided for itching.

The invention discloses a traditional Chinese medicine composition for treating type 2 diabetes and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from, by weight, 11-15 parts of radix acanthopanacis semticosi, 5-15 parts of male silkworm moth, 7-17 parts of white ginseng, 5-11 parts of rhizoma polygoni cuspidati, 15-25 parts of rhizoma coptidis, 1-5 parts of cortex cinnamomi, 11-15 parts of fructus ligustri lucidi, 11-15 parts of common fenugreek seed, 7-17 parts of lithocarpus litseifolius, 3-7 parts of raw radix astragali and 1-3 parts of wild lucid ganoderma. , 3-9 parts of tribulus terrestris and 11-17 parts of nigella nigra seeds. The traditional Chinese medicine composition has the effect of balancing and stabilizing blood sugar, is short in treatment course, quick in effect and free of toxic and side effects, and has an excellent curative effect on treating diabetic complications.

The invention discloses a phlebitis treatment gel containing a coptis chinensis-wine-treated rhubarb compound component and a preparation method of the phlebitis treatment gel. The active ingredients of the gel are coptis chinensis, rheum officinale and wine-treated rheum officinale in a mass ratio of (1.5-2.5): (1.5-2.5): 1, preferably 2: 2: 1. Lavender essential oil, tea tree essential oil, folium eucalypti essential oil and vinegar frankincense, radix trichosanthis and other traditional Chinese medicine auxiliary materials are used as auxiliary materials. The preparation method comprises the following steps: extracting twice with ethanol, mixing extracting solutions, adding borneol, menthol and essential oil, and finally gelling with carbomer. The phlebitis gel can be independently used or combined with indometacin to form dual-channel anti-inflammation, and the defects of skin atrophy, toxicity accumulation and the like of traditional phlebitis gel are overcome. The traditional Chinese medicine composition is clinically expanded and applied to first-stage pressure sores (without skin damage), acnes and mosquito bites, red and swollen of the first-stage pressure sores fade away within 3-5 days, red and swollen of the acnes are relieved by more than or equal to 60% when the traditional Chinese medicine composition is combined with oral medicine for 48 hours, the itching relieving effect on the mosquito bites is less than or equal to 30 minutes, and the curative effect on phlebitis is remarkably superior to that of 50% magnesium sulfate (Plt;

The invention discloses a traditional Chinese medicine compound preparation for treating insomnia and a preparation method thereof, the traditional Chinese medicine compound preparation is prepared from the following raw materials or alcohol and water of the following raw materials or water extract or honey-processed paste: 15-30g of lily, 15-30g of lucid ganoderma, 15-90g of vine of multiflower knotweed, 30-60g of cortex albiziae, 30-60g of nacre mother of pearl, 6-15g of coptis chinensis, 15-30g of spina date seed, 30-60g of poria with hostwood, 6-15g of polygala tenuifolia and 30-60g of magnetite. The preparation method comprises the following steps: uniformly mixing 30-60 g of lapis chloriti, 30-60 g of ligusticum wallichii, 10-15 g of schisandra chinensis, 3-10 g of cinnamon, 15-30 g of salvia miltiorrhiza, 30-60 g of oyster, 15-30 g of platycladi seed, 15-30 g of corydalis tuber and 15-30 g of rhizoma anemarrhenae with alcohol or water or refining honey to prepare paste, and preparing the paste into a required dosage form. The traditional Chinese medicine composition has the beneficial effects that after scientific and reasonable compatibility and preparation, the medicine effect has a synergistic effect, and the traditional Chinese medicine composition has the effects of nourishing yin, clearing heat, calming the heart and soothing the nerves and is used for treating insomnia caused by fire excess from yin deficiency and liver depression.

The application provides a traditional Chinese medicine compound medicine composed of Coptis chinensis, Astragalus membranaceus, Panax notoginseng and Rehmannia glutinosa and application thereof in preventing and treating diabetes and diabetes complications, and experimental results show that the compound medicine has good prevention and treatment effects on diabetes and various diabetes complications such as diabetic heart disease, diabetic kidney disease and diabetic retinopathy.

The invention provides a culture method and an acclimatization and transplantation method for coptis chinensis test-tube plantlets, and belongs to the technical field of plant tissue culture. The method comprises the following steps: (1) disinfecting a coptis chinensis explant, inoculating the disinfected coptis chinensis explant into an MS basal culture medium, and culturing to obtain a sterile seedling; (2) inoculating the aseptic seedlings into an adventitious bud culture medium for adventitious bud culture to obtain adventitious buds; (3) inoculating the adventitious buds into a proliferation culture medium for proliferation culture to obtain proliferation seedlings; and (4) inoculating the proliferation seedlings into a rooting culture medium for rooting culture to obtain the coptis chinensis test-tube plantlets. When the adventitious bud, proliferation and rooting culture medium is used for culturing the coptis chinensis test-tube plantlet, the proliferation coefficient of the test-tube plantlet reaches 3.0, the rooting rate reaches 96.3%, and the survival rate of acclimatization and transplantation reaches 91.5% through seedling acclimatization and transplantation. The culture method provided by the invention is used for preserving the germplasm resources of the coptis chinensis, and provides a basic guarantee for the germplasm improvement of the subsequent medicinal material coptis chinensis.

This invention discloses a traditional Chinese medicine composition for reversing type 2 diabetes and its preparation method, belonging to the field of traditional Chinese medicine technology. It comprises the following raw materials in parts by weight: Astragalus membranaceus 25-35 parts, Rehmannia glutinosa 20-30 parts, Trichosanthes kirilowii 15-25 parts, Anemarrhena asphodeloides 10-20 parts, Coptis chinensis 8-15 parts, Salvia miltiorrhiza 15-25 parts, Ligusticum chuanxiong 8-15 parts, Paeonia lactiflora 10-20 parts, Pueraria lobata 20-30 parts, Atractylodes lancea 10-20 parts, Poria cocos 15-25 parts, Alisma plantago-aquatica 10-20 parts, Ophiopogon japonicus 15-25 parts, Schisandra chinensis 5-15 parts, and Glycyrrhiza uralensis 3-10 parts. This invention strictly follows the principles of traditional Chinese medicine's principal, assistant, adjuvant, and guide herb combination, comprehensively addressing the four methods of invigorating qi and nourishing yin, clearing heat, resolving blood stasis, and eliminating turbidity. It regulates the body's metabolism from the root cause, significantly controlling blood sugar and improving insulin resistance, while also protecting pancreatic function, thus solving the problems of single herb combinations and limited efficacy in traditional Chinese medicine.

This invention relates to a traditional Chinese medicine preparation for treating functional dyspepsia and its preparation method. The traditional Chinese medicine preparation is made from the following raw materials in parts by weight: Pinellia ternata 200-781 parts, Coptis chinensis 50-365 parts, Scutellaria baicalensis 100-521 parts, Zingiber officinale 150-625 parts, Panax ginseng 50-313 parts, Glycyrrhiza uralensis 100-417 parts, Ziziphus jujuba 150-625 parts, and Citrus aurantium 150-521 parts. The traditional Chinese medicine preparation of this invention has a good therapeutic effect on functional dyspepsia, and the preparation method of this traditional Chinese medicine preparation is simple and suitable for large-scale production and promotion.

The invention discloses a tea yellow liquid as well as a preparation method and application thereof, and belongs to the field of agricultural additives. The preparation process of the tea yellow liquid comprises the following steps: drying and crushing raw materials, adding water for dissolving out, centrifuging to obtain a mixed fine suspension, finally adding an enzyme inhibitor, and carrying out secondary sanding and dilution to obtain the tea yellow liquid. The tea yellow liquid is prepared from, by mass, 7-99.5% of tea saponin liquid, 0.5-93% of coptis chinensis liquid and the balance water, tea saponin active ingredients contained in the tea saponin liquid can remarkably reduce the surface tension of pesticide liquid, the tea saponin active ingredients cooperate with macromolecular substances such as polysaccharide in the coptis chinensis liquid to form a biomass affinity film, the spreadability and adsorbability of the pesticide liquid are greatly improved, and the pesticide effect is improved. Therefore, the content of the pesticide liquid in unit area is increased, the application amount of the pesticide is greatly reduced, and pesticide residues caused by excessive application are reduced.

The invention relates to the technical field of duck breeding, in particular to a traditional Chinese medicine composition and application thereof in treating riemerella anatipestifer. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 3-12 parts of rhizoma coptidis, 3-12 parts of cortex phellodendri, 5-20 parts of cortex fraxini, 8-30 parts of dandelion, 3-12 parts of radix saposhnikoviae, 5-20 parts of fried fructus aurantii, 8-30 parts of fried rhizoma atractylodis macrocephalae and 3-12 parts of liquorice. The novel traditional Chinese medicine composition is obtained through research, the traditional Chinese medicine composition with a better treatment effect on riemerella anatipestifer disease is obtained through synergistic compatibility of all the components, and the traditional Chinese medicine composition has important application value.

The invention relates to a purification and application method of a self-assembled supramolecular substance based on a radix puerariae, scutellaria baicalensis, coptis chinensis and honey-fried licorice root decoction, which comprises the following steps: proportioning radix puerariae, scutellaria baicalensis, coptis chinensis and honey-fried licorice root, adding water, decocting to obtain a GQD decoction, sequentially carrying out ultrafiltration and alcohol precipitation treatment on the supernatant of the GQD decoction, volatilizing the obtained supernatant, redissolving, and freeze-drying to obtain the self-assembled supramolecular substance, and purifying to obtain the self-assembled supramolecular substance based on the self-assembled supramolecular substance based on the radix puerariae, scutellaria baicalensis, coptis chinensis and honey-fried licorice root decoction. The compound is further used for preparing anti-inflammatory and anti-UC drugs; according to the invention, the anti-UC characteristic of the traditional Chinese medicine composition is utilized to recover intestinal flora with UC disorder and repair damaged intestinal barriers, meanwhile, core pharmacodynamic substances are reserved to the greatest extent, other irrelevant or harmful impurities can be reduced, and the traditional Chinese medicine composition is suitable for separating and purifying a nano-scale supramolecular compound with biological activity in a traditional Chinese medicine decoction to improve the curative effect and reduce toxic and side effects, so that the traditional Chinese medicine composition is suitable for clinical application. And the intestinal micro-ecology and mucous membrane barrier function can be repaired.

The invention discloses application of berberine or berberine hydrochloride in preparation of drugs for resisting HPV infection related diseases. Preferably, the berberine is an extract of natural plants such as coptis chinensis, golden cypress, berberis poiretii schneid or Chinese mahonia. According to the application, the new application of the berberine or the hydrochloride thereof in the aspect of resisting the HPV virus is expanded, and the berberine or the hydrochloride thereof is used for preparing the preparation for resisting the HPV infection, so that diseases related to the HPV infection can be prevented or treated, and the virus is promoted to become negative. As a natural plant extract, berberine is high in safety and not easy to generate drug resistance, and has important clinical significance when being used for preparing Chinese patent medicine products for resisting HPV infection.

This invention discloses a Zhishu Yangwei tablet for chronic gastritis and its granule dry-compression tableting process, relating to the field of traditional Chinese medicine preparation technology. The Yangwei tablet is made from the following raw materials in parts by weight: Codonopsis pilosula 35-45 parts, stir-fried Atractylodes macrocephala 18-22 parts, Poria cocos 18-22 parts, Glycyrrhiza uralensis 8-12 parts, Amomum villosum 18-22 parts, Lindera strychnifolia 18-22 parts, Salvia miltiorrhiza 45-55 parts, roasted Aucklandia lappa 18-22 parts, Paeonia lactiflora 18-22 parts, stir-fried Citrus aurantium 18-22 parts, Magnolia officinalis 28-32 parts, Lilium brownii 35-45 parts, and stir-fried chicken gizzard lining 18- 22 parts, dried plum 45-55 parts, Coptis chinensis 8-12 parts, hawthorn 35-45 parts, magnesium stearate 5-7 parts, sucrose 28-32 parts; This invention uses low-temperature dynamic extraction technology to replace the traditional high-temperature decoction process, effectively reducing the decomposition loss of heat-sensitive active ingredients such as tanshinone IIA and ursolic acid, and improving the bioavailability of the drug. It also uses membrane concentration and spray drying technology to replace the traditional atmospheric pressure concentration and oven drying process, shortening the production cycle, reducing energy consumption, and avoiding the degradation of active ingredients caused by prolonged heating of materials.

The invention discloses a traditional Chinese medicine composition for treating middle-jiao type diabetes as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 15-30 parts of herba eupatorii, 10-20 parts of radix astragali, 8-15 parts of radix codonopsis, 1-3 parts of gypsum, 6-12 parts of radix rehmanniae preparata, 6-12 parts of radix rehmanniae recen, 9-15 parts of Chinese yam, 18-30 parts of radix trichosanthis, 12-20 parts of rhizoma anemarrhenae, 12-20 parts of radix ophiopogonis, 9-15 parts of dendrobe, 9-15 parts of radix polygonati officinalis, 3-6 parts of safflower, 3-6 parts of coptis chinensis, 9-15 parts of radix scrophulariae, 9-15 parts of dogwood, 6-10 parts of liquorice and 9-15 parts of seville orange flower. , 9-15 parts of loquat flower, 6-12 parts of penthorum chinense pursh and 6-12 parts of angelica keiskei. The traditional Chinese medicine composition is suitable for nourishing yin, moistening the lung, clearing the stomach, clearing heat, moistening dryness and promoting the secretion of saliva or body fluid, has a positive regulation effect on blood sugar and blood fat of diabetes patients, and is used for middle-digestion diabetes.

This invention discloses a pharmaceutical composition and its preparation method for treating atrophic gastritis, precancerous lesions of the stomach, and stomach cancer, belonging to the field of traditional Chinese medicine preparation technology. The pharmaceutical composition is prepared by a specific two-step microbial fermentation process using Astragalus membranaceus, Hericium erinaceus, Curcuma zedoaria, Actinidia chinensis root, Camptotheca acuminata fruit, Hedyotis diffusa, Coptis chinensis, Taraxacum mongolicum, Viola yedoensis, Corydalis yanhusuo (processed with vinegar), Phellodendron chinense, Solanum nigrum, Scutellaria baicalensis, Panax notoginseng, Zingiber officinale, Piper cubeba, Cuttlebone, Fritillaria thunbergii, roasted soybean, and red yeast rice. This invention significantly improves the bioavailability of the active pharmaceutical ingredients through the synergistic effect of the multifunctional groups of traditional Chinese medicine and the enhanced effect of microbial fermentation. It can systematically reverse gastric mucosal atrophy and intestinal metaplasia, effectively improve microcirculation, and inhibit Helicobacter pylori, while also exhibiting good safety. This provides a novel and effective treatment for the aforementioned gastric diseases.

The application discloses a traditional Chinese medicine composition for treating heart failure and a preparation method thereof, and relates to the field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from red ginseng, Coptis chinensis, trichosanthes peel, earthworm, Rhodiolae, Ganoderma lucidum spore powder, Radix Polygoni Multiflori, Prunella vulgaris, prepared licorice and cassia twig. The traditional Chinese medicinal materials are soaked and then decocted, the filtrate is collected, filtered, concentrated, and then the extract is obtained, and the Ganoderma lucidum spore powder is added to prepare the traditional Chinese medicine composition. The composition is prepared according to the compatibility principles of tonifying deficiency and reducing excess, and regulating cold and heat, and can accurately match the syndrome type of yangqi deficiency, phlegm-heat and blood stasis blocking and collateral damage and yin exhaustion, thereby significantly improving the ejection fraction preserved heart failure composite syndrome type of chronic heart failure.

The invention discloses a medicinal moxa composition for preventing and treating atherosclerosis and suppurative bacterial infection co-disease. The medicinal moxa composition comprises coptis chinensis, radix rehmanniae, polygala tenuifolia, juncus effuses and moxa. The medicinal folium artemisiae argyi composition disclosed by the invention can be used for effectively preventing and treating atherosclerosis and skin suppurative bacterial infection co-diseases through a multi-target synergistic effect. The medicinal moxa composition has the core effects of clearing away heart-fire, inducing diuresis for treating stranguria and promoting blood circulation to remove meridian obstruction, and forms a complete treatment system which uses cold and warm as well as treats both symptoms and root causes by purging fire for removing toxin through coptis chinensis, clearing heat and cooling blood through radix rehmanniae, soothing nerves and promoting intelligence through polygala, inducing diuresis and conducting heat downward movement through juncus effuses and combining moxa floss for warming and dredging meridians, eliminating cold to stop pain, resisting bacteria and diminishing inflammation. By inhibiting inflammatory factors, regulating epithelial cell proliferation and reaction to oxidative stress, regulating fluid shear force, atherosclerosis and Kaposi sarcoma-related herpesvirus infection-related pathways and other mechanisms, the medicinal folium artemisiae argyi composition realizes synergistic prevention and treatment of atherosclerosis and skin infection, and provides a basis for co-disease treatment.

The invention relates to a fermented traditional Chinese medicine composition for preventing and treating piglet viral diarrhea as well as a preparation method and application thereof, and relates to the technical field of livestock breeding. The feed is prepared by taking traditional Chinese medicine components as basic raw materials and adding probiotics for fermentation, and the traditional Chinese medicine components comprise the following raw materials in parts by weight: 0.5-1.5 parts of cardamine violifolia dry powder, 5-15 parts of Chinese pulsatilla root, 10-20 parts of coptis chinensis, 10-20 parts of golden cypress, 10-20 parts of ash bark, 4-8 parts of turmeric, 6-10 parts of pumpkin seeds and 4-8 parts of a ginkgo leaf extract feed additive. Through cooperation of multiple components, the immunity and antioxidant functions of the body are enhanced, the structural integrity of the intestinal tract is maintained, piglet diarrhea caused by PEDV infection is effectively relieved, and growth and development of the piglet are promoted; local specialty crops are selected as medicines, and theoretical basis and practical reference are provided for deep processing of local genuine medicinal materials and PED prevention and control.

This invention belongs to the field of veterinary drug technology, specifically a method for preparing a stress-relieving oral liquid. The specific steps of this method are as follows: weighing the Chinese herbal medicine slices, soaking and pre-treatment, heating and extraction, filtering the extract, vacuum concentration, and preparing the oral liquid. This method uses a low-temperature vacuum concentration process to prepare a Gardenia jasminoides extract after the Chinese herbal medicine extraction, avoiding the destruction of the active ingredients by high temperatures and maximizing the retention of the effective active substances of Coptis chinensis, Scutellaria baicalensis, and Gardenia jasminoides. In the subsequent compounding process, pharmaceutical-grade anhydrous glucose and sodium salicylate are selected as excipients to form a stable and homogeneous system with the compound small molecule peptides and the Gardenia jasminoides extract. This system is free of easily separated, precipitated, or turbid components, effectively tolerating the high temperature and humidity environment of farms, the bumpy rides of long-distance transportation, and the requirements of long-term storage, preventing rapid degradation of the active ingredients of the Chinese herbal medicine, and ensuring the stable efficacy of the oral liquid.

The invention relates to the technical field of traditional Chinese medicine preparations, and provides a traditional Chinese medicine composition with acid inhibiting and esophagus protecting effects, which is prepared by compatibility of the following raw material medicines in parts by weight: 6-12 parts of coptis chinensis; 2 to 6 parts of fructus evodiae; 15 to 25 parts of cuttlebone; 10 to 20 parts of inula flower; 15 to 25 parts of ruddle; 12-20 parts of radix paeoniae alba; 8-15 parts of dried orange peel; and 6-10 parts of licorice root. According to the traditional Chinese medicine composition disclosed by the invention, through synergistic compatibility of multiple raw material medicines, the comprehensive efficacy of inhibiting acid, protecting mucous membranes and regulating power is realized, related symptoms are mildly relieved, no adverse reaction exists, and the traditional Chinese medicine composition is suitable for long-term conditioning. The standardized preparation process improves the extraction rate of effective components, ensures the stable and consistent curative effect of the product, overcomes the problems of extensive process and unstable quality of the traditional Chinese medicine preparation, and is suitable for different people, convenient to take, high in compliance, easily available in raw materials, controllable in cost and suitable for industrial production and clinical popularization.

The invention relates to the technical field of traditional Chinese medicinal material extraction, and discloses traditional Chinese medicinal material extract pressure steam sterilization equipment which comprises a tank body, a feeding port is formed in the top of the tank body, a hydraulic motor is fixedly connected to the top of the tank body, a discharging pipe is fixedly connected to the bottom of the tank body, and a steam pipe penetrates through the tank body. The stirring mechanism is arranged in the tank body and extends into the tank body, and a mixing mechanism is arranged in the tank body; the mixing mechanism comprises a vertical shaft, a sliding sleeve and a first sliding groove, the first stirring rod rotates and moves up and down in a reciprocating mode, steam is evenly introduced into the tank body and makes full contact with a coptis chinensis extracting solution, high-temperature sterilization is conducted, the sterilization effect of the steam on the coptis chinensis extracting solution is improved, and the practicability is high. A coptis chinensis extracting solution in the tank body continuously flows through the rotation of the first stirring rod, the contact uniformity of steam and the coptis chinensis extracting solution is further improved, and sediments on the inner wall of the tank body can be scraped by a scraping plate and are prevented from influencing the sterilization effect and the equipment performance.

This invention provides a traditional Chinese medicine composition for treating skin trauma, its preparation method, and its application, relating to the field of traditional Chinese medicine technology. The traditional Chinese medicine composition of this invention comprises the following raw materials in parts by weight: Astragalus membranaceus 20-30 parts, Piper kadsura vine 20-30 parts, Dragon's blood 10-20 parts, Rheum palmatum 3-8 parts, Coptis chinensis 3-8 parts, Phellodendron chinense 3-8 parts, Angelica sinensis 8-15 parts, Panax notoginseng 1-5 parts, Angelica dahurica 5-10 parts, Rehmannia glutinosa 5-10 parts, Scrophularia ningpoensis 3-8 parts, Aucklandia lappa 1-5 parts, Paeonia suffruticosa 5-10 parts, Rosin 3-8 parts, Vespa nidus 10-15 parts, and Carbonized human hair 1-5 parts. The various medicinal materials of this invention interact and complement each other, possessing the effects of promoting diuresis and reducing swelling, promoting tissue regeneration and detoxification, anti-inflammatory and analgesic effects, and activating blood circulation and removing blood stasis. It can reduce tissue swelling and redness, effectively prevent infection of burn wounds, and improve wound healing speed. It has significant therapeutic effects on skin trauma caused by burns and scalds, with no toxic side effects.

The invention discloses an external application medicine formula for acute pancreatitis, and belongs to the field of traditional Chinese medicine preparation formulas, and the external application medicine formula for acute pancreatitis is prepared from the following raw materials in parts by weight: 1-2 parts of honeysuckle, 1-2 parts of wild chrysanthemum flower, 1-2 parts of dandelion, 1-2 parts of herba violae, 1 part of scutellaria baicalensis, 1 part of coptis chinensis, 1 part of raw rhubarb, 1 part of raw liquorice, 1 part of radix paeoniae rubra and 1 part of mangnolia officinalis. The traditional Chinese medicine composition can effectively reduce peripancreatic exudation and promote gastrointestinal motility, so that the symptoms of abdominal distension and abdominal pain of a patient are relieved, meanwhile, pancreatic microcirculation can be improved, disease recovery is facilitated, the preparation process is simple and easy to understand, complex equipment is not needed, and the production cost is greatly reduced.

Helicobacter pylori (HP) is a chronic bacterium that infects the gastric mucosa. It is widespread in the general population, with an infection rate between 55% and 70%. HP is closely related to gastric ulcers and gastritis. Western medicine treatment for HP infection is relatively complex, including bismuth substituents and proton pump inhibitors plus two antibiotics. Gastric ulcers and gastritis are common digestive system diseases. Compound 1, "Exterminate the Ghost," is a traditional Chinese medicine composition mainly composed of Coptis chinensis, plus Scutellaria baicalensis and Fraxinus chinensis, which can eradicate HP. Compound 2, "Ulcer Relief," is a traditional Chinese medicine composition mainly composed of Coptis chinensis, plus Rheum palmatum and Bletilla striata, which can cure gastric ulcers. Compound 3, "Gasitis Relief," is a traditional Chinese medicine composition mainly composed of Coptis chinensis, plus Glycyrrhiza uralensis or Taraxacum mongolicum, made into a tea bag, which can cure chronic gastritis.

This invention provides a compound drug for treating melioidosis, its preparation method, and its application. The drug comprises active components of traditional Chinese medicine, a bioactive preparation, and a pharmaceutically acceptable carrier. The active components of traditional Chinese medicine are primarily extracts of Scutellaria baicalensis, Coptis chinensis, Fagopyrum dibotrys, and Polygonum cuspidatum. The bioactive preparation includes polymyxin B, homoserine lactonease, and recombinant human β-defensin 3. The components work synergistically to construct a comprehensive intervention system covering all pathological stages, including biofilm disruption, sterilization, anti-endotoxin activity, intracellular bacterial clearance, immune regulation, and tissue repair. This system can effectively disrupt bacterial biofilms, kill multidrug-resistant strains, neutralize endotoxins, and eliminate latent intracellular bacteria, addressing the core pain points of existing melioidosis treatments, such as strong drug resistance, significant toxic side effects, and high recurrence rates. The preparation process of this invention is carried out under low-temperature and sterile conditions throughout, which fully preserves the stability of the active ingredients, making it suitable for industrial production. The drug can be prepared in various dosage forms, covering all clinical subtypes of melioidosis, and possesses clinical application value and promising prospects for widespread application.

The application discloses a spleen-targeting nanoassemblies of active ingredients of Sanhuang Xiexin Decoction, a preparation method and application thereof, and belongs to the technical field of biological medicine, and comprises spleen-targeting exosomes and nanoassemblies containing active ingredients of Sanhuang Xiexin Decoction, wherein the nanoassemblies containing active ingredients of Sanhuang Xiexin Decoction are loaded on the spleen-targeting exosomes; and the active ingredients of Sanhuang Xiexin Decoction are three active ingredients corresponding to three traditional Chinese medicines, i.e., rhubarb, Coptis chinensis and Scutellaria baicalensis. The application has the beneficial effects that based on three key active components of Sanhuang Xiexin Decoction, the nano delivery system of the carrier-free pure medicine of three active ingredients of traditional Chinese medicine compound is developed for the first time through a chemical self-assembly technology, support is provided for the development of a new dosage form of the nano preparation of the traditional Chinese medicine compound, and the spleen immune function disorder-mediated diseases have a good targeted treatment effect.

The invention relates to an Angong bezoar pill and a preparation method thereof. The Angong bezoar pill contains 0.2 part of a bionic rhinoceros horn biological agent, 0.1 part of the bionic rhinoceros horn biological agent, 0.025 part of musk, 0.05 part of pearl, 0.1 part of cinnabar, 0.1 part of realgar, 0.1 part of coptis chinensis, 0.1 part of scutellaria baicalensis, 0.1 part of cape jasmine, 0.1 part of radix curcumae and 0.025 part of borneol for compatible use. The similarity between the core chemical components of the bionic rhinoceros horn biological agent and the natural rhinoceros horn reaches 95% or above, and the composition and content of active substances meet the drug effect requirements.

The invention discloses traditional Chinese medicine combined powder for rapidly treating various burns and scalds, and relates to the technical field of traditional Chinese medicine formulas. Traditional Chinese medicine combined powder for rapidly treating various burns and scalds is characterized in that the active ingredients of the powder comprise 6-10 parts by weight of polygonum cuspidatum, 3-9 parts by weight of coptis chinensis, 4-10 parts by weight of paris polyphylla, 6-12 parts by weight of rhizoma bletillae, 15-30 parts by weight of calcined dens draconis, 3-9 parts by weight of spar and 0.1-0.3 part by weight of pearl. The combined medicine powder has the effects of clearing away heat and toxic materials, promoting tissue regeneration, relieving pain, promoting wound repair and enhancing local microcirculation of the wound, the medicine powder generally needs to be combined with sesame oil for use, the core components of the medicine powder, namely polygonum cuspidatum and coptis chinensis, synergistically exert broad-spectrum antibacterial and antioxidant effects, and paris polyphylla and rhizoma bletillae enhance the barrier function of the wound; the calcined dens draconis and the kyanite promote activation of a calcium ion channel, and the pearl can regulate and control ordered deposition of collagen and reduce scar hyperplasia.

The invention relates to a traditional Chinese medicine compound for preventing and treating fish streptococcicosis, and belongs to the technical field of research and development of aquaculture disease prevention and control medicines and feed additives. The traditional Chinese medicine compound for preventing and treating fish streptococcicosis comprises the following effective components: coptis chinensis, ginger and Chinese dates, the mass ratio of the coptis chinensis to the ginger to the Chinese dates is (12.0-16.0): (2.0-4.0): (7.4-9.2). The formula is safe and non-toxic to fish, has a good prevention and treatment effect on fish streptococcosis, and is environment-friendly, wide in raw material source, low in price, good in biocompatibility and simple in preparation process.