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84results about How to "Recovery function" patented technology

Industrial firewall isolation method of DCS system

The invention discloses an industrial firewall isolation method of a DCS (Distributed Control System). The objective of the invention is to solve the problem that existing industrial network security protection has defects for a DCS system. According to the method, firstly, DCS architecture analysis and risk assessment are carried out, and protection key points and data flow directions are accurately determined; then, a firewall strategy fitting the characteristics of each area (such as a core control unit, an operation station and an external network interface) is customized, and mechanisms such as multiple data encryption are covered; and then firewall deployment and configuration optimization are carried out to ensure protection continuity and rule timeliness. And abnormal conditions are timely handled through a real-time monitoring and dynamic adjustment mechanism, and system recovery under a security event is guaranteed through an emergency response and backup recovery mechanism. And a regular safety drill and evaluation mechanism is arranged to continuously strengthen the protection capability. According to the method, the network security level of the DCS is comprehensively improved, stable and safe operation of industrial production is guaranteed, and the method has remarkable practical value.
Owner:YUHENG POWER STATION OF SHAANXI HUADIAN YUHENG COAL POWER CO LTD

Preparation method of zinc-dihydromyricetin nano-enzyme and application of zinc-dihydromyricetin nano-enzyme in preparation of drugs for promoting healing of diabetic wounds

The invention discloses a preparation method of a zinc-dihydromyricetin nano-enzyme and application of the zinc-dihydromyricetin nano-enzyme in preparation of drugs for promoting healing of diabetic wounds, and the zinc-dihydromyricetin metal polyphenol nano-enzyme (Zn-DHM) is obtained by coordinating a metal element zinc (Zn) and a natural product dihydromyricetin (DHM) through a one-step method by taking PVP as a surfactant. The Zn-DHM nano-enzyme prepared by the invention has antioxidant property and cell proliferation and migration promoting ability, and can maintain metabolism and immune homeostasis of diabetic wounds, so that the Zn-DHM nano-enzyme can accelerate early healing of the diabetic wounds.
Owner:ANHUI MEDICAL UNIV

Guardrail breakdown van with high stable support

The invention relates to the technical field of guardrail breakdown van, and discloses a high-stable-support guardrail breakdown van which comprises a van body and a storage frame, the storage frame is fixedly connected to the middle of the van body, a telescopic plate is slidably connected to the inner wall of the storage frame, and a guide rail is rotatably connected to the middle of the side, away from the storage frame, of the telescopic plate; a hydraulic hammer head is slidably connected to the middle of the inner wall of the guide rail, through the arrangement of the first-aid repair and exchange mechanism, in the process of piling installation of a guardrail pile body, a damaged guardrail can be repaired in a targeted and selected mode, first-aid repair and trimming are correspondingly conducted according to the guardrail damage degree, and the safety of the guardrail is improved. And the trimmed guardrail is cleaned and maintained, and finally the trimmed guardrail is returned to a position required by site construction for use, so that the waste guardrail does not need to be collected and transferred, the overall first-aid repair time is shortened, and related road facilities can be recovered and used in time.
Owner:XUZHOU HENGXING JINQIAO MACHINERY TECH

Ecological restoration method for waste alum mine land

The invention discloses an ecological restoration method for waste alum mine land. The ecological restoration method comprises the following steps: (1) soil improvement; (2) suitable plant species are selected, vetiver grass is planted in herbaceous species, neoleucaena leucocephala and broussonetia papyrifera are planted in arbor species, and lespedeza speciosa is planted in shrub species; (3) firstly adopting grass planting belts to fix the soil, selecting vetiver grass seedlings for planting, and planting one grass belt every 10 meters along the contour line to fix the soil; and planting arbors, shrubs and other herbaceous plants among the planting belts. The invention has the following advantages: 1, degraded soil can be repaired and improved, soil functions are recovered, and further degradation of land is prevented; 2, the living environment of other species is locally improved, and water and soil loss is prevented; and 3, the water storage function of the waste land is improved, and the underground root system and the overground stem leaves have mechanical reinforcement, anchoring and supporting effects and obvious water and soil conservation and ecological slope protection functions of intercepting rainfall, inhibiting surface runoff, weakening splash erosion and the like.
Owner:LISHUI VOCATIONAL & TECHNICAL COLLEGE

In-vitro amplification culture method of NK (Natural Killer) cells

The invention belongs to the technical field of immune cell culture, and particularly relates to an in-vitro amplification culture method of NK cells. The amplification method comprises the steps of CD16 pretreatment, plasma inactivation, lymphocyte separation and multi-stage fluid infusion. The preparation method comprises the following steps: pretreating CD16 in a T75 culture flask, promoting attachment and activation of NK cells, simulating a natural activation state, improving proliferation efficiency, treating whole blood and inactivating plasma to eliminate immunosuppressive factors, reserving nutritional ingredients, supporting amplification of the NK cells, enriching the NK cells through a lymphocyte separating medium, removing impurities and improving purity, mixing an RPMI-1640 culture medium with a solution A, and culturing for 12-24 hours at a high temperature; oK432 and IL-15 are added, the microenvironment is optimized, growth of the NK cells is remarkably promoted, liquid supplementing operation and bottling and bagging are carried out for multiple times, sufficient space and nutrition are provided, the cells are gradually transferred into a serum-free culture medium, and the cell safety and clinical application potential are improved.
Owner:潍坊吉涛医学科技有限公司 +1

Method for regulating neurotoxic reactive astrocytes, regulator and application

TMEM164 and the like can prevent and inhibit the induced activation of neurotoxic reactive astrocytes and neuron death in neurodegenerative diseases. The present invention relates to the field of neuroscience, in particular the medical treatment of neurodegenerative diseases. TMEM164, SOC18, CAPN15 and the like are identified as early reaction regulatory factors of neurotoxic astrocyte reactivity, and it is found that for example, TMEM164 overexpression can prevent induced activation of neurotoxic reactive astrocytes and neuron death in mouse and human astrocytes, as well as in an inflammation-induced PD mouse model and a 5XFAD mouse model; therefore, a basis is provided for treatment of neurodegenerative diseases related to neurotoxic reactive astrocytes.
Owner:CENT FOR EXCELLENCE IN BRAIN SCI & INTELLIGENCE TECH CHINESE ACAD OF SCI

Sea-buckthorn oat peptide as well as preparation and application thereof

The invention provides hippophae rhamnoides oat peptide as well as preparation and application thereof. According to the invention, three active peptides are separated and purified from oats for the first time, and on the basis of the active peptides, wall-broken oat powder, sea-buckthorn powder, Chinese yam powder and three prebiotics are combined to obtain the sea-buckthorn oat peptide. The hippophae rhamnoides oat peptide can restore the blood sugar storage and transfer functions by reducing the blood sugar content of diabetic patients and increasing the insulin content of the diabetic patients, and provides reference significance for treatment of diabetes mellitus.
Owner:JIANYUAN (GUANGZHOU) HEALTH CULTURE COMM CO LTD

Overload protector switch

The utility model relates to the field of electric appliance protection equipment, and discloses an overload protector switch which comprises an overload protector shell, a circuit break protection mechanism is arranged in an inner cavity of the overload protector shell, and a protector switch is arranged on the front side face of the overload protector shell. Two symmetrical anti-loosening devices are arranged at the corresponding upper and lower ends of the front side surface of the overload protector shell, two wiring mounting grooves are formed in each of the upper and lower sides of the overload protector shell, the wiring devices are arranged in the wiring mounting grooves, and the device adopts a modular design, so that wiring, disassembly and maintenance are facilitated, and the overload protector is convenient to use. Electrical equipment is efficiently and stably protected, downtime is reduced, functions are quickly recovered, and safe and stable operation of the equipment is ensured.
Owner:SHENZHEN LILIANXIN ELECTRONICS CO LTD

Preparation and application of HVC NPs for the diagnosis and treatment of Parkinson's disease

This invention discloses a method for preparing HVC NPs for the diagnosis and treatment of Parkinson's disease and their applications. The probe HV in the HVC NPs responds to H2O2 and viscosity, utilizing near-infrared fluorescence imaging capabilities to achieve real-time monitoring of Parkinson's disease biomarkers, helping us better understand the occurrence and development of Parkinson's disease. With the assistance of RVG29, the HVC NPs effectively cross the blood-brain barrier. The curcumin within them can reduce cell apoptosis, lower oxidative stress levels, scavenge excess reactive oxygen species, combat inflammation, and reduce α-synuclein aggregation, demonstrating effective anti-Parkinson's disease effects at the cellular and experimental animal levels. This nanomaterial provides a new strategy for integrated research on the diagnosis and treatment of Parkinson's disease.
Owner:SHANXI MEDICAL UNIV

Hollow fiber preparation equipment

The invention relates to the technical field of fiber manufacturing equipment, and discloses hollow fiber preparation equipment which comprises preparation equipment and a supporting frame, a switching piece is arranged on the supporting frame, two spinneret plates are installed on the switching piece, the switching piece comprises a motor driving the switching piece to rotate, and the two spinneret plates are arranged on the supporting frame. A pipeline on the preparation equipment is connected with one of the spinneret plates, the supporting frame is provided with an inserting and pulling piece, the pipeline on the preparation equipment is connected with the inserting and pulling piece, and the inserting and pulling piece is used for connecting and separating the pipeline on the preparation equipment and the spinneret plates; the problems that existing hollow fiber preparation equipment mostly adopts a single spinneret plate design, and once the spinneret plate is blocked, shutdown is often needed for manual cleaning, so that the maintenance cost is increased, and the continuity and the production efficiency of a production line are seriously influenced are effectively solved.
Owner:ZHEJIANG TEXTILE & FASHION COLLEGE +1

Use of casein hydrolysate compositions to improve aging

PendingCN122498654AImprove purposeProtect from pathological damage
This invention belongs to the field of functional substance research, specifically relating to the use of casein hydrolyzed peptide compositions in improving aging, and more specifically to their use in the preparation of products for improving aging. The casein hydrolyzed peptide compositions are obtained by enzymatically hydrolyzing casein solution using serine protease and flavor protease. Furthermore, in the casein hydrolyzed peptide compositions, the relative strength of total functional peptides is above 25%, the relative strength of casein phosphopeptides is above 9%, and the relative strength of functional peptides other than casein phosphopeptides is above 11%. This casein hydrolyzed peptide composition can effectively alleviate oxidative stress caused by aging, inhibit chronic low-grade inflammation, reduce aging-related damage to vital organs such as the liver and brain, improve the body's immune function, and improve the external phenotype of aging, thereby comprehensively exerting an anti-aging effect.
Owner:EAST UNIV OF HEILONGJIANG +1

Photosensitizer chimera targeting PD-L1 protein as well as preparation method and application of photosensitizer chimera

The invention relates to a PD-L1 protein targeted photosensitizer chimera as well as a preparation method and application thereof. The photosensitizer chimera is of an X-R-G structure, X is a photosensitizer unit, R is a connecting arm, G is a polypeptide unit targeting PD-L1 protein, a photosensitizer is a porphyrin photosensitizer, and the excitation light wavelength of the photosensitizer is gt; the wavelength is 550nm; the molar absorption coefficient gt at the maximum absorption wavelength after the wavelength of 550 nm; 1000 M <-1 > cm <-1 >; the quantum yield of the triplet state is gt; 0.01, 0.01; the connecting arm is selected from the following structural formula: # imgabs0 #, the amino side of the connecting arm is connected with the photosensitizer unit, the carboxyl side of the connecting arm is connected with the polypeptide unit, and n is an integer of 0-50; the binding constant of the polypeptide and h-PD-L1 is lt; and 20 [mu] M. According to the photosensitive chimera disclosed by the invention, combined treatment based on immune checkpoint blocking and cytotoxic effects induced by photodegradation of PD-L1 protein in PD-1 / PD-L1 can generate immune response stronger than single treatment, and the photosensitive chimera has great potential in the aspect of enhancing anti-tumor treatment.
Owner:PEKING UNIV

Aero-engine turbine blade crown repairing material and repairing method thereof

According to the aero-engine turbine blade crown repairing material and repairing method, the selected cladding powder material and the blade raw material GH105 are similar in performance, the melting temperature and the density of the cladding powder material and the blade raw material GH105 are close, the content of the selected powder material AI and Ti is low, the material welding performance is good, and cracks and other defects are not prone to being generated. A series of repairing processes are set based on the repairing material, and each step aims at recovering the functions of the blade and prolonging the service life of the blade from preliminary grinding to defect removal, heat treatment to material performance improvement, laser cladding repairing and final finishing. Through a series of treatments, the damaged blade can be repaired, the use performance can be recovered, and the damaged blade can be reinstalled for use.
Owner:AECC AVIATION POWER CO LTD

Method for knocking down ubiquitin-specific peptidase 7 protein and application thereof

PendingCN122503448AImprove inflammationrecovery functionApoptosisIschemic cardiomyopathy
The application discloses a method and application of knocking down ubiquitin-specific peptidase 7 protein, and belongs to the field of biological medicine. The method for knocking down the USP7 protein comprises: specifically inhibiting the expression of USP7 in endothelial cells through gene intervention, and the gene intervention means comprises shRNA, siRNA or recombinant virus carrier-mediated USP7 expression down-regulation. Further provided is a USP7 knockdown reagent for preparing a drug for treating endothelial cell inflammation or a cardiovascular disease, in particular, the USP7 knockdown reagent is a USP7 knockdown virus carrier containing a Cdh5 promoter; the cardiovascular disease comprises heart failure, myocardial infarction or ischemic cardiomyopathy. The application specifically knocks down the expression of USP7 in endothelial cells through gene intervention, significantly improves the migration, tube formation capacity and reduces the apoptosis of the endothelial cells, repairs endothelial dysfunction, the USP7 knockdown virus carrier is used for preparing a drug for treating a cardiovascular disease, and has important clinical value.
Owner:ZHONGSHAN HOSPITAL FUDAN UNIV

Hand rehabilitation training system and training method

The invention discloses a hand rehabilitation training system and training method, and relates to the technical field of hand rehabilitation training. The finger rehabilitation device comprises a wrist fixing block, a palm fixing block and a finger fixing leather sheath, a first rotating shaft is fixedly installed outside the wrist fixing block, the finger fixing leather sheath is fixedly installed outside the hand fixing plate, and a finger rehabilitation assembly is fixedly installed outside the palm fixing block. The wrist can swing to drive the fingers to bend, the wrist swings to drive the fingers to bend, the joint motion range of the fingers is helped to be recovered, the flexibility of the fingers is improved, and through the embedded design of a first embedded protrusion and a first embedded groove matched with the embedded design of a second embedded protrusion and a second embedded groove, the flexibility of the fingers is improved. According to the detachable hand rehabilitation device, the hand rehabilitation device can be conveniently detached, so that external cleaning and subsequent maintenance of the hand rehabilitation device are facilitated, and all the components can be conveniently cleaned through the detachable design.
Owner:SUZHOU YUNDA HEALTH TECHNOLOGY CO LTD

Method for vehicle safety protection of vehicle

The invention relates to a method for vehicle safety protection of a vehicle. The invention also relates to a computer program, a device and a storage medium for this purpose.
Owner:ROBERT BOSCH GMBH

Hydraulic accident isolating valve device

The utility model relates to the technical field of hydraulic equipment, in particular to a hydraulic accident isolating valve device which comprises a main valve block, an isolating valve body is arranged on the upper portion of the main valve block, a functional valve set is installed on the upper portion of the isolating valve body, and second connecting areas meeting the ISO4401 standard are arranged on the upper surface of the main valve block and the upper surface of the isolating valve body respectively. A first connecting area is further arranged on the periphery of the second connecting area of the main valve block, if one executing mechanism and one control mechanism go wrong, under the condition that a main machine cannot stop running, the hydraulic accident isolation valve device can stop running of the single executing mechanism and the single control mechanism, and the safety of the main machine is improved. Therefore, safety of equipment and maintenance personnel is guaranteed, economic losses caused by accidental shutdown are reduced, meanwhile, when the isolating valve body breaks down, the isolating valve body can be omitted, the functional valve set is directly installed on the valve block and recovered to be used at the highest speed, efficient and green operation of a hydraulic system can be guaranteed, and practicability is improved.
Owner:HUNAN VALIN XIANGTAN IRON & STEEL CO LTD

Recycling device capable of saving water resources

The invention relates to the technical field of water resource recycling, and discloses a recycling device capable of saving water resources, the recycling device comprises a precipitation assembly, the precipitation assembly comprises a shell, the inner wall of the shell is fixedly connected with a first partition plate, and the bottom of the first partition plate is not in contact with the bottom of the inner wall of the shell. Sewage liquid levels on the two sides of the first partition plate can rise synchronously, impurities in the sewage can precipitate at the bottom of the inner wall of the shell, after the upper part of the sewage on the right side of the first partition plate is precipitated, the water is clean, and along with continuous injection of the sewage, the clean water on the upper layer can jack up the floating plate upwards and finally enters the space on the right side of the second partition plate after being filtered by the filter plate; sewage injected into the shell can fall on the left side of the first partition plate, the sewage falling on the left side of the first partition plate can enter the right side of the first partition plate only after passing through the bottom of the first partition plate, time can be provided for sewage precipitation, and therefore sewage on the upper layer of the right side of the first partition plate is always kept in a clean state.
Owner:INNER MONGOLIA AGRICULTURAL UNIVERSITY

Preparation and application of novel ultrasonic-driven nano-enzyme MOF (Hf)-Pt

The invention discloses preparation and application of a novel ultrasonic-driven nano-enzyme MOF (Hf)-Pt, the novel piezoelectric nano-enzyme MOF (Hf)-Pt is composed of UIO-66-NH2 (Hf) and an ultra-small Pt nano-enzyme and presents a regular octahedron shape, and the diameter of the novel piezoelectric nano-enzyme MOF (Hf)-Pt is 180-200 nm; the piezoelectric effect is achieved, external ultrasonic stimulation is utilized, and variable electrical stimulation is provided through piezoelectric catalysis; in addition, the composite material has the advantages of being small in size and easy to prepare, has catalase-like activity and superoxide dismutase activity at the same time, and has good biocompatibility. The MOF (Hf)-Pt is used as a novel piezoelectric catalyst, and the technical effect of treating OA is achieved by improving the enzyme catalytic activity of the nano-enzyme, relieving oxygen deficit of an inflammation part, recovering the mitochondrial function, removing excessive ROS in an inflammation tissue and promoting cartilage regeneration through the piezoelectric effect.
Owner:GUANGXI MEDICAL UNIVERSITY

Fire-resistant flame-retardant coating, cable wrapping tape and preparation method of cable wrapping tape

The invention discloses a fire-resistant flame-retardant coating, a cable wrapping tape and a preparation method thereof, and the preparation method comprises the following steps: carrying out oxygen plasma bombardment treatment on fire-resistant particles to obtain surface hydroxylated fire-resistant particles; dispersing the surface hydroxylated fire-resistant particles and carboxylated nanocellulose in a dispersion liquid according to a mass ratio of (5-15): 1 to obtain a cellulose-coated fire-resistant particle buffer solution; 26-38 parts of a buffer solution, 40-50 parts of water, 18-25 parts of ammonium polyphosphate, 12-18 parts of a charring agent, 5-8 parts of a nitrogen flame retardant, 18-25 parts of an AVE emulsion and 0.4-0.8 part of a defoaming agent are fully and uniformly mixed, and the water-soluble fireproof flame-retardant coating is obtained. A phosphorus-nitrogen flame retardant is compounded with a carbon forming agent to form a carbon shell after combustion, optimized and dispersed fire-resistant particles are uniformly inserted into the carbon shell by virtue of the expansion effect of the carbon forming agent to form fire-resistant particle aerogel, a cross-interpenetrating network structure of the fire-resistant particle aerogel and the carbon shell is formed, and a cross-interpenetrating flame-retardant layer which is flame-retardant, heat-insulating and fire-resistant is formed after a surface coating is combusted; and a stable environment is provided for normal operation of the cable.
Owner:JIANGSU WOFENG NEW MATERIAL CO LTD

Multi-head shock wave electrode structure and shock wave balloon catheter

The present invention provides a multi-head shock wave electrode structure and a shock wave balloon catheter. The multi-head shock wave electrode structure includes at least two discharge units; each discharge unit includes an emitter electrode and a corresponding intermediate electrode which are arranged at intervals and have the same extension direction, and the emitter electrodes are arranged in the intermediate electrode at intervals one by one; all the intermediate electrodes are electrically connected to each other; when the discharge end faces of all the intermediate electrodes and the discharge end faces of all the emitter electrodes are located in a conductive fluid and a potential difference is formed between the emitter electrodes of any two discharge units, shock waves are simultaneously triggered between the discharge end faces of the emitter electrodes of the two discharge units and the discharge end faces of the corresponding intermediate electrodes. The shock wave balloon catheter includes the multi-head shock wave electrode structure. The present invention solves the problem of damage caused by mechanical impact force while realizing a single effective discharge breakdown to form a large shock wave energy, and has a long service life.
Owner:RIFF MEDICAL (BEIJING) CO LTD

Alar bone body prosthesis facilitating ankle joint ligament reconstruction and neck body fixing and healing

The invention relates to the technical field of medical prostheses, and particularly discloses a talus prosthesis facilitating ankle joint ligament reconstruction and neck body fixing and healing. According to the technical scheme, a three-point fixing mode of a fixing bolt and two locking screws is adopted for connection of the talus prosthesis and the section of the talus neck of the talus prosthesis, the layout, angle and size of the fixing bolt and the locking screws are accurately controlled, mechanical distribution is optimized, the stress concentration phenomenon is reduced, a trabecula structure is further arranged on the talus prosthesis, and therefore the mechanical distribution is optimized. The stability at the initial stage of the operation is ensured, and conditions are provided for bone tissue ingrowth, so that short-term and long-term biological fixation is realized, and the postoperative recovery of a patient as soon as possible is facilitated. Besides, by reserving a tendon reconstruction channel, a tendon suture hole and a ligament suture hole, ligament reconstruction and fixation can be conveniently carried out in an operation, so that the normal biomechanical structure and function of the ankle joint are recovered, the stability of the ankle joint is enhanced, and the living quality of a patient is improved.
Owner:宋秀锋

Application of a Cav3.2 inhibitor in the preparation of drugs for treating intervertebral disc degeneration

This invention discloses the application of a Cav3.2 inhibitor in the preparation of a drug for treating intervertebral disc degeneration. Z944 can block the activation level of Cav3.2 in nucleus pulposus cells, effectively alleviating lipid metabolism disorders and cellular biological behavior disorders induced by abnormal mechanical stress, and ultimately reducing intervertebral disc degeneration. This demonstrates that Z944 is a drug with clinical application potential, which can be used to alleviate the pain and burden of patients with low back pain and improve their quality of life.
Owner:XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV

Multifunctional corrector for hemiplegic upper limbs

The invention relates to the technical field of medical instruments, in particular to a hemiplegic upper limb multifunctional corrector which comprises a wrist component, an elbow component and a shoulder component. The wearable structure is adopted, the wrist, the elbow and the shoulder of a patient are covered at the same time, and integral fixing correction and targeted treatment can be conducted on the upper limb of the affected side at the same time. The treatment assembly is arranged and can massage and release muscles by integrating air pressure massage, thermal stimulation and electrical stimulation, so that the effect of relieving muscular tension is achieved. Wherein the electrical stimulation assembly can release medium-frequency electrical stimulation signals or low-frequency electrical stimulation signals, medium-frequency electrical stimulation has the effects of activating blood, relieving swelling and pain, and low-frequency electrical stimulation can promote recovery of nervous tissue functions at corresponding positions. Therefore, nerves and muscles of a patient are treated in all directions, muscular tension of the patient is reduced, and the problem of muscle tension of the patient is avoided.
Owner:柏玉琼

Bionic traditional Chinese medicine co-assembled drug delivery system for targeting myocardial fibrosis and application of bionic traditional Chinese medicine co-assembled drug delivery system

The invention relates to a drug delivery system, and discloses a bionic traditional Chinese medicine co-assembled drug delivery system targeting myocardial fibrosis and application of the bionic traditional Chinese medicine co-assembled drug delivery system. The bionic traditional Chinese medicine co-assembled drug delivery system is mainly formed by wrapping traditional Chinese medicine co-assembled nanoparticles with a platelet membrane; the traditional Chinese medicine co-assembled nanoparticle is composed of a natural small molecule compound astragaloside derivative LS102 and Z-ligustilide, the preparation process is simple, no carrier is needed, and the cost is low. According to the bionic traditional Chinese medicine co-assembled nano drug delivery system, the particle size distribution is 190-200 nm, the potential is about-30 mV, and the bionic traditional Chinese medicine co-assembled nano drug delivery system is in a uniform sphere shape of a core-shell structure and is high in stability and biological safety. According to the invention, the blood vessel injury diseases such as myocardial infarction, myocardial fibrosis, atherosclerosis, hypertension and the like can be precisely treated by targeted damaged myocardium pair multi-component drug combined delivery by using the natural homing effect of the platelet membrane, and the application has outstanding substantive features, optimal practical effect and higher economic value.
Owner:THE AFFILIATED HOSPITAL OF TRADITIONAL CHINESE MEDICAL TO SOUTHWEST MEDICAL UNIV

Winding drum side plate rope inlet groove machining device

The utility model discloses a coiling block side plate rope inlet groove machining device which comprises a numerical control lathe and a coiling block side plate, the numerical control lathe is provided with a chuck and a slide carriage frame, the coiling block side plate is a disc-shaped part and is fixedly clamped on the chuck, a support is fixedly arranged on the slide carriage frame, a milling power head is fixedly arranged on the support, and the milling power head is provided with a milling cutter. The milling power head is provided with a milling cutter, the height of the center of the milling cutter is equal to that of the center of a spindle of the numerical control lathe, and the milling cutter is perpendicular to the winding drum side plate and can move within the diameter range of the winding drum side plate through a slide carriage frame. The milling power head is additionally arranged on the slide carriage frame of the numerical control lathe, the milling power head is provided with the milling cutter, the numerical control lathe drives the rotary motion of the winding drum side plate and the feeding motion of the milling cutter to be combined, an inner rope groove and an outer rope groove are milled according to a preset program, the machining requirement of the rope inlet groove is met, machining is automatically controlled through numerical control, and the machining efficiency is improved. The machined rope groove is good in quality and high in machining efficiency.
Owner:YICHUN JIANGTE MASCH DRIVING CO LTD

Lactobacillus rhamnosus MBP01 and composition thereof for preventing and treating irritable bowel syndrome

ActiveCN119144517BIncrease the water content of fecesImproves Structural IntegrityBacteriaAntipyreticSerum corticosteroneMicrobiological Techniques
The present invention belongs to the field of microbial technology, and specifically relates to a rhamnosus lactobacillus MBP01 and a composition thereof for preventing and treating irritable bowel syndrome. The deposit number of the rhamnosus lactobacillus MBP01 is GDMCC No: 64725. The MBP01 provided by the present invention can improve the weight loss trend of IBS model mice, increase food intake and fecal water content, alleviate damage to colon tissue, downregulate IL-1β, TNF-α, PAR-2, and serum corticosterone levels and increase IL-10 levels, while high concentrations of MBP01 can increase the expression of tight junction proteins. Therefore, MBP01 has a certain positive regulatory effect on the intestinal function of IBS model mice and can effectively prevent and treat irritable bowel syndrome.
Owner:MAYINGLONG PHARMA GROUP

Composite active dressing for nerve repair as well as preparation method and application of composite active dressing

The invention provides a composite active dressing for neural restoration and a preparation method and application thereof, and relates to the technical field of medical materials. The composite active dressing comprises a transdermal inner layer and a small extracellular vesicle slow-release outer layer, the transdermal inner layer is of a membrane-shaped structure and comprises a composite active component and a hydrogel matrix material, and the composite active component is selected from one or more of an anti-inflammatory component, a microcirculation improving component, an antioxidant component and a neurotrophic component; the small extracellular vesicle sustained-release outer layer is of a three-dimensional network structure and comprises small extracellular vesicles and a hydrogel matrix material. According to the invention, stable loading and layered deep delivery and release of the small extracellular vesicles are realized, the inflammatory response and microcirculation state of an injured part are improved, proliferation migration and remyelination of Schwann cells can be promoted, and axon regeneration and effective repair of nerve injury can also be promoted.
Owner:ZHUJIANG HOSPITAL OF SOUTHERN MEDICAL UNIVERSITY

Coordinate boring machine spring winding storage tool

ActiveCN224716178Urecovery function
The utility model discloses a kind of coordinate boring machine spring storage tool, including reel, arc cover plate and limit ring, the one end upper side of reel is provided with notch, first support ring is fixedly installed in one end of the middle part of reel in notch, another end in notch is detachably installed with second support ring, first support ring and second support ring are used for reel to be inserted, the arc cover plate is used to cover and install at notch, two the limit ring is used to be sleeved in both ends of arc cover plate, for limiting arc cover plate on reel. By the tool of the utility model, four springs can be installed into reel cylinder, so as to restore the function of coordinate boring machine equipment.
Owner:YICHANG CHANGJIANG MASCH TECH CO LTD

Box-shaped steel column foot with easily-replaced energy-consuming component

The box-shaped steel column base comprises a bottom plate (1), a box-shaped column (2), a column bottom plate (3), an arc-shaped energy consumption plate (4), an upper connecting piece (5), a lower connecting piece (6) and bolts (7). The bottom of the box-shaped column (2) is fixedly connected to the column bottom plate (3); the upper connecting pieces (5) are arranged on the four side faces of the box-shaped steel column (2). The lower connecting pieces (6) are arranged on the periphery of the bottom of the box-shaped steel column (2) and fixed to the bottom plate (1). The arc-shaped energy consumption plates (4) are arranged on the four side faces of the box-shaped steel column (2) in groups and connected with the upper connecting piece (5) and the lower connecting piece (6) through bolts (7). Damage after an earthquake is only concentrated on the arc-shaped energy consumption plate, other parts are always kept elastic, and the post-earthquake repair cost of the column foot can be greatly reduced.
Owner:HUAQIAO UNIVERSITY +2