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463 results about "Gluconolactone" patented technology

A naturally occurring polyhydroxy acid (PHA) with metal chelating, moisturizing and antioxidant activity. Gluconolactone can be produced by enzymatic oxidation of D-glucose oxidation. Its ability in free radicals scavenging accounts for its antioxidant property. It is used in cosmetic product and as a coagulant in tofu processing. (NCI05)

Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging

InactiveUS6384079B1Deepening of skin linesSkin lossBiocideCosmetic preparations3-Hydroxypropionic acidPropanoic acid
Uses of topical compositions comprising a 2-hydroxycarboxylic acid or related compound to alleviate or improve signs of skin, nail and hair changes associated with intrinsic or extrinsic aging are disclosed. 2-Hydroxycarboxylic acids and their related compounds include, for example, 2-hydroxyethanoic acid, hydroxypropanoic acid, 2-methyl 2-hydroxypropanoic acid, 2-phenyl 2-hydroxyethanoic acid, 2-phenyl 2-methyl 2-hydroxyethanoic acid, 2-phenyl 3-hydroxypropanoic acid, 2,2-diphenyl 2-hydroxyethanoic acid, 2-hydroxybutane-1,4-dioic acid, 2,3-hihydroxybutane-1,4-dioic acid, 2-carboxy 2-hydroxypentane-1,5-dioic acid, 2-ketopropanoic acid, methyl 2-ketopropanoate, ethyl 2-ketopropanoate, and gluconolactone. Topical application of compositions comprising 2-hydroxycarboxylic acid and / or related compounds has been found to alleviate or improve skin lines; blotches; blemishes; nodules; wrinkles; pigmented spots; atrophy; precancerous lesions; elastotic changes characterized by leathery, coarse, rough, dry and yellowish skin; and other skin changes associated with intrinsic aging or skin damages caused by extrinsic factors such as sunlight, radiations, air pollution, wind, cold, dampness, heat, chemicals, smoke and cigarette smoking. Topical applications of such compositions have also been found to improve the overall qualities of nail and hair affected by intrinsic aging or damaged by extrinsic factors.
Owner:TRISTRATA TECH

Method for preparing composite hydrogel of sodium alginate and artemisia desertorum seed gum

The invention discloses a method for preparing a composite hydrogel of sodium alginate and artemisia desertorum seed gum. The method comprises the steps of: introducing the artemisia desertorum seed gum in a sodium alginate solution system, and slowly releasing Ca<2+> in a glucolactone solution by utilizing micropore calcium carbonate, thereby forming the composite hydrogel of sodium alginate and artemisia desertorum seed gum in situ. The properties of the sodium alginate and the artemisia desertorum seed gum are complementary, so that the water absorption capability and the mechanical properties of the sodium alginate base composite hydrogel are enhanced and the application range of the sodium alginate serving as a medicament carrier and a tissue engineering material is expanded. The strength and the gelation time of the the composite hydrogel prepared by the method can be regulated and optimized by changing the proportion of each component and the concentration of glucolactone so as to meet the requirements in different fields. In addition, the method is simple without needing special equipment; the reaction occurs in normal temperature and normal pressure and is simple and controllable; and the method is low in cost and suitable to popularization and application.
Owner:NORTHWEST NORMAL UNIVERSITY

Polylactic-co-glycolic acid (PLGA)/calcium carbonate compound microsphere with porous shell and preparation method for compound microsphere

The invention discloses a polylactic-co-glycolic acid (PLGA)/calcium carbonate compound microsphere with a porous shell and a preparation method for the compound microsphere. The preparation method comprises the following steps of: a, dissolving PLGA in a methylene dichloride organic solvent to obtain a PLGA oil phase; adding calcium carbonate powder to the PLGA oil phase; stirring and performing ultrasonic treatment to obtain organic/inorganic uniform mixed liquid; b, dissolving glucolactone in polyvinyl alcohol (PVA) aqueous solution to obtain acid PVA aqueous solution; c, dispersing the mixed liquid obtained in the step a into the acid PVA aqueous solution obtained in the step b under the condition of stirring to obtain oil-in-water single emulsion; d, continue stirring under the condition of reduced pressure to enable methylene dichloride in an oil phase drop to volatilize to obtain solidified compound microspheres; and e, collecting the microspheres in the step d; washing by using deionized water; and performing freeze drying. A pore-forming agent is not introduced by the method disclosed by the invention, thus, a porous structure exists on the surface of the prepared compound microsphere, and the compound microsphere is in favor of cell growth.
Owner:SOUTH CHINA UNIV OF TECH

Organ preservation solution and method for preparing same

ActiveCN102726366AAvoid damageDisadvantages of Avoiding PrecipitationDead animal preservationPhosphateArginine
The invention relates to an organ preservation solution and a method for preparing the same. The method comprises the following steps of: (1) adopting double buffer pairs of citric acids and phosphates to enable the PH value of a solution to be maintained in a range of 7.5 to 8; (2) adding active ingredients such as adenosine, L-arginine, tryptophan, ligustrazine hydrochloride, reduced glutathione and the like and keep the solution stable; (3) to maintain a hypertonic property of the preservation solution with an osmotic pressure of 350-380 mOsm/L, adopting trehalose and gluconolactone as impermeable substances to effectively prevent cellular edema; and (4) adopting polyethylene glycol with a large molecular weight as a colloidal substance to effectively prevent extracellular space from expanding. Compared with the prior art, the method employs raw materials which are all homemade medicinal components and meet the standards of national pharmacopoeia, and are cheap and free of incompatibility; the organ preservation solution prepared is a colorless and transparent liquid which has stable properties, and can be sterilized by high temperature and high pressure, stored at normal temperature or low temperature, and refrigerated, and thus preparation, transportation, storage and usage of the organ preservation liquid are all very easy and convenient.
Owner:SHANGHAI GENEXT MEDICAL TECH
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