The invention relates to cosmetic and dermocosmetic compositions comprising
stem cell-derived
callus extracts from
Punica granatum obtained via standardized
in vitro plant stem cell cultures. The extracts are rich in polyphenols, flavonoids,
ellagic acid, anthocyanins, tannins, vitamins C, E, and K, and amino acids, providing potent
antioxidant, anti-inflammatory, regenerative, moisturizing, and brightening effects. These compositions stimulate collagen synthesis, enhance
skin elasticity and firmness, protect against
oxidative stress, reduce redness and
irritation, and promote overall
skin renewal. Formulations include aqueous-based ampoules, essences, or serums containing 0.5-5% by weight of the extract, optionally combined with humectants,
skin-soothing agents, antioxidants, and stabilizers. The invention further discloses optimized methods for
callus induction, extraction, and formulation, ensuring reproducibility, high bioactive yield, stability,
scalability, and
sustainable production. This provides a scientifically validated, eco-friendly cosmetic solution delivering comprehensive skin benefits, addressing anti-aging, regeneration, hydration, and brightening needs.