208 results about "Ellagic acid" patented technology

Aiming at the inadequacy of existing hemostatic materials for large-scale trauma and serious bleeding, the present invention provides a silk fibroin complex loaded with a polyhydroxy phenolic compound and a preparation method therefor. The complex is prepared by self-assembly of the polyhydroxy phenolic compound and the silk fibroin. The silk fibroin is subjected to a β-sheet conformation transformation process. The polyhydroxy phenolic compound is preferably an indissoluble compound, most preferably ellagic acid. The feeding ratio of the polyhydroxy phenolic compound to the silk fibroin is a mass ratio of ˂ 1:1, preferably 1:2 to 1:16, more preferably 1:4. The hemostatic ability of the complex is significantly superior to that of the polyhydroxy phenolic compound, the silk fibroin, Yunnan Baiyao, tranexamic acid, chitosan hemostatic powder, and the like. Meanwhile, the complex has a larger particle size and mass than the silk fibroin, and can rapidly settle to a bleeding site in blood. The complex exhibits no cytotoxicity, is blood-insoluble, and is capable of self-degradation in vivo, demonstrating high safety. Meanwhile, the complex has the characteristics of wound healing, antibiosis, infection resistance, adhesion resistance, and the like, and can be applied to the preparation of corresponding formulations.

The invention discloses a zirconium-based MOF material and a preparation method and application thereof, in the zirconium-based MOF material, metal ions are Zr < 4 + >, an organic ligand is ellagic acid, a conditioning agent is gallic acid, and the material has an oxygen vacancy structure and a hierarchical pore structure; the preparation method comprises the following steps: (1) mixing ellagic acid, gallic acid, zirconium oxychloride octahydrate and a solvent, and carrying out solvothermal reaction; and (2) washing and drying the solid after the reaction in the step (1) to obtain the zirconium-based MOF material. According to the invention, renewable and low-cost ellagic acid and gallic acid are respectively used as an organic ligand and a conditioning agent, and an oxygen vacancy structure is constructed in a competitive coordination manner, so that more hydroxyl and unsaturated metal Zr active sites are exposed, the interaction with formaldehyde (HCHO) is enhanced, and meanwhile, the oxygen vacancy structure can be used as an oxygen vacancy catalyst. And the existence of the hierarchical pore structure can effectively promote mass transfer, so that the HCHO adsorption capacity is improved.

The invention discloses a COF electrostatic spinning wound dressing with near-infrared response and antioxidant activity and a preparation method of the COF electrostatic spinning wound dressing, and belongs to the field of application materials and technologies. The COFs are synthesized from cobalt hexafluorophthalocyanine (CoPcF16) and ellagic acid (EA). The COFs is prepared into the spinning membrane, and the COFs spinning membrane has very strong oxidation resistance, can effectively remove excessive endogenous ROS, can respond to near infrared to generate exogenous ROS, and can effectively kill bacteria at a wound and improve blood flow and healing of the wound. The COFs spinning membrane prepared by the invention is simple and convenient in preparation method, good in biocompatibility, strong in oxidation resistance and capable of responding to near infrared to produce ROS, and has strong application potential in the field of treatment of a series of infected wounds, especially treatment of diabetic foot ulcers.

The invention discloses a method for improving in-vivo and in-vitro antioxidant activity of pomegranate peel polyphenol extract through combined enzymolysis of tannase and beta-glucosidase, and relates to the technical field of food science and biology. The pomegranate peel polyphenol extract provided by the invention is obtained from pomegranate peel powder through solvent extraction. According to the present invention, tannase and beta-glucosidase are adopted to perform single or combined enzymolysis on the pomegranate peel polyphenol extract, and the determination on the in vitro antioxidant activity of the pomegranate peel polyphenol extract shows that the antioxidant activities of DPPH and ABTS after the combined enzymolysis are improved by 29.84% and 29.30% compared with the antioxidant activities of the untreated polyphenol extract; the UPLC-ESI-QTOF-MS is used for identifying and analyzing the components of the enzymatic hydrolysate, the content of macromolecular ellagic tannin is obviously reduced, and the content of micromolecular ellagic acid and gallic acid is increased. The enzymolysis polyphenol is applied to D-galactose induced oxidative stress mice, and the result shows that the oxidative damage relieving effect of the enzymolysis polyphenol on the mice is better than that of untreated polyphenol.

The invention provides a silk fibroin hemostatic sponge loaded with polyhydroxy phenolic compounds and a preparation method of the silk fibroin hemostatic sponge, aiming at the defect that hemostatic materials have poor effects on large wounds and serious bleeding, and the silk fibroin hemostatic sponge loaded with the polyhydroxy phenolic compounds is prepared from silk fibroin compounds loaded with the polyhydroxy phenolic compounds, wherein the silk fibroin compound loaded with the polyhydroxy phenolic compound is prepared from the polyhydroxy phenolic compound and silk fibroin according to the feeding mass ratio of 1t; the material is prepared in a 1: 1 self-assembly mode. The polyhydroxy phenolic compound is preferably insoluble and most preferably ellagic acid, and the feeding ratio of the polyhydroxy phenolic compound to the silk fibroin is preferably 1: 2-1: 16 and more preferably 1: 4. The hemostatic capacity of the silk fibroin compound loaded with the polyhydroxy phenolic compound is remarkably superior to that of silk fibroin, Yunnan Baiyao, tranexamic acid, chitosan hemostatic powder and the like, and the silk fibroin compound is free of cytotoxicity, free of hemolysis, capable of being self-degraded and high in safety. The silk fibroin hemostatic sponge loaded with the polyhydroxy phenolic compound has excellent hemostatic performance, is easy to peel, does not cause secondary damage, and can be self-degraded.

The invention discloses a whitening and freckle-removing essence which comprises the following components: a calendula extract, pure water, 1, 2-pentanediol, methylpropanediol, carbomer, arginine, nicotinamide, a freckle-removing essence, a natural plant penetration enhancer, hydroxyethyl piperazine ethanesulfonic acid, small-molecule ellagic acid, dipropylene glycol, 1, 2-propylene glycol, ethanol and water. The composition is prepared from 1, 2-hexanediol, caprylyl glycol, ethylhexylglycerin, raspberry ketone glucoside and a PEG / PPG-17 / 6 copolymer. The invention further discloses a production process of the whitening and freckle-removing essence water. The invention has the following advantages: with pure natural plants as a main product, the skin has obvious change after being used for a week, specifically, pregnancy spots, sunburn, chloasma, pigmentation after inflammation and other color spots on the face can be reduced and faded, the face skin can be whitened, the face is mild and non-irritating, and the effects of improving uneven skin color, brightening skin color and the like can be achieved.

The present invention provides an anti-aging, whitening, freckle-removing, moisturizing skin care water and a preparation process thereof. A preparation process for an anti-aging, whitening, freckle-removing, moisturizing skin care water comprises the following steps: supercritical CO2 extraction of oat-yarrow extract; ultrasonic-enzymatic hydrolysis-assisted reflux extraction and concentration; adding oxidized resveratrol, salidroside and ellagic acid; adding purified water to dissolve and adding sodium alginate and glycerol; adding p-anisic acid and aromatic alcohol and homogenizing and mixing. The present invention is a skin care water prepared by first extracting extracts of bletilla striata, wormwood leaf, peony bark, oat and yarrow, and then adding oxidized resveratrol, salidroside, ellagic acid, sodium alginate, glycerol, p-anisic acid and aromatic alcohol. The skin care water not only has the effects of anti-aging, whitening, freckle removal and moisturizing, but also because its raw materials are all natural plant ingredients and no chemical agents are added, therefore, it will not irritate the skin and has no side effects, and can be used for a long time.

The invention relates to the technical field of materials, in particular to a fiber-reinforced starch-based fireproof and moisture-proof composite material and a preparation process thereof. Comprising the following steps: toughening and fireproof modification of lignin fibers; carrying out site selection phosphorylation on the starch; and carrying out in-situ bonding of phenylboronic acid and hydrophobic modification of the blended material. The preparation method comprises the following steps: preparing a pre-assembled solution from ellagic acid, tannic acid and tetrabutylammonium bromide, then adding ZrOCl2 powder in batches to form a continuous ceramic phase ZrO6, forming an interlocking structure with a carbon layer to enhance the flame retardant property, then adding lignin fibers in the last batch, adjusting the pH value, and condensing to generate Zr-O-C covalent bonds, so as to obtain the composite material. The prepared modified lignin fiber is subsequently blended with site-selected phosphorylated starch, so that the mechanical property of the modified lignin fiber is enhanced, and heat and mass transfer between a gas phase and a condensed phase can be hindered when the temperature is too high, thereby greatly improving the flame retardant property of the composite material.

The invention belongs to the technical field of sewage treatment and new materials, and discloses an iron-based metal-organic complex catalyst, a preparation method and a method for removing ofloxacin in a water body, and the catalyst is prepared by taking ellagic acid EA with an electron-rich structure as a ligand and iron atoms as coordination metal through a hydrothermal method. The invention relates to an iron-based metal-organic complex FeMOCs material which is an iron-based metal-organic complex FeMOCs material and is used for preparing six-coordination black powder with an amorphous nano-scale sheet structure and micron-scale cluster aggregation, the surface pore size distribution is mainly mesopores, and an efficient catalytic interface and a sufficient microscopic space are provided for a rapid and powerful reaction of an oxidizing agent persulfate and ofloxacin in a water body. The catalyst has an adsorption-degradation synergistic effect, and is named as an EFE-150 catalyst. The catalyst is synthesized by adopting a solvothermal method, is applied to catalyzing PDS to efficiently remove ofloxacin in a water body, has the characteristics of quick response, self-sustaining, low cost and the like, and can meet the requirements of large-scale popularization and application.

The invention discloses an EGFR (epidermal growth factor receptor) targeted nano-drug carrier and a preparation method thereof, the EGFR targeted nano-drug carrier comprises drug-loading nanoparticles, an erythrocyte membrane coating the drug-loading nanoparticles and GE11 peptide connected to the erythrocyte membrane, and the drug-loading nanoparticles are formed by connecting tannic acid, ellagic acid and 1, 4-phenyldiboronic acid through boric acid ester bonds. The EGFR targeted nano-drug carrier disclosed by the invention can be enriched at an EGFR overexpressed tumor site in a targeted manner, and can be effectively prevented from being cleared by an immune system, and the drug loaded by the drug-loaded nanoparticles is released in a high-active oxygen environment, so that the treatment effect on tumors can be improved, and the toxic and side effects on normal tissues can be reduced; and photothermal therapy and chemotherapy effects can be simultaneously generated under NIR illumination, and the anticancer efficiency can be remarkably improved through the synergistic effect of the photothermal therapy and the chemotherapy.

The invention discloses an organic fertilizer suitable for tea yield increase and insect killing and a preparation method thereof, and relates to the technical field of organic fertilizer and microbial fertilizer manufacturing. The organic fertilizer is prepared from straw, chicken manure, radix inulae, clinacanthus nutans, affine cudweed, periploca forrestii schltr, ellagic acid-rice protein zymolyte, sodium laurate modified diatomite, sodium humate, urea, compound microorganism bacteria and water. The compound microorganism bacterium is composed of candida utilis saccharomycetes and neurospora intermedia. The compound microorganism bacteria in the organic fertilizer are beneficial to accelerating fermentation decomposition of the straw, the chicken manure, the sodium humate, the urea and the traditional Chinese medicine plants and promoting macromolecular substances to be converted into micromolecular active ingredients, then ellagic acid-rice protein zymolyte and sodium laurate modified diatomite are supplemented, and the yield of tea tree planting is increased through reasonable proportion of nutritional ingredients.

The invention belongs to the technical field of biology, and particularly discloses an exosome preserving fluid, which is prepared from the following ingredients in parts by weight: 0.01 to 0.1 part of sodium hyaluronate, 0.1 to 1 part of threonine, 0.5 to 1.2 parts of chitosan, 1 to 4 parts of bovine serum albumin, 1.5 to 3.5 parts of phospholipid substances, 3 to 9 parts of polyhydroxy compounds, 2 to 10 parts of ellagic acid, 2 to 10 parts of tomato extracts, 5 to 15 parts of dimethyl sulfoxide and 64.1 to 66.99 parts of normal saline. The exosome preserving fluid provided by the invention can provide stable conditions for storing the exosome, so as to protect the structure of the exosome and biological information molecules or drugs carried by the exosome from biological, chemical or mechanical damage, effectively maintain the stability, activity and function of the exosome, and ensure that the exosome is not lost in the preservation process.

The invention relates to the technical field of fermentation, in particular to fermented lonicera caerulea juice capable of reducing astringency and increasing the content of organic calcium as well as a preparation method and application of the fermented lonicera caerulea juice. The fermented lonicera caerulea juice disclosed by the invention is prepared from the following components in parts by mass: 95 to 105 parts of lonicera caerulea pulp, 0.5 to 1 part of eggshell powder and 1 to 4 parts of fermentation bacteria. The calcium content in the fermented lonicera caerulea juice prepared by the method disclosed by the invention can be up to 2000mg / L, bitter and astringent substances such as ellagic acid and secologanin are effectively reduced, the bitter and astringent taste is improved, and the roundness and aroma acceptance of the whole taste are improved. The obtained lonicera caerulea fermented juice is pleasant in flavor, balanced in nutrition, high in calcium content and suitable for development of functional beverages and healthy food.

The invention belongs to the technical field of cigarette filtration, and relates to a preparation method and application of a biomass-based supramolecular assembly functional material. According to the method, a large number of plant-based fibers existing in the nature serve as a substrate material, gallic acid and ellagic acid with small molecular sizes are adopted to be matched with tannic acid with large molecular sizes to be coordinated with metal ions, tannic acid molecules can be separated, crowding of the tannic acid molecules is relieved, the utilization rate of hydroxyl on the tannic acid molecules is increased, and the yield of the tannic acid is increased. The molecular assembly efficiency is improved. A metal-polyphenol network functional film is generated on the surface of the plant-based fiber material based on the polyphenol regulated supramolecular assembly structure, and the prepared material can effectively remove tar substances, especially polycyclic aromatic hydrocarbon strong cancerogenic substances, in cigarette smoke, so that harmful ingredients inhaled by smokers are reduced, meanwhile, the smoking experience feeling is not affected, and the cigarette quality is improved. The palatability of the filter tip is improved, and the filter tip has better application value and market prospect in the technical field of cigarette filtration.

The invention discloses a dysphagia pill fingerprint spectrum establishment method and an established fingerprint spectrum, belongs to the technical field of analysis and detection of traditional Chinese medicine preparations, and provides a dysphagia pill fingerprint spectrum establishment method which comprises the following steps: mixing a dysphagia pill test sample with petroleum ether, performing Soxhlet extraction, mixing medicine residues with a methanol aqueous solution, performing heating reflux, performing column chromatography, and performing freeze drying to obtain a dysphagia pill fingerprint spectrum. Taking filtrate to obtain a test solution; mixing ellagic acid, liquiritin, ammonium glycyrrhizinate and sesamin reference substances with methanol to obtain a mixed reference substance solution; sucking the test solution and the reference solution, injecting into a liquid chromatograph, and collecting a chromatogram; introducing the chromatogram of the test sample into a traditional Chinese medicine chromatographic fingerprint spectrum similarity evaluation system, selecting common chromatographic peaks as common peaks, generating a dysphagia pill contrast fingerprint spectrum, and calculating the relative retention time and the relative peak area of each common peak to obtain the HPLC fingerprint spectrum of the dysphagia pill. The quality of the dysphagia pill can be comprehensively evaluated by using the map, and the quality stability, consistency and controllability of the dysphagia pill are ensured.

The invention relates to the technical field of component detection, in particular to a method for determining five components in quisqualis family medicinal materials based on quantitative analysis of multi-components by single marker. According to the method for simultaneously and quantitatively detecting the five components in the medicinal materials of the Quisqualis family based on the quantitative analysis of multi-components by single marker, the contents of index components of the five components are simultaneously determined by the quantitative analysis of multi-components by single marker, and the content of chebulaic acid, 1, 2, 3, 4-tetramethyl-3, 5-dichlorphenoxyacetic acid and 1, 2, 3, 4-tetramethyl-3, 5-dichlorphenoxyacetic acid can be calculated through relative correction factors only by using one reference substance of chebulaic acid as an internal reference substance. According to the method, the specific content of the galloylglucose, the 1, 2, 3, 4, 6-O-tetragalloylglucose, the 1, 2, 3, 4, 6-O-pentagalloylglucose and the ellagic acid can be measured, and the method has the advantages of being easy to operate, high in sensitivity, accurate in measurement and high in applicability.

The invention relates to a preparation method of a nano waterproof fabric. According to the method, ellagic acid is introduced in the self-polymerization process of dopamine for in-situ reduction, a polydopamine bonding layer and a silver nanoparticle anchoring layer are synchronously constructed on the surface of nano silicon dioxide, and then perfluorodecyltriethoxysilane is catalyzed by silver nanoparticles for a regioselective click chemical reaction, so that the nano silicon dioxide is obtained. The multifunctional bionic core-shell particles with catalytic activity and super-hydrophobicity are prepared. The particles are compounded with a fluorosilicone copolymer containing dynamic disulfide bonds, a fluorosilicone polymer containing boric acid ester groups and a tannic acid-metal complex to form a double-dynamic cross-linking finishing agent system. After a fabric is subjected to ultraviolet / ozone pretreatment, discontinuous polydopamine nanodot arrays are formed on the surfaces of fibers through short-time dopamine polymerization to serve as catalytic sites, then interface priority crosslinking is triggered by utilizing the sites, and finally, dynamic keys are driven to cooperatively exchange through ultraviolet light fixation and heat treatment, so that the intelligent dynamic waterproof membrane is formed.

The invention belongs to the technical field of cosmetics, and provides a synergistic whitening composition, application thereof and cosmetics, the synergistic whitening composition comprises ellagic acid and tetrahydromagnolol, and the mass ratio of the ellagic acid to the tetrahydromagnolol is 50: 1-1: 10. In the composition provided by the invention, the ellagic acid and the tetrahydromagnolol have a synergistic whitening effect, and in the aspect of inhibiting melanogenesis, the effect of the composition is obviously greater than the sum of the effects of independently using the ellagic acid and independently using the tetrahydromagnolol.

The invention relates to the technical field of traditional Chinese medicines, in particular to a processing method and a quality control method for toxicity reduction and efficacy enhancement of radix cynanchi bungei. According to the method, the content of alangiine, the content of ellagic acid, the common peak area of characteristic peaks and the content of water-soluble extracts in the wine-roasted berberis scenting decoction pieces are measured by adopting a high performance liquid chromatography (HPLC) method, and subjective assignment is carried out on the characters of the wine-roasted berberis scenting decoction pieces by combining Delphi evaluation to serve as evaluation indexes; the method comprises the following steps: determining the weight coefficient of each index by adopting an analytic hierarchy process-index repeatability correlation mixed weighting method (AHP-CRITIC), and screening the optimal wine roasting process of the Zhuang medicine Tibetan scene by combining the three factors of the frying temperature, the frying time and the yellow wine amount with star point design (CCD)-effect surface (RSM) according to the coefficients. And finally determining the optimal process of stir-frying the radix berberidis with wine as follows: the stir-frying temperature is 150 DEG C, the stir-frying time is 16min, the amount of yellow rice wine is 10%, and moistening is performed for 24h.

The invention discloses an ellagic acid-copper metal organic framework nano material, a preparation method thereof and application of the nano material as an anti-tumor drug carrier. According to the nano material, natural polyphenol ellagic acid is used as an organic ligand, copper ions are used as a metal center, and a three-dimensional supramolecular frame structure is formed through coordination. The preparation method comprises the following steps: mixing an N-methyl pyrrolidone solution of ellagic acid with a methanol solution of copper sulfate, and stirring and reacting at room temperature to efficiently synthesize the copper sulfate. The nano material has excellent antibacterial activity and efficient anti-tumor drug loading capacity, has the intelligent drug release characteristic of dual response of pH and glutathione, and can accurately release drugs in a tumor microenvironment. The nano material provided by the invention can be used as an anti-tumor drug carrier, synchronously realizes anti-tumor and antibacterial dual effects, effectively prevents and treats bacterial infection complications in tumor treatment, and provides a new material for developing a new strategy for tumor synergistic treatment.

The invention discloses a polyellagic acid nanofiber as well as preparation and application thereof. The invention relates to a preparation method of polyellagic acid nanofibers, which comprises the following step: by taking ellagic acid as a raw material, an alkaline aqueous solution as a solvent and sodium periodate as an oxidizing agent, reacting to prepare the polyellagic acid nanofibers. The method is simple and easy to implement, and the prepared polyellagic acid is in a nanofiber shape, good in water solubility, large in specific surface area and higher in free radical scavenging capacity.

This application relates to the technical field of flame retardant preparation, in particular to a synthesis method of a bio-based phosphorus-nitrogen synergistic flame retardant and a highly flame-retardant polymer composition prepared by using the same. Synthesis method of the bio-based phosphorus-nitrogen synergistic flame retardant: After stirring ellagic acid, an acid-binding agent, and an organic solvent evenly, add diaminophosphoryl chloride at room temperature, continue to react at room temperature for 3 to 4 hours, and finally filter and drain the solvent to obtain the bio-based phosphorus-nitrogen synergistic flame retardant. The flame retardant in this application contains a super-large conjugated structure and has high thermal stability. Introducing phosphorus and nitrogen elements into its structure as a bio-based phosphorus-nitrogen synergistic flame retardant not only meets the requirements of green chemistry and sustainable development, promotes green and low-carbon development, but also can exert the flame retardant synergistic effect of phosphorus and nitrogen, enabling the polymer material to promote the formation of a carbonized layer during combustion, isolate oxygen and energy transfer, reduce the concentration of combustible gases and the release of toxic flue gas, and improve the flame retardant performance of the material.

The invention provides a novel application of a raspberry extract. It is found through tests that any one of isoquercitrin, ellagic acid, vanillic acid, oleanolic acid, kaempferol-3-O-rutinoside, kaempferol-3-O-sophoroside, tiliroside, tormentic acid and raspberry extract can remarkably improve the activity of the human ovarian granular cells or remarkably improve the oxidative stress level, and the activity of the human ovarian granular cells can be remarkably improved. According to the present invention, the ovarian function can be effectively protected by the eight components, the ovarian function can be effectively protected by the eight components, or the mitochondrial membrane potential level can be significantly regulated and controlled, or the estrogen level in the microenvironment can be effectively maintained, such that the ovarian function can be effectively protected by the eight components, and the raspberry extract containing the eight components. The invention provides a new choice for ovarian function protection products, and also provides a new application for the substances.

The invention relates to the technical field of cosmetics, and discloses a herbal probiotic composition with whitening and anti-aging effects and a preparation method thereof. The herbal probiotic composition is prepared from alpha-arbutin, licoflavone, bakuchiol, resveratrol, ellagic acid, a metagen complex, skin micro-ecological prebiotics, sodium phytate, ferulic acid, rosemary polyphenol, polycystic liposome and the balance of a carrier suitable for skin. The herbal probiotic composition disclosed by the invention realizes stable co-delivery of hydrophilic and lipophilic activities and effective retention of cuticles under mild pH, synergistically inhibits blackness, resists oxidation and supports microecology, and improves the effective content and batch-to-batch consistency in the shelf life through metal ion accessibility control, so that the whitening and anti-aging effects are improved.

The present invention provides a method for identifying HPLC characteristic spectra of bergenia medicinal materials, decoction pieces, extracts and their formula particles, comprising the following steps: A) dissolving a test sample with a solvent, extracting, and obtaining a test solution; B) determining the test solution with high performance liquid chromatography to obtain HPLC characteristic spectra of bergenia medicinal materials, decoction pieces, extracts and their formula particles; the chromatographic conditions of the high performance liquid chromatography are: the chromatographic column is a C18 column; the mobile phase A is methanol, and the mobile phase B is a 0.1% phosphoric acid solution, and the gradient elution. The present invention adopts high performance liquid chromatography, selects methanol-0.1% phosphoric acid solution as the mobile phase for gradient elution, and uses arbutin, gallic acid, catechin, bergenin, and ellagic acid as reference substances to establish HPLC characteristic spectra of bergenia medicinal materials, decoction pieces, extracts and their formula particles, with good repeatability and precision, stable and reliable methods, and can control the quality of bergenia medicinal materials, decoction pieces, extracts and their formula particles.

The present invention provides an oral composition that can be used for anti-obesity, suppressing fat absorption, suppressing an increase in neutral fat, suppressing sugar absorption, suppressing an increase in blood sugar level, reducing body fat, or reducing BMI. An oral composition containing gallic acid and catechins, The oral composition has a mass ratio of gallic acid:catechins=1:0.1 to 5. The oral composition preferably further contains ellagic acid. It is also preferably used for anti-obesity, suppression of fat absorption, suppression of increase in neutral fat, suppression of sugar absorption, suppression of increase in blood glucose level, reduction of body fat, or reduction of BMI.

An object of the present disclosure is to provide a novel method for producing an ellagic acid-containing composition, the method capable of improving the solubility of ellagic acid. The present embodiment is a method for producing an ellagic acid-containing composition, including: a step of providing a solution containing at least an aqueous medium and a raw material derived from a plant of the genus Terminalia, containing ellagic acid; and a step of heat-treating the solution. The present embodiment is the production method, further including a step of a hydrolysis treatment to hydrolyze ellagitannin contained in the raw material to produce additional ellagic acid, wherein the hydrolysis-treated solution is heat-treated.

The invention discloses application of ellagic acid in preparation of a medicine or a biological product for preventing or relieving ultraviolet radiation damage and aging, and belongs to the technical field of biological medicine and radiation protection. Experimental verification shows that ellagic acid with effective concentration can promote expression of antioxidant related genes, reduce expression of inflammation response genes and expression of apoptosis related genes, eliminate active oxygen and inhibit lipid peroxidation reaction, so that oxidative damage, inflammatory reaction and apoptosis caused by ultraviolet radiation are effectively relieved, and the anti-inflammatory effect of ellagic acid is improved. The stress tolerance of an organism is improved, and the aging health risk induced by ultraviolet radiation is relieved; the medicine or biological product can be applied before and / or after exposure of ultraviolet radiation, and is suitable for preventing or relieving oxidative damage and cell aging caused by ultraviolet radiation. The invention provides a new way for developing safe and effective ultraviolet radiation protection and anti-aging preparations.

The invention relates to low-sugar gum soft sweets and a preparation method thereof. The soft sweets comprise the following raw materials in parts by weight: 18-35% of a pectin compound, 40-50% of a sweetening agent, 3-5% of a plasticizer, 0.3-0.8% of malic acid, 0.2-0.5% of sodium citrate and the balance of deionized water. Wherein the pectin compound comprises the following raw materials in percentage by weight: 10-20% of a cation matrix, 15-25% of an anion matrix, 5-10% of a neutral matrix and the balance of deionized water; the cation matrix comprises chitosan hydrochloride and calcium salt, the anion matrix comprises the following raw materials: low-methoxyl pectin, high-methoxyl pectin, ellagic acid and cumaric acid, and the neutral matrix is locust bean gum. The cation matrix, the anion matrix and the neutral matrix of the pectin compound cooperate to make up the defects of weak structure, poor water retention, easy aging and the like caused by sucrose deficiency in a low-sugar environment, so that the soft sweets have both elasticity and toughness.

The invention relates to a novel beverage and a preparation method thereof. Comprising the following components in percentage by weight: 0.05%-0.6% of a double-petal red rose distillation extracting solution, 0.05%-0.6% of food-grade hyaluronic acid, 0.05%-0.6% of xylitol or erythritol, 0.1%-0.3% of a butterfly bean flower extracting solution, 0.05%-0.2% of a turmeric root extracting solution, 0.03%-0.1% of mint leaf essence, 0.1%-0.4% of chia seed powder, 0.2%-0.5% of aloe juice, 0.1%-0.3% of a pomegranate extracting solution, 0.05%-0.2% of a green tea extracting solution, 0.02%-0.1% of citric acid and the balance of water. Hyaluronic acid and rose hydrolat are added, so that the oral liquid has the effects of moisturizing, resisting aging, soothing liver-qi stagnation and relieving and reducing pressure after being orally taken, aloe polysaccharide and chia seeds form a stable colloidal network, satiety and skin repair capacity are improved, low sugar and low burden are achieved, pomegranate ellagic acid has the effects of resisting inflammation, natural color matching with butterfly bean flowers is achieved, visual interest is enhanced, green tea catechin and curcumin are compounded to resist oxidation, promote metabolism and strengthen immunity, and the oral liquid has the effects of promoting metabolism and improving immunity. And the defects of irritation, single nutrition and the like of the traditional beverage are overcome.