48 results about "Dual response" patented technology

The invention belongs to the technical field of fluorescence detection, and provides a dual-emission carbon dot, a visual hydrogel sensing platform prepared from the dual-emission carbon dot and application of the dual-emission carbon dot in order to solve the problem that field real-time detection cannot be realized in current tetracycline detection. The dual-emission fluorescent carbon dots DE-CDs are synthesized by dissolving toluene diisocynate, fennel and m-phenylenediamine (m-PD) in ultrapure water to serve as precursors, and reacting for 6 hours by controlling the reaction temperature to be 220 DEG C through a one-pot hydrothermal method. Two emission wavelengths (432 nm and 515 nm) are shown under different excitation wavelengths. A fluorescence sensor with double response signals is constructed and used for detecting tetracycline. The sensor shows a very strong index relationship in the range of tetracycline of 0-118 [mu] M, and the detection limit is 53.4 nM. A fluorescent hydrogel detection platform integrated with a smart phone is established, and rapid, portable and on-site detection of tetracycline in a water sample is successfully realized. And an effective strategy is provided for combination of laboratory precision testing and on-site rapid testing.

The invention is suitable for the technical field of electrochemical energy storage, and provides an integrated structure solid-state battery module constructed based on SiO2 aerogel powder and a preparation method of the integrated structure solid-state battery module. And a stress buffering-ion conduction-thermal triggering self-repairing collaborative interface system is constructed. According to the Janus powder, a ZrO2 nanocluster and a SiO2 network form a rigid core, a dynamic shell containing a Diels-Alder dynamic covalent bond is grafted on the outer surface and the inner wall of a pore channel, and a lithium salt-ionic liquid compound is loaded in pores; a vertical columnar stress supporting framework is formed through a transient liquid phase auxiliary cold sintering process, and two-step thermal triggering self-repairing treatment is combined, so that stress buffering of electrode volume change in the charging and discharging process and interface self-repairing in the early stage of thermal abuse are achieved. The interface stability, the cycle life and the thermal safety of the solid-state battery are remarkably improved, and the solid-state battery is suitable for power batteries, high-capacity energy storage batteries and other scenes.

The invention discloses zwitterionic concrete internal curing hydrogel based on humidity-pH dual responsiveness and a preparation method of the zwitterionic concrete internal curing hydrogel, and belongs to the technical field of building materials. The water-based cleaning agent is prepared from the following raw material components in percentage by weight: 6%-8% of N-vinyl imidazole, 8%-12% of 2-methylimidazole, 6%-8% of 2-acrylamido-2-methylpropanesulfonic acid, 2%-4% of sodium p-styrenesulfonate, 26%-30% of acrylic acid, 18%-21% of N-vinyl pyrrolidone, 15%-18% of glycidyl methacrylate, 2%-5% of nano montmorillonite powder, 0.05%-0.1% of divinyl benzene, 0.05%-0.15% of N, N-dimethylformamide and the balance of water. The invention discloses an anti-freezing agent which is prepared from the following components in percentage by weight: 0.1%-0.3% of N, N-methylene bisacrylamide, 0.1%-0.3% of 1-[4-(2-hydroxyethoxy)-phenyl]-2-hydroxy-2-methyl-1-propane-1-ketone, 0.5%-0.8% of ammonium persulfate and 0.5%-0.8% of sodium hydrogen sulfite. Double response to the internal humidity and pH value of the concrete can be achieved, and the requirement for precise internal curing of modern high-performance concrete is met.

The application discloses a low-oxygen and pH dual-response nano-carrier, a drug-loaded nanoparticle and application thereof, and belongs to the technical field of biological medicines. The nano-carrier with moderate particle size and low-oxygen and pH dual-response is obtained by using the reaction of aldehyde benzoic acid, nonaethylene glycol and azo-p-phenetidine, the nano-carrier is specifically targeted to a tumor site, and then specifically releases drugs, thereby reducing toxic side effects; meanwhile, after the nano-carrier responds, benzaldehyde groups are released, the benzaldehyde groups are covalently connected with proteins on a lysosome membrane, the structure and activity of the proteins are changed, the lysosome membrane is broken after the proteins are denatured, the permeability of the lysosome membrane is increased, the nano-carrier cannot be discharged to the extracellular, the drug concentration in cells is greatly improved, and the drug bioavailability of the nano-carrier is significantly improved; in addition, the drug loading capacity of the nano-carrier is high, and therefore, the nano-carrier has a good application prospect.

The invention provides a method for preparing a large-area side-chain cholesteric liquid crystal elastomer thin film based on a blade coating method and application of the large-area side-chain cholesteric liquid crystal elastomer thin film. By controlling the content of sulfydryl functional groups in a system and accurately controlling key process parameters such as the blade coating rate and the blade coating temperature in the blade coating process, simple and controllable preparation of a one-pot method is achieved, and the prepared large-area side-chain cholesteric liquid crystal elastomer film has the force-induced discoloration and thermochromism dual response characteristics and is suitable for large-scale production. Wide application prospects are shown in the fields of color-changing materials, strain sensing, intelligent anti-counterfeiting, soft robots and the like, a new thought is provided for controllable preparation of high-performance intelligent response materials, and a new technical route is opened up for manufacturing of large-area customizable functional films.

The invention relates to pH-ROS (potential of hydrogen) double-response type drug-loading dendrimer nanogel as well as a preparation method and application thereof. According to the pH-ROS double-response type drug-loading dendrimer nanogel, G3-PBA-OH is obtained after a G3 PAMAM (polyamidoamine) dendrimer is subjected to functional modification; cross-linking with polyethylene glycol PBA-PEG-PBA with two ends grafted with phenylboronic acid to obtain dendrimer nanogel DNG, and further loading hypoxia activated chemotherapeutic drugs and cytokines on the DNG to obtain the hypoxia activated chemotherapeutic drug-loaded dendrimer nanogel. The DNG prepared by the invention has the characteristics of good biocompatibility, high drug loading rate, pH-ROS dual response and blood brain barrier penetration, provides a new thought for constructing a brain drug delivery nano platform, and can significantly improve the bioavailability of TPZ and IFN-gamma.

The invention discloses a preparation method of a non-Newtonian fluid-based temperature-shear dual response type ophthalmic sustained-release drug carrier, and belongs to the technical field of ophthalmic medicines. The preparation is composed of a dispersed phase (a temperature response type targeting nano-drug carrier) and a continuous phase (a non-Newtonian fluid matrix), wherein the mass fraction of the dispersed phase in the continuous phase is 0.5-2%. The temperature response type targeted nano-drug carrier is of a core-shell two-layer structure, the core is composed of a PLGA-PEG copolymer and an active drug, the shell is formed by grafting poly N-isopropylacrylamide (PNIPAM) and hyaluronic acid, and the lowest critical solution temperature (LCST) of the PNIPAM is 35-37 DEG C; the non-Newtonian fluid matrix is a pseudoplastic fluid, is composed of Carbomer 940 and triethanolamine, and has a shear thinning characteristic. The preparation method comprises the following three steps: preparation of the temperature response type targeting nano-drug carrier, preparation of the non-Newtonian fluid matrix and low-speed dispersion and compounding of the two. According to the invention, shear-response convenient administration, temperature-response precise drug release and long-acting retention synergism are realized, the bioavailability of the drug and the compliance of a patient are remarkably improved, the stability is excellent, the preparation process is simple and controllable, and the preparation method is suitable for long-acting targeted therapy of chronic eye diseases such as allergic conjunctivitis, chronic xerophthalmia, glaucoma and the like.

The application belongs to the field of drug delivery carriers and chemotherapy drugs, and particularly relates to a polymer with a GSH / ROS dual response mechanism, a preparation method and application thereof, and a lipid nanoparticle. The polymer has a GSH / ROS dual response mechanism, and a chemical structure general formula is as shown in the following: A-R-B; A is a first chemical structure with cholesterol or a derivative thereof; R is a second chemical structure with GSH response; and B is a third chemical structure as shown in formula I. Thus, the application endows the polymer with a GSH / ROS dual response mechanism through chemical structure design, and further applies the polymer to a drug delivery system and tumor synergistic treatment, so as to realize a multi-modal synergistic treatment strategy based on the redox dual-response lipid nanoparticle, and provide a new technical scheme with a significant synergistic enhancement effect for malignant tumor treatment.

The invention belongs to the technical field of catalytic degradation, and particularly relates to a Z-type catalyst ZnCo2O4 / FeCo2O4 which is synthesized on the basis of a sol-gel method and has microwave-ultrasonic double response activity as well as a preparation method and application of the Z-type catalyst ZnCo2O4 / FeCo2O4. The ZnCo2O4 / FeCo2O4 nanoparticle catalyst is obtained by adopting a sol-gel method, and antibiotics are degraded by combining a microwave-ultrasonic synergistic effect. As a new method for treating the antibiotic wastewater, the method has the advantages of high degradation efficiency, high speed, low cost, no secondary pollution and the like, is suitable for large-scale treatment of the antibiotic wastewater, and can quickly and thoroughly degrade the antibiotic wastewater in a short time.

The application discloses a FRET fluorescent probe with dual response to acetylcholinesterase and viscosity, a preparation method and application thereof, wherein the structure of the FRET fluorescent probe is shown in the following formula: The fluorescent probe is based on a fluorescence resonance energy transfer (FRET) mechanism, responds to acetylcholinesterase (AChE) at a short wave of 520 nm, and the detection limit is as low as 0.104 U / L, and responds to viscosity at a long wave of 680 nm, and the wavelength difference is as high as 160 nm, and the dual-channel response has no crosstalk. Cell toxicity test shows that the probe has good biocompatibility, and confocal fluorescence microscopic imaging experiment shows that the probe has good light stability for cells, has the ability of simultaneously monitoring the concentration change of AChE in cells and the viscosity fluctuation of cells, and is suitable for confocal fluorescence imaging for tracing the concentration change of AChE in cells and the viscosity fluctuation.

The present invention discloses a dual-responsive quercetin-caffeic acid phenethyl ester lipid composite gel and its preparation method and application. The present invention first uses microemulsion-lipid cascade drug delivery technology to co-load quercetin and caffeic acid phenethyl ester into liposomes, and then distributes the liposomes in a dual-responsive gel composed of chitosan, poloxamer 407 and poly-N-isopropylacrylamide to construct a dual-responsive quercetin-caffeic acid phenethyl ester lipid composite gel. The composite gel has a temperature-sensitive and pH-sensitive dual-responsive performance, and after administration, quercetin can be preferentially released to achieve rapid anti-inflammatory effects, and then caffeic acid phenethyl ester is released to promote osteogenic differentiation in the periodontal part, which can synergistically play the therapeutic effects of eliminating periodontal tissue inflammation and promoting alveolar bone repair, and provides a new preparation for the treatment of periodontitis.

The invention discloses a hypoxia and pH dual-response nano-carrier, a drug-loaded nanoparticle and application of the drug-loaded nanoparticle, and belongs to the technical field of biological medicine. According to the invention, p-formylbenzoic acid, nonaethylene glycol and azo p-aniline are subjected to a reaction to obtain the nano-carrier with moderate particle size and low oxygen and pH dual response, and the nano-carrier specifically targets a tumor site and then specifically releases drugs to reduce toxic and side effects; meanwhile, after the nano-carrier responds, benzaldehyde groups are released and are covalently connected with proteins on a lysosome membrane, so that the structure and activity of the proteins are changed, the lysosome membrane is broken and the permeability is increased after the proteins are denatured, and the nano-carrier cannot be discharged out of the cell, so that the intracellular drug concentration is greatly improved, and the drug effect is improved. In addition, the drug loading capacity of the nano-carrier is high, so that the nano-carrier has a relatively good application prospect.

The application discloses a dual-response foam stabilizer and a preparation method thereof, and belongs to the technical field of oil field chemicals. The foam stabilizer comprises a core layer and a responsive copolymer shell layer coated on the outer surface of the core layer; the core layer is composed of porous cellulose microspheres, silica grown in the channels of the porous cellulose microspheres and on the surface of the microspheres, and amphoteric surfactant grafted on the surface of the silica; and the responsive copolymer shell layer is obtained by copolymerization of N-isopropyl acrylamide, dimethylaminoethyl methacrylate and a silane coupling agent containing a double bond. After the porous cellulose microspheres are modified by epoxidation and carboxymethylation, the silica is grown in the channels and on the surface of the microspheres in situ, efficient grafting of the amphoteric surfactant is realized through amination modification, and finally, the copolymer shell layer with temperature / pH dual response is coated on the surface of the core layer, so that the foam stabilizer has the dual response capability of temperature response and pH response, and has excellent foam stabilizing performance in a complex oil reservoir environment.

The invention discloses environment response type hydrogel and a preparation method and application thereof, and belongs to the technical field of intelligent hydrogel and microchannel control. Stimuli response type hydrogel monomers and a water-phase dispersing agent are used as raw materials, a linear molecular chain is formed under the action of a free radical thermal initiator, and then the environment response type hydrogel is prepared. After the water-phase dispersing agent generates free radicals, graft polymerization is carried out on molecules of the stimuli-responsive hydrogel monomer under the action of the cross-linking agent, in the polymerization process, carbon-carbon double bonds of the cross-linking agent are broken and react with the water-phase dispersing agent and the stimuli-responsive hydrogel monomer, a cross-linked structure is formed, and the environment-responsive hydrogel is obtained. The environment response type hydrogel prepared by the invention has a tri-crosslinked network structure, has a pH and temperature dual-response function, is high in response speed and high in accuracy, and shows hysteresis in the response process.

The invention discloses a dual response type intelligent micro-capsule, an anti-icing insulator coating and a preparation process of the anti-icing insulator coating. The micro-capsule adopts a PDMAEMA / ZIF-8 hybrid composite material as a capsule wall, and hydrophobic small molecules and a repairing agent are encapsulated in the micro-capsule. The capsule wall has hierarchical response characteristics: hydrophobic molecules are slowly released daily to maintain super-hydrophobicity; the early warning protection effect is achieved through accelerated release in a weak acid environment; and when strong acid or mechanical damage occurs, the repair agent is broken and released to realize rapid self-healing repair. The microcapsule is used as a functional filler to be compounded with matrixes such as epoxy modified organic silicon resin and the like, and is coated on the surface of an insulator by adopting a spraying and stepped curing process. The problems that the hydrophobic performance of a traditional coating is irreversibly attenuated and the repairing mechanism is single are effectively solved, integrated cooperation of long-acting dynamic maintenance, environment early warning and active repairing is achieved, the anti-icing capacity of an insulator in a severe environment is remarkably improved, and the service life of the insulator in the severe environment is remarkably prolonged.

The application provides a gold nano drug delivery system with pH / NIR-II dual response characteristics and a preparation method thereof, and is prepared by sequentially preparing a gold nanocage (AuNC), a mesoporous silica coated AuNC (AuNC@mSiO2), an amino modified AuNC@mSiO2 (AuNC@mSiO2-NH2), a drug or dye loaded AuNC@mSiO2-NH2 (AuNC@mSiO2-NH2 intersection drug / dye), a PAA coated AuNC@mSiO2-NH2 intersection drug / dye (AuNC@mSiO2@PAA), and finally modifying with PEG and iRGD to obtain the gold nano drug delivery system ASPPR with a core-shell-membrane sandwich structure; the gold nano drug delivery system can realize precise cooperation of photothermal effect and mTOR inhibition in time and space, targets tumor to deliver an mTOR inhibitor first, restores antigen presentation, and then carries out photothermal therapy, so that better treatment conditions are provided for the photothermal therapy, and a combined treatment strategy is optimized.

This invention discloses a dual-response phase change hydrogel material for battery thermal management and its preparation method. The material is composed of water, N-isopropylacrylamide, polyvinyl alcohol, polyethylene glycol, graphene, a crosslinking agent, and an initiator in specific mass percentages. Its core feature is its dual-response characteristics of temperature and pressure: in terms of temperature response, the material undergoes a reversible solid-liquid phase change at approximately 35.2℃ for daily temperature control, and suppresses thermal runaway through a strong endothermic phase change in the 60-80℃ range; in terms of pressure response, the material possesses a piezoresistive effect, which can sensitively detect changes in internal battery pressure and provide early warning. This material also exhibits high thermal conductivity (≥3.7 W / (m·K)), excellent structural stability, and mechanical properties. Its preparation method mainly includes mixing the components, heating and dissolving, mold casting, and ultraviolet curing. This material is particularly suitable for intelligent battery thermal management in electric vehicles, energy storage systems, and other fields, and can significantly improve the safety and reliability of the system.

The invention discloses a pH / temperature dual response type core-shell structure charcoal composite slow-release carbon source as well as a preparation method and application thereof, and belongs to the technical field of functional materials and water body remediation. The method comprises the following steps: dispersing biochar and activated carbon felt fragments in deoxidized water, adding a FeCl2 solution, and slowly dropwise adding a NaBH4 solution for reaction to obtain a composite material; dipping the composite material in a carbon source solution prepared by dissolving starch and sodium acetate in hot water, oscillating and adsorbing at constant temperature, and drying to obtain a core precursor; the preparation method comprises the following steps: dissolving gelatin and sodium alginate in water, sequentially adding N-isopropylacrylamide, N, N '-methylene bisacrylamide and ammonium persulfate, introducing N2 to remove oxygen, and performing prepolymerization to prepare a prepolymerization solution; dispersing the core precursor in the pre-polymerization solution, and dropwise adding the slurry into a CaCl2 cross-linking bath; and reacting and collecting particles to obtain a final product. The system can respond to changes of pH and temperature of a water body environment, intelligently regulate and control a carbon source release behavior, and synergistically remove nitrate, heavy metals and organic pollutants.

The application discloses an intelligent woven material with wet-pH dual response characteristics and a preparation method and application thereof, and the method is as follows: preparing a high-concentration RSF spinning solution and wet spinning, then performing internal microstructure regulation on the semi-coagulation state fiber, so that the internal structure is directionally and orderly arranged and the proportion of the crystallization region and the amorphous region is adjusted; then the fiber is sent into a spinning coagulation bath to obtain an RSF fiber; the RSF fiber is woven to obtain an RSF woven material with a humidity response expansion rate of 0.5% to 5.0%; and the RSF woven material is surface coated and modified by using an alizarin solution, so that the material can present sharp color change in the range of pH=3 to 11, and finally the intelligent woven material with the wet-pH dual response characteristics is prepared. The application can effectively match the dynamic tension demand of a wound tissue, realizes visual early warning of a concealed infection, and has wide clinical application and industrialization prospect in the field of intelligent wound repair.

The invention discloses a preparation method of a temperature-ultraviolet illumination dual response type functional polymer. The preparation method specifically comprises the following steps: preparing a macromolecular initiator PEG2-ABCPA; preparing a p-styryl methyl diethanolamine borate monomer VMAB (vinyl methyl amine borate); the preparation method comprises the following steps: carrying out a free radical polymerization reaction on a styryl methyldiethanolamine borate monomer VMAB and 7-(4-vinylbenzyloxy)-4-methylcoumarin VBC by using a macromolecular initiator PEG2-ABCPA to obtain a block copolymer, namely the temperature-ultraviolet irradiation dual response type functional polymer. The polymer not only has a unique amphiphilic property, but also shows dual responsiveness to temperature and ultraviolet irradiation, so that the polymer shows a wide application prospect in the fields of drug controlled release, intelligent materials, photoelectric devices and the like.

The invention relates to the technical field of optical window surface functional coatings, in particular to a method for constructing a waterproof film layer on the surface of an optical window component and optical equipment. The method for constructing the waterproof film layer on the surface of the optical window component comprises the following steps: providing the optical window component; preprocessing the surface of the optical window component to improve the surface energy of the optical window component; providing a temperature and humidity dual response type polymer coating; and carrying out wet-temperature induced spin coating on the surface of the pretreated optical window component to form a film. The waterproof film layer constructed by the invention has excellent waterproof, light-transmitting and environment-adaptive performances, and is suitable for application scenes such as vehicle-mounted, security and industrial cameras.

This invention discloses three methods for reacting with Fe 3+ and Cr 3+ This invention relates to thiophene-containing probes with dual responses and their applications, belonging to the field of organic small molecule fluorescent probes. The probes are labeled FS-1, FS-2, and FS-3. Specifically, probe FS-1, under an excitation spectrum of 555 nm in acetonitrile solution, reacts with Fe... 3+ and Cr 3+ The binding caused a dramatic increase in fluorescence intensity at 584 nm; the FS-2 probe pair, in acetonitrile solution, under an excitation spectrum of 530 nm, reacted with Fe... 3+ and Cr 3+ The binding caused a sharp increase in fluorescence intensity at 555 nm; the FS-3 probe, in acetonitrile solution, under an excitation spectrum of 560 nm, reacted with Fe... 3+ and Cr 3+ The binding caused a sharp increase in fluorescence intensity at 584 nm in the fluorescence spectrum. All three probes were effective against Fe. 3+ and Cr 3+ It has high sensitivity, which is beneficial for detecting food containing these heavy metal ions and for playing a role in environmental monitoring.

The application discloses a photothermal dual-driven logic device based on ferroelectric materials and a preparation method thereof. The photothermal dual-driven logic device comprises a hemispherical substrate and a plurality of detection units arranged in the hemispherical substrate. The photothermal detection unit is composed of a first detector ferroelectric material A and a second detector ferroelectric material B in series. The first detector and the second detector are used to receive a thermal signal and a light signal respectively. The dual response of the ferroelectric material to the thermal signal and the light signal is used to realize logic operation. Compared with a traditional logic device, the device successfully utilizes the light and thermal signals in the natural environment to realize the XOR operation, has lower energy consumption, is simple, has the characteristics of collecting light and thermal signals in different directions, and has better application prospects in the light field and the thermal radiation field.

The application discloses a dual-response co-delivery nano platform for enhancing the radiotherapy effect on tumors, a preparation method and application thereof. The nano platform is formed by coordination self-assembly of metformin and metal cations, can produce dual responses to the low pH and high glutathione (GSH) level unique in the tumor microenvironment, realizes specific release of copper ions and metformin. The released metformin realizes radiotherapy sensitization by regulating mitochondrial respiratory metabolism. Meanwhile, radiotherapy up-regulates the expression of copper death-related proteins FDX1 and LIAS, can synergistically enhance the copper death pathway mediated by copper ions, causes immunogenic death of tumors, and produces a strong immune activation effect to inhibit tumor growth and recurrence and metastasis. The application provides a safe and effective new strategy for overcoming tumor radiotherapy resistance and immunosuppression.

The application discloses a kind of water power and pollutant dual response type nano repair materials and its application;Nano repair material has core-shell-outer layer structure, core provides repair function;Inner shell layer can perceive and respond target pollutant concentration, regulate active release;Outer shell layer can respond groundwater flow rate (shear force), regulate particle migration behavior.Nano repair material of the application can realize "low pollution area stable migration, high pollution area efficient activation", solve the problem of short migration distance of traditional nano repair material, non-target consumption fast, especially suitable for repairing complex groundwater flow affected organic pollution plume.The simultaneously provided repair method and repair system realize the controllability and intelligentization of repair process.

The invention discloses a dual-response fluorescent probe for ferrous ions and viscosity in a Parkinson's disease model, which is an off-on type fluorescent probe, can well realize dual response to ferrous ions and viscosity, and has the advantages of strong specificity, low background interference, high detection sensitivity, emission wavelength, better biocompatibility, low biological background fluorescence and the like. The fluorescent probe is successfully applied to fluorescence imaging in living cells and brain tissues of nematodes and drosophila melanogaster. The invention further discloses a preparation method and application. The preparation method is easy to operate and mild in condition. The fluorescent probe is successfully applied to biological systems including living cells, caenorhabditis elegans and drosophila melanogaster, and ferrous ion and viscosity level detection is successfully carried out by using a confocal microscope.

The invention belongs to the technical field of pipeline repair materials, and particularly relates to photocuring-moisture curing dual-response type pipeline lining repair resin and a synthesis method thereof, a lining hose and a preparation method and a construction method thereof. The repair resin comprises the following components in parts by weight: 40-60 parts of matrix resin A; 20 to 35 parts of matrix resin B; 10 to 20 parts of a reactive diluent; 1.5 to 3.0 parts of a photoinitiator A; 0.5 to 1.5 parts of a photoinitiator B; 0.05 to 0.2 part of a moisture sensitive accelerant; 0.5 to 2.0 parts of a coupling agent; 1.0 to 3.0 parts of a thixotropic agent; 0.2 to 0.5 part of an antioxidant; wherein the matrix resin A is an aliphatic polyurethane acrylate prepolymer; the matrix resin B is an isocyanate terminated polyether prepolymer; the photoinitiator A is 2, 4, 6-trimethylbenzoyl-diphenyl phosphine oxide; and the photoinitiator B is 1-hydroxycyclohexyl phenyl ketone. The invention provides photocuring-moisture curing dual-response type pipeline lining repairing resin and a synthesis method thereof, a lining hose and a preparation method and a construction method thereof.

The present invention discloses a magnetic vibration dual-response flower-shaped soft robot, comprising a petal-like structure, a deformation actuation system, a support mechanism, and a torus-like structure. The petal-like structure comprises a rotating wrapped soft skeleton and a thin film elastic body structure; the deformation braking system comprises a magnetorheological elastomer (MRE) and a liquid capsule; the support mechanism is mainly used to connect the petal-like structure, the deformation actuation system, and the torus-like structure; the torus-like structure comprises a torus-shaped cavity with two ends open, a non-magnetic metal vibrator, an elastic film, and a one-way valve. The magnetorheological elastomer contracts and deforms under the action of an external magnetic field in any direction, thereby driving the reversible deformation of the petal structure of the soft robot; the confined fluid in the cavity of the torus-like structure exhibits anisotropic mechanical propulsion behavior under an external vibration field. The purpose of the present invention is to develop a soft robot that can complete controllable movement in a living body and has good biocompatibility through biomimetic design.

The application discloses an intelligent active composite film with fresh-keeping and monitoring functions and a preparation method and application thereof. The preparation method comprises the following steps: limiting and intercepting thymol by spirulina to obtain spirulina loaded with thymol; coating the spirulina loaded with thymol by carboxymethyl chitosan to prepare an intelligent fragrance micro-reactor with pH / humidity dual response characteristics; and performing film forming treatment on a film forming liquid containing konjac glucomannan, blueberry anthocyanin, the intelligent fragrance micro-reactor and water to prepare the intelligent active composite film with the fresh-keeping and monitoring functions. The intelligent active composite film can realize fresh-keeping through active anti-corrosion intervention, has the in-situ freshness real-time diagnosis function and has a good application prospect in novel green food packaging materials.