22 results about "Thermosensitive polymer" patented technology

The invention discloses a photobleached all-polymer optical waveguide grating sensor and a preparation method thereof, and belongs to the technical field of polymer optical waveguide grating sensors. The preparation method comprises the following steps: carrying out hot stamping on a substrate sheet to obtain a substrate sheet with a groove; spin-coating photoresist on the substrate sheet to form a photoresist core layer; photoetching the photoresist core layer through double-beam interference to obtain the photoresist core layer with interference fringes; spin-coating a thermosensitive polymer cladding material on the photoresist core layer, covering the flexible substrate and then carrying out low-temperature thermocuring so as to bond the photoresist core layer and the flexible substrate; stripping the substrate sheet, exposing the photoresist core layer, covering the protective cladding, and curing to obtain a multi-layer composite device; and performing non-uniform post-baking on the multi-layer composite device to obtain the multi-layer composite device. According to the invention, the grating period can be changed under the condition that the grating mask is not replaced, and the cost of spectrum adjustment is greatly reduced.

Provided in the present application are a composite electrode active layer, an electrode sheet and a secondary battery. The composite electrode active layer comprises an active material layer and a composite insulating layer which are stacked in sequence, wherein the composite insulating layer comprises inorganic particles, a heat-resistant polymer and a thermosensitive polymer; the weight ratio of the inorganic particles to the heat-resistant polymer to the thermosensitive polymer is (50-100):(1-10):(5-50); the melting temperature of the heat-resistant polymer is 180-450ºC; and the softening temperature of the thermosensitive polymer is 80-120ºC.

This invention discloses a method for preparing a thermosensitive hemostatic gel, which is prepared by mixing a thermosensitive polymer solution with a solution of micron-sized polymer particles or microspheres with hemostatic function. The concentration of the solution of micron-sized polymer particles or microspheres with hemostatic function is 3-100 mg / mL; the concentration of the thermosensitive polymer solution is 200-450 mg / mL; the diameter of the micron-sized polymer particles or microspheres with hemostatic function is 300-900 micrometers; the gelation temperature of the thermosensitive hemostatic gel from a flowing liquid state to a solid state is greater than 15 degrees Celsius, and it is a flowing liquid state at temperatures below 15 degrees Celsius. Under the condition of warming up in response to the human body temperature, the flowing liquid hemostatic gel transforms into a solid hemostatic gel, thereby achieving the hemostatic function. The micron-sized polymer particles or microspheres in the thermosensitive hemostatic gel will not enter the damaged blood vessel during the hemostasis process.

We utilize high-quality-factor (high-Q) metasurfaces patterned either in or adjacent to electro-optical or thermo-optical materials such as lithium niobate, barium titanate, or thermally-sensitive polymers. The metasurface includes nanoantennas that act as dipole emitters; the particular structure and arrangement of nanoantennas can steer light to particular directions or focus light, The electromagnetic metasurface supports one or more guided mode resonances. The metasurface also includes a perturbation superposed on the metasurface features and configured to couple free-space radiation to the guided mode resonances.

A system for implantation by sterilisation techniques. A sterile implantation system comprising a heat-sensitive polymeric matrix that modifies its structure in the presence of a compressed gas or supercritical fluid to produce a solid or semi-solid with porosity greater than 60%.

The invention provides a secondary battery, a preparation method thereof and electric equipment. The secondary battery comprises one or more battery cells, the battery cell comprises a negative pole piece; the negative pole piece comprises a microcapsule; the microcapsule comprises an inner core and a shell layer arranged on the surface of the inner core; the inner core comprises a polymer, a lithium salt and chain carbonate; the shell layer comprises at least one of an organic piezoelectric material, a thermosensitive high polymer material and an acid response type high polymer material; the secondary battery satisfies at least one of the following conditions: 1) the piezoelectric constant d33 of the organic piezoelectric material is 10-50 pC / N; 2) the glass transition temperature of the thermosensitive polymer material is 50-100 DEG C, and 3) the acid response type polymer material comprises an acidolysis material which is degraded when the acid concentration is 3-120 ppm. The secondary battery provided by the invention has the advantages of less electrolyte consumption, good cycle performance and small internal resistance.

The invention discloses a preparation method of a two-phase release capsule preparation, and belongs to the field of capsule preparation. The method mainly comprises the following steps: dispersing meso-porous silicon nanoparticles in a drug solution, stirring, adsorbing the loaded drug, filtering, drying, sequentially adding a modified sodium alginate solution, a pore-foaming agent and a dichloromethane solution of cyclodextrin acyl chloride, and reacting to obtain a composite functionalized meso-porous silicon nano loaded drug; the preparation method comprises the following steps: dissolving sodium alginate and gelatin in deionized water according to a mass ratio of 3: 2, adding adamantane isocyanate for reaction, then adding a temperature-sensitive polymer, a pH responsive polymer, a cross-linking agent and an initiator, and uniformly stirring to obtain a precursor solution; by constructing an innovative two-phase release system, fusing a release regulation and control mechanism adaptive to multiple physiological environments, adopting an integrated preparation process and matching with a moisture-proof coating technology, the precision and the structural stability of two-phase release are remarkably improved, quick effect of a quick release phase and long-acting stable release of a slow release phase are realized, and the fluctuation range of blood concentration is greatly reduced.

This application relates to the field of textile technology, specifically disclosing a sweat-absorbing and expandable fabric and its preparation method. The sweat-absorbing and expandable fabric comprises the following raw materials: a base fiber and a modified fiber; the modified fiber is a functional fiber formed by grafting chitosan and a thermosensitive polymer onto the surface of polyester fibers using graft modification technology. The sweat-absorbing and expandable fabric of this application can be used to prepare quick-drying clothing, which has the advantages of quick-drying and good durability.

The application discloses a diaphragm, an electrochemical device and an electronic device, and belongs to the field of electrochemical energy storage. The diaphragm is used in the electrochemical device, and the diaphragm comprises a base film and a coating arranged on one side or both sides of the base film. The coating comprises a first coating and a plurality of second coatings arranged on the side of the first coating away from the base film. The plurality of second coatings are alternately arranged along the length direction of the first coating. The first coating comprises first inorganic particles and a heat-sensitive polymer. The melting point of the heat-sensitive polymer is 85 DEG C to 130 DEG C. The particle size Dv50 of the first inorganic particles is alpha. The particle size Dv50 of the heat-sensitive polymer is beta. Alpha and beta satisfy the following conditions: beta = alpha + n, 0.3 mu m <= alpha <= 7.1 mu m, and 0 <= n <= 0.2. The diaphragm can improve the cycle performance and thermal abuse performance of the electrochemical device.

This application provides a hydrogel wound dressing and its preparation method, comprising: a hydrogel layer, a support layer, and a protective layer. The hydrogel layer is prepared from the following raw material components in the following mass ratio: 10-15% polyvinylpyrrolidone, 5-8% polycaprolactone, 2-4% sodium carboxymethyl cellulose, 1-3% chitosan, 0.5-1.5% antibacterial agent, 0.1-0.3% antioxidant, 0.01-0.1% growth factor, 0.1-0.5% thermosensitive polymer, 0.05-0.15% graphene quantum dots, 0.5-1.5% self-healing polymer, 0.5-1.5% pH-sensitive material, 0.1-0.3% nano-titanium dioxide, and the balance being deionized water. The support layer is a porous polylactic acid film with a thickness of 0.1-0.3 mm. The protective layer is a breathable polyurethane film with a thickness of 0.2-0.4 mm. Through the synergistic effect of the antibacterial agent, nano-titanium dioxide, and graphene quantum dots, the antibacterial performance of the dressing is significantly improved.

A positive electrode sheet containing a high-safety heat-sensitive coating and a lithium-ion battery containing the positive electrode sheet are provided. The heat-sensitive coating includes a first conductive agent, a first binder, heat-sensitive polymer microspheres and an auxiliary agent, and has a conductive property at normal temperature and also has advantages of increasing a contact area between an active material and a current collector, improving the conductivity, and effectively reducing the polarization of battery and the like; when the use temperature of the positive electrode sheet reaches 120° C. and above, the heat-sensitive polymer microspheres will melt to form a plurality of continuous electron blocking layers, current blocking occurs in the coating, an internal blocking forms inside the battery, thereby preventing the occurrence of further thermal runaway of lithium-ion battery.

This invention relates to the field of biodetection technology, providing a logic-gated nanogel probe for live cell typing and its preparation method. The invention uses a thermosensitive polymer nanogel as a carrier, with its surface covalently modified with an antibody that specifically binds to the EGFR L858R mutant protein and a peptide nucleic acid that specifically binds to miR-21. Internally, it encapsulates a self-quenched fluorescent dye. The probe employs an AND logic gating design, triggering gel network dissociation and dye release to generate a fluorescent signal only when it simultaneously recognizes the EGFR L858R protein on the cell surface and captures miR-21 within the cell. This invention solves the problems of high false positive rates in existing single-target detection methods and the inability of traditional liquid biopsy techniques to perform simultaneous genotype-phenotype analysis in situ on live cells. It achieves highly specific and sensitive in situ interpretation of circulating tumor cells, and has significant application value in the field of precision diagnosis and treatment of lung cancer.

This invention belongs to the field of medical materials technology, specifically referring to a drug-loaded porous magnesium alloy bone scaffold and its preparation method. The drug-loaded porous magnesium alloy bone scaffold is composed of the following raw materials in parts by weight: 55 parts magnesium alloy, 6-10 parts corrosion inhibitor, 1 part drug-loaded gel, 2-4 parts antibacterial bone-promoting agent, and 3 parts gelatin. This invention achieves sustained drug release by fabricating magnesium alloy into microtubes and filling the interior with a drug-loaded hydrogel; gelatin is sprayed onto the surface and adhered through Mg-N coordination bonds, bonded to the corrosion inhibitor, and hot-pressed. The components form an interpenetrating network with the gelatin to enhance bonding and react with the magnesium alloy to form a protective film; simultaneously, Ca... 2+ The process initiates cross-linking of sodium alginate, forming a stable anti-corrosion barrier. Finally, an antibacterial and bone-promoting mixture containing modified chitosan and thermosensitive polymer is sprayed on. Through complexation reaction and temperature control, the bone-promoting components are evenly dispersed around the implant, improving tissue compatibility.

This invention relates to a textile composite finishing liquid and its preparation method, as well as Janus textiles with a gradient structure and their preparation method, belonging to the field of functional textile technology. The preparation method of the composite finishing liquid includes: obtaining component A by reacting raw materials containing a first hydroxyl-terminated polydimethylsiloxane, a second hydroxyl-terminated polydimethylsiloxane, and a crosslinking agent; reacting a two-dimensional material dispersion with a thermosensitive polymer to obtain a two-dimensional material grafted with the thermosensitive polymer; assembling the two-dimensional material grafted with the thermosensitive polymer into a monolayer film, and then grafting a hydrophobic silanol onto the other surface of the monolayer film to obtain thermosensitive nanosheets; mixing the thermosensitive nanosheets with an organic solvent to obtain component B; and mixing component A and component B to obtain the composite finishing liquid. Janus textiles prepared using this composite finishing liquid exhibit excellent wash durability, unidirectional moisture wicking, contact angle, and temperature responsiveness.

This invention belongs to the field of biomedical sensing and flexible electronics technology, and proposes a hydrogel electrode for long-term bioelectrical signal monitoring, its preparation method, and its application. The hydrogel electrode of this invention comprises a porous hydrogel and a network conductive layer embedded within the hydrogel, forming a three-dimensional mechanically interlocked structure. The average pore size of the hydrogel is 100 μm-500 μm, and its porosity is 60%-90%. The raw materials for preparing the hydrogel include the following components in parts by weight: 5-30 parts of a thermosensitive polymer, 0.5-15 parts of a conductive component, 5-40 parts of a water-retaining agent, 0.1-10 parts of an adhesive, and 0.01-2 parts of a crosslinking agent. Through multi-scale structural design and the synergistic effect of multiple components, the hydrogel electrode of this invention constructs a structure integrating a through-pore framework and a three-dimensional interlocked conductive network, achieving excellent comprehensive performance in terms of breathability, moisture retention, interfacial mechanics, and bioelectrical signal acquisition.

This invention belongs to the field of biomedical technology and provides a mussel adhesive protein and azelastine hydrochloride nasal thermosensitive gel, its preparation and application. The mussel adhesive protein and azelastine hydrochloride nasal thermosensitive gel includes an active ingredient and pharmaceutically acceptable excipients. The active ingredient is recombinant mussel adhesive protein mefp-5 subtype and azelastine hydrochloride. The excipients include a thermosensitive polymer, which is mixed with the active ingredient to form a thermosensitive gel system. This invention solves the technical problem that existing single-drug formulations cannot simultaneously provide rapid symptom relief and long-term mucosal barrier repair for allergic rhinitis by combining recombinant mussel adhesive protein mefp-5 subtype with mucosal repair function with azelastine hydrochloride, which has rapid anti-allergic effects. Pharmacodynamic studies have confirmed that the two active ingredients exhibit a significant synergistic effect (CDI < 0.7) in improving allergy symptoms, inhibiting inflammatory responses, and repairing the mucosal barrier.

This invention provides a thermosensitive physical hydrogel lyophilized formulation, its preparation method, and its application. The raw materials for preparing the thermosensitive physical hydrogel lyophilized formulation include a thermosensitive polymer, sodium hyaluronate, and phosphate buffer. The phase transition temperature of the thermosensitive polymer is 35±2℃. The molecular weight of the sodium hyaluronate is 2.2 million to 2.8 million, and its mass-to-volume ratio with the phosphate buffer is 3-12 mg:1 ml. This invention uses a specific molecular weight and dosage of sodium hyaluronate and a thermosensitive polymer to achieve rapid gelation transformation under physiological temperature conditions, forming an interpenetrating three-dimensional network structure with better structural stability, facilitating cell growth and repair, and extending degradation time, thus reducing the inconvenience of repeated injections. Furthermore, the lyophilized formulation can solve problems such as needle clogging, precipitation, degradation, and poor stability associated with microsphere products.

This invention discloses a recombinant type III humanized collagen gel and its preparation process, belonging to the fields of biomedicine and polymer materials. This gel aims to solve the problems of weak mechanical properties, short duration of action, and limited bioactivity in existing collagen gels. The key technical solution lies in the gel's dual-network interpenetrating structure, which includes a first network composed of enzymatically cross-linked recombinant type III humanized collagen, and a second network physically interpenetrating with the first network, composed of thermosensitive polymers (such as poloxamer). Preferably, the gel also encapsulates sustained-release nanoparticles loaded with growth factors (such as bFGF) to actively induce tissue regeneration. The preparation process involves mixing the components at low temperature, followed by a two-step method of enzymatic reaction and temperature response to sequentially form the first and second networks. The gel of this invention possesses excellent mechanical support, long-term stability, and active bioactivity, making it suitable for medical aesthetic filling and tissue repair applications.

Compositions and methods are provided for transplantation of cells to the body, utilizing a thermosensitive polymer that forms a gel when introduced onto tissue or into a cavity of the tissue, such as the eye.

This invention relates to the field of inorganic materials, specifically to a preparation process for electronic-grade antimony trioxide. The process involves dissolving antimony trichloride in anhydrous ethanol to obtain solution A; dissolving a thermosensitive polymer in deionized water and adjusting the pH to 9-10 with ammonia to obtain solution B; heating solution B to above 50°C; adding solution A to solution B; stirring the reaction; restoring to room temperature; collecting the product; washing; and drying. The antimony trioxide prepared by this invention exhibits excellent electrochemical performance and demonstrates superior cycle performance in lithium batteries.

This invention provides a moisture-permeable membrane, its preparation method, and its application. The moisture-permeable membrane includes a base membrane and hybrid particles distributed within the base membrane. The hybrid particles include thermosensitive polymer particles and gold nanomaterials distributed within the thermosensitive polymer particles. In this invention, the moisture-permeable membrane has a high water molecule transfer rate and good moisture permeability, which helps reduce the formation of condensate. Simultaneously, the moisture-permeable membrane responds rapidly to photothermal conversion; when condensate forms, it can be promptly and quickly removed from the membrane surface under certain stimuli, ensuring the membrane's performance.