49 results about "Thermosensitive polymer" patented technology

The invention discloses a core-shell nano-enzyme composite spray gel dressing and a preparation method and application thereof.The dressing comprises a component A prepared from sodium alginate, N-isopropylacrylamide PNIPAM, core-shell nano-enzyme and curcumin and a component B of a divalent metal salt solution, and the component A and the component B are sprayed at the same time to form the core-shell nano-enzyme composite spray gel dressing. The preparation method of the core-shell nano enzyme comprises the following steps: mixing potassium ferrocyanide, ferric trichloride and polyvinylpyrrolidone to obtain a Prussian blue nano particle precursor solution; carrying out ultrasonic emulsification treatment and replacement on the curcumin core solution and the Prussian blue nanoparticle precursor solution; and freeze-drying to obtain the core-shell nano-enzyme. Through rapid ionic crosslinking of sodium alginate and divalent metal ions and the temperature-sensitive phase change characteristic of the temperature-sensitive polymer poly (N-isopropylacrylamide), the gel dressing is rapidly formed, the damaged skin is effectively covered and protected, the excellent antioxidant, anti-inflammatory and antibacterial capabilities are achieved, and the healing cycle of the radiodermatitis wound can be remarkably shortened.

Disclosed is a modified polymer obtained by enclosing and / or grafting a non-thermosensitive polymer particle with a thermosensitive polymer, the modified polymer has a viscosity exhibiting a significant change at 40 to 90℃. Also disclosed is a polymer having a core-shell structure, wherein the core particle consists essentially of a non-thermosensitive polymer, and the shell is located on the outer surface of the core particle and consists essentially of a segment derived from a thermosensitive polymer, the polymer has a viscosity exhibiting a significant change at 40 to 90℃. Further disclosed is a method for preparing an aqueous dispersion of polymer. Still further disclosed is a coating composition comprising the above modified polymer, the above polymer, or the above aqueous dispersion of polymer, a substrate coated with the coating composition, as well as use of the modified polymer, the polymer, or the aqueous dispersion of polymer.

The invention discloses a photobleached all-polymer optical waveguide grating sensor and a preparation method thereof, and belongs to the technical field of polymer optical waveguide grating sensors. The preparation method comprises the following steps: carrying out hot stamping on a substrate sheet to obtain a substrate sheet with a groove; spin-coating photoresist on the substrate sheet to form a photoresist core layer; photoetching the photoresist core layer through double-beam interference to obtain the photoresist core layer with interference fringes; spin-coating a thermosensitive polymer cladding material on the photoresist core layer, covering the flexible substrate and then carrying out low-temperature thermocuring so as to bond the photoresist core layer and the flexible substrate; stripping the substrate sheet, exposing the photoresist core layer, covering the protective cladding, and curing to obtain a multi-layer composite device; and performing non-uniform post-baking on the multi-layer composite device to obtain the multi-layer composite device. According to the invention, the grating period can be changed under the condition that the grating mask is not replaced, and the cost of spectrum adjustment is greatly reduced.

Provided in the present application are a composite electrode active layer, an electrode sheet and a secondary battery. The composite electrode active layer comprises an active material layer and a composite insulating layer which are stacked in sequence, wherein the composite insulating layer comprises inorganic particles, a heat-resistant polymer and a thermosensitive polymer; the weight ratio of the inorganic particles to the heat-resistant polymer to the thermosensitive polymer is (50-100):(1-10):(5-50); the melting temperature of the heat-resistant polymer is 180-450ºC; and the softening temperature of the thermosensitive polymer is 80-120ºC.

This invention discloses a method for preparing a thermosensitive hemostatic gel, which is prepared by mixing a thermosensitive polymer solution with a solution of micron-sized polymer particles or microspheres with hemostatic function. The concentration of the solution of micron-sized polymer particles or microspheres with hemostatic function is 3-100 mg / mL; the concentration of the thermosensitive polymer solution is 200-450 mg / mL; the diameter of the micron-sized polymer particles or microspheres with hemostatic function is 300-900 micrometers; the gelation temperature of the thermosensitive hemostatic gel from a flowing liquid state to a solid state is greater than 15 degrees Celsius, and it is a flowing liquid state at temperatures below 15 degrees Celsius. Under the condition of warming up in response to the human body temperature, the flowing liquid hemostatic gel transforms into a solid hemostatic gel, thereby achieving the hemostatic function. The micron-sized polymer particles or microspheres in the thermosensitive hemostatic gel will not enter the damaged blood vessel during the hemostasis process.

This invention discloses a porous carbon-based dual-drug-loaded nanomaterial for sustained release. The material uses a thermosensitive polymer as a matrix and cellulose nanocrystals modified with cationic surfactants as a reinforcing phase, loading both hydrophilic and hydrophobic drugs. This material can be used to prepare therapeutic drugs for gynecological diseases and infertility, as well as drug delivery devices. Furthermore, this invention provides a uterine scaffold prepared using this material, which can be fabricated using 3D printing technology. Utilizing the PNIPAm hydrogel network and its temperature-responsive properties, hydrophilic drugs can be loaded at low temperatures. The high mechanical strength of CNC machining allows for the loading of hydrophobic drugs while improving the mechanical properties of the hydrogel matrix, thus solving the problems of easy detachment and bleeding in existing technologies.

The invention discloses a battery diaphragm and a secondary battery, and belongs to the technical field of batteries. The battery diaphragm provided by the invention comprises a base membrane and a thermosensitive coating laminated on the surface of at least one side of the base membrane, wherein the thermosensitive coating comprises the following components in percentage by mass: 20-50% of thermosensitive polymer and 45-80% of inorganic particles; a synthetic monomer of the thermosensitive polymer is selected from at least one of the following monomer compounds: at least one of a non-fluorine alkenyl monomer, an alkylene monomer, an unsaturated nitrile monomer, an olefine acid monomer and an ester monomer; the average particle diameter of the inorganic particles is 0.1 [mu] m to 10 [mu] m, and the Mohs hardness of the inorganic particles is 2.0 to 5.0. The thermal sensitive polymer and the inorganic particles in the thermal sensitive coating have a synergistic effect, so that the battery diaphragm not only has a thermal hole closing function, but also has high heat resistance, the thermal shrinkage rate of the battery diaphragm at a high temperature is reduced, and meanwhile, the puncture strength of the battery diaphragm is also improved.

We utilize high-quality-factor (high-Q) metasurfaces patterned either in or adjacent to electro-optical or thermo-optical materials such as lithium niobate, barium titanate, or thermally-sensitive polymers. The metasurface includes nanoantennas that act as dipole emitters; the particular structure and arrangement of nanoantennas can steer light to particular directions or focus light, The electromagnetic metasurface supports one or more guided mode resonances. The metasurface also includes a perturbation superposed on the metasurface features and configured to couple free-space radiation to the guided mode resonances.

The invention discloses thermo-sensitive polymer hydrogel as well as a preparation method and application thereof, and the polymer hydrogel comprises a temperature response type polymer monomer, cement hydration product nanoparticles and an initiator. The polymer hydrogel disclosed by the invention has excellent compressive strength and biocompatibility, so that cells can well grow and adhere to the polymer hydrogel; the polymer hydrogel also has drug loading and rapid drug release properties, and lays a foundation for the gel as a wound dressing.

The invention discloses a battery diaphragm, a preparation method thereof and a secondary battery, and belongs to the field of secondary batteries, and the battery diaphragm comprises a base membrane, a nanofiber layer and a thermosensitive layer which are stacked in sequence. The base film is prepared from polyethylene with the molecular weight of 1.5 million to 3 million. The thermosensitive layer comprises 5-10 parts of a thermosensitive polymer, 15-20 parts of first inorganic particles, 0.05-0.1 part of a first dispersing agent, 0.3-0.5 part of a first thickening agent, 2-5 parts of a first binder and 0.05-0.1 part of a first wetting agent, and the thermosensitive polymer is selected from polyethylene wax and / or an ethylene copolymer. The nanofiber layer comprises nanocellulose and second inorganic particles, and the nanocellulose is selected from at least one of cellulose microfibrils, nanocellulose crystals and bacterial nanocellulose; the inorganic particles are selected from at least one of boehmite, aluminum oxide, magnesium hydroxide, barium carbonate, magnesium carbonate and zirconium oxide. The diaphragm has low-temperature closed pores and high-temperature dimensional stability.

A system for implantation by sterilisation techniques. A sterile implantation system comprising a heat-sensitive polymeric matrix that modifies its structure in the presence of a compressed gas or supercritical fluid to produce a solid or semi-solid with porosity greater than 60%.

The application provides a heat-closed pore separator based on a surface grafting strategy and a preparation method and application thereof, and belongs to the technical field of lithium ion battery separator materials.The application forms a polydopamine modification layer on the surface of a polyolefin film, introduces a bromine initiator on the surface of the polydopamine modification layer, obtains the polyolefin film containing the bromine initiator on the surface, grafts a heat-sensitive polymer layer on the surface of the polyolefin film containing the bromine initiator, and obtains the heat-closed pore separator based on the surface grafting strategy.The heat-closed pore separator based on the surface grafting strategy can improve the safety performance of the battery while maintaining the electrochemical performance of the battery, the heat-closed pore separator can realize the heat-closed pore function at high temperature, the battery can operate at a safe temperature, and the heat runaway phenomenon caused by overheating of the battery can be effectively prevented.

The invention provides a secondary battery, a preparation method thereof and electric equipment. The secondary battery comprises one or more battery cells, the battery cell comprises a negative pole piece; the negative pole piece comprises a microcapsule; the microcapsule comprises an inner core and a shell layer arranged on the surface of the inner core; the inner core comprises a polymer, a lithium salt and chain carbonate; the shell layer comprises at least one of an organic piezoelectric material, a thermosensitive high polymer material and an acid response type high polymer material; the secondary battery satisfies at least one of the following conditions: 1) the piezoelectric constant d33 of the organic piezoelectric material is 10-50 pC / N; 2) the glass transition temperature of the thermosensitive polymer material is 50-100 DEG C, and 3) the acid response type polymer material comprises an acidolysis material which is degraded when the acid concentration is 3-120 ppm. The secondary battery provided by the invention has the advantages of less electrolyte consumption, good cycle performance and small internal resistance.

This invention discloses a supersonic drying system and dehydration method for particles, relating to the field of particle drying technology. The system includes a collection cylinder fitted outside an accelerating cylinder. By guiding thermosensitive polymer particles into a vortex flow field, they are suspended and spirally ascended under the dynamic balance of centrifugal force and airflow drag. The low-pressure environment generated by the vortex flow field lowers the boiling point of water on the particle surface, and combined with a heat-generating unit, moisture evaporation can be achieved at a relatively low temperature. Subsequently, a high-energy electron beam excited by a plasma generator promotes the migration and evaporation of moisture from the particles, enhancing the drying effect. After dehydration, the particles automatically detach from the vortex flow field due to density changes and enter the collection zone, while the nitrogen flow carries the evaporated water vapor into the discharge zone, achieving automatic separation of the particles and the nitrogen flow. This invention, through its unique structural design and particle motion drying process, is suitable for thermosensitive polymer particles, avoiding thermal degradation and achieving highly efficient particle drying.

A method for producing a nickel-phosphorus coating on a laminate comprising a heat-sensitive polymer substrate and an aluminum layer.

This invention relates to an ultrafast intelligent fungal capture agent, which is a core-shell nanostructure. The core is a magnetic nanoparticle, and the shell is a thermosensitive polymer. The surface of the thermosensitive polymer is coupled with substances that specifically bind to fungi. This ultrafast fungal capture agent exhibits rapid capture speed, successfully isolating approximately 75% or more of the fungi, which can then be immediately detected using SERS. The preparation method of this fungal capture agent is simple and mild, allowing for repeated recycling using an external magnetic field, and the fungal capture capacity remains largely unchanged. It is significantly economical for industrial applications and suitable for large-scale use. This fungal capture agent possesses intelligent capture and release behavior. By controlling the temperature, an intelligent and efficient fungal capture-detection process can be completed, reducing the entire process time to within 10 minutes, thus improving diagnostic speed and reducing patient mortality.

The invention belongs to the technical field of medical materials, and particularly relates to a drug-loaded porous magnesium alloy bone scaffold and a preparation method thereof.The drug-loaded porous magnesium alloy bone scaffold is prepared from, by mass, 55 parts of magnesium alloy, 6-10 parts of corrosion-resistant matter, 1 part of drug-loaded gel, 2-4 parts of antibacterial bone promoting matter and 3 parts of gelatin; the magnesium alloy is made into a micro tube, and the micro tube is filled with the drug-loaded hydrogel to realize drug sustained release; gelatin is sprayed on the surface, corrosion-resistant materials are attached through Mg-N coordinate bonds, hot pressing is carried out, and components of the corrosion-resistant materials and the gelatin form an interpenetrating network to enhance combination and react with the magnesium alloy to form a protective film. Meanwhile, Ca < 2 + > initiates crosslinking of sodium alginate to form a stable corrosion-resistant barrier; and finally, an antibacterial bone-promoting mixed solution containing modified chitosan and a temperature-sensitive polymer is sprayed, bone-promoting components are uniformly dispersed around the implant through a complex reaction and temperature control, and tissue compatibility is improved.

The invention discloses a preparation method of a two-phase release capsule preparation, and belongs to the field of capsule preparation. The method mainly comprises the following steps: dispersing meso-porous silicon nanoparticles in a drug solution, stirring, adsorbing the loaded drug, filtering, drying, sequentially adding a modified sodium alginate solution, a pore-foaming agent and a dichloromethane solution of cyclodextrin acyl chloride, and reacting to obtain a composite functionalized meso-porous silicon nano loaded drug; the preparation method comprises the following steps: dissolving sodium alginate and gelatin in deionized water according to a mass ratio of 3: 2, adding adamantane isocyanate for reaction, then adding a temperature-sensitive polymer, a pH responsive polymer, a cross-linking agent and an initiator, and uniformly stirring to obtain a precursor solution; by constructing an innovative two-phase release system, fusing a release regulation and control mechanism adaptive to multiple physiological environments, adopting an integrated preparation process and matching with a moisture-proof coating technology, the precision and the structural stability of two-phase release are remarkably improved, quick effect of a quick release phase and long-acting stable release of a slow release phase are realized, and the fluctuation range of blood concentration is greatly reduced.

This application relates to the field of textile technology, specifically disclosing a sweat-absorbing and expandable fabric and its preparation method. The sweat-absorbing and expandable fabric comprises the following raw materials: a base fiber and a modified fiber; the modified fiber is a functional fiber formed by grafting chitosan and a thermosensitive polymer onto the surface of polyester fibers using graft modification technology. The sweat-absorbing and expandable fabric of this application can be used to prepare quick-drying clothing, which has the advantages of quick-drying and good durability.

The application discloses a diaphragm, an electrochemical device and an electronic device, and belongs to the field of electrochemical energy storage. The diaphragm is used in the electrochemical device, and the diaphragm comprises a base film and a coating arranged on one side or both sides of the base film. The coating comprises a first coating and a plurality of second coatings arranged on the side of the first coating away from the base film. The plurality of second coatings are alternately arranged along the length direction of the first coating. The first coating comprises first inorganic particles and a heat-sensitive polymer. The melting point of the heat-sensitive polymer is 85 DEG C to 130 DEG C. The particle size Dv50 of the first inorganic particles is alpha. The particle size Dv50 of the heat-sensitive polymer is beta. Alpha and beta satisfy the following conditions: beta = alpha + n, 0.3 mu m <= alpha <= 7.1 mu m, and 0 <= n <= 0.2. The diaphragm can improve the cycle performance and thermal abuse performance of the electrochemical device.

This application provides a hydrogel wound dressing and its preparation method, comprising: a hydrogel layer, a support layer, and a protective layer. The hydrogel layer is prepared from the following raw material components in the following mass ratio: 10-15% polyvinylpyrrolidone, 5-8% polycaprolactone, 2-4% sodium carboxymethyl cellulose, 1-3% chitosan, 0.5-1.5% antibacterial agent, 0.1-0.3% antioxidant, 0.01-0.1% growth factor, 0.1-0.5% thermosensitive polymer, 0.05-0.15% graphene quantum dots, 0.5-1.5% self-healing polymer, 0.5-1.5% pH-sensitive material, 0.1-0.3% nano-titanium dioxide, and the balance being deionized water. The support layer is a porous polylactic acid film with a thickness of 0.1-0.3 mm. The protective layer is a breathable polyurethane film with a thickness of 0.2-0.4 mm. Through the synergistic effect of the antibacterial agent, nano-titanium dioxide, and graphene quantum dots, the antibacterial performance of the dressing is significantly improved.

The invention discloses a synergistic confinement high-ductility metal foil anti-oxidation breaking method which is suitable for size reduction and oxidation inhibition of copper foil and other materials, and the method comprises the following steps: forming a nano-scale anti-oxidation protection layer of silver, nickel, graphene and the like, and embedding and fixing the metal foil in a hardenable and removable confinement substrate (such as ice, water sugar, thermosensitive polymer and the like), so that the metal foil can be prevented from being broken; then, mechanical crushing processes such as ball milling, crushing and grinding are adopted, a substrate is removed through washing, hot melting or solvent extraction, and metal foil fragments which are uniform in particle size, regular in morphology and excellent in oxidation resistance are obtained; the method obviously improves the crushing efficiency and the size control capability, effectively reduces the oxidation degree, has green, environment-friendly and industrial amplification potential, and is widely applicable to preparation of functional materials such as heat-conducting fillers and flexible electronic and electromagnetic shielding materials.

Herein disclosed is a method of printing a 3D freeform structure in an embedding medium. The method includes providing an ink composition in a nozzle, wherein the ink composition includes a thermoplastic, a non-thermoplastic, a thermally degradable polymer, and / or a thermosensitive polymer, dissolved in a solvent; dispensing the ink composition through a nozzle into the embedding medium to precipitate a printed structure from the ink composition, wherein the ink composition exits from the nozzle directly in the embedding medium; and maintaining the printed structure in the embedding medium until the immersion precipitation is completed for forming the 3D freeform structure. A system operable to carry out the method is also disclosed. The system includes a syringe coupled to a nozzle.

The application provides a lithium extraction adsorbent and a preparation method and application thereof, and the preparation method comprises the following steps: (1) mixing an aluminum salt and lithium chloride with a solvent, adding an alkali liquor for one-step reaction to obtain a precursor; (2) mixing the precursor, cysteine, 3-(trimethoxysilyl) methyl propyl methacrylate and a solvent, and performing two-step reaction to obtain a grafted precursor; (3) mixing the grafted precursor, N-isopropyl acrylamide, an initiator and a crosslinking agent with a solvent, and performing three-step reaction to obtain the lithium extraction adsorbent. The ordered vacancy type layered structure formed by inserting LiCl into Al(OH)3 is modified by grafting a sulfonic acid group and compounding a heat-sensitive polymer, and the prepared adsorbent can adjust the pore size according to the desorption temperature, so that the desorption rate of Li+ of the adsorbent is increased, and the lithium extraction efficiency is improved.

A positive electrode sheet containing a high-safety heat-sensitive coating and a lithium-ion battery containing the positive electrode sheet are provided. The heat-sensitive coating includes a first conductive agent, a first binder, heat-sensitive polymer microspheres and an auxiliary agent, and has a conductive property at normal temperature and also has advantages of increasing a contact area between an active material and a current collector, improving the conductivity, and effectively reducing the polarization of battery and the like; when the use temperature of the positive electrode sheet reaches 120° C. and above, the heat-sensitive polymer microspheres will melt to form a plurality of continuous electron blocking layers, current blocking occurs in the coating, an internal blocking forms inside the battery, thereby preventing the occurrence of further thermal runaway of lithium-ion battery.

This invention relates to a method for preparing an irradiated thermosensitive ruthenium-ethylenediaminetetraacetic acid (EDTA) imprinted polymer. The method first uses reversible addition-fragmentation chain transfer polymerization to prepare a linear thermosensitive polymer, poly(N,N-diethylacrylamide). Then, the poly(N,N-diethylacrylamide) is used as a RAFT reagent to synthesize a thermosensitive block with acrylamide. Finally, the thermosensitive block is co-dissolved in an aqueous methanol solution with acrylamide, acrylic acid, N,N-methylenebisacrylamide, and a ruthenium-EDTA complex. The thermosensitive block is then introduced through cobalt-60 irradiation solution polymerization to obtain the thermosensitive ruthenium-EDTA complex imprinted polymer. This invention is characterized by its short preparation time, environmental friendliness, and high production efficiency. The adsorbent prepared using the obtained thermosensitive ruthenium-EDTA imprinted polymer exhibits a rapid adsorption rate.

This invention relates to the field of biodetection technology, providing a logic-gated nanogel probe for live cell typing and its preparation method. The invention uses a thermosensitive polymer nanogel as a carrier, with its surface covalently modified with an antibody that specifically binds to the EGFR L858R mutant protein and a peptide nucleic acid that specifically binds to miR-21. Internally, it encapsulates a self-quenched fluorescent dye. The probe employs an AND logic gating design, triggering gel network dissociation and dye release to generate a fluorescent signal only when it simultaneously recognizes the EGFR L858R protein on the cell surface and captures miR-21 within the cell. This invention solves the problems of high false positive rates in existing single-target detection methods and the inability of traditional liquid biopsy techniques to perform simultaneous genotype-phenotype analysis in situ on live cells. It achieves highly specific and sensitive in situ interpretation of circulating tumor cells, and has significant application value in the field of precision diagnosis and treatment of lung cancer.

The invention is applicable to the technical field of busbar bushings, and provides a flame-retardant heat-shrinkable busbar bushing and a preparation method thereof.The flame-retardant heat-shrinkable busbar bushing comprises the following raw materials: a vinyl polymer, an antioxidant, a lubricant, aerogel powder, a phosphorus-silicon hybrid cage type oligomer, zinc ion crosslinked nitrile rubber, modified nanocellulose and color masterbatch; wherein the aerogel powder is subjected to functionalization treatment by loading a flame-retardant microcapsule, and the functionalization treatment specifically comprises the following steps: a) grafting a thermosensitive polymer valve at an aerogel pore inlet; the aerogel powder is adopted as a lightweight framework and a flame retardant carrier, so that the flame retardance and the mechanical property of the casing pipe are improved; by adding the phosphorus-silicon hybrid cage type oligomer, the flame retardance is further improved; by adding zinc ion crosslinked nitrile rubber, the mechanical property is improved; and by adding the modified nanocellulose, disulfide bond dynamic exchange has a self-repairing function, and a nano-enhanced network further improves the mechanical properties.