31 results about "Liver surgery" patented technology

Disclosed are compositions, methods and kits to control bleeding through the use of an internal occluder based on polymeric solutions, including use of reverse thermosensitive polymers in nephron-sparing surgeries, which produces a completely bloodless surgical field, allowing speedy resection. In certain embodiments, after a certain amount of time, the flow gradually resumes, with no apparent adverse consequences to the kidney. In certain embodiments, return of blood flow may be accelerated by cooling the kidney. The compositions, methods and kits for perfusive organ hemostasis can also be used to simplify or to enable other organ surgeries or interventional procedures, including liver surgery, prostate surgery, brain surgery, surgery of the uterus, spleen surgery and any surgery on any highly vascularized organs.

An exemplary embodiment of the present invention provides a three-dimensional virtual liver surgery planning system including: a digital imaging and communications in medicine (DICOM) receiving module which receives an abdomen computer tomography (CT) volume data set from a picture archiving and communication system (PACS) server; a DICOM loading and noise removing module which loads the received abdomen CT volume data set and remove noises; a standard liver volume estimation module which estimates a standard liver volume (SLV) from the denoised abdomen CT volume data set; a liver extraction module which extracts a three-dimensional liver region; a vessel extraction module which extracts a three-dimensional vessel region including a portal vein, a hepatic artery, a hepatic vein, and an inferior vena cava (IVC); a tumor extraction module which extracts a three-dimensional tumor region; a liver segmentation module which divides the extracted three-dimensional liver region into several segments using landmarks which are selected by a user or a segmentation sphere; and a liver surgery planning module which makes a three-dimensional liver surgery plan using a resection surface, a liver segments, or the segmentation sphere.

The invention discloses a blood occlusion device for a hepatic operation. The device comprises a tube body capable of being planted into a blood vessel. A displacement prevention device is arranged on the outer surface of one end of the tube body. A cavity is arranged inside the tube body. A blood occlusion device body is arranged inside the cavity. The displacement prevention device comprises an expander. The expander comprises a plurality of step protrusions evenly arranged on the outer surface of one end of the tube body. The step protrusions are in a wedge shape. An adjusting groove is formed in the surface, matched with the outer surface of the tube body, of each step protrusion. A groove is formed in the position, matched with each adjusting groove, of the tube body. According to the technical scheme, the displacement prevention device and the blood occlusion device are indispensable; if the displacement prevention device is omitted, the fixed position cannot be ensured, and the operation progress is affected; if the blood occlusion device is omitted, the predetermined effect cannot be achieved. The displacement prevention device and the blood occlusion device are operated in the operation process, so that the operation time is greatly shortened, and the survival probability of a patient is increased.

Provided is an immersion-type self-adaptive pose virtual surgery training platform, comprising four parts of an upper display component, a middle console component, a lower support component and a side support component, and the like. The upper display component, which is designed according to ergonomics, fits a human facial structure and is adapted to human brains with different sizes by adjusting the size of the observation center space via a button, so that the human brains fit well with the platform and the sense of immersion in enhanced. The pose can be adjusted in the self-adaptive way, so that the surgery operation training can be conducted with the appropriate pose, thereby improving the degree of comfort and reducing the fatigue. The whole surgery training process is observed via an external 3D display of the upper display component, so as to evaluate the training effect. The platform of the invention may be used for simulating the operation process of various surgeries, such as brain surgeries, liver surgeries, kidney surgeries, breast surgeries and the like, enables intern doctors or medical college students to conduct the surgery training in the repeated, damage-free and convenient manner, and solves the problems of long training period, low efficiency, high cost, lack of training objects which may occur during traditional surgeon training.

The invention relates to the technical field of medical appliances, and provides a laparoscopic separable primary porta hepatis blocker. The block consists of a primary porta hepatis blocking clamp and a blocking clamp controller, wherein the primary porta hepatis blocking clamp consists of a pair of clamp bodies (1), a body connecting shaft (2) and a spring (3), the pair of the clamp bodies are crossly connected through the body connecting shaft, front arms (1.1) of the clamp bodies are bent like an arc shape, and rear arms (1.2) on the tails of the clamp bodies are provided with latches (1.3); the blocking clamp controller consists of a control lever and a control lever shell (4), and the control lever shell is of an L shape; and the control lever consists of a control handle (5), a first link rod (6), a second link rod (7) and a fixed shaft (8), the control handle (5) is of an L shape, and a lock hole (7.1) for connecting the latches (1.3) on the rear arms of the clamp bodies is formed on the opposite side of the second link rod (7). The laparoscopic separable primary porta hepatis blocker is convenient to use, and solves the problem of blocking blood vessel bleeding of the primary porta hepatis in a laparoscopic liver surgery.

The invention provides a liver spreader of a single-hole laparoscope . The liver spreader comprises an operation rod, a plurality of blades connected with one end of the operation rod, an opening andclosing control assembly and a handle, the opening and closing control assembly and the handle are arranged at the other end of the operation rod, and the operation rod is internally provided with a bracket, a blade push-pull rod and a piston assembly; at most one blade is fixedly connected with the bracket, the other blades are movably connected with the bracket and hinged to push-pull sheets forpushing and pulling the corresponding blades to be opened or reset, one end of the blade push-pull rod is movably connected with all the push-pull sheets, and the other end of the blade push-pull rodis fixedly connected with the opening and closing control assembly; the piston assembly comprises two pistons which move synchronously in opposite directions; each blade comprises a plurality of joint beads connected in series through two steel wires, the two steel wires are fixedly connected with the first piston and the second piston respectively, and one of the two pistons is connected to thehandle. By means of the liver spreader of the single-hole laparoscope, exposure of a surgical field of liver surgery can be enlarged, mutual interference with other surgical instruments is avoided, the convenience degree of surgical operation is increased, and the surgical time is greatly shortened.

A method for surgical resection planning of a mass is disclosed. The method comprises the steps of, modelling the mass based on a plurality of physical dimensions, determining a plurality of safety margins around a plurality of features within the mass, simulating a resection surface on the mass comprising a plurality of triangles, optimizing local area and position of a first of the plurality of triangles on the resection surface based on a triangle-based algorithm, updating the simulation of the resection surface, and repeating the steps of optimizing and updating for each of the plurality of triangles on the resection surface.

The invention discloses an inferior vena cava root vascular anatomical dissecting forceps for liver surgery. The dissecting forceps comprises a forceps body, two forceps handles and a forceps head, wherein the forceps body is a cylinder; the inside of the cylinder is a cavity structure; and the two forceps handles are connected to the rear end of the forceps body and are symmetrically distributedabout the forceps body. The dissecting forceps drives a pull rod to rotate and stretch by a driving structure so as to open and close the forceps head and rotate the forceps head, and to adjust the angle of the forceps head. During inferior vena cava root vascular dissection, a surgeon can operate without twisting his / her wrist, improves operation precision, and avoids a danger caused by twistingthe wrist. The inferior vena cava root vascular anatomical dissecting forceps is convenient to use.

The invention provides an operating forceps for liver surgery, which relates to the technical field of medical equipment. The operating forceps for liver surgery comprises a first forceps handle, a second forceps handle, a first connecting tube and a second connecting tube. The first forceps handle includes a first forceps arm and a first forceps head, wherein a suction interface and a plurality of suction holes are arranged on the first forceps head. A first channel connecting the suction interface and the plurality of suction holes is arranged on the first forceps head, and the first connecting tube is respectively connected with the suction interface and a suction device; the second forceps handle includes a second forceps arm and a second forceps head, wherein a saline interface and aplurality of spray holes are arranged on the second forceps head. A second channel connecting the suction interface and the plurality of suction holes is arranged on the second forceps handle, and thesecond connecting tube is connected with the saline interface and an infusion device respectively. The operating forceps for liver surgery solves the technical problems of traditional techniques in the operation of liver tissue cleanup, namely, blood vessels are easy to be cut and can't be clearly and safely exposed to the intrahepatic duct, which can affect the effect of operation.

The present invention provides a medical Implant (100). The medical Implant (100) comprises: a microbial cellulose tube (1) comprising a wall (2) having an inner surface (3) and an outer surface (4),wherein the wall comprises several layers (5, 6, 7) of microbial cellulose, the layers are concentric or substantially concentric to a longitudinal axis (L) of the tube; and a stent (9) which placed inside of the microbial cellulose tube (1), wherein an outer surface (10) of the stent contacts the inner surface (3) of the microbial cellulose tube (1), and method for producing such implant. The implant can be covered with newly created bile duct epithelium, thereby creating a new bile duct from body cells. The implant can be removed after completion of creation of the new bile duct. So, the implant as suitable as a temporary implant. The implant can be used for surgery, such as surgery of gall bladder, bile duct and / or liver, e.g. gall bladder removal, hepatobiliary malignancy surgery or liver transplantation. The implant can particularly be used for repairing or regeneration of bile duct. Further fields of use are the use as esophagus implant or urether implant.

The invention provides a system for evaluating the risk of complications after hepatic resection of a subject before an operation, and the system comprises a data collection module which is used for obtaining the Child-pugh level of the subject, the condition that whether internal medicine diseases need to be treated by drugs exist, the number of liver segments to be resected, the condition that whether visceral organ invasion exists in the subject or not, and the preoperative hospitalization time of the subject; and the module is used for calculating the complication risk of the subject after the hepatic resection and is used for calculating the information acquired in the data acquisition module so as to calculate the complication risk probability (P) of the subject after the hepatic resection. The system has good reliability, the preoperative prediction of the occurrence rate of the liver surgical complications has good consistency with the actual situation, and the system can be used for evaluating the occurrence risk of the liver surgical complications before the operation.

The invention belongs to the field of medical appliances and relates to an apparatus used for suture pressing during deep knotting in liver surgery laparotomy. The apparatus is a blunt apparatus with one end similar to a fingerstall (which can be fastened at the tail finger joint of the index finger) and a U-shaped opening in the top end; and the apparatus is configured with different fingerstall types and connecting rods of different lengths. In order to solve the problem of inconvenient knotting operation for relatively deep parts such as the right posterior lobe or the caudate lobe of the liver in existing liver surgery operation, the invention provides the deep suture pressing apparatus. The deep suture pressing apparatus is characterized in that a U-shaped suture pressing apparatus is arranged at the head end, so that no sliding is ensured in suture pressing during knotting and a suture knot is firm; the head end is round and blunt, so that the tissues are not injured during operation; and the different fingerstall types and the connecting rods of the different lengths are configured, so that operators can conveniently select the proper types according to self conditions, wearing is convenient, and the problem of deep knotting in the liver surgery is exactly solved. The suture pressing apparatus is easy to process and manufacture, low in cost and high in practicality, and has a wide market prospect.

The invention discloses a surgical pad which is composed of a closed cavity and a strip-shaped liquid delivery pipe which are made from medical rubber and other flexible materials and meet surgery needs. According to the surgical pad disclosed by the invention, the problem troubling the surgery industry and surgeons for a long time in liver surgery that exposure of the operative filed and the operative region is difficultly sufficiently shown is solved. A surgeon can inject normal saline into the one-layer or multi-layer closed cavity by virtue of the strip-shaped liquid delivery pipe according to the surgery needs, so that the specified shape is shown in the closed cavity, the strip-shaped liquid delivery pipe is knotted and stuffed below the liver, so that the liver can be padded, and the needed exposure of the operative field and the operative region is obtained. Since a surgery nurse has the surgical pad made of rubber, risk of retained gauze existing in the surgery while padding the liver is avoided. The surgical pad disclosed by the invention can be applied to the liver surgery and other similar surgical operations. The surgical pad disclosed by the invention is simple in structure and easy to manufacture and operate.

The invention relates to the technical field of liver surgery and particularly to a hepatic portal blocking band which is detachable, has a timing function and does not need blocking pincers. The blocking band comprises a blocking band body; a fixing male piece and a fixing female piece are arranged at the head end and the tail end of the blocking band body respectively; a plurality of protrudingclamps are integrally formed on the fixing male piece; a plurality of inserting holes are formed in the fixing female piece; the protruding clamps can extend into the inserting holes; and the head endand the tail end of the blocking band body are hot-melted into welding ends. According to the hepatic portal blocking band which is detachable, has a timing function and does not need blocking pincers, the fixing male piece and the fixing female piece are arranged to be striking red, so that a surgeon is reminded to pay attention to aligning and embedding of the ends of the blocking band body, and the surgeon does not need to spend time in finding the two ends of the hepatic portal blocking band and then placing blocking pincers. The two ends of the blocking band are closed, so that an exudate cannot enter the tube during an operation, and the exudate in a conventional blocking band tube can be prevented from being thrown into eyes of the surgeon.

The invention discloses a hepatic portal occlusion device with remote control. The hepatic portal occlusion device comprises an upper shell and a lower shell, wherein one side of the upper shell and one side of the lower shell are movably connected together by a hinge, and the other opposite sides of the upper shell and the lower shell are clamped together in an openable-closable manner by a fastener; the upper shell and the lower shell enclose into a hepatic portal occlusion working cavity; the hepatic portal occlusion working cavity is internally provided with a miniature speed-reducing motor, a main controller, a radio-frequency receiving module and a battery module; the output end of the radio-frequency receiving module is connected to the input end of the main controller, and the control-signal output end of the main controller is connected to the driving-signal input end of the miniature speed-reducing motor; an output shaft of the miniature speed-reducing motor is connected witha gear, an occlusion belt is meshed on the gear, and one end of the occlusion belt is fixed at the outer part of the hepatic portal occlusion working cavity. The hepatic portal occlusion device withremote control disclosed by the invention has the beneficial effects that the occlusion belt can be loosened or tightened by remotely controlling the forward and reverse rotation of the miniature speed-reducing motor, so that occlusion and dredge of blood flow into the liver under a laparoscope are realized, the operation is simple and the difficulty and the risk of hepatic portal occlusion in theliver operation are greatly reduced.

The invention discloses a device for generating a surgical cutting plane of the liver. The device comprises: a model generation module, which is used for generating a three-dimensional reconstruction model according to an image segmentation result; a liver segment dividing module, which is used for dividing the liver segment according to the three-dimensional reconstruction model; The surface generation module is used to judge whether each liver segment contains lesions; determine the minimum blood supply area R that contains the lesions S,1 , the minimum blood return area R S,2 and the resection area R T,1 ; based on the minimum blood supply area R S,1 , the minimum blood return area R S,2 and the resection area R T,1 Generate cut planes for liver surgery. The technical scheme of the present invention can help doctors to better plan the operation and preserve more healthy liver tissue.

The present invention provides of compositions of matter comprising a CSF-1 fusion protein and methods of using the same in enhancing regeneration or restoring function of an injured liver. The compositions of matter are useful in the treatment of hepatic disorders, for example, in the prevention and / or treatment of liver disease and to improve outcomes following liver surgery.

Disclosed is a method for establishing a noninvasive evaluation model for liver surgical treatment risks. The method comprises collection of clinical data before surgery, measurement of the portal vein pressure during surgery and establishment of a portal vein pressure prediction equation. The establishment of the liver surgical treatment risk noninvasive evaluation model includes that when the portal vein pressure is smaller than 12 cm H2O, the tolerant resection volume is 40% to 60% of the liver total volume; when the portal vein pressure is between 12 cm and 19 cm H2O, the tolerant resection volume is 30% to 40% of the liver total volume; when the portal vein pressure ranges from 19 cm to 23 cm H2O, the tolerant resection volume is 20% to 30% of the liver total volume; and when the portal vein pressure is larger than 23 cm H2O, the tolerant resection volume is smaller than 20% of the liver total volume. According to the method for establishing the noninvasive evaluation model for liver surgical treatment risks, utilized clinical indicators before surgery are routine inspection items and are noninvasive. The accuracy rate of the portal vein pressure prediction equation is more than 75%, and the deviation is within 2 cm water columns.

The invention provides a method for automatically generating a liver 3D (three-dimensional) image and accurately positioning a liver vascular domination region. The method comprises the following processes: acquiring a liver three-dimensional CT (computed tomography)-enhanced image; positioning and segmenting the liver; extracting liver blood vessels and analyzing the structure of the liver; and analyzing the vascular domination region. In the method, through the topology partitioning, the volume size of the drainage region of each venous blood vessel can be obtained so as to facilitate a surgeon to perform simulation and prediction before a liver surgery, and simultaneously facilitate research and understanding of positions of blood vessels in the liver region for scientific researchers.

The invention relates to the technical field of medical devices, and provides a separable laparoscopic hepatic vein blocker. The blocker comprises hepatic vein blocking forceps and a blocking forceps operator, wherein the hepatic vein blocking forceps consist of a pair of forceps clip limbs (1), a limb connecting shaft (2) and a spring (3), and the pair of forceps clip limbs are connected in a crossing shape through the limb connecting shaft; a front arm (1.1) of each forceps clip limb is shaped as a bent hook, and a rear arm (1.2) of each forceps clip limb is provided with a latch (1.3); theblocking forceps operator consists of a control lever and a control lever shell (4); a pair of chutes (4.2) are formed on the control lever shell; the control lever consists of a control handle (5), a first link lever (6), a second link lever (7) and a stationary shaft (8); and a lockhole (7.1) matched with the latch (1.3) on the rear arm of each forceps clip limb is formed on the opposite side of the front end of the second link lever and used for being connected with the hepatic vein blocking forceps. The separable laparoscopic hepatic vein blocker is simple in structure and convenient in use, and solves the difficult problem of blocking hepatic vein blood flow of the liver in a laparoscopic liver surgery.

A medical implant (100), comprising: - a microbial cellulose tube (1) comprising a wall (2) having an inner surface (3) and an outer surface (4), wherein the The wall comprises a plurality of layers (5, 6, 7) made of microbial cellulose, wherein the layers are coaxial or approximately coaxial with the longitudinal axis (L) of the tube, - a bracket (9), which arranges In a microbial cellulose tube (1), wherein the outer surface (10) of the scaffold is in contact with the inner surface (3) of the microbial cellulose tube (1); and a method for manufacturing such an implant. The implant may be covered by newly generated biliary epithelium, thereby forming a new bile duct from somatic cells. The implant may be removed after formation of the new bile duct is complete. Therefore, the implant is suitable as a temporary implant. The implant may be used in surgical procedures such as gallbladder surgery, bile duct surgery and / or liver surgery such as cholecystectomy, surgery for hepatobiliary malignancies or liver transplantation. The implant can be used in particular for the repair or regeneration of bile ducts. A further field of application is the use as an esophageal or urethral implant.

The invention discloses a method for automatically dividing a liver area in a multi-detector spiral CT image which helps a user to more accurately pick up the liver area in the sequence of the multi-detector spiral CT image and mark a borderline for the user to carry out further analysis and treatment on the liver area by an improved Fast Marching method and being combined with the priori knowledge of a celom location, a liver anatomical location and a liver gray characteristic. The invention realizes to intelligently assist the user to pick up the liver area from the sequence of the multi-detector spiral CT image only needing to appoint two pieces of the beginning and the tail pictures of the sub-sequence of the multi-detector spiral CT image comprising the liver without needing to mark the original profile by hand and can effectively distinguish the liver from the surrounding organs with approximate gray values to obtain an accurate liver profile, thus ensuring the user to fast obtain the liver profile and carry out further analysis and treatment. The method for automatically dividing the liver area in the multi-detector spiral CT image of the invention is suitable for assistingto decide the operation scheme of the liver surgery.

The invention discloses a blood occlusion device for a hepatic operation. The device comprises a tube body capable of being planted into a blood vessel. A displacement prevention device is arranged on the outer surface of one end of the tube body. A cavity is arranged inside the tube body. A blood occlusion device body is arranged inside the cavity. The displacement prevention device comprises an expander. The expander comprises a plurality of step protrusions evenly arranged on the outer surface of one end of the tube body. The step protrusions are in a wedge shape. An adjusting groove is formed in the surface, matched with the outer surface of the tube body, of each step protrusion. A groove is formed in the position, matched with each adjusting groove, of the tube body. According to the technical scheme, the displacement prevention device and the blood occlusion device are indispensable; if the displacement prevention device is omitted, the fixed position cannot be ensured, and the operation progress is affected; if the blood occlusion device is omitted, the predetermined effect cannot be achieved. The displacement prevention device and the blood occlusion device are operated in the operation process, so that the operation time is greatly shortened, and the survival probability of a patient is increased.

The invention relates to the field of biological materials, in particular to a collagen microfiber hemostatic material, a preparation method and a use method thereof. The solid collagen material undergoes high-speed shearing to obtain collagen microfibers. After dispersing the collagen microfibers in the water phase, the procoagulant active ingredients are modified on the surface of the collagen microfibers through linking molecules. Microfiber hemostatic material. Collagen microfiber materials can be easily and efficiently prepared by high-speed shearing, and the biological activity of collagen materials can be kept as much as possible; the length of microfibers ranges from 10um to 1000um, which has high dispersion and is conducive to spraying treatment. Linker molecules can efficiently and quantitatively load procoagulant active ingredients on the surface of collagen microfibrils to enhance their hemostatic effect. The collagen microfiber hemostatic material prepared by the present invention is used for hemostasis on oozing wounds by spraying, such as hemostasis during brain surgery or liver surgery, and can achieve the effect of non-contact fixed-point hemostasis.

The invention relates to the technical field of liver operation tools, in particular to a liver section blood flow blocking device which comprises a fixing ring, and an upper limiting sleeve and a lower limiting sleeve which are used for penetrating through a latex tube are integrally formed at the top and the bottom of the inner wall of the fixing ring respectively. A first through groove and a second through groove are formed in the center of the bottom of the upper limiting sleeve and the center of the top of the lower limiting sleeve correspondingly, a closed pipeline is fixedly connected to the center of the top of the fixing ring, a movable pipeline is slidably connected into the closed pipeline in the vertical direction, and an air inlet is formed in the center of the top of the movable pipeline. A sliding rod is slidably connected into the movable pipeline in the vertical direction, and the bottom of the sliding rod penetrates through the bottom of the movable pipeline and is fixedly connected with an extrusion head. According to the latex tube fixing device, gas can be inflated into the closed pipeline through the inflator pump to increase the pressure in the closed pipeline, then the purpose of pushing the movable pipeline is achieved, and the traditional working mode that a latex tube is fixed by screwing a screwdriver or using operating forceps is replaced.

A method for automatic registration of landmarks in 3D and 2D images of an organ comprises: using a first set of coordinates of identified first, second and third landmarks of the organ, derived froma 3D surface representation of the organ, and a second set of coordinates of the landmarks, derived from 2D laparoscopic images of the organ, to register the three landmarks as identified in the 3D surface representation with the three landmarks as identified in the 2D images. The third landmark comprises a plurality of points defining a path between two points characterizing the first and secondlandmarks The identification of the first, second and third landmarks in the 3D representation and the 2D images, the derivation of the first and second sets of coordinates, and the registration, based on the derived first and second sets of coordinates, are performed automatically.