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184 results about "Portal vein" patented technology

The portal vein or hepatic portal vein is a blood vessel that carries blood from the gastrointestinal tract, gallbladder, pancreas and spleen to the liver. This blood contains nutrients and toxins extracted from digested contents. Approximately 75% of total liver blood flow is through the portal vein, with the remainder coming from the hepatic artery proper. The blood leaves the liver to the heart in the hepatic veins.

Portal design for stent for treating bifurcated vessels

A stent pattern includes an improved portal region for repairing a main vessel and a side branch vessel forming a bifurcation. More particularly, the stent has rings aligned along a common longitudinal axis that are connected by links, where the stent has a proximal section, a distal section, and a central section (portal region). The number of rings and the expanded diameter of the sections are varied to create a “trap door” capable of expanding to a slightly larger diameter than the proximal section and the distal section of the stent. The configuration of the stent pattern of the portal region prevents the occurrence of portal overlap of immediately adjacent rings into the portal region during stent deployment. The stent is implanted at a bifurcation so that the proximal section and the distal section are in the main vessel, and the central section contacts at least a portion of the opening to the side branch vessel. A second stent can be implanted in the side branch vessel and abut the expanded central section to provide full coverage of the bifurcated area in the main vessel and the side branch vessel.
Owner:ABBOTT CARDIOVASCULAR

Hepatic portal vein tree modeling method and system thereof

The invention discloses a hepatic vein vascular tree modeling method and a system thereof. The method comprises the following steps: using a liver model to obtain a liver image, and utilizing the multi-scale filtration method to strengthen a blood vessel; cutting a hepatic vein; extracting a central line of the hepatic vein; detecting and removing a link in the central line; and utilizing OSG / VTK to rebuild the hepatic vein vascular tree after pruning. The system comprises an image acquisition module, a blood vessel strengthening module, a blood vessel cutting module, a vascular tree central line extracting module and a vascular tree rebuilding module. The invention improves similarity functions in the filtering process, analyzes the characteristics of the ring and adopts corresponding unlinking methods for different links; and utilizes the relation of radius of blood vessel and the branch length when pruning. The invention effectively enhances the hepatic vein, improves the contrast between the blood vessel and liver parenchyma, and can extract more than five class branches, effectively unlink and prune the central line of the hepatic vein, rebuild the hepatic vein vascular tree and directly display the branches of the heptatic vein.
Owner:HUAZHONG UNIV OF SCI & TECH

Covered endoprosthesis and delivery system

InactiveUS7056336B2Easily and accurately placed within intrahepatic tractEasy to manufactureStentsBlood vesselsVeinStent grafting
The present invention is an improved endovascular device particularly useful for use in transjugular intrahepatic portosystemic shunt (TIPS) procedures. The device employs a two-part stent-graft construction that provides a low permeability membrane to line the shunt and an uncovered stent portion designed to reside in the portal vein. The device provides numerous benefits over previous stents and stent-grafts used in TIPS procedures, including being more compact to deliver, being easier to accurately deploy, a controlled compacted surface with tucked apices, an improved stent winding pattern, and being more flexible in delivery and use.
Owner:WL GORE & ASSOC INC

Combined parasympathetic stimulation and drug therapy

InactiveUS20080125843A1Enhancing and sustaining efficacyImprove efficiencyHeart defibrillatorsMedical devicesNervous systemMyelitis
A method is provided for treating a subject, including applying a current to a site of the subject selected from the list consisting of: a vagus nerve of the subject, an epicardial fat pad of the subject, a pulmonary vein of the subject, a carotid artery of the subject, a carotid sinus of the subject, a vena cava vein of the subject, and an internal jugular vein of the subject. The method also includes configuring the current so as to treat a condition of the subject selected from the list consisting of: an autoimmune disease, an autoimmune inflammatory disease, multiple sclerosis, encephalitis, myelitis, immune-mediated neuropathy, myositis, dermatomyositis, polymyositis, inclusion body myositis, inflammatory demyelinating polyradiculoneuropathy, Guillain Barre syndrome, myasthenia gravis, inflammation of the nervous system, inflammatory bowel disease, Crohn's disease, ulcerative colitis, SLE (systemic lupus erythematosus), rheumatoid arthritis, vasculitis, polyarteritis nodosa, Sjogren syndrome, mixed connective tissue disease, glomerulonephritis, thyroid autoimmune disease, sepsis, meningitis, a bacterial infection, a viral infection, a fungal infection, sarcoidosis, hepatitis, and portal vein hypertension.
Owner:MEDTRONIC INC

High-simulation laparoscopic surgery simulated training device

ActiveCN103886797APerceived realityShorten learning curveEducational modelsAbdomen skinPortal vein
A high-simulation laparoscopic surgery simulated training device comprises a simulated human abdomen unit, an animal liver and a simulated canal system, wherein the simulated human abdomen unit is used for simulating the human abdomen skin through silica gel and composed of anterior abdominal wall skin and back skin which can be separated from each other, the anterior abdominal wall skin and the back skin are connected through sealing buckles, and thus the seal performance of the whole simulated human abdomen is guaranteed; the animal liver is arranged in the simulated human abdomen unit; the simulated canal system is arranged in the simulated human abdomen unit and connected with the animal liver. According to the high-simulation laparoscopic surgery simulated training device, the abdominal skin is simulated through sealing silica gel, inflation is performed through a poking clip to form the pneumoperitoneum, the human blood circulation in the physiological state is achieved through a pumping set, the real animal liver is anastomosed with the postcava, the portal vein, the hepatic artery and the biliary tract of a human simulator training system through the postcava, the portal vein, the hepatic artery and the biliary tract, and thus various simple or complex laparoscopic surgery training items can be carried out.
Owner:XIAN MAGNETIC MEDICAL TECH CO LTD

Portable preserving device for liver external perfusing

The invention relates to a portable liver extracorporal charging preservation apparatus for liver transplantation comprising a constant temperature water bath tank for liver storage, an oxygenator, a hepatic artery charging circulation loop and a portal vein charging circulation loop, and an intelligent control device for controlling bath tank temperature and flow capacity of charging circulation loop. The liver dual perfusion model created by the invention can carry out oxygen cycle charging to the exsomatized liver at normothermia.
Owner:鞠烽炽 +2

Portal design for stent for treating bifurcated vessels

A stent pattern includes an improved portal region for repairing a main vessel and a side branch vessel forming a bifurcation. More particularly, the stent has rings aligned along a common longitudinal axis that are connected by links, where the stent has a proximal section, a distal section, and a central section (portal region). The number of rings and the expanded diameter of the sections are varied to create a “trap door” capable of expanding to a slightly larger diameter than the proximal section and the distal section of the stent. The configuration of the stent pattern of the portal region prevents the occurrence of portal overlap of immediately adjacent rings into the portal region during stent deployment. The stent is implanted at a bifurcation so that the proximal section and the distal section are in the main vessel, and the central section contacts at least a portion of the opening to the side branch vessel. A second stent can be implanted in the side branch vessel and abut the expanded central section to provide full coverage of the bifurcated area in the main vessel and the side branch vessel.
Owner:ABBOTT CARDIOVASCULAR

Isolated liver perfusion system and method

ActiveCN105660604AGuaranteed vital activityAlleviate reperfusion injuryDead animal preservationTemperature controlVein
The invention discloses an isolated liver perfusion system and method. The system comprises a perfusate temperature control tank, an isolated liver preservation tank, a portal vein perfusion path, a hepatic artery perfusion path, a perfusate backflow path and a bile collector. The portal vein perfusion path is used for conveying perfusate to the portal vein of an isolated liver, the hepatic artery perfusion path is used for conveying perfusate to the hepatic artery of the isolated liver, the perfusate backflow path is used for recycling perfusate flowing out of the isolated liver into the perfusate temperature control tank, and the bile collector is connected with the isolated liver preservation tank and used for collecting bile. The isolated liver is perfused from the portal vein and the hepatic artery through the two paths respectively, the system and method are applicable to damage protection in the isolated liver preservation process, the reperfusion injury of the liver can be significantly relieved, and reliability, stability and repeatability are high. The system and method can effectively store the isolated liver at low temperature, mild hypothermia and normal temperature, and the limitation that the isolated liver needs to be stored at low temperature and the requirement for marginal donor liver preservation cannot be met in the prior art is changed.
Owner:杭州莱普晟医疗科技有限公司

Transcaval mesenteric venous anastomosis and access system

InactiveUS20100106171A1Safe and effective treatment for portal hypertensionSafe and repeated accessDiagnosticsSurgical needlesPortal venous systemPortal vein
Disclosed is a system for creating an anastomosis between the inferior vena cava (IVC) and the mesenteric portal vein. The system includes an anastomosis device and a catheter. The anastomosis device brings the IVC and the portal vein into apposition. The resulting anastomosis enables treatment for portal hypertension as well as provides repeated and easy access to the portal system for direct delivery of therapeutic agents to portal organs. The anastomosis device has a proximal flange part, a distal flange part, a flow lumen between them. The proximal and distal flange parts include a plurality of radial struts. A valve part is disposed on one or both of the proximal and distal flange parts. The anastomosis device is made of a memory shape material. The catheter contains a collapsed anastomosis device for insertion and has one or more RF antennas to make the catheter visible under MRI guidance.
Owner:THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE

Electrosurgical resection instrument

An electrosurgical resection instrument for applying to biological tissue radiofrequency electromagnetic energy has a protective hull comprising a shaped piece of dielectric material mounted to cover an underside of an instrument tip of the instrument. The protective hull acts as a shield to protect tissue that may lie under the instrument tip from damage during treatment. The instrument may be particularly useful in procedures performed in a gastrointestinal tract, where bowel perforation is a concern, or in the pancreas, where damage to the portal vein or the pancreatic duct may occur when a tumour or other abnormality is being resected, dissected or removed.
Owner:CREO MEDICAL LTD

Realization method of computer-assisted liver transplantation operation planning system

InactiveCN102938027AStable and efficient shape priorsEffective adaptabilityImage enhancementImage analysisVeinLiver parenchyma
The invention relates to a realization method of a computer-assisted liver transplantation operation planning system, comprising the following steps: step 1, establishing a normal person liver shape library; step 2, for the liver to be operated, modeling the initial partition result of the liver area by using a method based on sparse representation, and eliminating disturbance of singular point and noise data, so as to obtain a prior shape having a liver area with patient adaptability; steps 3, precisely partitioning the liver by utilizing the prior shape, and simultaneously separating out liver parenchyma, portal vein, liver vein and tumour; step 4, dividing the liver into eight liver segments independent in functions by utilizing the liver vein partition result, and calculating the volume of each liver segment and the tumour; and step 5, carrying out 3D visualization on the partitioning and segmenting result. Compared with the prior art, the realization method has the advantages of high precision and robustness, convenience in realization and capability of treating complicated liver shapes.
Owner:HEBEI UNIVERSITY

High-simulation interventional operation trainer

ActiveCN103886798APerceived realityShorten the surgical learning curveEducational modelsHuman bodyPortal vein
A high-simulation interventional operation trainer comprises a human simulator unit with an abdominal cavity, animal organs, auxiliary canals, a blood collection pool and a pumping set unit, wherein the animal organs are arranged in the abdominal cavity of the human simulator unit, the auxiliary canals are connected with the animal organs, the blood collection pool is communicated with the auxiliary canals to supply perfusate to the auxiliary canals and recover perfusate, and the pumping set unit is arranged between the blood collection pool and the auxiliary canals and provides perfusate circulation driving power. According to the high-simulation interventional operation trainer, transparent silicone hoses which can be punctured repeatedly without leakage are used for simulating the main blood vessels in the human body, colored liquid can be pumped into the artificial canals through the pumping set to simulate blood so as to construct blood circulation, the real animal organs such as a liver, a spleen and kidneys are in fit with the inferior vena cava, the portal vein, the hepatic artery, the biliary tract and other blood vessels of a human simulator training system through the inferior vena cava, the portal vein, the hepatic artery and the biliary tract, and thus the interventional operation simulation training system highly simulating the anatomical structure and the physiological status of the human body is constructed.
Owner:XIAN MAGNETIC MEDICAL TECH CO LTD

Segmentation method of viscera and internal blood vessels thereof in surgical planning system

The invention relates to a segmentation method of medical images, and specifically relates to a segmentation method of viscera and internal blood vessels thereof in a surgical planning system. The method designs a segmentation method of images of liver parenchyma, portal veins and hepatic veins based on minimal supervised classification of the three-dimensional CT images of the viscera and internal tubular tissues thereof. The method applies methods of statistics and spatial information, introduces high credible points, and obtains segmentation results based on arrival time of fast march of grey level. The method assumes that spatially adjacent points belong to a same organ, and performs segmentation calculation on the images by using a classification algorithm based on the above assumption, wherein the segmentation calculation comprises the steps of: acquiring estimated values of parameters of a Gaussian mixture distribution model; selecting the high credible points; and calculating the mean value of the grey level of the images and calculating the arrival time by using a fast marching algorithm to obtain arrival time images of three tissue classifications. According to the invention, good robustness and good anti-noise interference capability are obtained, accumulated errors are eliminated effectively, classification accuracy is improved, and great application value in clinical treatment is achieved.
Owner:SUZHOU DIKAIER MEDICAL TECH

Method for isolating and culturing liver primary cells

The invention provides a method for isolating and culturing liver primary cells. The method comprises the following steps: (1) inputting perfusate from hepatic portal vein of a liver; (2) inputting collagenase perfusate; (3) soaking the maturely digested liver in the collagenase perfusate; (4) adding a cleaning solution to stop digestion, filtering, and collecting hepatic cell suspension; and (5) centrifuging, discarding supernatant, resuspending with complete medium, and culturing. The operation of the method provided by the invention is simple, is low in cost and is stable and efficient, and the hepatic cells are high in yield, high in vitality and easy for adherence. The method can be generalized in laboratories, and is a conventional method for scientific research.
Owner:CHINA AGRI UNIV

Transjugular intrahepatic portosystemic shunt device

An apparatus method for establishing a Transjugular Intrahepatic Portosystemic Shunt between the portal vein from a hepatic vein. The apparatus comprises an elongated hollow outer guide; an outer handle having an inner lumen and a first luer lock, the outer handle attached at a proximal end of the outer guide, the outer guide in flow communication with the inner lumen and the first luer lock; an elongated hollow inner needle; and a hub having a second luer lock, the hub attached at a proximal end of the inner needle, the inner needle in flow communication with the second luer lock. The inner needle is slidingly received into the outer guide through the inner lumen. The inner needle rotates within the outer guide by manipulation of the hub; and a distal tip of the inner needle is deployed out of and beyond a distal tip of the outer guide.
Owner:HATCH MEDICAL

Liver segmentation method and system thereof

The invention relates to the field of medical image processing and provides a liver segmentation method and a system thereof. The method comprises the following steps of: segmenting medical image sequences of a liver to obtain segmentation images of the liver and a portal vein; obtaining a center line and a radius of the portal vein; making different marks on different segments of the liver in the center line of the portal vein; segmenting the liver based on marked center line of the portal vein. Therefore, the invention provides the method and the system for individualized liver segmentation and provides good security for clinical surgery.
Owner:SHENZHEN YORATAL DMIT

Pre-stressed rack of intrahepatic portacaval shunt

InactiveCN1748660APlay a decisive roleRelease position is accurateSurgeryBlood vesselsVeinPre stress
The pre-stressed rack of intrahepatic portal vein bypass includes main rack and auxiliary rack connected via Ni-Ti alloy wire in 40-90deg angle, and both the main rack and the auxiliary rack are nets woven with Ni-Ti alloy wires. The main rack has the end far from the auxiliary rack in radial shape, the pre-stressed rack is a coated one and has diameter of 8-10 mm, and the main rack and the auxiliary rack has length of 3-5cm and 1.5cm separately. Under the action of pre-stress, the pre-stressed rack has its main rack, auxiliary rack and í‹hat brimíŒ contact closely with the left branch, the right branch and the lower liver section cavity wall of the portal vein separately. The present invention has structure coincide the anatomical relation of the intrahepatic portal vein and is significant in further perfection of PTPS.
Owner:褚建国

Liver normal temperature perfusion restoration system

The invention discloses a liver normal temperature perfusion restoration system. The system comprises a liver container. The liver container comprises a main body and an upper cover. The main body and the upper cover are fastened tightly. A silica gel flexible net is fixed to the main body of the liver container. The lower end of the main body of the liver container is provided with a blood return channel. The blood return channel is connected to a centrifugal pump by a blood storage tank. The front end of the blood storage tank is provided with a filter film. An outlet end of the centrifugal pump is connected to an oxygenator. The oxygenator is connected to an oxygen control device. A blood pipe of the oxygenator is divided into two paths by a heat exchanger, one path is used for hepatic artery perfusion by a roller pump and the other path is used for direct portal vein perfusion. Liver artery forms a pulsatile blood flow under the action of the roller pump so that physiological liver artery perfusion is simulated and bile duct cell protection is realized in perfusion. The system can keep hepatocyte aerobic metabolism at a normal temperature, realizes short-time restoration treatment on the liver and widens a liver source.
Owner:ZHEJIANG UNIV

Three-dimensionlal virtual liver surgery planning system

InactiveUS20150063668A1Easily extract liverImage enhancementImage analysisData setDigital imaging
An exemplary embodiment of the present invention provides a three-dimensional virtual liver surgery planning system including: a digital imaging and communications in medicine (DICOM) receiving module which receives an abdomen computer tomography (CT) volume data set from a picture archiving and communication system (PACS) server; a DICOM loading and noise removing module which loads the received abdomen CT volume data set and remove noises; a standard liver volume estimation module which estimates a standard liver volume (SLV) from the denoised abdomen CT volume data set; a liver extraction module which extracts a three-dimensional liver region; a vessel extraction module which extracts a three-dimensional vessel region including a portal vein, a hepatic artery, a hepatic vein, and an inferior vena cava (IVC); a tumor extraction module which extracts a three-dimensional tumor region; a liver segmentation module which divides the extracted three-dimensional liver region into several segments using landmarks which are selected by a user or a segmentation sphere; and a liver surgery planning module which makes a three-dimensional liver surgery plan using a resection surface, a liver segments, or the segmentation sphere.
Owner:POSTECH ACAD IND FOUND +1

Noninvasive portal vein hemodynamic parameter measuring method

The invention provides a noninvasive portal vein hemodynamic parameter measuring method which includes the steps of firstly, using a thin-section CT image to build a three-dimensional geometric model of a liver portal vein; secondly, using the finite element analyzing method of hydromechanics calculating software ANSYS to perform meshing on the geometric model and build a three-dimensional mathematic model; thirdly, calculating the hemodynamic parameter of the portal vein in an analog manner to obtain a speed and pressure distribution effect picture. The method is safe, noninvasive, simple to operate, visualized, quantized and high in accuracy, and the effective model is built for scientific researches and clinic services.
Owner:SHANGHAI TONGJI HOSPITAL

Liver perfusion device

The invention discloses a liver perfusion device, which comprises a main machine, an air-oxygen mixer assembly and a monitoring assembly. A consumable assembly is clamped on a worktable of the main machine, and when different livers need to be perfused, only the consumable assembly needs to be replaced, so that convenience is achieved; the main machine is internally provided with a temperature adjusting assembly in pipeline connection with the consumable assembly, thus the temperature of circulating water entering a first lung membrane oxygenator and a second lung membrane oxygenator for heatexchange can be adjusted through the temperature adjusting assembly, and then liver perfusion can be conducted under different temperature conditions according to the actual needs; and in addition, the main machine has different liver perfusion modes, a user can set hepatic artery and portal vein perfusion methods according to the actual needs, the perfusate oxygenation degree is adjusted according to an air-oxygen mixer, different drugs are injected by a micro-injection pump, and the effects of liver long-term preservation, improvement, repair and the like are achieved.
Owner:GUANGDONG DEVOCEAN MEDICAL INSTR CO LTD

Liver image segregation method based on hierarchy vessel tree division

The invention relates to a liver image segregation method based on hierarchy vessel tree division. The method comprises the steps that firstly, a directed tree is utilized to represent a topological structure of a liver portal vein vessel, then according to space distribution and branch average radius information of the liver portal vein vessel in a specific clinical case image, vessel hierarchical parameters are determined and a hierarchical vessel tree is created, a second-level subtree set providing blood for a liver is marked, marked second-level subtrees are divided into eight kinds according to blood supplying areas, the liver is divided into eight hepatic segments through the adoption of the shortest distance algorithm to be analyzed, and clinical interesting information is extracted. According to the method, for liver vessels with multiple branches and complex structures, good hieratical effects can be obtained, blood supplying effects of most second-level branches are considered, and hepatic segment distribution and attribute information obtained through segregation also accord with the Couinaud hepatic segmentation theory.
Owner:TONGJI UNIV

Separable portal vein blocker under laparoscope

InactiveCN102125452AReduce occlusionSolve the problem of blocking the blood flow of the portal vein of the liverWound clampsVeinPortal vein flow
The invention relates to the technical field of medical apparatuses and discloses a separable portal vein blocker under a laparoscope. The separable portal vein blocker consists of a pair of vein blocking pincers and a blocking pincer manipulator. The pair of vein blocking pincers consists of a pair of pincer limbs (1), a limb connecting shaft (2) and a spring (3), wherein the pair of pincer limbs is in cross connection through the limb connecting shaft; front arms (1.1) of the pincer limbs are cambered and bent; and the tail parts of rear arms (1.2) of the pincer limbs are provided with lock catches (1.3). The blocking pincer manipulator consists of an operating rod and an operating rod shell (4), wherein a pair of chutes (4.2) is formed on the two sides of the tail part of the operating rod shell; the operating rod consists of a control handle (5), a first linkage rod (6), a second linkage rod (7) and a fixing shaft (8); and lock holes (7.1) matched with the lock catches (1.3) of the rear arms of the pincer limbs are formed on the opposite faces of the front ends of the two linkage rods, so that the linkage rods are linked with the veining blocking pincers. The separable portal vein blocker has a simple structure, is convenient to use and solves the problem of blocking portal vein bleeding of a liver operation under the laparoscope.
Owner:SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY

Novel acetysalicylic acid formulations

The invention relates to pharmaceutical compositions of acetylsalicylic acid-based microcapsules to selectively inhibit the COX in the portal vein and / or in the liver to reduce the production of thromboxane. Further, the pharmaceutical composition minimizes COX inhibition in the systemic circulation to optimize the inhibition of platelet aggregation. Certain embodiments also address methods of prevention and / or treatment of these diseases, using these oral compositions such as enhancing the safety of antithrombotic treatments. Other embodiments contemplate oral pharmaceutical compositions that combine acetylsalicylic acid with anti-platelet aggregation drugs, without inducing gastric side effects.
Owner:NEW HAVEN PHARMA
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