180 results about "Portal vein" patented technology

A stent pattern includes an improved portal region for repairing a main vessel and a side branch vessel forming a bifurcation. More particularly, the stent has rings aligned along a common longitudinal axis that are connected by links, where the stent has a proximal section, a distal section, and a central section (portal region). The number of rings and the expanded diameter of the sections are varied to create a “trap door” capable of expanding to a slightly larger diameter than the proximal section and the distal section of the stent. The configuration of the stent pattern of the portal region prevents the occurrence of portal overlap of immediately adjacent rings into the portal region during stent deployment. The stent is implanted at a bifurcation so that the proximal section and the distal section are in the main vessel, and the central section contacts at least a portion of the opening to the side branch vessel. A second stent can be implanted in the side branch vessel and abut the expanded central section to provide full coverage of the bifurcated area in the main vessel and the side branch vessel.

The invention discloses a hepatic vein vascular tree modeling method and a system thereof. The method comprises the following steps: using a liver model to obtain a liver image, and utilizing the multi-scale filtration method to strengthen a blood vessel; cutting a hepatic vein; extracting a central line of the hepatic vein; detecting and removing a link in the central line; and utilizing OSG/VTK to rebuild the hepatic vein vascular tree after pruning. The system comprises an image acquisition module, a blood vessel strengthening module, a blood vessel cutting module, a vascular tree central line extracting module and a vascular tree rebuilding module. The invention improves similarity functions in the filtering process, analyzes the characteristics of the ring and adopts corresponding unlinking methods for different links; and utilizes the relation of radius of blood vessel and the branch length when pruning. The invention effectively enhances the hepatic vein, improves the contrast between the blood vessel and liver parenchyma, and can extract more than five class branches, effectively unlink and prune the central line of the hepatic vein, rebuild the hepatic vein vascular tree and directly display the branches of the heptatic vein.

The present invention is an improved endovascular device particularly useful for use in transjugular intrahepatic portosystemic shunt (TIPS) procedures. The device employs a two-part stent-graft construction that provides a low permeability membrane to line the shunt and an uncovered stent portion designed to reside in the portal vein. The device provides numerous benefits over previous stents and stent-grafts used in TIPS procedures, including being more compact to deliver, being easier to accurately deploy, a controlled compacted surface with tucked apices, an improved stent winding pattern, and being more flexible in delivery and use.

A high-simulation laparoscopic surgery simulated training device comprises a simulated human abdomen unit, an animal liver and a simulated canal system, wherein the simulated human abdomen unit is used for simulating the human abdomen skin through silica gel and composed of anterior abdominal wall skin and back skin which can be separated from each other, the anterior abdominal wall skin and the back skin are connected through sealing buckles, and thus the seal performance of the whole simulated human abdomen is guaranteed; the animal liver is arranged in the simulated human abdomen unit; the simulated canal system is arranged in the simulated human abdomen unit and connected with the animal liver. According to the high-simulation laparoscopic surgery simulated training device, the abdominal skin is simulated through sealing silica gel, inflation is performed through a poking clip to form the pneumoperitoneum, the human blood circulation in the physiological state is achieved through a pumping set, the real animal liver is anastomosed with the postcava, the portal vein, the hepatic artery and the biliary tract of a human simulator training system through the postcava, the portal vein, the hepatic artery and the biliary tract, and thus various simple or complex laparoscopic surgery training items can be carried out.

The invention relates to a portable liver extracorporal charging preservation apparatus for liver transplantation comprising a constant temperature water bath tank for liver storage, an oxygenator, a hepatic artery charging circulation loop and a portal vein charging circulation loop, and an intelligent control device for controlling bath tank temperature and flow capacity of charging circulation loop. The liver dual perfusion model created by the invention can carry out oxygen cycle charging to the exsomatized liver at normothermia.

The invention discloses an isolated liver perfusion system and method. The system comprises a perfusate temperature control tank, an isolated liver preservation tank, a portal vein perfusion path, a hepatic artery perfusion path, a perfusate backflow path and a bile collector. The portal vein perfusion path is used for conveying perfusate to the portal vein of an isolated liver, the hepatic artery perfusion path is used for conveying perfusate to the hepatic artery of the isolated liver, the perfusate backflow path is used for recycling perfusate flowing out of the isolated liver into the perfusate temperature control tank, and the bile collector is connected with the isolated liver preservation tank and used for collecting bile. The isolated liver is perfused from the portal vein and the hepatic artery through the two paths respectively, the system and method are applicable to damage protection in the isolated liver preservation process, the reperfusion injury of the liver can be significantly relieved, and reliability, stability and repeatability are high. The system and method can effectively store the isolated liver at low temperature, mild hypothermia and normal temperature, and the limitation that the isolated liver needs to be stored at low temperature and the requirement for marginal donor liver preservation cannot be met in the prior art is changed.

Disclosed is a system for creating an anastomosis between the inferior vena cava (IVC) and the mesenteric portal vein. The system includes an anastomosis device and a catheter. The anastomosis device brings the IVC and the portal vein into apposition. The resulting anastomosis enables treatment for portal hypertension as well as provides repeated and easy access to the portal system for direct delivery of therapeutic agents to portal organs. The anastomosis device has a proximal flange part, a distal flange part, a flow lumen between them. The proximal and distal flange parts include a plurality of radial struts. A valve part is disposed on one or both of the proximal and distal flange parts. The anastomosis device is made of a memory shape material. The catheter contains a collapsed anastomosis device for insertion and has one or more RF antennas to make the catheter visible under MRI guidance.

An electrosurgical resection instrument for applying to biological tissue radiofrequency electromagnetic energy has a protective hull comprising a shaped piece of dielectric material mounted to cover an underside of an instrument tip of the instrument. The protective hull acts as a shield to protect tissue that may lie under the instrument tip from damage during treatment. The instrument may be particularly useful in procedures performed in a gastrointestinal tract, where bowel perforation is a concern, or in the pancreas, where damage to the portal vein or the pancreatic duct may occur when a tumour or other abnormality is being resected, dissected or removed.

The invention relates to a realization method of a computer-assisted liver transplantation operation planning system, comprising the following steps: step 1, establishing a normal person liver shape library; step 2, for the liver to be operated, modeling the initial partition result of the liver area by using a method based on sparse representation, and eliminating disturbance of singular point and noise data, so as to obtain a prior shape having a liver area with patient adaptability; steps 3, precisely partitioning the liver by utilizing the prior shape, and simultaneously separating out liver parenchyma, portal vein, liver vein and tumour; step 4, dividing the liver into eight liver segments independent in functions by utilizing the liver vein partition result, and calculating the volume of each liver segment and the tumour; and step 5, carrying out 3D visualization on the partitioning and segmenting result. Compared with the prior art, the realization method has the advantages of high precision and robustness, convenience in realization and capability of treating complicated liver shapes.

A high-simulation interventional operation trainer comprises a human simulator unit with an abdominal cavity, animal organs, auxiliary canals, a blood collection pool and a pumping set unit, wherein the animal organs are arranged in the abdominal cavity of the human simulator unit, the auxiliary canals are connected with the animal organs, the blood collection pool is communicated with the auxiliary canals to supply perfusate to the auxiliary canals and recover perfusate, and the pumping set unit is arranged between the blood collection pool and the auxiliary canals and provides perfusate circulation driving power. According to the high-simulation interventional operation trainer, transparent silicone hoses which can be punctured repeatedly without leakage are used for simulating the main blood vessels in the human body, colored liquid can be pumped into the artificial canals through the pumping set to simulate blood so as to construct blood circulation, the real animal organs such as a liver, a spleen and kidneys are in fit with the inferior vena cava, the portal vein, the hepatic artery, the biliary tract and other blood vessels of a human simulator training system through the inferior vena cava, the portal vein, the hepatic artery and the biliary tract, and thus the interventional operation simulation training system highly simulating the anatomical structure and the physiological status of the human body is constructed.

The invention relates to a segmentation method of medical images, and specifically relates to a segmentation method of viscera and internal blood vessels thereof in a surgical planning system. The method designs a segmentation method of images of liver parenchyma, portal veins and hepatic veins based on minimal supervised classification of the three-dimensional CT images of the viscera and internal tubular tissues thereof. The method applies methods of statistics and spatial information, introduces high credible points, and obtains segmentation results based on arrival time of fast march of grey level. The method assumes that spatially adjacent points belong to a same organ, and performs segmentation calculation on the images by using a classification algorithm based on the above assumption, wherein the segmentation calculation comprises the steps of: acquiring estimated values of parameters of a Gaussian mixture distribution model; selecting the high credible points; and calculating the mean value of the grey level of the images and calculating the arrival time by using a fast marching algorithm to obtain arrival time images of three tissue classifications. According to the invention, good robustness and good anti-noise interference capability are obtained, accumulated errors are eliminated effectively, classification accuracy is improved, and great application value in clinical treatment is achieved.

An apparatus method for establishing a Transjugular Intrahepatic Portosystemic Shunt between the portal vein from a hepatic vein. The apparatus comprises an elongated hollow outer guide; an outer handle having an inner lumen and a first luer lock, the outer handle attached at a proximal end of the outer guide, the outer guide in flow communication with the inner lumen and the first luer lock; an elongated hollow inner needle; and a hub having a second luer lock, the hub attached at a proximal end of the inner needle, the inner needle in flow communication with the second luer lock. The inner needle is slidingly received into the outer guide through the inner lumen. The inner needle rotates within the outer guide by manipulation of the hub; and a distal tip of the inner needle is deployed out of and beyond a distal tip of the outer guide.

The invention relates to the field of medical image processing and provides a liver segmentation method and a system thereof. The method comprises the following steps of: segmenting medical image sequences of a liver to obtain segmentation images of the liver and a portal vein; obtaining a center line and a radius of the portal vein; making different marks on different segments of the liver in the center line of the portal vein; segmenting the liver based on marked center line of the portal vein. Therefore, the invention provides the method and the system for individualized liver segmentation and provides good security for clinical surgery.

The pre-stressed rack of intrahepatic portal vein bypass includes main rack and auxiliary rack connected via Ni-Ti alloy wire in 40-90deg angle, and both the main rack and the auxiliary rack are nets woven with Ni-Ti alloy wires. The main rack has the end far from the auxiliary rack in radial shape, the pre-stressed rack is a coated one and has diameter of 8-10 mm, and the main rack and the auxiliary rack has length of 3-5cm and 1.5cm separately. Under the action of pre-stress, the pre-stressed rack has its main rack, auxiliary rack and í‹hat brimíŒ contact closely with the left branch, the right branch and the lower liver section cavity wall of the portal vein separately. The present invention has structure coincide the anatomical relation of the intrahepatic portal vein and is significant in further perfection of PTPS.

The invention discloses a liver normal temperature perfusion restoration system. The system comprises a liver container. The liver container comprises a main body and an upper cover. The main body and the upper cover are fastened tightly. A silica gel flexible net is fixed to the main body of the liver container. The lower end of the main body of the liver container is provided with a blood return channel. The blood return channel is connected to a centrifugal pump by a blood storage tank. The front end of the blood storage tank is provided with a filter film. An outlet end of the centrifugal pump is connected to an oxygenator. The oxygenator is connected to an oxygen control device. A blood pipe of the oxygenator is divided into two paths by a heat exchanger, one path is used for hepatic artery perfusion by a roller pump and the other path is used for direct portal vein perfusion. Liver artery forms a pulsatile blood flow under the action of the roller pump so that physiological liver artery perfusion is simulated and bile duct cell protection is realized in perfusion. The system can keep hepatocyte aerobic metabolism at a normal temperature, realizes short-time restoration treatment on the liver and widens a liver source.

An exemplary embodiment of the present invention provides a three-dimensional virtual liver surgery planning system including: a digital imaging and communications in medicine (DICOM) receiving module which receives an abdomen computer tomography (CT) volume data set from a picture archiving and communication system (PACS) server; a DICOM loading and noise removing module which loads the received abdomen CT volume data set and remove noises; a standard liver volume estimation module which estimates a standard liver volume (SLV) from the denoised abdomen CT volume data set; a liver extraction module which extracts a three-dimensional liver region; a vessel extraction module which extracts a three-dimensional vessel region including a portal vein, a hepatic artery, a hepatic vein, and an inferior vena cava (IVC); a tumor extraction module which extracts a three-dimensional tumor region; a liver segmentation module which divides the extracted three-dimensional liver region into several segments using landmarks which are selected by a user or a segmentation sphere; and a liver surgery planning module which makes a three-dimensional liver surgery plan using a resection surface, a liver segments, or the segmentation sphere.

The invention provides a noninvasive portal vein hemodynamic parameter measuring method which includes the steps of firstly, using a thin-section CT image to build a three-dimensional geometric model of a liver portal vein; secondly, using the finite element analyzing method of hydromechanics calculating software ANSYS to perform meshing on the geometric model and build a three-dimensional mathematic model; thirdly, calculating the hemodynamic parameter of the portal vein in an analog manner to obtain a speed and pressure distribution effect picture. The method is safe, noninvasive, simple to operate, visualized, quantized and high in accuracy, and the effective model is built for scientific researches and clinic services.

The invention relates to a liver image segregation method based on hierarchy vessel tree division. The method comprises the steps that firstly, a directed tree is utilized to represent a topological structure of a liver portal vein vessel, then according to space distribution and branch average radius information of the liver portal vein vessel in a specific clinical case image, vessel hierarchical parameters are determined and a hierarchical vessel tree is created, a second-level subtree set providing blood for a liver is marked, marked second-level subtrees are divided into eight kinds according to blood supplying areas, the liver is divided into eight hepatic segments through the adoption of the shortest distance algorithm to be analyzed, and clinical interesting information is extracted. According to the method, for liver vessels with multiple branches and complex structures, good hieratical effects can be obtained, blood supplying effects of most second-level branches are considered, and hepatic segment distribution and attribute information obtained through segregation also accord with the Couinaud hepatic segmentation theory.

Embodiments of the present invention encompass systems and methods for administering intrathoracic pressure and cooling treatments to patients suffering from or at risk of developing heart failure, cardiac arrest, sepsis, shock, acute respiratory distress syndrome, polytrauma, head disease, elevated hepatic or portal vein pressures, bleeding during abdominal, head and neck surgery, or insufficient circulation during open heart surgery.

The invention relates to pharmaceutical compositions of acetylsalicylic acid-based microcapsules to selectively inhibit the COX in the portal vein and/or in the liver to reduce the production of thromboxane. Further, the pharmaceutical composition minimizes COX inhibition in the systemic circulation to optimize the inhibition of platelet aggregation. Certain embodiments also address methods of prevention and/or treatment of these diseases, using these oral compositions such as enhancing the safety of antithrombotic treatments. Other embodiments contemplate oral pharmaceutical compositions that combine acetylsalicylic acid with anti-platelet aggregation drugs, without inducing gastric side effects.

The invention provides a method, a device and an implementation device for detecting a liver occupying infection focus area. The method comprises the following steps: a step of acquiring CT enhanced images of a liver, wherein the CT enhanced images comprise arterial phase images, portal vein phase images and parenchymal phase images; the images for each phase include a plurality frames of image; in the arterial phase, the portal vein phase and the parenchymal phase, the images of corresponding frames are linearly superimposed to obtain composite images corresponding to the CT enhanced images;the composite images are input to a pre-established liver occupying infection focus area detection model, the liver occupying infection focus area is detected according to an output result, and the liver occupying infection focus area detection model is trained via a 3D convolutional neural network. According to the method, the three-phase images in the CT enhanced images are linearly superposed,image difference between the infection focus area and a normal area can be increased, the model which is trained via the3D convolutional neural network is used for detecting the liver occupying infection focus area, and accuracy of a liver occupying infection focus area identification mode can be improved.

The invention relates to a, especially a perfusion preservation device for liver. The perfusion preservation device for liver includes a water-bath case perfused with a preserving liquid. The device is characterized in that the inside of the water-bath case is provided with a bile duct perfusion tube connected to a bile duct, a hepatic artery perfusion tube in connection with a hepatic artery and a portal vein perfusion tube connected to a portal vein. The ends of the bile duct perfusion tube, the hepatic artery perfusion tube and the portal vein perfusion tube are all connected to a liquid storage pot through a pipeline. And the other end of the liquid storage pot is in connection with a pressure adjustable hydraulic pump that is connected to the water-bath case by a pipeline directly. Earmarked for liver perfusion preservation, the device of the invention is characterized by simple structure, convenient use, long storage and the like.