Liver perfusion device

Abstract

The invention discloses a liver perfusion device, which comprises a main machine, an air-oxygen mixer assembly and a monitoring assembly. A consumable assembly is clamped on a worktable of the main machine, and when different livers need to be perfused, only the consumable assembly needs to be replaced, so that convenience is achieved; the main machine is internally provided with a temperature adjusting assembly in pipeline connection with the consumable assembly, thus the temperature of circulating water entering a first lung membrane oxygenator and a second lung membrane oxygenator for heatexchange can be adjusted through the temperature adjusting assembly, and then liver perfusion can be conducted under different temperature conditions according to the actual needs; and in addition, the main machine has different liver perfusion modes, a user can set hepatic artery and portal vein perfusion methods according to the actual needs, the perfusate oxygenation degree is adjusted according to an air-oxygen mixer, different drugs are injected by a micro-injection pump, and the effects of liver long-term preservation, improvement, repair and the like are achieved.

Description

technical field [0001] The invention relates to the technical field of organ transplantation equipment, in particular to a liver perfusion device. Background technique [0002] Liver transplantation is the only effective treatment for end-stage liver disease of all causes. However, due to organ shortages, transplant waiting lists and pre-transplant mortality continue to be high. Although the number of donors has increased recently, livers suitable for transplantation The number is still limited by cold storage and ischemia-reperfusion injury. [0003] Marginal donor livers are more susceptible to ischemia-reperfusion injury, resulting in a higher incidence of primary reactive power (PNF). Static Cold Storage (SCS) is suitable for high-quality organs, but it is a limiting factor for marginal donor organ viability. Thus, the need for high-risk donor organs has sparked interest in new technologies that could improve preservation quality, assess organ viability, and even repai...

AI Technical Summary

Problems solved by technology

[0005] Liver perfusion can be divided into hypothermia (4-6°C), mild hypothermia (10-13°C), sub-normal temperature mechanical attention (20-25°C), and normal temperature perfusion (37°C) according to the maintenance temperature. Among the main parameters such as liver perfusion mode, perfusion flow rate, pressure, degree of oxygenation, temperature, etc., there is no consensus yet

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