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7 results about "Micro injection" patented technology

Microinjection Microinjection is a technique of delivering foreign DNA into a living cell (a cell, egg, oocyte, embryos of animals) through a glass micropipette. One end of a glass micropipette is heated until the glass becomes somewhat liquified.

Micro liquid sample storage and taking container

The utility model discloses a trace liquid sample storage and taking container which comprises a sample storage unit for directly containing a liquid sample, a sample taking unit arranged at the input end of the sample storage unit, and an injection head protection unit arranged at the output end of the sample storage unit, the sample storage unit comprises a first columnar base body, a sample storage cavity and a micro injection pipe. According to the utility model, the principle of an injector is ingeniously applied, a split detachable connecting system is designed, and all units form a closed container after being assembled, so that the sample transportation is convenient; the technical defect of liquid residue in the traditional taking process is eliminated by adopting a sampling mode of pushing out a micro sample from a micro injection pipe below the sample storage cavity, so that the utilization rate of the sample is improved; in addition, a bucket-shaped input opening is formed in the upper portion of the sample storage cavity, so that sample injection is facilitated.
Owner:TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH

Memristor, method of making a memristor, and artificial synapse device

ActiveCN115955907BPolyelectrolyteSynapse
The application discloses a memristor, a method for preparing the same and an artificial synapse device, and the memristor comprises a glass cone and a polyelectrolyte structure on the inner wall of the glass cone; the glass cone has a first end opening and a second end opening arranged oppositely, the diameter of the first end opening is smaller than that of the second end opening, and the polyelectrolyte structure is located on the inner wall of the first end opening. Thus, the memristor has low power consumption of a picojoule level, a low working potential and high efficiency. When a pulse potential stimulus is applied, the memristor can generate a double-pulse facilitation and a double-pulse inhibition effect similar to a neuron synapse, and due to the existence of an ion effect, the effective regulation of the plasticity of the system can be realized. Further, the signal transduction function based on ions can be realized by being combined with a micro-injection system. In addition, the memristor has excellent stability and designability and the like.
Owner:INST OF CHEM CHINESE ACAD OF SCI

Low-density sperm braking method without PVP medium in ICSI fertilization

The invention discloses a low-density sperm braking method without a PVP medium in ICSI fertilization, and relates to the field of assisted reproduction therapy, and the method comprises the following steps: step 1, diluting a sperm suspension until the density is 0.1 * 10 < 6 > / ml, and placing the diluted sperm suspension in an in-vitro operating solution without PVP; step 2, under an inverted microscope, directly pressing and braking the tail of the sperm in the in-vitro operating fluid by using a microinjection needle, so that the tail of the sperm is folded or curled to deform; and step 3, transferring the braked sperms into operation liquid drops containing ovum to complete microinjection, and performing tail pressing operation in an isotonic operation liquid without PVP (Polyvinyl Pyrrolidone), so that the tail parts of the sperms present visible curled deformation or tail folding. The sperm motility destruction rate is 100% (residual motility is completely prevented from interfering fertilization), and the tail cell membrane rupture rate is 100% (it is ensured that activation factors in sperms are fully released).
Owner:随刘才

Single cell microinjection device

The utility model belongs to the technical field of microinjection, and particularly relates to a single cell microinjection device which comprises a rotating shaft, a mounting frame is mounted at one end of the rotating shaft, rotating shafts are rotatably mounted on two sides of the mounting frame in a penetrating manner, a locking screw is rotatably mounted in one end of a side plate, and a gear groove is mounted at the other end of the rotating shaft. A clamping block is assembled at the bottom end of the limiting rod, and an extension spring is fixedly connected between the limiting block and the supporting plate. A limiting block is lifted upwards, a limiting rod moves upwards, an extension spring is stretched, a clamping block is separated from a gear groove, a rotating shaft drives a mounting frame to rotate, the angle of the injector in the X-axis direction is changed, the angle of the injector in the Y-axis direction is adjusted, a locking screw releases fixation of a rotating shaft, and the injector is rotated through rotation of the rotating shaft; therefore, the angle of the injector can be adjusted at will, the injector can be aligned with target cells more flexibly in the micro-injection process, and the injection effect is improved.
Owner:无锡瑞思医疗科技有限公司

Ultrasonic plasticization microinjection molding apparatus for producing microcantilever beams and method of use

The application provides an ultrasonic plasticizing micro injection molding equipment for producing a micro cantilever beam and a use method, relates to ultrasonic plasticizing molding, and comprises a movable mold fixing plate, a fixed mold fixing plate, a base plate, a protective sleeve, a mold assembly and an ultrasonic head. The application utilizes the base plate to form a centering part, the outer profile of the centering part and the inner profile of the protective sleeve are both inclined surfaces, the centering part and the protective sleeve are centered by utilizing the principle of inclined surface fitting, the blanking pipeline formed by the protective sleeve is fitted with the injection hole surface of the mold assembly to realize the centering of the protective sleeve and the mold assembly, the centering efficiency in the ultrasonic plasticizing micro injection process is improved, and the centering difficulty is reduced. Meanwhile, the mold core unit is also improved, the mold core base and the micro structure cavity are designed in a split mode, different stiffness micro structures are conveniently generated, and the forming length of the micro cantilever beam is increased by means of two side feeding.
Owner:CENT SOUTH UNIV

Microinjection needle storage device

The utility model belongs to medical storage technical field, concretely speaking is a kind of microinjection needle storage device, including lower box and upper box, the upper box one side is hinged on the one side of lower box, and is opened and closed by opening and closing piece to carry out opening and closing operation, the lower box both sides wall all are fixed with multiple sets of locating plate, the locating plate between adjacent is equipped with placing plate by inserting piece, the placing plate top end is equipped with oval slot, the oval slot in fixed attachment has foam pad, the utility model provides a kind of microinjection needle storage device, to the problem of existing microinjection needle needle body storage inconvenience.
Owner:FUJIAN SUNYBIOTECH CO LTD