263 results about "Calcium alginate" patented technology

The invention provides a photo-thermal evaporation material based on black titanium dioxide as well as a preparation method and application of the photo-thermal evaporation material. The preparation method comprises the following steps: mixing urea, absolute ethyl alcohol and tetrabutyl titanate into a solution A, mixing absolute ethyl alcohol, ultrapure water and hydrochloric acid into a solution B, dropwise adding the solution B into the solution A, mixing to form a white colloid, heating in a water bath, drying, and calcining in a nitrogen atmosphere to obtain black titanium dioxide powder; the preparation method comprises the following steps: fully mixing a certain amount of black titanium dioxide, sodium alginate and ultrapure water to form a uniform dispersion liquid, dipping the pretreated polyurethane sponge in the dispersion liquid, and crosslinking with a calcium chloride solution to prepare the photo-thermal evaporation material of the black titanium dioxide-calcium alginate composite hydrogel. The photo-thermal evaporation material breaks through the photo-thermal application bottleneck of traditional titanium dioxide, has excellent evaporation rate and seawater desalination performance, and can effectively remove various printing and dyeing wastewater to obtain clean water.

The invention relates to the technical field of intelligent food production, in particular to a probiotic plant beverage production method and system.The method comprises the steps that mildewed and damaged areas of penthorum chinense pursh, gastrodia elata and other plant raw materials are recognized and removed, the content of reducing sugar is detected, and a traceability identifier is generated; the preparation method comprises the following steps: compounding lactobacillus plantarum A, lactobacillus plantarum B and lactobacillus paracasei, embedding by adopting a sporopollen-calcium alginate core-shell structure, and adjusting the thickness of a shell layer and the concentration of carboxymethyl pachymaran; correcting Arrhenius equation activation energy Ea through bacterial colony density data so as to calculate the attenuation rate k value in the shelf life; after the fermentation liquor is embedded for the second time, QR code labels are generated for products qualified in primary inspection, and RFID temperature and humidity sensing chips are integrated; and pushing real-time shelf lives of qualified finished products, probiotic flora activity reports and traceability identifiers to consumers. According to the invention, the problems of low efficiency, lag in fermentation regulation, backward traceability technology and isolated intelligent technology of the traditional process are solved.

The invention belongs to the technical field of inter-cooling water treatment, and relates to a system and method for cooperatively treating inter-cooling water through multi-stage bypasses. Comprising a gradient filtering unit, a modified adsorption unit and a composite adsorption unit which are sequentially connected, a bottom outlet of the gradient filtering unit is connected with a bottom inlet of the modified adsorption unit; a top outlet of the modified adsorption unit is connected with a top inlet of the composite adsorption unit; the gradient filtering unit sequentially comprises a manganese sand layer and a quartz sand layer from top to bottom; the modified adsorption unit is filled with a coal gangue modified straw biochar material; the composite adsorption unit is internally filled with a microcapsule-embedded calcium alginate-vinasse biochar composite material. According to the invention, three-stage cooperative treatment of iron suspended matter interception, sulfate radical adsorption and iron ion chelation is realized, and low-cost, green and sustainable indirect cooling water deep purification is realized by using the solid waste-based functional material.

The invention belongs to the technical field related to tumors, and discloses a preparation method of self-developing embolism microspheres. Comprising the following steps: producing calcium alginate microspheres through cross-linking, obtaining polyelectrolyte hydrogel microspheres through electrostatic complexation, and obtaining the self-developing embolism microspheres through amino cross-linking. According to the invention, sodium alginate and polyamino acid are used as raw materials for preparation, so that the preservative is safe and non-toxic and has biodegradability, and the degradation product has no toxic or side effect on human body. The microspheres are prepared by adopting an electrostatic spraying method, organic solvents are not used, and the microspheres are green and environment-friendly and have no toxic residues.

The invention discloses a preparation method of immunoglobulin composite liposome nanoparticles with a controlled release characteristic, and belongs to the field of food nutrition and functional factors. Cholesterol and sitosterol are creatively used as auxiliary supports of a lecithin liposome skeleton, the stability of an immunoglobulin liposome nanoparticle structure is improved, the slow release property in the simulation effect process is improved, and a pH response type hydrogel film formed based on electrostatic crosslinking is prepared from calcium alginate and chitosan. A more stable double-layer shell-core structure is formed, so that the stability of embedded immune globulin molecules in gastric juice is further improved, and fixed-point slow release in small intestines is realized.

The invention relates to the technical field of preparation of food additives, in particular to a betacyanin microcapsule as well as a preparation method and application thereof. The preparation method comprises the following steps: jointly dissolving sodium alginate and soybean protein isolate in water to obtain an SA-SPI compound; the SA-SPI compound, CaCO3 and betacyanin are mixed, and a water phase is formed; mixing liquid paraffin, glacial acetic acid and Tween 80 to obtain an acetic acid-containing oil phase; mixing the water phase with the acetic acid-containing oil phase to form a water-in-oil emulsion, and standing to form calcium alginate gel beads; the calcium alginate gel beads are subjected to pre-freezing-freeze-drying treatment, and the betacyanin microcapsules are obtained. The prepared betacyanin microcapsule has the characteristics of controllable particle size, high stability and easiness in industrialization, and the application range of betacyanin is widened. In addition, the preparation method disclosed by the invention is safe and simple to operate, has the advantages of low cost and high benefit, and can be directly applied to large-scale production.

The invention relates to the technical field of soil amendments, in particular to a soil amendment containing earthworm enzymatic hydrolysate and a preparation method of the soil amendment. The soil conditioner containing the earthworm enzymatic hydrolysate comprises the following components: earthworm enzymatic hydrolysate microcapsules and adjuvant particles in a mass ratio of (2-4): 1, the earthworm enzymatic hydrolysate is prepared by performing enzymolysis on fresh earthworm homogenate by compound enzyme, and the compound enzyme comprises cellulase and protease; the wall material of the earthworm enzymatic hydrolysate microcapsule comprises at least one of chitosan, calcium alginate, gelatin and Arabic gum; the auxiliary agent comprises humic acid and inorganic natural minerals. According to the soil conditioner containing the earthworm enzymatic hydrolysate, the earthworm enzymatic hydrolysate is wrapped by the microcapsules, the retention rate of active ingredients in the earthworm enzymatic hydrolysate can be remarkably increased, and the soil condition can be further improved by matching with humic acid and inorganic natural minerals for use.

The present application discloses a rumen-passed Schizochytrium preparation, a preparation method of the rumen-passed Schizochytrium preparation, and an application thereof. The rumen-passed Schizochytrium preparation comprises a core material and at least one layer of coating, wherein the core material comprises calcium alginate microspheres embedded with Schizochytrium cells, and the coating is coated on the core material so that the oil is wrapped in the calcium alginate microspheres, thereby improving the stability of unsaturated fatty acids and reducing the risk of unsaturated fatty acids leaking in the rumen; the preparation method comprises firstly subjecting the Schizochytrium fermentation product to calcium alginate microsphere embedding and immobilization treatment, then drying the immobilized fermentation product to obtain the core material, and finally coating the core material to obtain the rumen-passed Schizochytrium preparation, effectively avoiding the problems of "pipeline blockage" and "oxidation and deterioration of Schizochytrium powder", thereby improving the yield of Schizochytrium powder in the drying process and simplifying the preparation process, and the finally prepared rumen-passed Schizochytrium preparation has an ideal hardness.

The application discloses a degradable cotton soft towel and a preparation method thereof, relates to the technical field of fiber composite materials, and belongs to the patent classification D01F8 / 02. The preparation method comprises the following steps: performing alkali treatment and enzymolysis on Egyptian long-staple cotton fibers to obtain pretreated cotton fibers, and preheating, stretching and setting poly-caprolactone fibers to obtain pretreated poly-caprolactone fibers; mixing and opening the two kinds of fibers, and then air-laying to form a fiber web; constructing a super water-absorbing network by impregnating a main network solution carboxymethyl chitin and oxidized cellulose nanofilament and an auxiliary network dispersion liquid calcium alginate gel microspheres and a hyaluronic acid crosslinking body; forming micron protrusions through hexagonal nickel template hot pressing, and obtaining a base by electrostatic spraying modification of nano silicon dioxide; and obtaining the cotton soft towel through vacuum drying, slitting and sterilization after spraying of an essence liquid. The cotton soft towel has excellent water absorption performance through the synergistic effect of multistage pores, a super water-absorbing network and micro-nano surface modification, and the poly-caprolactone fibers and the cotton fibers used in the cotton soft towel are mixed, and both have good biodegradability.

The invention relates to a decarburization gasification slag green mortar concrete blender and a preparation method thereof. The invention relates to a bacillus pasteurii water-soluble fertilizer which comprises microbial mineralized bacteria liquid of bacillus pasteurii, microcapsules (shells of which are composed of gelatin calcium alginate composite layers and ZrO2 nano-coatings) for encapsulating sodium gluconate, steel slag powder (the particle size is less than 50 microns) subjected to carbon dioxide carbonization treatment, plasma modified powder of which the surface is grafted with a silane coupling agent, and rosin soap, wherein the shells of the microcapsules are composed of gelatin calcium alginate composite layers and ZrO2 nano-coatings; the steel slag powder is subjected to carbon dioxide carbonization treatment; a polycarboxylic acid water reducing agent, a naphthalene water reducing agent and the like. The preparation method comprises the following steps: carrying out mixed culture on the decarburized gasification slag and a microbial mineralized bacterial solution, carrying out plasma treatment on the HPMC, xanthan gum and steel slag powder, mixing the cellulose ether and the starch ether under the assistance of ultrasonic waves, packaging the retarder by a spray drying method, and mixing the modified steel slag powder and the microcapsules according to a specific mass ratio. According to the invention, a microorganism-microcapsule-steel slag synergistic system is combined with a plasma modification technology, so that high performance and greenization of the concrete blender are realized, and the strength, durability and other properties of concrete are improved.

The invention discloses a preparation method of modified mineral powder for adjusting and controlling the viscosity of concrete. The preparation method of the modified mineral powder comprises the following steps: placing vertical mill mineral powder in a hydrochloric acid solution for ultrasonic treatment and infiltration to obtain activated mineral powder; preparing a sodium alginate solution and a calcium chloride cross-linking solution, adding the activated mineral powder into the sodium alginate solution to obtain a mineral powder suspension, and dropwise adding the mineral powder suspension into the calcium chloride cross-linking solution to react to obtain calcium alginate coated mineral powder; the preparation method comprises the following steps: dissolving sodium citrate, glucolactone and active nano silicon dioxide in water to form precursor sol; and adding the calcium alginate coated mineral powder into the precursor sol to obtain the modified mineral powder. The modified mineral powder prepared by the method disclosed by the invention realizes double effects of morphology regularization and viscosity controllability, and has an adjusting and optimizing effect on the viscosity problem of concrete when being applied to the concrete; and the method improves the activity of the mineral powder and the bonding strength of interfaces of the mineral powder and other components at the same time, so that the compactness and the overall strength of the concrete are improved.

The invention relates to the technical field of production and preparation of ammonium tetramolybdate, and particularly discloses a preparation method for producing high-purity ammonium tetramolybdate from low-grade molybdenite. The preparation method for producing the high-purity ammonium tetramolybdate from the low-grade molybdenite comprises the following steps: S1, pretreating the low-grade molybdenite to obtain slag, and roasting the slag to obtain roasted slag; s2, the roasted slag and an ammonia water solution are mixed and leached, and a leaching solution is obtained; s3, an impurity removal agent and an adsorbent are added into the leachate for adsorption and purification, the impurity removal agent comprises mercaptoacetic acid and disodium ethylene diamine tetraacetate, the adsorbent is modified calcium alginate, and after purified liquid passes through an anion exchange resin column, an ammonium molybdate solution is obtained; and S4, adding a nitric acid solution into the ammonium molybdate solution, adjusting the pH value, and then crystallizing to obtain high-purity ammonium tetramolybdate. According to the preparation method, the purity of the ammonium molybdate solution is effectively improved through three procedures, and then the purity of ammonium tetramolybdate prepared from low-grade molybdenite is effectively improved.

The invention relates to the technical field of sewage treatment, and particularly discloses a high-porosity slow-release microelement anti-mineralization sulfur autotrophic denitrification filter material and a preparation method thereof. The sulfur autotrophic denitrification filter material is of a core-shell structure, a complex of sulfur, volcanic rock micro powder and a curing fungicide is used as an inner core, and a hydrophobic polymer coating layer and a porous ceramic bonding layer are sequentially coated on the surface of the inner core; the hydrophobic polymer coating layer is a hydrophobic breathable composite film formed by crosslinking a polydimethylsiloxane prepolymer and calcium alginate. The volcanic rock natural trace elements are utilized to realize waste control by waste, surface mineralization is effectively prevented through the hydrophobic middle layer, the activity of the microbial inoculum is protected in combination with a low-temperature flexible sintering process, and the whole device has the advantages of high porosity, light weight, quick start, long service life, low backwashing energy consumption and the like. Compared with the prior art, the invention has remarkable innovativeness and creativity in the aspects of structural design, material selection and process integration.

The invention belongs to the field of functional polymer materials, and particularly relates to a temperature-sensitive core-shell moisture absorption microsphere based on a biomass source and a preparation method. The preparation method comprises the following steps: dissolving methyl cellulose in water to prepare a solution A; dissolving calcium lactate and LiCl in water according to a mass ratio of 1: (2-14) to prepare a solution B; uniformly mixing the two to obtain functionalized core liquid; and dropwise adding the core liquid into a sodium alginate coagulating bath to carry out ionic cross-linking reaction to form gel microspheres, and washing and freeze-drying to obtain the product. According to the invention, a stable structure with moisture absorption salt / temperature-sensitive methyl cellulose as a core and calcium alginate gel as a shell is constructed in one step through a reverse instillation molding technology. The structure can effectively prevent moisture absorption salt from leaking, efficient release of moisture can be achieved at the low temperature by means of the temperature-sensitive characteristic of methyl cellulose, and desorption energy consumption for taking water from air is remarkably reduced. The raw materials are green, the process is simple, and the prepared microspheres are good in moisture absorption performance, high in cycling stability and suitable for atmospheric moisture collection.

The present application relates to the field of cosmetics, and to a multiphase bead that encapsulates recombinant collagen, a preparation method thereof, and cosmetics. The multiphase bead forms a multi-layer encapsulation structure; the multi-layer encapsulation structure includes: an outer layer, an intermediate layer, and an inner layer; the inner layer includes: a water-soluble active substance; the intermediate layer is an oil phase; the outer layer includes: a wall and a water phase, the water phase encapsulates the oil phase, the wall is encapsulated in the outermost layer, and the wall is calcium alginate. Multiphase bead with a water-in-oil-in-water structure is formed, and calcium alginate forms the outer shell of the multiphase bead. The oil phase is the intermediate phase, sandwiched between the water-soluble active substance and the outer wall; the water-soluble active substance is the innermost phase, encapsulated by the outer layer of calcium alginate and the intermediate oil layer; thereby realizing the preservation of water-soluble active substances such as recombinant collagen by encapsulation technology. It can effectively protect water-soluble active substances such as recombinant collagen, reduce the decomposition rate of water-soluble active substances such as recombinant collagen, and improve the activity of cosmetics.

The invention belongs to the technical field of traditional Chinese medicine preparations, and provides a traditional Chinese medicine granule composition based on rhizoma polygonati and a preparation method and application thereof. A three-layer intelligent response structure design is adopted, a 80-300 nm rhizoma polygonati nano core is prepared through an anti-solvent precipitation technology, a calcium alginate gel buffer layer containing probiotic nutritional factors is constructed through an ionic crosslinking technology, a pH response shell layer is prepared through a fluidized bed coating technology, and the release rate lt in gastric juice is achieved; the cumulative release rate gt in intestinal juice is 10%; according to the invention, the rhizoma polygonati polysaccharide and probiotic nutritional factors are added into the preparation, the precise intestinal targeted release performance is 80%, the drug loading capacity is 15-35%, the coating efficiency is 85-95%, and the technical problems that a traditional rhizoma polygonati preparation is poor in stability, effective components are damaged by gastric acid, and the bioavailability is low are solved; the traditional Chinese medicine composition can be used for treating diseases such as weakness of the spleen and the stomach, functional dyspepsia and dysbacteriosis of intestinal flora, and has wide application value.

The invention relates to the technical field of adsorption materials, in particular to a high-performance seaweed carbon fiber material based on microsphere phase change and a preparation method of the high-performance seaweed carbon fiber material. The method comprises the following steps: carrying out component separation on a seaweed raw material to construct a core-shell structure microsphere phase change unit which takes calcium alginate microspheres as a shell and seaweed active polysaccharide as a phase change medium, introducing sulfonic cellulose nanocrystals and polyacrylonitrile to be blended to prepare a composite spinning solution, dispersing the microsphere phase change unit into the composite spinning solution, and preparing the composite spinning solution. After electrostatic spinning, catalytic carbonization and water vapor activation, the seaweed carbon fiber material is finally prepared, a sulfonic acid group effectively catalyzes a polyacrylonitrile cyclization reaction in the carbonization process, the compactness of a carbon skeleton is remarkably enhanced, and the sulfonic acid group and a microsphere phase change unit generate a multi-stage synergistic enhancement effect, so that the material has ultrahigh strength and high adsorbability at the same time; the technical problem that the mechanical property and the adsorption property of the biomass carbon fiber are difficult to consider at the same time is solved.

This invention relates to an injectable hydrogel, its preparation method, and its applications. It solves the technical problems of short half-life, rapid degradation, and inability to directly form bone by direct systemic injection of disulfiram in existing technologies. The hydrogel contains catecholized calcium alginate, disulfiram, and water. The catecholized calcium alginate contains calcium alginate, a catechol group, and calcium ions. The catechol group is coupled to the side chain of the calcium alginate. The mass percentage content of the catecholized calcium alginate is 0.5-5%; the mass percentage content of the disulfiram is 0.25-2%; and the balance is water. This invention can be used to prepare materials that promote alveolar bone repair and regeneration.

The invention relates to the technical field of radiotherapy auxiliary instruments, in particular to an injectable calcium sodium alginate hydrogel spacer for radiotherapy and a preparation method of the injectable calcium sodium alginate hydrogel spacer. Nano calcium carbonate is used as an adjusting switch, an adjustable mechanical and degradation performance foundation of the hydrogel is laid, and the material is endowed with unique bifunctional characteristics through the synergistic effect of the nano calcium carbonate, a contrast agent iodized oil and a degradation liquid diethylenetriamine pentaacetic acid. The hydrogel can quickly form gel after being injected, keeps long-term structural stability and clear CT imaging capability in vivo, and can monitor the position and form of the hydrogel in a lossless manner; and when the radiotherapy period is finished, the on-demand and rapid degradation of the hydrogel can be realized only by injecting the diethylenetriamine pentaacetic acid, so that the risk of long-term retention is avoided. In-vitro and in-vivo experiments prove that the material has good biocompatibility, can significantly reduce the radiation dose of normal tissues such as rectum and the like, realizes the technical span from invisibility and difficult degradation to visibility and degradability, and has great clinical transformation value.

The application discloses a kind of magnetically responsive hydrogel optical fiber and its preparation and application, belong to medical biomaterial field.The optical fiber includes from inside to outside: polyethylene glycol diacrylate and acrylamide photocrosslinking light transmission core layer;Calcium alginate low refractive index skin layer;Doped nano-magnetic response layer of ferriferrous oxide;And polydopamine grafting polyvinylpyrrolidone lubricating layer.It is prepared by coaxial extrusion and light / calcium step-by-step crosslinking.The structure realizes the spatial isolation and anti-interference of light transmission and magnetic drive, has low background light loss and anti-bending stability, has biomechanics matching, ultra-low friction and magnetic field accurate active navigation ability, solves the pain point that extremely soft optical fiber is difficult to directional intervention.Suitable for deep tissue precise photothermal therapy, in vivo continuous optical sensing and minimally invasive diagnosis and treatment integration and other frontier medical fields.

The application provides a double water plugging profile control plugging agent and a preparation method thereof, and the method comprises the following steps: (1) stirring and uniformly mixing a sodium alginate aqueous solution and glycerol glycidyl ether to obtain a white emulsion; (2) spraying the white emulsion into a calcium ion aqueous solution to perform a reaction, and then performing freeze-drying to obtain calcium alginate microcapsules; and (3) mixing and reacting the calcium alginate microcapsules with a crosslinking agent solution to obtain the double water plugging profile control plugging agent. In the use process, firstly, the calcium alginate microcapsules are injected into a formation, and the microcapsules can firstly perform primary plugging on a dominant pore channel through a physical plugging mode; then, a crosslinking agent solution is further injected into the formation, and the calcium alginate microcapsules can be crosslinked with the crosslinking agent to form an elastic gel with good strength, so that the elastic gel can perform secondary plugging on the plugging position in the form of a gel, and thus the profile control plugging agent in the application has excellent plugging effect in a deep formation.

The invention provides a wet response directional self-cleaning down-proof fabric, a preparation method thereof and a down feather product, the preparation method of the wet response directional self-cleaning down-proof fabric comprises the following steps: S1, adding polyester polyurethane and microcapsules into an organic solvent to obtain a spinning solution; the microcapsule comprises a photocatalyst and a shell layer wrapping the photocatalyst, the shell layer comprises a component A and a component B, the component A comprises at least one of gelatin, Arabic gum, carrageenan and starch, and the component B comprises calcium alginate; s2, a knitted fabric serves as a receiving substrate, the spinning solution is subjected to electrostatic spinning, drying and hot pressing, the knitted fabric contains cellulose fibers, and the mass percentage content of the cellulose fibers in the knitted fabric is larger than 50%. The down-proof fabric capable of conducting moisture in one direction can be prepared, moisture of a quilt is accumulated on one side of the nanofibers in the using process, the self-cleaning function is triggered in the moisture accumulation state, and the down-proof fabric has the advantages of being breathable and soft.

The invention belongs to the technical field of tert-butylamine preparation, and particularly relates to a preparation process for synthesizing tert-butylamine by adopting methyl tert-butyl ether. The preparation process comprises the following steps: preparing calcium alginate microspheres; preparing an SAPO precursor solution; performing composite crystallization; preparing an SAPO-11 carrier; preparing an ammonium type SAPO-11 carrier; preparing a metal supported catalyst; preparing an activated catalyst; methyl tert-butyl ether and liquid ammonia are used as raw materials, and tert-butylamine is prepared under the catalysis of an activated catalyst. According to the preparation process for synthesizing the tert-butylamine by adopting the methyl tert-butyl ether, the process of catalytically synthesizing the tert-butylamine by taking the methyl tert-butyl ether and the ammonia as raw materials follows an acid catalytic cracking nucleophilic addition coupling mechanism, and the prepared hierarchical pore CuZn / HSAPO11 catalyst remarkably reduces the reaction activation energy through the synergistic effect of B acid, L acid and metal active sites; high-activity and high-selectivity catalytic conversion at low temperature is realized, and high-purity tert-butylamine is prepared.

The present invention relates to the technical field of materials of functional polymer networks, and specifically to a magnetic field-induced Janus viscous hydrogel and a preparation method thereof, which are used in the fields of wearable strain sensors and effective waste heat collection and conversion. A preparation method of a magnetic field-induced Janus viscous hydrogel comprises the following steps: S1, obtaining polydopamine-modified ferroferric oxide magnetic nanoparticles; S2, obtaining a hydrogel precursor solution; S3, preparing a magnetic field-induced Janus viscous hydrogel. Based on the magnetic field induction effect and polydopamine-modified ferroferric oxide magnetic nanoparticles, the present invention constructs a Janus hydrogel with different adhesion properties on both sides of an acrylamide / calcium alginate hydrogel, wherein the polyacrylamide / calcium alginate double network structure has good mechanical stability and can give the hydrogel durability.

The invention discloses a metal ion induced alginate aerogel fiber as well as preparation and application thereof. The method comprises the following steps: pre-mixing a sodium alginate solution with a coagulating bath solvent to obtain a uniform spinning solution; extruding the spinning solution into an alcohol coagulating bath through wet spinning to form sodium alginate primary gel fibers; then, introducing the nascent fiber into a calcium ion cross-linking solution with a specific concentration for cross-linking and curing; and finally, drying at normal temperature and normal pressure to obtain the calcium alginate aerogel fiber. The method is simple in process and low in cost, and the obtained fiber has wide application prospects in the fields of adsorption separation, heat insulation, tissue engineering and the like.

The application discloses a sleep drink with emotion regulation function and a preparation method thereof, and comprises the following steps: taking GABA as a core, and coating an enteric layer to obtain GABA enteric microcapsules; embedding GABA-producing probiotics in calcium alginate gel microspheres to obtain probiotic microcapsules; mixing unembedded GABA, the GABA enteric microcapsules and the probiotic microcapsules with a liquid drink base, and adopting a double-dose packaging to obtain the sleep drink; in the application, a three-component design of immediate-release GABA, enteric-slow-release GABA and fast-release probiotic microcapsules is adopted to construct a two-stage delivery system, and the problem that when GABA and GABA-producing probiotics are simply combined in the same drink, the two cannot realize the dual functions of fast-acting and long-acting maintenance due to the non-synchronization of the action time of the two in the body is solved.

This invention discloses a probiotic liquid core ball cultured under polysaccharide confinement, its preparation method, and its application in improving children's intestinal flora. Belonging to the field of probiotic preparation technology, it employs an extrusion method combined with calcium alginate cross-linking technology, using xanthan gum and other thickening polysaccharides to optimize the types and concentrations of polysaccharides to construct the confinement space. The effects of different oxygen conditions on the encapsulation of different proportions of *Lactobacillus rhamnosus* LRa05 and *Bifidobacterium animalis* BLa80 were investigated to obtain the optimal probiotic liquid core ball cultured under polysaccharide confinement. This process is simple, uses safe raw materials, and after confinement culture, the viable bacteria count is ≥10⁹ CFU / g. It can directionally increase the abundance of beneficial bacteria in children's intestines, inhibit opportunistic pathogens, enhance flora diversity and stability, and is suitable for children's dietary scenarios, providing a safe and efficient intestinal flora regulation solution.

This invention discloses a method for cultivating Spirulina, relating to the field of microalgae biotechnology, aiming to overcome the shortcomings of existing technologies in terms of low Spirulina biomass yield and protein content. The method includes: in a first cultivation stage, inoculating Spirulina into a basal culture medium and conducting photoautotrophic cultivation at a light intensity of 5000-10000 lux until the optical density (OD560) reaches 0.6-0.8; in a second cultivation stage, reducing the light intensity to 1000-3000 lux and adding calcium alginate-encapsulated sodium bicarbonate microspheres, cultivating until the algal cell dry weight reaches 1.5-2.0 g / L; in a third cultivation stage, increasing the light intensity to 8000-12000 lux and adding sodium nitrate slow-release granules supported on anion exchange resin. This invention can achieve a synergistic increase in Spirulina biomass dry weight and protein content.

The present invention discloses a high anion conductivity electrodialysis anion exchange membrane resistant to protein contamination, and its preparation method and application. The preparation method comprises the following steps: first preparing a unidirectional gradient cross-linked anti-fouling calcium sodium alginate hydrogel ultrathin film, horizontally coating a poly-2,6-dimethylphenyl ether-based tandem dicationic ionomer solution on one side of the anti-fouling calcium sodium alginate hydrogel ultrathin film, horizontally flipping another anti-fouling calcium sodium alginate hydrogel ultrathin film and attaching it to the membrane, constructing a sandwich structure composite membrane, removing volatiles, and fully soaking the membrane in distilled water. The present invention effectively solves the instability of the anti-fouling structure of existing modified anion exchange membranes and the contradiction between homogeneous ionomer membranes in achieving both anti-fouling and conductivity, thereby obtaining a dense anion exchange membrane with good basic performance and high anion conductivity for anti-protein contamination, thereby meeting the comprehensive performance requirements of anion exchange membranes in the desalination electrodialysis process of salt-containing protein systems.