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1125 results about "Calcium alginate" patented technology

Calcium alginate is a water-insoluble, gelatinous, cream-coloured substance that can be created through the addition of aqueous calcium chloride to aqueous sodium alginate. Calcium alginate is also used for entrapment of enzymes and forming artificial seeds in plant tissue culture.

Enteric-coated multilayer encapsulated probiotic microcapsule and preparation method thereof

The invention discloses an enteric-solubility multilayer encysted bacterium microcapsule and making method in the biological agent technical domain, which is characterized by the following: adopting sodium alginate, calcium chloride and chitose as clad material of microcapsule; making lactic acid bacteria or bifidobacteria as core-clad material; proceeding ionic exchange for sodium alginate and calcium chloride; forming second clad on the surface of calcium alginate through different isoelectric points of calcium alginate and chitose; freezing at low temperature to obtain the product.
Owner:JINAN SYNBIOTICS BIOENG

Chitosan collagen and calcium alginate compounded spongy biological dressing and its preparation process

The composite spongy biological dressing contains chitosan, collagen and calcium alginate with weigh tmixing ratio o f 0.5-8:0.5-8:0.1-8. Its preparation method includes the following steps: selecting chitosan and collagen type I, adding calcium alginate, compounding and cross-linking, using buffer solution to make neutralization, emulsifying, prefreezing and one-step freeze-drying so as to obtain the invented dressing with good biological compatibility and strong adhesion property. Said invented dressing possesses active function of promoting wound healing and hemostatic action, can be combined with anti-bacterial medicine to obtain gene engineeirng dressing for curing wound surface infection, also can be combined with active growth factor or active cell to form gene engineering dressingfor curing intractable ulcer and burn wound surface.
Owner:JIANGXI RUIJI BIOTECH CO LTD

Polymeric hydrogel grafted on fibers by calcium ion crosslinking and preparation method thereof

The invention provides a polymeric hydrogel grafted on fibers by calcium ion crosslinking and a preparation method thereof. The polymeric hydrogel comprises the following components in percentage by mass: 3-8% of sodium polyacrylate grafted fiber, 0.96-4% of sodium alginate, 0-2% of water-solubility polymeric additive, 0.96-8% of calcium chloride and 75-95% of deionized water. The preparation method comprises the following steps: grafting polyacrylic acid on fibers by ultraviolet radiation; neutralizing with sodium hydroxide to obtain sodium polyacrylate-grafted fibers; soaking sodium polyacrylate-grafted fibers in an aqueous sodium alginate solution; taking out and scraping off the superabundant adherent viscous solution; and crosslinking in an aqueous calcium chloride solution to obtain the calcium alginate hydrogel grafted on the fibers. The preparation method is simple to operate, and the prepared polymeric hydrogel grafted on fibers has application prospects in the fields of adsorption separation, drug control and release, immobilized enzyme, tissue engineering and the like.
Owner:TIANJIN POLYTECHNIC UNIV

Microfluidic technology for one-step continuous preparation of calcium alginate microgel

The invention relates to a microflow droplet technology-based method for one-step continuous preparation of multi-chamber calcium alginate microgel for immobilization of bioactive substances. The method realizes high-throughput continuous production of a microgel material. The method comprises forming a parallel and stable flow field through different hydrogel prepolymer solutions in a microfluidic channel, pouring the hydrogel prepolymer solutions for forming different chambers of the microgel into a microfluidic chip to form water phase solutions of multiple phase parallel fluids, mixing thewater phase solutions and an immiscible fluid (oil phase) through a T-shaped channel or a fluid focusing design to obtain water-in-oil emulsion drops and then alginic acid in the drops is linked immediately so that multi-chamber microgel is prepared, and cleaning the emulsion drops on the microfluidic chip so that the microgel is fast conveyed into a water phase. The method realizes one-step preparation of the calcium alginate microgel immobilized with bioactive substances and is suitable for industrial application.
Owner:SHENZHEN HUA NOVA BIOTECH LTD

Method for producing antimicrobial calcium alginate fiber

The invention discloses a method for manufacturing an antimicrobial calcium alginate fibre. A sodium alginate is used as spinning stock solution; in a solidification bath containing an antimicrobial agent, the antimicrobial calcium alginate fibre is obtained by a wet-method spinning process; and the antimicrobial agent is a cationic compound which is combined with large molecules of the calcium alginate fibre through ionic bonds. The antimicrobial calcium alginate fibre obtained by the method has no toxicity and no side effect on human body; the antimicrobial agent and the large molecules of the fibre are combined by the ionic bonds in order that the antimicrobial agent has long-lasting antimicrobial function; in addition, the fibre retains the excellent quality of the calcium alginate fibre, has excellent hygroscopic property and good mechanical property, can be used for manufacturing medical dressings, has the advantages of convenient use, comfortable application and good ventilation, the acceleration of the healing of wound, the relieving of the pains of patients and the like, can be also used for manufacturing clothing and industrial textiles by pure spinning or blended spinning with cotton, mucilage glue, bamboo pulp, fur, ramie, soybean protein fibre and the like.
Owner:山东康康新材料科技有限公司

Preparation method of carbon quantum dot containing calcium alginate gel for detecting copper ions

The invention relates to a detection technology of copper ions, and in particular relates to a preparation method of a reduced carbon quantum dot containing calcium alginate gel for detecting copper ions. The preparation method of the carbon quantum dot containing calcium alginate gel for detecting the copper ions comprises the following steps of: preparing fluorescent carbon quantum dots; neutralizing the fluorescent carbon quantum dots, adding sodium borohydride into the neutralized fluorescent carbon quantum dots to perform reduction; mixing deionized water with the neutralized fluorescent carbon quantum dots at equal volume, and adding sodium alginate into the mixture to obtain a sodium alginate sol; and spraying a calcium ion solution to the surface of the sol or soaking the sol into the calcium ion solution to perform crosslinking, and drying to obtain the calcium alginate gel. By using the characteristics that the carbon quantum dots have fluorescent characteristics, the fluorescence of the carbon quantum dots is enhanced after reduction, and the calcium alginate can enhance the fluorescent characteristics of the carbon quantum dots, when the copper ions are detected, the cost of an adopted fluorospectro photometer is low, the sample preparation and treatment steps are simple and easy to operate, and the detection sensitivity is high, so that the calcium alginate gel can be widely used for detecting the copper ions.
Owner:ZHONGBEI UNIV

Microbial immobilization method

The invention relates to a microorganism immobilization method. The method comprising the following steps of: taking a sodium alginate solution containing dense suspending microorganisms and nano calcium carbonate as disperse phases, taking atoleine or vegetable oil as a disperse medium, and taking Span85 as a surfactant; forming droplets through agitation and emulsification; then preparing calcium alginate bead gel embedding the microorganisms through a gel initiator of glacial acetic acid; forming a polycation-polysnion complexing membrane through the reaction and cross linking of the bead gel and a chitosan solution; and finally forming a sodium alginate-chitosan microcapsule embedding the microorganisms. The method has mild conditions in the preparation process, simple requirements on apparatuses and equipment, easy mass production, good maintenance of the activity of the microorganism cells in the preparation process, and lower cell leakage rate. Thus, the technology is suitable for the immobilization embedding of a plurality of microorganisms such as yeast, bacillus coli, lactic acid bacteria, nitrobacteria, etc., thereby realizing high-density and large-scale microorganism culture.
Owner:DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI

Preparation method of nanosilver-carried calcium alginate antibiotic medical dressing

The invention relates to a preparation method of an antibiotic medical dressing, and concretely relates to a preparation method of a nanosilver-carried calcium alginate antibiotic medical dressing. The problems of bad antibiotic performance, bad wettability, weak permeability and weak mechanical properties of present chitosan base medical dressings are solved in the invention. The preparation method comprises the following steps: carrying out chemical reduction of a silver nitrate solution by using sodium alginate as a stabilizing agent and a dispersant and sodium borohydride as a reducing agent to prepare a nanosilver sol, adding sodium alginate into the nanosilver sol, dumping the sodium alginate solution mixed with nanosilver particles into a culture dish to form a film, and crosslinking the sodium alginate film carried with nanosilver ions by using calcium chloride to obtain the calcium alginate dressing carried with the nanosilver ions. The antibiotic medical dressing has the advantages of rapid and efficient control of severe hemorrhage, antibiotic performance, good moisture absorption performance, good water steam transmittance, good biocompatibility, biodegradability, wound healing promotion capability, low price, simple operation, and suitableness for the scale production.
Owner:HARBIN ENG UNIV

Composite microsphere containing hydroxyapatite and preparing method thereof

InactiveCN1594201ASolve the problems of low mechanical strength and brittlenessHigh mechanical strengthApatiteMicrosphere
The invention provides a composite microsphere containing hydroxyapatite and preparing method thereof, wherein the weight percentage of its constituents include sodium alginate 20-50%, hydroxyapatite 40-70%, gelatin 0-13%, acacia gum 0-13%, the preparing process consists of formulating organic phase, charging the microsphere into the organic phase, agitating, charging calcium chloride solution, washing with water, immersing in water or 2.5% of calcium chloride solution for storage.
Owner:TIANJIN UNIV

Immobilization pseudomonas aeruginosa as well as preparation method and application thereof

The invention belongs to the treatment field of heavy metal polluted wastewater and particularly discloses immobilization pseudomonas aeruginosa. The immobilization pseudomonas aeruginosa comprises pseudomonas aeruginosa live bacteria and a mixing carrier used for fixing the bacteria, wherein the mixing carrier is a spherical object embedded with the live bacteria and mainly comprises the following compositions of polyvinyl alcohol, calcium alginate and multi-wall carbon nano-tube in the mass ratio of 50-60:30-40:1.6-6. The preparation method of the immobilization pseudomonas aeruginosa comprises the following steps of: firstly, preparing a mixed solution by mixing the polyvinyl alcohol, the calcium alginate, the multi-wall carbon nano-tube and water, uniformly heating and stirring, and obtaining an immobilization reagent by standing; secondly, adding a pseudomonas aeruginosa into an immobilization reagent to obtain a bacteria solution, and dripping the bacteria solution into a calcium nitration solution to obtain an immobilization pseudomonas aeruginosa microsphere; and finally, obtaining the immobilization pseudomonas aeruginosa through frozen-thawed treatment. The immobilization pseudomonas aeruginosa can reduce hexavalent chromium to trivalent chromium, has the advantages of high efficiency, favorable effect, also simple operation and no secondary pollution.
Owner:HUNAN UNIV
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