Preparation method of nanosilver-carried calcium alginate antibiotic medical dressing

Abstract

The invention relates to a preparation method of an antibiotic medical dressing, and concretely relates to a preparation method of a nanosilver-carried calcium alginate antibiotic medical dressing. The problems of bad antibiotic performance, bad wettability, weak permeability and weak mechanical properties of present chitosan base medical dressings are solved in the invention. The preparation method comprises the following steps: carrying out chemical reduction of a silver nitrate solution by using sodium alginate as a stabilizing agent and a dispersant and sodium borohydride as a reducing agent to prepare a nanosilver sol, adding sodium alginate into the nanosilver sol, dumping the sodium alginate solution mixed with nanosilver particles into a culture dish to form a film, and crosslinking the sodium alginate film carried with nanosilver ions by using calcium chloride to obtain the calcium alginate dressing carried with the nanosilver ions. The antibiotic medical dressing has the advantages of rapid and efficient control of severe hemorrhage, antibiotic performance, good moisture absorption performance, good water steam transmittance, good biocompatibility, biodegradability, wound healing promotion capability, low price, simple operation, and suitableness for the scale production.

Description

technical field

[0001] The invention relates to a preparation method of an antibacterial medical dressing. Background technique

[0002] Skin trauma is a common clinical disease. In order to avoid bacterial infection and other external factors, protect and promote wound healing, and promote tissue repair, various wounds and wound surfaces are often temporarily covered with medical dressings. The commonly used clinical dressings are mainly made of gauze, medical absorbent cotton and other materials. Although the cost is low, the source of raw materials is wide, the production is simple, and it has strong absorption capacity, but the hemostatic effect is not good, and the moisturizing effect of the non-invasive surface is easy to cause secondary damage. The accumulation of fluid on the surface can easily cause bacterial infection and so on.

[0003] Sodium alginate is a linear anionic natural polysaccharide extracted from seaweed, composed of β-D-mannuronic acid (M) and α-L-g...