1353results about How to "Good slow release" patented technology

The present invention provides one kind of water gel containing natural high molecular material and its preparation process. The water gel has cross-linking degree of 70-95 % and water absorption of 500-80000 %, and contains natural high molecular material or its derivative selected from chitin, chitin derivative, chitosan, chitosan derivative, carrageenin, etc. The water gel may have synthetic high molecular material, inorganic filler, cross-linking sensitizer, medicine and other assistant added. It is prepared through radiation cross-linking, with the radiation dosage being 10-40 kGy. The water gel of the present invention has high water absorption, high flexibility, good medicine slow releasing performance, and may be used in wound dressing, etc.

The invention discloses a double-layer coated essence microcapsule and a preparation method thereof. The essence microcapsule takes an oil soluble liquid essence as a capsule core, a gelatin modified amino resin composite material as a first-layer capsule wall and an acrylate polymer as a second-layer capsule wall, wherein a grafting transition area is formed by graft copolymerization of gelatin and acrylate between the first-layer capsule wall and the second-layer capsule wall. The preparation method comprises a step of prepolymer compounding, emulsification dispersion, microcapsule continuous double-layer coating and post-treatment. Compared with a single-layer coated microcaposule, the essence microcapsule has the advantages that the slow release performance, the heat resistance performance and the capsule wall material mechanical property are greatly improved, and the essence microcapsule can be used for most of microencapsulated essence products processed by heat extrusion molding of high molecular materials.

The invention provides a preparation method of drug and protein sustained-release alginate hybrid gel. The preparation method comprises the steps of preparing calcium alginate hydrogel, then soaking the calcium alginate hydrogel in inorganic salt solutions including trisodium phosphate, diammonium hydrogen phosphate, sodium silicate, sodium carbonate, sodium oxalate and the like at certain concentration to swell for a certain period of time, and soaking the swelled calcium alginate hydrogel into an aqueous solution of drugs and proteins with calcium ions at certain concentration for crosslinking for a period of time, thus obtaining the drug and protein sustained-release alginate hybrid gel. The calcium alginate hydrogel disclosed by the invention can be in the shape of a membrane, a microballoon, a fiber and the like. The method disclosed by the invention is simple to operate and does not adopt any poisonous and harmful solvent; the activity of the immobilized protein is high; the materials are good in biocompatibility; and the drug and protein sustained-release alginate hybrid gel is good in slow release performance, and has good application prospect in the fields of tissue engineering, controlled release, medicine and health, and the like.

The invention discloses a mint-releasing cigarette filter tip and a production technique thereof, relating to a cigarette filter tip and the production technique thereof. The mint-releasing cigarette filter tip contains tow material in which cotton thread infused with mint essence solution is wrapped; film-forming material solution is adsorbed at the outer layer of the cotton thread infused with mint essence solution; mint essence is added in the film-forming material solution; and the film-forming material includes natural macromolecular material and synthetic macromolecular material. The mint-releasing cigarette filter tip has the advantages that: 1, adopting membrane technology, mint is low in volatility at room temperature, so the mint can be effectively released when taking the cigarette;2, the production technique is simple; 3, the mint-releasing cigarette filter tip is not changed in performance; 4, the mint-releasing cigarette filter tip can be preserved for more than one year at room temperature; 5, the mint-releasing cigarette filter tip is low in cost.

The invention discloses an environment-friendly coated fertilizer and a preparation method thereof, and relates to the technical field of sustained/controlled release fertilizers. The environment-friendly coated fertilizer comprises fertilizer particles and a coat coating the surfaces of the fertilizer particles, wherein the controlled release coat is prepared from polyaldehyde oxidized polysaccharide and protein, and in order to protect the controlled release coat, the controlled release coat is coated with super absorbent resin. The environment-friendly coated fertilizer provides required various nutrients for plants, improves the sustained release performance of nutrient elements of the fertilizer, and has multiple functions of water absorbing and retaining, sustained release, soil conditioning and the like by combining the absorbent resin.

The invention discloses a method for preparing high-temperature resistant essence microcapsules, which comprises the following steps: preparing aqueous solution of gelatin and aqueous solution of Arabic gum by gelatin and Arabic gum respectively, then adding oil-soluble essence into the aqueous solution of Arabic gum and performing homogenization and emulsification on the solution, and uniformly mixing the emulsified solution and the aqueous solution of gelatin to obtain emulsified liquid; adjusting the pH of the emulsified liquid to 4.15-4.17 by using edible acetic acid; dissolving a curing agent glutamine transaminase in water, and then mixing solution of the curing agent and the emulsified liquid to perform curing; filtering the cured emulsified liquid, discarding the supernate, and collecting the sediment; dissolving a wall material obtained by mixing Arabic gum, malt dextrin, glucose and isolated soy protein in the water, then adding the collected sediment into the solution of wall material to be uniformly mixed, and preparing the mixture into the high-temperature resistant essence microcapsules by adopting a spray drying method. The method prepares the oil-soluble essence into the microcapsules so as to keep the primary fragrance of the essence and ensure the using effect in high-temperature processing.

The utility model relates to a new drug-loading controlled-releasing microcapsule and a preparation method thereof, which belongs to the field of the material preparation and the medicine application, and is expected to have applications in the filed of the food, the spice, the makeup, the pesticide, the organism and other fields. A new micro encapsulant system of medicine / silicon dioxide with the core-shell composite structure is prepared by means of the emulsion in-situ encapsulation and synthesis, and can embed the medicine with different molecular dimensions into the cavity, that makes the new micro encapsulant system become a warehouse for medicine storage indeed, and increases the medicine load; and the release rate of the medicine can be regulated by means of the shell structure to reach the goal of slow release.

The invention discloses a chicken manure fermentation organic fertilizer, which is prepared from the following raw materials: chicken manure, straw powders, konjak flour, corn flour, cellulose, zeolite, humic acid, potassium dihydrogen phosphate, urea, peat soil, a leavening agent, a soil improvement agent, a film coating agent, potassium sulfate, borax and calcium superphosphate. The above raw materials are subjected to the integrated treatment of anaerobic fermentation and aerobic fermentation, so that the organic fertilizer is prepared through the fermentation of the chicken manure. The chicken manure fermentation organic fertilizer is complete in fermentation effect, and is capable of killing plant pathogenic bacteria, eggs, weed seeds and other harmful microorganisms in the chicken manure, and generating a large amount of nutrients beneficial to the plant growth and the plant absorption. The process is simple and easy to implement. The raw materials of the prepared organic fertilizer are rich in nutrition. Meanwhile, the prepared organic fertilizer is high in fertilizer efficiency and rich in nutrition, and can coordinate the soil nutrient balance, improve the soil nutrient, promote the plant growth, increase the plant yield and improve the plant quality.

The invention belongs to the technical field of fertilizers and specifically relates to a water-retention and slow-release fertilizer. The water-retention and slow-release fertilizer comprises the following raw materials in parts by weight: 70-80 parts of coated slow-release fertilizer or low-solubility slow-release fertilizer, 15-20 parts of water retention agent, 1-2 parts of biological bacteria, 5-10 parts of humic acid and 5-15 parts of soil conditioner. The prepared water-retention and slow-release fertilizer disclosed by the invention has the advantages of low cost and simplicity and convenience in application, and can adjust the water absorbency of the fertilizer according to different crops, soil, climate and other conditions and be widely applied to grain crops, cash crops, horticultural plants and the like. The water-retention and slow-release fertilizer disclosed by the invention has long effective period, and can greatly reduce the loss of the fertilizer caused by volatilization and eluviation, enable the limited fertilizer and water to be fully absorbed and utilized by the plants, achieve the integration of the water and the fertilizer and improve the soil. Through the application of the water-retention and slow-release fertilizer, the irrigation cost of farmland can be reduced and the high-efficient water conservation purpose can be achieved. The water-retention and slow-release fertilizer disclosed by the invention can greatly improve the utilization rate of nutrients and effectively control the pollution of the crops and an environment caused by the application of the fertilizer.

The invention relates to a novel passive targeting nano emulsion with skin whitening effect and a preparation method thereof. The invention uses a novel passive targeting transdermal delivery dosing system TDDS-nano emulsion as a carrier of a function component for whitening or lighting the skin, uses different physical and chemical properties, action mechanism and actual effect of each skin whitening function component, especially the action advantages of certain novel skin whitening function components, and provides skin whitening effect nano emulsion systems with two joint applications in morning and evening matched with each other. The two joint applied nano emulsion systems not only have minimum spherical grains, extremely even distribution of nano-scale grains, remarkable passive targeting function, good transdermal absorption and strong penetrability, but also have extremely even, exquisite, smooth and glossy texture of the nano emulsion, is quite comfortable after coating on the face or the skin, has no stimulus and good stability; and the nano is light yellow, beautiful in appearance, bright and transparent, clear and crystalline, has light opalescence, and is adhesive but not sticky, thick but not heavy, oily but not greasy.

The invention discloses a slow release fertilizer used for rice planting. The fertilizer is prepared from urea, monoammonium phosphate, potassium chloride, ammonium chloride, diammonium phosphate, calcium triple superphosphate, zinc sulfate, ammonium molybdate, ammonium nitrate complex, gamma-polyglutamic acid, attapulgite, modified sepiolite powder, kaolin powder, talcum powder, stannous chloride, sodium bisulfite, boric acid, oxalic acid, cow dung, soybean meal, furfural residues, corn straw, rape-seed cakes, bagasse, fly ash, medical stone, humic acid, EM strain, hydroxymethyl cellulose and modified sustained-release preparation. The invention further provides a preparing method of the slow release fertilizer used for rice planting. The slow release fertilizer used for rice planting has excellent slow release performance, can provide rich nutrient substances, promote the growth of the rice, increase the yield of the rice, and improve the quality of the rice.

The invention discloses a novel polysaccharide gel water retaining and slow release fertilizer and relates to the technical field of slow release fertilizers. The fertilizer consists of fertilizer particles and film covered water retaining and slow release layers covering on the surfaces of the fertilizer surfaces, wherein materials for forming the film covered water retaining and slow release layers comprise tamarindus polysaccharide and plant polysaccharide, and the plant polysaccharide is in crosslinking with the tamarindus polysaccharide and is one or several materials in starch, soluble cellulose, guar gum and konjac polysaccharide. A high molecular gel reticular structure formed by the pure nature plant polysaccharide is used for building a slow release system, so the novel polysaccharide gel water retaining and slow release fertilizer integrating the water retaining and the slow and controlled release is obtained, and the fertilizer has the advantages that stronger water absorption and water retaining performance, the nutrient loss is little, nontoxicity is realized, the biodegradable and environment-friendly effects are realized, and the like. The novel polysaccharide gel water retaining and slow release fertilizer particularly has good market prospects in regions of drought, water lack or regions with great daily evaporation capacity.

The invention relates to a slow-release compound fertilizer and a production method thereof. The slow-release compound fertilizer comprises a water-soluble granular fertilizer core and a coating layer, wherein the coating layer includes 2-3 coating layers; and the content of N, P2O5 and K2O which are contained in the slow-release compound fertilizer is respectively 4%-33%, 4%-30% and 0%-30% accounting for the total weight of the slow-release compound fertilizer. According to the invention, the coating layer of the slow-release compound fertilizer is not made from high-molecular materials or other organic polymers, the cost is reduced, and the secondary pollution of the organic polymer or the high-molecular materials on the soil is prevented; and a product formula is flexible, a production process is simplified by integrating the preparation process and compound (mixed) fertilizer production process of the slow-release compound fertilizer into a whole, the equipment investment is saved, the convenience for realizing large-scale industrial production is achieved, and no three wastes are discharged in the production process. Compared with the prior art, the slow-release compound fertilizer disclosed by the invention enhances the slow-release effect to a certain degree and meets the requirements of a chemical industry standard HG/T 4217-2011.

The invention discloses a soil improvement type biological organic composite coated fertilizer which is characterized by being prepared from the following raw materials in parts by weight: 67-70 parts of human and animal excreta, 25-30 parts of riverway sludge, 8-10 parts of diatomite, 25-28 parts of diammonium phosphate, 12-15 parts of magnesium sulfate, 15-19 parts of potassium chloride, 45-49 parts of furfural residue, 40-45 parts of animal bone meal, 50-54 parts of rice husk, 35-40 parts of saw dust, 27-29 parts of urea, 3-5 parts of amino acids, 1-2 parts of sodium tetraborate, 7-8 parts of an EM fungicide, 7-9 parts of a soil improvement agent and a proper amount of water. The fertilizer disclosed by the invention is balanced in nutrition, contains inorganic elements and mineral substance components such as the riverway sludge and diatomite, the nutrient needed by plant growth is met, the soil is activated, and the water and fertilizer retaining properties of the soil are improved; and due to the addition of the soil improvement agent, the fertilizer has the effects of improving the efficiency and promoting plant nutrition absorption. According to the fertilizer disclosed by the invention, the urea melting and coating process is adopted, the slow-release effect is obvious, and the fertilizer efficiency is lasting.

The invention discloses a preparation method of a synthetic type polycarboxylic acid water reducer. The synthetic type polycarboxylic acid water reducer has a solid content of 40-50%, and is prepared from the following raw materials in parts by weight: 100 parts of unsaturated polyoxyethylene ether, 7-15 parts of unsaturated acid, 4-10 parts of unsaturated ester, 1-3 parts of an amide derivative, 0.5-2 parts of an oxidant, 0.2-1.2 parts of a chain transfer agent, 0.3-2 parts of a reducing agent, 0.1-1 part of a crosslinking agent, 0.01-0.1 part of ferrous sulfate heptahydrate, 5-10 parts of a commercially available mud-resistant auxiliary agent, 90-130 parts of deionized water and an appropriate amount of liquid caustic soda. The preparation method disclosed by the invention adopts a normal-temperature oxidation-reduction initiating system to synthesize the synthetic type polycarboxylic acid water reducer which not only has functions of water reduction and slump loss resistance, but also has functions of mud resistance and early strength, heating is not needed for reaction, the energy consumption is reduced, and the production cost is greatly reduced.

The invention relates to a spice slow-release filter tip additive with a polymer covering film as well as a preparation method and an application thereof, which belong to the technical field of cigarettes. The spice slow-release filter tip additive with the polymer covering film is of a three-layer sandwich structure, an inner core is made from porous materials, the covering film is made from polymers, and spices are fixed in a middle layer of the additive. The filter tip additive is added to a cigarette holder in an adding manner of ordinary filter tip particles, so as to prepare a cigarette. When the cigarette is smoked, the position of the particles in a filter tip is kneaded by hand, so that the spices in a sandwich layer are released, the aroma and flavor of smoke are increased, and the quality of the cigarette is increased. After the filter tip additive which is prepared by using the method is added to the cigarette, the non-burning section of the cigarette can be effectively perfumed, so that the aroma in an early manufacturing stage is prevented from being quickly volatilized, and the aroma and flavor of the cigarette can be kept for a long time.

The invention discloses compound fertilizer having growth promotion and high slow-release properties and used for rice planting. The compound fertilizer is prepared from raw materials as follows: ammonium nitrate, monopotassium phosphate, urea, urea phosphate, calcium superphosphate, ammonium dihydrogen phosphate, potassium sulfate, magnesium sulfate, potassium nitrate, amino sodium dicarboxylate, Trichoderma, yeast powder, straw fermentation bacteria, cellulase, potassium mineral powder, rare earth, low-rank coal, silico-calcium powder, turf powder, fly ash, pine sawdust, kaolin, rice hull powder, poultry manure, maize straw, blue-green alga powder, dolomite, diatomite, calcite, humic acid, lignin, EDTA (ethylene diamine tetraacetic acid) chelate zinc, amino acid chelated molybdenum, dicyandiamide, phosphoric triamide and a modified slow-release agent. The invention further discloses a preparation method of the compound fertilizer having growth promotion and high slow-release properties and used for rice planting. The compound organic fertilizer has outstanding slow-release performance and can effectively increase the rice yield and improve the rice quality.

Compositions and systems for topical ophthalmic application, which include an aqueous mixture of steroidal and non-steroidal anti-inflammatory agents in a flowable mucoadhesive polymer, for treating inflammation and inflammatory conditions of the eye.

The invention provides an in-situ phase change gel slow release system taking a phospholipid as a substrate, and provides a preparation method thereof. A high-concentration phospholipid slow release preparation is prepared from a high-concentration (50-85 percent) phospholipid, a bioactive ingredient, ethanol solutions of different concentrations and/or injection oil with a simple method, and has the characteristics of high biocompatibility, small untoward effect, remarkable slow release effect and suitability for various administration forms such as hypodermic injection, intramuscular injection, external administration and the like; the amount of a coated medicament can be conveniently adjusted according to the clinical dosage of a medicament; and the in-situ phase change gel slow release system has a wide application prospect.

The invention aims at providing a method for preparing a multi-drug multi-coating eluting intravascular stent through ultrasonic atomizing and spraying, wherein VEGF, SZ-21 and other protein drugs, taking chitosan as a drug carrier, form a first coating; the second layer is a shielding layer, which adopts a polymer poly L lactic acid (PLLA) and can be added with polyethylene glycol (PEG) in different proportions to control release speed of drug; the third layer is lipid soluble medicine, such as rapamycin, which uses PLLA as a drug carrier; and a coating at the top end of the fourth layer, same as the second layer, is a shielding layer. Two uniform drug polymer coatings can simultaneously load multiple drugs, and the release speed of the drug can be regulated and controlled by regulating a mixing proportion of the PEG and the polymer, so as to inhibit restenosis and to reduce formation of thrombus simultaneously.

The invention discloses a water-retaining and slowly-release compound fertilizer and a preparation method thereof. The water-retaining and slowly-release compound fertilizer is prepared from the following components in parts by weight: 60-75 parts of chemical fertilizers, 1-6 parts of a water-retaining agent and 19-39 parts of filler, wherein the chemical fertilizers are at least two of a nitrogen source fertilizer, a phosphorus source fertilizer and a potassium source fertilizer; the water-retaining agent is at least one of polyacrylamide, sodium polyacrylate and sodium carboxymethylcellulose; the filler is at least one of bentonite, attapulgite, kaolin, talcum powder and gypsum powder. The preparation method comprises the following steps: 1) mixing the chemical fertilizers, the water-retaining agent and the filler to obtain a mixture; 2) adding water in the mixture and granulating; stopping adding water when small particles are formed, then adding the filler powder, granulating, and finally drying to obtain the water-retaining and slowly-release compound fertilizer. The water-retaining and slowly-release compound fertilizer disclosed by the invention has a water-retaining property and a slowly-release property, and is capable of reinforcing the water-retaining and water-holding capacities of soil, increasing the utilization rate of water resources, increasing utilization rate of the fertilizers, reducing nutrient loss, resisting drought, and reducing the pollution of fertilization to an ecological environment; the preparation method is simple and easy to process and produce.

The invention discloses a biomass charcoal-enveloped controlled-release fertilizer and a preparation method thereof. The fertilizer is prepared from the raw materials of, by weight: 20-30 parts of rice husk, 45-70 parts of a 3-6wt% sodium hydroxide solution, 10-15 parts of corn straw, 20-30 parts of urea, 15-25 parts of attapulgite, 10-15 parts of ammonium bicarbonate, 8-12 parts of potassium sulfate, 4-6 parts of trace elements, 15-25 parts of a calcium-magnesium-phosphorous fertilizer, 6-8 parts of a binding agent and a proper amount of water. Specifically, the enveloped controlled-release fertilizer is prepared with a rice husk and plant straw sealed charring technology and with the binding agent prepared from polyvinyl alcohol. As a result of tests, the biomass charcoal-enveloped controlled-release fertilizer has a significant controlled release effect. According to different plant requirements, the controlled-release speed can be adjusted by adjusting the proportion of the added enveloping agent. Most of the components in the enveloping agent is biomass charcoal, such that the pollution degree to the environment is almost zero. Also, a fertilizer dose is reduced, and fertilizer utilization rate is greatly improved.