12 results about "Symbiotic bacterium" patented technology

The invention discloses klebsiella aerogenes HW2024 and application of the klebsiella aerogenes HW2024 in preparation of drugs for treating allergic rhinitis. The preservation number of the klebsiella aerogenes HW2024 is CCTCC NO: M 20252524. The Klebsiella aerogenes disclosed by the invention is a symbiotic bacterium, and is relatively safe and easy to obtain, so that the treatment cost of AR patients can be greatly reduced, and a new treatment choice is provided for AR treatment; the pharmaceutical preparation for treating allergic rhinitis is simple and convenient in administration route, easy to operate and convenient for patients to use.

Compositions for use in preventing or treating an infection of the nasal passages, sinuses, or both of a subject are described. The compositions include one or more peptoid compounds in an amount effective to prevent or treat the infection in the nasal passages, sinuses, or both. The compositions include the one or more peptoid compounds in an amount effective to inhibit one or more pathogenic bacteria, pathogenic fungus, or pathogenic virus in the nasal passages, sinuses, or both, while having relatively little or no activity against commensal bacterial species, commensal fungal species, commensal viral species, or any combination thereof, in the nasal passages, sinuses, or both of the subject.

The present application relates to the field of microbial technology, and particularly relates to a bacillus megaterium YBZ13 for preventing and treating walnut leaf scorching and application thereof. The bacillus megaterium YBZ13 is preserved in the China General Microbiological Culture Collection Center, and the preservation number is CGMCC No.28098. The bacillus megaterium YBZ13 is a walnut rhizosphere symbiotic bacterium, and the bacterial suspension has a significant prevention and treatment effect on walnut seedling leaf scorching.

The invention belongs to the technical field of application of microorganisms, and particularly relates to a strain of streptomyces endogenus WA10-1-8 in intestinal tracts of cockroaches and application of a metabolic secondary product streptopherol compound of the streptomyces endogenus WA10-1-8 in anti-MRSA (Methicillin Resistant Staphylococcus Aureus) drugs. The cockroach intestinal endophytic streptomyces WA10-1-8 provided by the invention has the taxonomic name of Streptomyces albovinaceus, is preserved in Guangdong Microbial Culture Collection Center on June 13, 2024, and has the preservation number of GDMCC No: 4.422; the streptomyces WA10-1-8 is a symbiotic bacterium which is separated and screened from intestinal tracts of insect cockroaches; a metabolic secondary product, namely a streptophezine compound, has a relatively strong inhibition effect on MRSA (Methicillin-Resistant Staphylococcus Aureus), and can be used for preparing a medicine for treating MRSA infection.

The invention discloses a flora-friendly selective antifungal peptide HRI and application thereof, and belongs to the technical field of novel antibacterial materials. The antifungal peptide HRI provided by the invention can only selectively resist pathogenic fungi instead of bacteria and especially does not resist symbiotic bacteria on the premise of maintaining flora balance, has relatively high biological safety, and has a certain inhibition effect on matrix metalloproteinase (MMP-9).

The invention discloses an entomopathogenic nematode symbiotic bacterium and an application of the entomopathogenic nematode symbiotic bacterium in prevention and control of potato pests. The symbiotic bacterium is derived from heterorhabditis bacteroides HL6. The invention further discloses a preparation method of the entomopathogenic nematode symbiotic bacterium. Researches show that the symbiotic bacterium has obvious pathogenic and lethal activity on a plurality of important potato pests, and especially has an efficient insecticidal effect on underground pests grubs and potato tuber moths which are seriously damaged by storage and fields. The symbiotic bacteria or the fermentation product thereof can quickly cause death of pests by infecting insect body cavities, destroying tissue structures and inhibiting immune response. Compared with a traditional chemical pesticide, the entomopathogenic nematode symbiotic bacterium has the advantages of being natural in source, high in safety, environmentally friendly, not prone to generating resistance and the like, is suitable for preparing a biological prevention and control preparation and is used for green prevention and control of pests in the potato production process. The invention provides a new biological prevention and control resource and technical approach for sustainable prevention and control of potato pests, and has good application prospect and popularization value.

The application discloses a corynebacterium striatum phage and application thereof. The corynebacterium striatum phage is a corynebacterium striatum phage CSP1, the preservation number of which is CGMCC NO: 45598, and the preservation time is July 4, 2023. The corynebacterium striatum phage has strong tolerance, biological safety and carries site-specific recombination functional elements (integrase and recombination sites). Meanwhile, the corynebacterium striatum phage can lyse 20 strains of multi-drug resistant corynebacterium striatum, and lays a foundation for subsequent medical researches using the corynebacterium striatum phage as a test and treatment carrier, a targeted pathogenic bacterium or symbiotic bacterium, and an immune regulator inducer.

A genetically modified strain of commensal bacteria Staphylococcus epidermidis is provided which produces a material with UV absorbing properties. The material with UV absorbing properties may be a mycosporine-like amino acid such as shinorine.

The invention provides application of lactobacillus plantarum YMJK-001 in fermented plant beverages and traditional Chinese medicines, and belongs to the technical field of functional microorganism fermentation and application. The lactobacillus plantarum YMJK-001 is obtained through self-screening, the preservation number of the lactobacillus plantarum YMJK-001 is CGMCC No.36695, a heat-resistant symbiotic bacterium system needing to be inactivated at the temperature of 100 DEG C for 60 minutes is formed when the lactobacillus plantarum YMJK-001 is subjected to symbiotic fermentation with lactobacillus casei ATCC393 and lactobacillus acidophilus ATCC4356, and the heat-resistant symbiotic bacterium system needs to be inactivated at the temperature of 100 DEG C for 60 minutes; the mixed bacterium retains high activity and does not need an embedding process. Meanwhile, the feed additive has extremely high transformation capacity on traditional Chinese medicine and plant beverages, debitterizing, sweetening and flavor reconstitution are realized, and the palatability is remarkably improved without addition. By applying a fermentation system containing the strain, the process can be simplified, the production cost can be reduced, the commercialization path of functional fermented drinks can be expanded, and the method has extremely high popularization value.

A genetically modified strain of commensal bacteria Staphylococcus epidermidis is provided which produces a material with UV absorbing properties. The material with UV absorbing properties may be a mycosporine-like amino acid such as shinorine.

The application discloses a friendly-bacterial flora type selective antifungal peptide HRI and application thereof, and belongs to the technical field of antibacterial new materials. The antifungal peptide HRI can selectively resist pathogenic fungi but not bacteria, especially not symbiotic bacteria, under the premise of maintaining bacterial flora balance, has high biological safety, and has a certain inhibitory effect on matrix metalloproteinase (MMP-9).