The invention relates to a substituted pyrrole chromone compound, which adopts the following structure: R1, R2, R3 and R4 are selected from hydrogen, halogen, C1-3 alkyl, C1-3 substituted alkyl, alkoxy, acyl, a carboxylic acid group, carboxylate radical, a nitrogen group, a phosphorous group or a sulfur group; R5 is selected from a substituted or non-substituted cyclic group; and R6 is selected from hydrogen or C1-3 alkyl, acyl, carboxylic acid group, carboxylate radical group, nitrogen group, phosphorous group or sulfur group. A type-5 phosphodiesterase inhibitor can be used for preparing medicine for curing diseases related to type-5 phosphodiesterase and is particularly suitable for preparing medicine for cuing male sexual dysfunction or pulmonary hypertension diseases.