The invention relates to the technical field of
photodynamic therapy, in particular to a synthesis method of an
algae integrated
oxygen supply platform based on
OLED photoelectric shielding material modification, and the method comprises the following steps: step 1, selecting a photoelectric material based on pentaperylene
diimide (PPD), including PPD derivatives modified by PPD-Se, PPD-Te and PPD-Br and containing heavy atoms as a core
photosensitizer; step 2, mixing a photoelectric material based on PPD, a PEG derivative containing PPD-Se and a responsive
chemical bond, and DSPE-PEG-S-S-NHH through a
coprecipitation method, and stirring for 1-6 hours at the temperature of 30-70 DEG C to form PPD type photoelectric material nano-particles with the particle size within the range of 80-120 nm, namely PPD-based NPs; step three, pretreatment and compounding of
green algae:
chlorella,
scenedesmus and
chlamydomonas are used as
oxygen supply carriers, the surface of the
green algae is modified through
carboxymethyl chitosan CMCS, and carboxyl groups are introduced; and step 4, combining the modified PPD type photoelectric material nano particles with the microalgae through amido bonds, so as to form the microalgae-photoelectric material composite
system Alga (at) PPD-based.