127 results about "Active matter" patented technology

The invention discloses a preparation method and application of anti-photoaging collagen polypeptide. The preparation method comprises the following steps: unfreezing and cleaning silver carp skin, airing and cutting; naHCO3 is added, and soaking is carried out; adding Na2CO3 and carrying out ultrasonic impurity removal; performing ultrasonic-assisted treatment; adding protease for enzymolysis treatment; establishing an enzymolysis kinetic model under the alkaline protease condition; standing, cooling and centrifuging the enzymatic hydrolysate, collecting supernate, filtering, and performing vacuum freeze drying to obtain faint yellow SCSCP; the light aging resistant peptide SCSCP02 is separated, and the active peptide sequences of the light aging resistant peptide SCSCP02 are GPPGPPGTPGPQ, SGLPGPIGPPGPR and GLPGPIGPPGPR. The active substances which are extracted from the fish skin and have the anti-photoaging effect can reduce the risk of skin light damage caused by UVR by acting on various treatment targets, resource waste can be reduced, environmental pollution caused by biological resources can be relieved, and sustainable development of the industry can be promoted.

The invention relates to a multi-active particle size gradient multilayer dry-method thick electrode and a preparation method thereof, the structure of the dry-method thick electrode comprises a current collector, the current collector is provided with a first surface and a second surface which are oppositely arranged along the thickness direction, the first surface and the second surface are sequentially provided with a plurality of layers of dry-method electrode diaphragms from inside to outside, and the dry-method electrode diaphragms are arranged on the first surface and the second surface. The particle sizes of active substances in each layer of diaphragm of the multi-layer dry-method electrode diaphragm are different; the preparation method has the advantages that the electron / ion conductivity of the pole piece is improved, and the rate capability of the pole piece can also be improved.

The invention provides a composite nanoparticle with active substance sequential release capability, a multifunctional microneedle patch based on curcumin-loaded ZIF-67 nanoparticles, preparation methods of the composite nanoparticle and the multifunctional microneedle patch and application of the multifunctional microneedle patch, and belongs to the technical field of biology. The composite nano-particles with the active substance sequential release capability are CurZIF-67NPs, the average particle size is 403 + / -7 nm, the microstructure is dodecahedral structure particles with rough textures on the surface, and the composite nano-particles have the effects of slowly releasing bioactive substances, improving the inflammatory microenvironment and regulating and controlling osteogenesis under certain conditions. The composite nano-particle comprises curcumin powder and a ZIF-67 nano-material, the ZIF-67 nano-material can be decomposed to quickly release Co < 2 + >, macrophages are regulated and controlled to be polarized to an M2 type, and excessive immune inflammation reaction is improved; the curcumin powder is slowly released, so that the periodontal ligament stem cells can be regulated and controlled to be differentiated into osteoblasts, and the osteogenic activity is enhanced.

The invention provides kelp fucoidin with low molecular weight and high anti-anaphylaxis as well as a preparation method and application thereof, and belongs to the technical field of food processing. The preparation method comprises the following steps: mixing kelp fucoidin with water to obtain a kelp fucoidin solution; and mixing the kelp fucoidin solution with H2O2 and Vc, reacting, adjusting the pH value, dialyzing and freeze-drying to obtain the kelp fucoidin with low molecular weight and high anti-allergic property. The H2O2-Vc degradation system is innovatively applied to preparation of the low-molecular-weight kelp fucoidin and improvement of the anti-allergic activity of the low-molecular-weight kelp fucoidin. In the degradation process, the chemical composition of the fucoidin is partially changed, but monosaccharide types and functional groups are not influenced. Through multiple ways of cell model and animal model experiments, the degraded laminaria fucoidin is more prominent in anti-allergic activity. Technical support is provided for development of seaweed-derived anti-allergic functional active substances, and high-valued utilization of kelp resources in the fields of functional food and medicines is further promoted.

The invention discloses a rhodotorula mucilaginosa strain as well as a fermentation product filtrate and a biological product thereof, and belongs to the technical field of microorganisms. The rhodotorula mucilaginosa BTN-HB-L28 strain is separated and purified from meconopsis in Lijiang of Yunnan, can be used in the field of cosmetics, has the effects of resisting skin oxidation, resisting aging, repairing skin and relieving skin, can be used as an active matter in skin care products, and has practical application value. The fermentation product filtrate of the strain has excellent HAS inhibition ability, and can significantly inhibit the expression of matrix metalloproteinase 3; the fibroblast proliferation can be obviously promoted under various concentrations; the proportion of SA-beta-Gal positive cells can be remarkably reduced under various concentrations, and the anti-aging effect is achieved; the antioxidant composition has remarkable DPPH and ABTS free radical scavenging capacity and has a good antioxidant effect; the secretion amount of cell inflammatory factors NO, IL-6 and TNF-alpha can be remarkably inhibited, and the good relieving effect is achieved.

The invention discloses a method for screening an active matter for protecting skin cell telomeres, and relates to the technical field of biotechnology and cosmetic development, and the method is technically characterized by comprising the following steps: a) providing stem cells derived from an exosome which carries at least one microRNA for regulating and controlling a telomere protection factor CTC1; b) acting a candidate active matter on the stem cells, and separating to obtain a treated exosome; the technical effects are as follows: the combination of miR-150-5p and miR-181c is delivered through the exosome, the dual-miRNA coordinated regulation is realized, the limitation of the traditional single-target detection is broken through, the CD63 / CD81 protein on the membrane surface of the exosome can be specifically combined with the skin cell membrane, and the Franz diffusion experiment verifies that the micro-fluidic chip integrates the collagen scaffold and the dynamic shear force.

The present disclosure provides lipid nanoparticles having a sphere like structure, compositions comprising the lipid nanoparticles and methods for delivery of the agents. The lipid nanoparticles have improved properties for delivery of biologically active agents, such as RNA.

A system and method for removing a target substance in a surface or subsurface water flow includes an enclosure formed by a geotextile wrapping material, and a filling composition contained in the enclosure. The filling composition includes an amount of active material dispersed in a media material, where the active material is capable of binding, absorbing or otherwise reacting to the target substance to thereby reducing the amount of the target substance from the resulting water flow exiting the system.

A preparation method and an application for an oil-in-water nanoemulsion material are provided, the method is a new method combining sonication-phase inversion composition-phase inversion temperature, S-PIC-T method, i.e., the combined application of the sonication, the phase inversion composition method and the phase inversion temperature develops a new type nano-preparation with small droplet size, high loading hydrophobic small molecule substances, and stable physical and chemical properties. Therefore, in the present disclosure, the sonication in the high-energy method is combined with PIC and PIT in the low-energy method, because the sonication does not produce high heat, the amount of surfactant is reduced, and the size of emulsion droplets is reduced while the energy consumption is low, while PIC and PIT reduce production costs and protect the biological activity of hydrophobic bioactive substances.

The invention discloses a method for extracting a natural antioxidant from a cyperus esculentus shell fermentation product by using subcritical water, and belongs to the technical field of plant antioxidant extraction. The preparation method comprises the following steps: fermenting cyperus esculentus shell powder to obtain fermentation liquor; performing subcritical water extraction on the fermentation liquor to obtain an extracting solution; and filtering, purifying and freeze-drying the extracting solution to obtain the natural antioxidant. The plant cell walls can be selectively and mildly degraded and deconstructed by utilizing rich enzyme systems secreted by specific microorganisms in the growth and metabolism process. The biological pretreatment not only can destroy the physical barrier of the cell wall, but also can release active substances in a combined state in the cell wall, so that the active substances are converted into a free state, and the dissolution efficiency and the yield of subsequent extraction are greatly improved. Subcritical water extraction has the outstanding advantages of high extraction efficiency, high speed, no need or great reduction of the use amount of organic solvents, environmental friendliness and the like.

The invention relates to the field of plant extracts, in particular to a torreya grandis total RNA extract which at least comprises mRNA, tRNA, miRNA and tsRNA. The torreya grandis total RNA extract can be used as a natural active matter for an external preparation for the skin, and the effects of resisting oxidation, resisting aging or resisting wrinkles and tightening are achieved, so that the skin aging is delayed.

The capsule may be exposed to an alternating magnetic field to release the active material, and may include a core containing the active material and a shell surrounding the core, at least one of the core and the shell may include at least one induction heating element particle heated by exposure to the alternating magnetic field.

The invention discloses a polysaccharide aldehyde modification method based on a plasma technology, relates to the technical field of biological material modification, and aims to solve the problems of environmental pollution, harsh reaction conditions and complex product purification in the conventional chemical oxidation method. Comprising the following steps: S1, preparing a polysaccharide solution; dissolving polysaccharide in a solvent, and stirring until the polysaccharide is completely dissolved to obtain a homogeneous polysaccharide solution; and S2, plasma in-situ oxidation treatment. In an inert gas atmosphere environment, plasma is generated by using a coaxial dielectric barrier discharge device, and active substances of the plasma directly act on a polysaccharide solution, so that an aldehyde group is introduced to a polysaccharide molecular chain, and an aldehyde polysaccharide solution is obtained. And S3, freeze-drying and forming. And freeze-drying the obtained aldehyde polysaccharide solution to obtain the aldehyde polysaccharide solid material with the three-dimensional porous network structure. The method is simple and convenient to operate, easy to popularize, simple in equipment, short in process, free of complex purification steps and beneficial to laboratory and large-scale production and application.

To provide a technique for delivering an active substance to the surface of a target cell.SOLUTION: According to one embodiment, a particle-bound lipid particle includes a biodegradable lipid particle, a particle, and active substances, wherein the particle is bound to an outer surface of the lipid particle, and the active substances are bound to a surface of the particle.SELECTED DRAWING: Figure 1

Methods of forming patterned features on a surface of a substrate are disclosed. Exemplary methods include gas-phase formation of a layer comprising an oxalate compound on a surface of the substrate. Portions of the layer comprising the oxalate compound can be exposed to radiation or active species that form exposed and unexposed portions. Material can be selectively deposed onto the exposed or the unexposed portions.

A method and system of adaptive cold atmospheric based treatment for diseased tissues, such as an area with cancerous cells, is disclosed. A gas such as helium is ionized via supplying power between and anode and a cathode to create an initial cold atmospheric plasma jet. The initial plasma jet is directed toward the area for a sufficient time, such as 10 seconds, to sensitize the cells via a reactive species. A reactive treatment, such as H2O2 or TMZ, is directed to the sensitized cells. The effectiveness of the reactive treatment is increased by the process of sensitizing the cells.

Presented are processes for the beneficial conversion of CO2 and other environmentally destructive compounds to their constituent parts by the application of thermal plasma containing activated species whereby the interaction of the plasma with the compounds and reactions of CO2 and H2 generate more environmentally friendly compounds comprising in part oxygen and hydrogen. The thermal plasma may be vibro-shear plasma generated by the superheating of either steam, gas or a combination of both.

A method for filling a gap in a substrate is disclosed. The method includes providing a substrate with a gap in a reaction chamber, forming first active species from a first reactant to create an inhibition layer near the top of the gap, and performing one or more deposition cycles to deposit material into the gap. Each deposition cycle involves introducing a second reactant to form a chemisorbed layer and generating a second active species from a third reactant using pulsed plasma power, which reacts with the chemisorbed layer to form a deposited layer. The inhibition layer partially inhibits deposition at the top of the gap. The deposited material comprises silicon nitride, which is subsequently converted to silicon oxide by providing a fourth reactant containing hydrogen and oxygen. This conversion results in volume expansion and improved gap filling.

To provide compositions and methods for mediating EPS. [Solution] This disclosure relates to a method for inhibiting the stability of a biofilm, comprising contacting the biofilm with an effective amount of an active substance that interferes with the binding of polyamines to DNA in the biofilm. Also provided herein is a method for treating a biofilm in a subject, comprising administering an effective amount of an active substance that interferes with the binding of polyamines to DNA in the biofilm to a subject infected with a biofilm. Further described herein is a method for treating a biofilm in a patient with systemic lupus erythematosus (SLE) and / or cystic fibrosis (CF), comprising administering an effective amount of an active substance that interferes with the conversion of B-DNA to Z-DNA in the biofilm or its local environment.

The present invention relates to a magnetic fish scale-based biochar and a preparation method thereof, as well as its application in degrading antibiotic wastewater. Cheap discarded fish scales are used as raw materials, which are modified by decalcification, crushing, and activation using an activator transition metal acetate. After freeze-drying, the pore structure is optimized by high-temperature pyrolysis to form a multi-activation site catalyst with surface-loaded bimetallic nanoparticles. The rapid electron transfer effect between carbon and transition metals is utilized to produce a large amount of active substances, thereby obtaining magnetic fish scale-based biochar with a high specific surface area and high saturation magnetization. The preparation method has simple and easy steps, low raw material cost, short production cycle, easy control of production process conditions, conventional equipment required, strong practicality and operability, and can be promoted and applied in large-scale industry. The application of the modified magnetic fish scale-based biochar in the treatment of antibiotic wastewater can effectively remove antibiotics in water and reduce the toxicity of wastewater.

To provide electrochemically mediated gas capture, including from low concentration streams.SOLUTION: Methods, apparatuses, and systems related to the electrochemical separation of target gases from gas mixtures are provided. In some cases, a target gas such as carbon dioxide is captured and released as needed using an electrochemical cell (for example, by bonding to an electroactive species in a reduced state). Some embodiments are particularly useful for selectively capturing the target gas with little to no reaction with oxygen gas that may be present in the gas mixture. Some such embodiments may be useful in applications involving separations from gas mixtures having relatively low concentrations of the target gas, such as direct air capture and ventilated air treatment.SELECTED DRAWING: None

The invention relates to the technical field of cyanobacterial bloom treatment, and discloses a composite slow-release algal-inhibiting colloid and a preparation method and application thereof.The composite slow-release algal-inhibiting colloid comprises phenolic acid algal-inhibiting active substances, chitosan, polyvinylpyrrolidone and lactic acid, the average hydrodynamic particle size of the composite slow-release algal-inhibiting colloid is 50-800 nm, and the average hydrodynamic particle size of the composite slow-release algal-inhibiting colloid is 100-200 nm. The phenolic acid algal inhibition active substance is selected from one or more of gallic acid, pyrogallic acid and p-hydroxybenzoic acid. Targeted enrichment of algae is achieved through the electrostatic adsorption effect between positive charges of a chitosan molecular chain and negative charges on the surface of cyanobacteria cells; meanwhile, a three-dimensional network structure jointly constructed by the chitosan and the polyvinylpyrrolidone wraps the active substances, long-acting slow release is achieved, the colloid has the dual functions of targeted adsorption and long-acting slow release, and the utilization efficiency and action durability of the algal inhibition active substances are improved.

To provide methods, apparatuses, and systems related to electrochemical capture of Lewis acid gases.SOLUTION: Methods, apparatuses, and systems related to electrochemical capture of Lewis acid gases from fluid mixtures are generally described. Certain embodiments are related to electrochemical methods involving selectively removing a first Lewis acid gas from a fluid mixture containing multiple types of Lewis acid gases (e.g., a first Lewis acid gas and a second Lewis acid gas). Certain embodiments are related to electrochemical systems comprising certain types of electro active species having certain redox states in which the species is capable of binding a first Lewis acid gas but for which binding with a second Lewis acid gas is thermodynamically and / or kinetically unfavorable. The methods, apparatuses, and systems described herein may be useful in carbon capture and pollution mitigation applications.SELECTED DRAWING: None

The present application relates to an electrode suitable for use in electrochemical sensing of a target species. The electrode comprises a peptide monolayer of defined length and to one end of which are attached both a redox active species and a receptor that is capable of binding to the target species. Also provided is an electrochemical method of sensing a target species, which involves the use of the electrode.

The invention provides a subject-object interface assembled double-ligand MOF and PVA mixed matrix membrane, which is prepared by the following steps: jointly dissolving metal salt and amino acid in deionized water, carrying out ultrasonic treatment, adding a solubilizer, carrying out ultrasonic treatment, adding an active substance, carrying out ultrasonic treatment, carrying out hydrothermal reaction on the obtained mixture at 60-100 DEG C for 1-3 hours, centrifuging to take a solid, and drying to obtain the subject-object interface assembled double-ligand MOF and PVA mixed matrix membrane. Washing with ethanol, and drying to obtain a subject-object interface assembled double-ligand MOF (Metal Organic Framework); dispersing the film-forming matrix in deionized water, and performing water bath at 60-100 DEG C for 1-3 hours to obtain a film-forming matrix solution; adding the host-guest interface assembled double-ligand MOF into the film-forming matrix solution, uniformly stirring to obtain a film-forming solution, carrying out tape casting on the film-forming solution, and drying to obtain a host-guest interface assembled double-ligand MOF (at) PVA mixed matrix film; the preservative is safe and non-toxic, has good hydrophobic property, barrier property and remarkable antibacterial property, and lays a solid and reliable foundation for deep research in the field of preservation.

The invention relates to a method for reducing the density of microorganisms in a usable space of a device, the method comprising heating the usable space to a process temperature such that the relative humidity in the usable space is below an upper humidity value; adjusting the relative humidity in the usable space to a first target value for a first duration, wherein a humidification system introduces an active substance; stopping the adjustment of the relative humidity; and degrading the active substance in the usable space for a degradation duration. The invention also relates to a corresponding device and a corresponding system.