1386results about How to "Promote migration" patented technology

The invention provides temperature and pH responsive hydrogel entrapped with chlorogenic acid lipidosome as well as a preparation method and application of the temperature and pH responsive hydrogel, and relates to the technical field of biology. The temperature and pH responsive hydrogel entrapping chlorogenic acid lipidosome contains chlorogenic acid lipidosome, phenylboronic acid grafted modified gelatin and dopamine grafted oxidized hyaluronic acid, the concentration of the phenylboronic acid grafted modified gelatin is 3-10 wt%, the concentration of the dopamine grafted oxidized hyaluronic acid is 3-10 wt%, and the concentration of chlorogenic acid is 1-20 [mu] M. The temperature and pH responsive hydrogel can effectively promote wound healing independently or in combination with blue light.

The invention relates to the technical field of computer code upgrading, and discloses an automatic code upgrading method and device based on a compiler and a storage medium. The method comprises the steps that firstly, lexical analysis, grammatical analysis and semantic analysis are conducted on a source code, an abstract syntax tree is generated, then a new standard grammatical rule mapping table is constructed, and a new standard grammatical rule mapping table is generated; and traversing the abstract syntax tree, querying whether the nodes of the abstract syntax tree can be queried in the mapping table, outputting the character strings mapped to the queried nodes, and normally outputting codes conforming to node semantics for the nodes which are not queried. The abstract syntax tree of the original code is automatically traversed, and node matching and conversion are performed according to the syntax rule mapping table of the new standard, so that the need of manual intervention is greatly reduced, the automation degree of code migration from an old standard to the new standard is improved, a large amount of manpower and time cost is saved, and the migration problem caused by human errors is reduced.

The invention discloses a recombinant humanized XVII type collagen as well as an expression vector and a genetically engineered bacterium thereof. Four functional fragments with high activity are obtained through screening, one of the fragments is optimized and then combined according to a certain sequence to obtain recombinant humanized XVII type collagen JYC1703, or one of the fragments is optimized and then combined according to a certain sequence, and GPP sequences are fused at an amino terminal and a carboxyl terminal respectively to obtain recombinant humanized XVII type collagen JYC1701 and JYC1702, and the recombinant humanized XVII type collagen JYC1701 and JYC1702 are combined according to a certain sequence to obtain the recombinant humanized XVII type collagen JYC1701 and JYC1702. After codon optimization, amplifying and cloning into an expression vector, transforming into pichia pastoris competent cells after enzyme digestion linearization, and screening high-copy recombinants through G418 resistance gradient, so as to obtain pichia pastoris genetically engineered bacteria for expressing recombinant humanized XVII type collagen. The recombinant humanized XVII type collagen JYC1701, JYC1702 and JYC1703 disclosed by the invention show excellent functions of promoting cell adhesion, cell proliferation and cell migration, and are suitable for preparing products such as skin care products or medical instruments and the like.

The invention belongs to the technical field of preparation of microorganisms and cosmetics, and particularly relates to a strain composition, radix paeoniae rubra fermentation liquor prepared from the strain composition and application of the strain composition in cosmetics. Specifically, Pseudoalteromonas sp. SE9 and Schizoscharomyces pombe JM2-16 are utilized to perform fermentation treatment on radix paeoniae rubra root powder, and the finally obtained radix paeoniae rubra fermentation liquor has multiple effects of resisting oxidation, promoting proliferation and migration of keratinocytes, promoting skin injury repair, resisting allergy, resisting inflammation, relieving and the like, is high in safety, can be used as a cosmetic component, and can be used as a cosmetic preparation. Therefore, the method has good practical application value.

The invention relates to a cross-domain cold start article recommendation method based on triple contrast learning. The method comprises the following steps of: performing biased processing on article attribute information and knowledge graph information in a source domain and a target domain to obtain initial attribute representation and initial graph representation, and acquiring initial user representation from interaction information of a user and the article in the source domain by utilizing a multi-thermal coding method; obtaining the screened attribute representation by using a multi-layer perceptron, and obtaining the aggregated map representation by using a map attention network; on the basis of current attribute representation, graph representation and interaction information, a recommendation result is obtained through a trained cross-domain cold-start item recommendation model, and the model is constructed and optimized through a self-comparison learning loss function, a source domain comparison learning loss function, a cross-domain comparison learning loss function and a BPR loss function in a joint training mode. Compared with the prior art, the method has the advantages of fully utilizing hot article collaboration information, reducing field difference, improving article content characterization quality and the like.

The invention relates to a progressive knowledge distillation lightweight method, device and equipment based on a pruning network. The method comprises the steps of obtaining an original model, a preset pruning layer number and a training sample in a target task scene; pruning a first layer of the original model according to a preset pruning proportion, taking the original model as a teacher model, taking the pruned model as a student model, training the teacher model and the student model by adopting a distillation training strategy according to the training sample, and determining a first lightweight model, and pruning the next layer on the basis of obtaining the lightweight model after pruning, and repeating the training steps until the number of pruned layers meets a set value. According to the method, the concept of progressive pruning is adopted, pruning is carried out gradually from the shallow layer of the model, learning is carried out based on the provided middle characteristic distillation loss and output distillation loss, knowledge in an original model can be better migrated, and therefore the precision loss of an inference result caused by model lightweight is avoided to the maximum extent.

The invention relates to the technical field of optical disk storage, in particular to an optical disk box storage management system based on hierarchical management, which comprises a data analysis module, a weight calculation module, a strategy making module, a medium selection module, a dynamic adjustment module and a performance evaluation module. According to the method, the optical disk data is deeply analyzed, and the access frequency, the file number and the modification frequency of the data are recorded, so that the storage requirement and the change of a data access mode can be more effectively identified, the accurate recording and weight distribution of data attributes and the sensitivity analysis of optical disk files are realized, and a more detailed storage management strategy is constructed; storage positions and priorities can be adjusted according to actual use conditions of data, real-time data requirements are responded, a mechanism is adjusted in real time to improve response speed and operation efficiency of a system, continuous adaptability and efficiency of a storage strategy are ensured through regular performance evaluation, and reliability and safety of long-term data storage are guaranteed.

The invention discloses a preparation method of antistatic modified chinlon filaments, and relates to the field of chinlon filaments. When the antistatic modified chinlon filament is prepared, (formylmethyl) diethyl phosphate and 1-aminopyrrole react to prepare pyrrole diethyl phosphate; reacting the hydroxylated multi-walled carbon nanotube with pyrrole diethyl phosphate to obtain a modified multi-walled carbon nanotube; the preparation method comprises the following steps: reacting 2, 2 '-bipyridine-5, 5'-dicarboxylic acid with 2-amino-5-nitrophenol, and then reducing to obtain a benzoxazole diamine monomer; then, adipic acid, 1, 5-diaminopentane and a benzoxazole diamine monomer are subjected to a reaction, and modified polyamide is prepared; uniformly mixing the modified polyamide, the modified multi-walled carbon nanotubes, pyrrole, ferric trichloride and copper chloride, and performing melt spinning to obtain the antistatic modified polyamide filament. The antistatic modified chinlon filament prepared by the invention has excellent antistatic, flame-retardant, anti-aging and mechanical properties.

The invention discloses a Br-COFs material and a preparation method thereof as well as a preparation method of a covalent organic framework material interface film of a lithium metal battery. The preparation method comprises the following steps: dissolving 1, 3, 5-tri (4-aminophenyl) benzene and 2, 5-dibromobenzene-1, 4-dicarboxaldehyde in an organic solvent, dropwise adding acetic acid into the solution, reacting the reaction mixture under stirring, filtering, washing and drying to obtain the covalent organic framework material; and dissolving the obtained Br-COFs material and a PVdF adhesive in an organic solvent to obtain a mixed solution, coating the surface of a copper foil with the mixed solution according to a certain thickness, and forming the Br-COFs artificial interfacial film on the surface of a copper foil electrode after the solvent is volatilized. The preparation method is simple, the preparation process is green and environment-friendly, and the prepared product is high in purity, controllable in structure and high in mechanical strength, can be directly used as an artificial interface film of a lithium metal battery, and shows excellent stability when being used for a Li / Cu battery.

The invention requests to protect a rolling bearing fault diagnosis method based on envelope spectrum knowledge distillation. The method comprises the following steps: obtaining a rolling bearing vibration signal, and carrying out sample division and normalization processing; the spectral kurtosis of the source working condition sample is calculated, the center frequency and bandwidth of envelope demodulation are determined according to the spectral kurtosis, envelope demodulation is carried out, and the demodulation sample is sent to a teacher network phi for pre-training; respectively inputting an original vibration sample and an envelope spectrum sample under a source working condition into a student network psi and a pre-trained teacher network phi, and extracting bearing health state representations learned by the two networks to establish envelope spectrum knowledge distillation loss; calculating the prediction loss of the student network, the cross-working-condition sample probability distribution alignment loss and the diversity loss represented by the health state; carrying out multi-loss back propagation, and optimizing the weight and bias of the fault diagnosis network by adopting an Adam optimizer; and finally, inputting the target working condition sample into the trained fault diagnosis model for performance testing.

The invention relates to the field of cell biology, and particularly discloses an exosome as well as a preparation method and application thereof. The method for preparing the exosome comprises the following steps: (1) introducing nucleotide sequences for coding a signal peptide TPA and an epidermal growth factor into an AAVS1 region of a host cell, such as a sequence shown in SEQ ID No.9 and a sequence shown in SEQ ID No.10, so as to obtain a modified host cell; and (2) collecting the exosome secreted by the modified host cell. The expression level of EGF mRNA in the exosome can be remarkably improved, so that the obtained exosome has a better effect in skin wound treatment.

The invention relates to the technical field of cellular immunotherapy, in particular to application of efonidipine in preparation of a dendritic cell immunologic adjuvant. The invention provides an application of efonidipine in preparation of a dendritic cell immunologic adjuvant. It is found that efonidipine can promote maturation, migration and antigen presentation functions of DCs, and the homing ability of DCs and CD8 + T cell activation are remarkably improved. The activation aspect of efonidipine on DCs comprises improvement of expression of maturation indexes CD80, CD40 and CD86, expression of a migration index CCR7, activation of CD8 + T cells by antigen presentation and the like. The efonidipine used in the invention is a drug approved by FDA for clinical treatment of cardiovascular diseases, the application of the efonidipine in immunotherapy is found, new use of old drugs is realized, and the efonidipine has great economic value.

The invention relates to the technical field of fibers, and discloses an antibacterial and antistatic fiber material based on silver ions and halamine and a preparation method of the antibacterial and antistatic fiber material. The preparation method comprises the following steps: loading a methyl methacrylate-based polymer on the surface of a silver-loaded molecular sieve through an in-situ polymerization method, and grafting a halamine antibacterial monomer chlorinated piperidinol through an ester exchange reaction to obtain an antibacterial agent; the preparation method comprises the following steps: carrying out reaction polymerization on caprolactam, quaternized polyether, polyethylene glycol, 2, 6-dipicolinic acid and adipic acid to obtain an antistatic agent; an antibacterial agent, an antistatic agent and nano-silver are added into chemical fiber slices, the antibacterial and antistatic fiber material based on silver ions and halamine is prepared after melt spinning, and the chemical fiber slices are polyester slices or chinlon slices or polypropylene slices. The fiber material has excellent antibacterial and antistatic properties.

The invention provides a novel human-derived II-type collagen COLII-14K-H and a coding gene thereof, the coding gene is shown as SEQ ID NO.1, and the amino acid sequence is shown as SEQ ID NO.2. The invention further provides a preparation method of the novel human-derived II-type collagen COLII-14K-H. The invention also provides a preparation method of the human-derived II-type collagen COLII-14K-H and application of the human-derived II-type collagen COLII-14K-H in preparation of cartilage repair drugs, skin repair drugs and skin care products. The inventor-derived II-type collagen can obviously improve the gene expression level of the collagen, so that the content of the collagen in human dermal fibroblasts is improved, and the skin aging is delayed; meanwhile, the protein fragment can show a remarkable skin repairing effect at low concentration, provides a new treatment choice for skin repairing, and can be widely applied to the fields of skin repairing and nursing.

The invention discloses a preparation method of a zinc-dihydromyricetin nano-enzyme and application of the zinc-dihydromyricetin nano-enzyme in preparation of drugs for promoting healing of diabetic wounds, and the zinc-dihydromyricetin metal polyphenol nano-enzyme (Zn-DHM) is obtained by coordinating a metal element zinc (Zn) and a natural product dihydromyricetin (DHM) through a one-step method by taking PVP as a surfactant. The Zn-DHM nano-enzyme prepared by the invention has antioxidant property and cell proliferation and migration promoting ability, and can maintain metabolism and immune homeostasis of diabetic wounds, so that the Zn-DHM nano-enzyme can accelerate early healing of the diabetic wounds.

The invention belongs to the field of lithium ion batteries. The invention provides an electrode plate and a lithium ion battery containing the same, an active layer of the electrode plate comprises a first layer and a second layer, the first layer is arranged close to a current collector, the second layer is arranged on one side, far away from the current collector, of the first layer, the mass percentage content of a binder of the first layer is greater than that of the second layer, and the mass percentage content of the binder of the second layer is less than that of the first layer. The adhesive is redistributed, so that release force and cohesiveness are guaranteed, migration of the adhesive can be improved, influence of migration of the adhesive on uniformity and conductivity is reduced, and electrical properties such as manufacturability and energy density of the electrode plate are improved. And the method is very suitable for the adaptation of the lithium manganese iron phosphate positive electrode with small particle size and large specific surface area and the battery thereof.

The invention belongs to the field of organic electroluminescence, and discloses an electron transport layer material and a preparation method and application thereof. The structure of the material of the electron transport layer is as shown in a chemical formula I: # imgabs0 #. The compound of the material of the electron transport layer provided by the invention is composed of 9-alkyl-9-phenylfluorenyl, a triazine group and cyano-substituted aryl or heteroaryl, and the groups have high electron affinity to form an efficient electron transport channel; the organic light-emitting material also has good thermal stability, and as an electron transport layer material of an organic electroluminescent device, the organic light-emitting material has the characteristics of low driving voltage, high luminous efficiency and long service life.

The invention discloses multifunctional hydrogel for promoting healing of diabetic wounds and a preparation method of the multifunctional hydrogel. The multifunctional hydrogel is prepared from Ti3C2Tx-Ag, paeoniflorin (PF), a gel matrix oxidized konjac glucomannan (OKGM) solution and carboxymethyl chitosan (CMCS). The method comprises the following steps: mixing Ti3C2Tx powder with AgNO3 in deionized water, heating to boiling, adding a proper amount of a sodium citrate solution, reacting to obtain Ti3C2Tx-Ag (TA) powder, and mixing the powder with a paeoniflorin (PF) and oxidized konjac glucomannan (OKGM) solution and a carboxymethyl chitosan (CMCS) solution to prepare the KC-PF-TA hydrogel. The multifunctional hydrogel has excellent photo-thermal antibacterial performance, anti-inflammatory performance and angiogenesis promoting performance, shows a remarkable effect of promoting healing of diabetic wounds through the synergistic effect of Ti3C2Tx-Ag and paeoniflorin, and has good biocompatibility; the multifunctional nano-composite hydrogel disclosed by the invention has great application prospect and value in the field of wound repair materials.

The invention provides a staged release type rigid-flexible composite nerve conduit as well as a preparation method and application thereof. A polymer fiber membrane with a double-layer nanofiber membrane structure is used as a tube wall, multi-section hydrogel comprising short-section hydrogel containing anti-inflammatory substances and long-section hydrogel containing growth factors is used as an inner core, and bioactive substance particles containing the growth factors are deposited on the inner wall of the polymer fiber membrane. The staged release type rigid-flexible composite nerve conduit is obtained. The composite nerve conduit provided by the invention is a rigid-flexible composite nerve conduit capable of controllably delivering anti-inflammatory substances and growth factors in time and space to meet the requirements of each stage of injury, and is combined with multiple induction signals such as a topological structure, chemotactic induction and the like to regulate and control the microenvironment of each stage after spinal cord injury and promote subsequent functional recovery.

The invention discloses a high-activity chemical copper plating solution and a chemical copper plating method, and relates to the technical field of chemical copper plating, and the chemical copper plating solution comprises the following components: a copper ion source, a biological enzyme, a natural polymer complexing agent, a pH regulator and a stabilizer; according to the method, the specific bio-enzyme is adopted as the chemical copper plating catalyst, the remarkable catalytic effect is shown, the bio-enzyme has efficient selectivity and catalytic activity, reduction and deposition of copper ions can be accelerated under the mild condition, and therefore reaction energy consumption and equipment requirements are reduced, meanwhile, use of chemical reagents is reduced, and the cost is reduced. In addition, natural polymer complexing agents such as chitosan and sodium alginate have good biocompatibility and degradability and can form a stable complex with copper ions, the stability and the copper plating effect of the plating solution are enhanced, and by designing the natural polymer complexing agent with a specific structure such as a hyperbranched structure, the copper plating effect of the plating solution is improved. And the complexing ability and the performance of the copper plating solution are further improved.

The invention belongs to the technical field of biological medicines, and particularly relates to an application of a Pucurbita pepo polypeptide Nacrein-LP20 in preparation of a medicine for promoting wound healing and a preparation method of the Pucurbita pepo polypeptide Nacrein-LP20. The amino acid sequence of the Hepu pearl polypeptide Nacrein-LP20 is as shown in SEQ ID NO: 1 (Sequence Identity Number 1). According to the present invention, the Pucurbita pepo active polypeptide Nacrein-LP20 has characteristics of strong DPPH free radical and hydroxyl free radical removing ability and excellent antioxidant activity, can significantly promote HaCaT cell proliferation in the high glucose environment, and can promote migration and repair of HaCaT cells in the high glucose environment; the traditional Chinese medicine composition has a remarkable healing promoting effect on full-cortical resection wound surfaces of normal rats and diabetic rats.

The invention provides an application of a recombinant XVII type humanized collagen or a composition containing the recombinant XVII type humanized collagen in preparation of a preparation for preventing and / or treating lupus erythematosus, which can overcome the defect that more adverse reactions are generated in treatment in the existing scheme.

The invention provides a preparation method of a laminated cell, the laminated cell and a photovoltaic module, and can be widely applied to the photovoltaic technical field, the preparation method of the laminated cell comprises the following steps: providing a bottom cell, and forming a composite layer on the bottom cell; a first transmission layer is formed on the composite layer, and a skeleton layer is formed on the first transmission layer through double-source evaporation; wherein a first evaporation source of the double-source evaporation comprises inorganic cesium salt, and a second evaporation source of the double-source evaporation comprises inorganic lead salt and inorganic rubidium salt; coating organic salt on the framework layer to form a perovskite layer; forming a second transmission layer and an electrode on the perovskite layer to obtain a laminated cell; wherein carriers of the first transmission layer and the second transmission layer are different. The framework layer is formed through double-source evaporation, the proportion is better controlled, through rubidium and lead, a positive effect can be generated on crystallization, stress release and the like of perovskite in the crystallization process, part of rubidium salt can be combined with PbI2 decomposed on the surface, ion migration is reduced, and the device stability is improved.

The invention discloses an acne grading method, system and equipment based on multi-modal fusion and a medium, belongs to facial acne severity grading in the technical field of artificial intelligence, and aims to solve the technical problem of poor facial acne severity grading effect in the prior art. A constructed facial acne grading model comprises a VGG feature extraction module, a multi-modal feature fusion module, an acne feature sensing module and a comprehensive grading module, the VGG feature extraction module extracts facial features in different modals, and the multi-modal feature fusion module models the relation between the facial features in different modals through cross attention for fusion. The acne feature sensing module enhances the sensing of acne features through a cross attention mechanism, and the comprehensive grading module makes a comprehensive and accurate acne severity grading result. According to the method, comprehensive grading of the severity of the acnes is realized by combining the multi-modal face pictures of the patient, and the grading effect of the severity of the facial acnes is greatly improved.

The invention relates to an in-situ osteochondral regeneration and repair scaffold and a preparation method thereof, the in-situ osteochondral regeneration and repair scaffold prepared by the method comprises a cartilage layer, a connecting layer and a subchondral bone layer, the porosity of the cartilage layer is not less than 85%, the Young modulus is 6-13KPa, and the aperture is 130-140 [mu] m; the porosity of the connecting layer is not lower than 95%, the Young modulus is 4-19 KPa, and the aperture is 50-120 [mu] m; the porosity of the subchondral bone layer is not lower than 95%, the Young modulus is 4-19 KPa, and the aperture is 300-400 microns. The in-situ osteochondral regeneration and repair scaffold prepared by the method has good biocompatibility, is beneficial to attachment, migration and proliferation of cartilage cells and bone marrow mesenchymal stem cells, does not cause immunological rejection, provides a better scaffold environment for repair after osteochondral implantation, and has a good application prospect in the field of in-situ osteochondral regeneration and repair, and experiments prove that the in-situ osteochondral regeneration and repair scaffold has a good application prospect in the field of in-situ osteochondral regeneration and repair. The in-situ osteochondral regeneration and repair scaffold does not affect cell migration; animal experiments prove that the in-situ osteochondral regeneration and repair scaffold has a good repair effect on rat osteochondral defects.

The invention discloses a method for leaching rare earth elements in neodymium iron boron waste through synergistic reinforcement of sulfating roasting and a surfactant, and belongs to the technical field of rare earth recovery. The method comprises the following steps: mixing neodymium iron boron waste and concentrated sulfuric acid to prepare a roasting raw material; carrying out roasting treatment on the roasted raw material to obtain a roasted product; the roasted product and a leaching agent are mixed and then leached and filtered, filter residues and filtrate are prepared, and the filtrate is directly used for separation of rare earth elements leached from the neodymium iron boron waste; the leaching agent at least comprises two surfactants. According to the method provided by the invention, multiple surfactants are compounded and cooperate with the sulfating roasting process, so that the leaching rate of the rare earth can be effectively improved, the acid consumption can be reduced, and the purpose of improving the recovery purity of the rare earth element can be achieved; in addition, the compound surfactant is simple in preparation method and convenient to use, and the neodymium iron boron waste recovery cost is reduced to a large extent.

The invention relates to the technical field of molecular biology diagnosis, in particular to application of an FIBCD1 marker. The invention provides an application of a substance for inhibiting expression of an FIBCD1 marker in preparation of a medicine for preventing and / or treating breast cancer complicated with diabetes mellitus. The invention also discloses application of a reagent for detecting expression of the FIBCD1 marker in preparation of a kit for diagnosis and / or prognosis evaluation of breast cancer combined with diabetes mellitus. According to the application, a novel cancer-promoting regulation molecule FIBCD1 is found, and through experimental analysis, the FIBCD1 is abnormally highly expressed in focus tissues of a BC-DM patient and is positively correlated with the fasting blood-glucose value of the patient, so that a novel target is provided for precise prevention and treatment and targeted intervention of the unique breast cancer subtype BC-DM.

The invention discloses a lithium-free negative electrode for a lithium metal battery, a preparation method of the lithium-free negative electrode and the lithium metal battery. The lithium-free negative electrode comprises a current collector, the metal layer is arranged on at least one side of the current collector, and the material of the metal layer is one or more of tin, magnesium, zinc, bismuth, lead, silver and aluminum; and the graphene oxide layer is arranged on one side, far away from the current collector, of the metal layer. According to the invention, the deposition uniformity of lithium at the negative electrode is improved to inhibit the growth of lithium dendrites, and the coulombic efficiency and the capacity retention ratio of the battery are improved.

The preparation method comprises the following steps: preparing PET non-woven fabric raw paper, preparing a nano-zinc oxide particle dispersion liquid, dipping the PET non-woven fabric raw paper in a solution, carrying out heat treatment to form a functional PET non-woven fabric, preparing a functional alkenyl ionic liquid, carrying out heat treatment to form a PET non-woven fabric, and carrying out heat treatment to form the PET reinforced bi-crosslinked polyionic liquid composite solid electrolyte. Adding a cross-linking agent, a lithium salt, a plasticizer and a photoinitiator to prepare an electrolyte precursor solution; the functional PET non-woven fabric is placed in the electrolyte precursor solution, standing and dipping are carried out under the vacuum condition, then thermal polymerization and photopolymerization are carried out, and the solid electrolyte is prepared and applied to the solid polymer lithium ion battery; the zinc oxide particles are compounded into the PET non-woven fabric to form the non-woven fabric which is thin in thickness, high in tensile strength and appropriate in porosity, and the non-woven fabric is cross-linked with the functionalized alkenyl ionic liquid and the electrolyte precursor solution step by step, so that the ionic conductivity, the electrochemical window and the thermal stability of the solid electrolyte and the safety performance of the battery in use are improved.

The invention discloses a lithium battery organic-inorganic composite flame-retardant diaphragm which comprises a base material diaphragm and a flame-retardant layer on the outer side of the base material diaphragm, the base material diaphragm is a polyolefin diaphragm, and the flame-retardant layer is prepared from benzoxazine resin particles, natural clay mineral nanotubes and auxiliaries; the mass ratio of the benzoxazine resin particles to the natural clay mineral nanotubes is (40%-95%): (5%-60%). According to the present invention, the design is novel, the thermal stability and the flame retardant property of the polyolefin diaphragm in the lithium battery are effectively improved, the affinity of the polyolefin diaphragm to the electrolyte is improved, and the safety of the battery monomer is substantially improved.