The invention relates to a Chinese medicinal composition for treating chronic myeloid leukemia, which consists of the following components: 15 to 25 grams of rehmanniae praeparatum, 8 to 16 grams of tree peony bark, 18 to 28 grams of honey-fried extract glycyrrhiza, 18 to 32 grams of spreading hedyotis herb, 14 to 20 grams of lalang grass rhizome, 18 to 28 grams of glossy privet fruit, 14 to 28 grams of desertliving cistanche, 4 to 8 grams of cordyceps sinensis, 12 to 20 grams of Indian iphigenia bulb, 8 to 16 grams of stiff silkworm and 8 to 16 grams of eupolyphaga. The Chinese medicinal composition can carry out pertinence treatment on chronic myeloid leukemia, selectively inhibits and kills immature cells, induces apoptosis of leukemia cells, has strong pertinence and better treatment effect, promotes differentiation and maturation of leukemia cells, regulates qi and blood, strengthens the immunity, promotes recovery of the normal hematopoietic function of bone marrow, reduces reversion, prevents tolerance from being generated, reduces the toxic or side effects of chemotherapy and strengthens physical fitness.