34results about How to "Safe and efficient preparation" patented technology

A unit heats water to a specified temperature and then alerts a user or automatically mixes the heated water with dry baby formula and dispenses the mixture into a baby bottle.

The invention discloses a DC cell and a targeting immune cell population, and a preparation method and application thereof. The preparation method of DC cells includes the steps of: conducting first induced differentiation culture on mononuclear cells in order to obtain immature DC cells; transfecting the immature DC cells by using HSV-2 antigen mRNA, so as to obtain transfected immature DC cells; and conducting second induced differentiation culture on the transfected immature DC cells, so as to obtain mature DC cells, wherein the mononuclear cells are isolated from mononuclear cells of peripheral blood of a sample. The method can prepare DC cells safely and efficiently, has a low cost and high efficiency, and can effectively solve the problem of cytotoxicity. The method can be effectively used for immune cell treatment or stimulation of lymphocytes derived from a same patient to produce a targeting cell population containing a large amount of CTL cells, and then the cell population can be used for virus infection immunotherapy to reach better effect.

The invention provides a sulfide solid electrolyte, a preparation method thereof and an all-solid-state battery. The chemical formula of the solid electrolyte is Li6PS5Cl1-x (BH4)x, and the preparation method comprises the following steps: uniformly mixing Li2S, LiCl, LiBH4 and P2S5 in proportion to obtain a mixture; placing the mixture in a ball milling tank for ball milling; and tabletting the ball-milled sample, and sintering to obtain the sulfide solid electrolyte. According to the sulfide solid electrolyte disclosed by the invention, a BH4 <-> anion group is introduced into the solid electrolyte to replace a part of Cl <-> sites, so that a larger transmission channel is provided; and the conduction of Li < + > is promoted by the unique rotary motion of the BH4 <-> anion group, and after the BH4 <-> anion group is introduced, the ionic conductivity of the electrolyte is greatly improved on the basis of a lithium-argyrodite electrolyte Li6PS5Cl.

The invention relates to a naphthoxy mono-metallocene transition metal compound, a catalyst composition containing the naphthoxy mono-metallocene transition metal compound, and application of the catalyst composition. The naphthoxy mono-metallocene transition metal compound structurally contains naphthoxy, a Cp' ligand and a transition metal, and thenaphthoxy group and the Cp' ligand are respectively connected with the transition metal to form the naphthoxy mono-metallocene transition metal compound. The catalyst composition comprises the naphthoxy mono-metallocene transition metal compound and alkylaluminoxane, and can be used in a polymerization catalyst for olefin polymerization, wherein in the polymerization system, the concentration of the mono-metallocene transition metal compound in the polymerization system is 1*10<-8>-1*10<-3> mol/L. The naphthoxy mono-metallocene transition metal compound is simple to prepare, and when the catalyst composition containing the naphthoxy mono-metallocene transition metal compound is used for olefin polymerization, a polymer with high molecular weight and narrow molecular weight distribution can be obtained.

The invention discloses a rotary kiln selenium distillation system which comprises a steel main platform, a slurrying charging system, a sulphating roasting rotary kiln, a selenium absorption system and a production line control system, wherein the slurrying charging system, the sulphating roasting rotary kiln, the selenium absorption system and the production line control system are all arranged on the steel main platform; the slurrying charging system is connected with the left end of the sulphating roasting rotary kiln; the selenium absorption system is connected with the sulphating roasting rotary kiln and comprises a vacuumizing device, a waste heat recovery and smoke discharge system and a selenium absorption device; the sulphating roasting rotary kiln comprises a rotary kiln body and a fuel gas heating system; and a kiln head gas guide pipe is arranged at the upper end of the rotary kiln body and is connected with the selenium absorption device. According to the system disclosed by the invention, large-scale industrial production of selenium products can be realized, and the system has the advantages of high efficiency, high safety and slight pollution.

The invention discloses a DC cell and a targeting immune cell population, and a preparation method and application thereof. The preparation method of DC cells includes the steps of: conducting first induced differentiation culture on mononuclear cells in order to obtain immature DC cells; transfecting the immature DC cells by using CEA antigen mRNA, so as to obtain transfected immature DC cells; and conducting second induced differentiation culture on the transfected immature DC cells, so as to obtain mature DC cells, wherein the mononuclear cells are isolated from mononuclear cells of peripheral blood of a sample. The method can prepare DC cells safely and efficiently, has a low cost and high efficiency, and can effectively solve the problem of cytotoxicity. The method can be effectively used for immune cell treatment or stimulation of lymphocytes derived from a same patient to produce a targeting cell population containing a large amount of CTL cells, and then the cell population can be used for tumor immunotherapy to reach better effect.

The invention provides rotary screen printing white ink and a preparation method thereof. The rotary screen printing white ink comprises the components in parts by mass: 15-30 parts of a polyurethane acrylate oligomer, 3-10 parts of an ultraviolet initiator, 40-55 parts of titanium dioxide, 5-10 parts of dipentaerythritol hexaacrylate, 10-20 parts of hexanediol diacrylate, 0.5-1 part of a dispersing agent, 0.5-2 parts of a leveling agent, 0.2-2 parts of an antifoaming agent and 0.1-0.5 part of a polymerization inhibitor, wherein the polyurethane acrylate oligomer comprises a bifunctional polyurethane acrylate oligomer and a hexafunctional polyurethane acrylate oligomer; and the defoaming agent is selected from one or more of a polyether defoaming agent, an amine defoaming agent and an amide defoaming agent. The rotary screen printing white ink shows a satisfactory printing effect when performing field printing and character printing at the same time, and has excellent and balanced drying speed and adhesion at the same time.

The invention relates to a method of Computed Tomography imaging comprising: a. Performing a single acquisition of image data from at least two contrast agents into a blood vessel network, a first contrast agent among said at least two contrast agents having been in said blood vessel network for a longer time than a second contrast agent among said at least two contrast agents, b. Processing said image data using K-Edge detection and/or iodine delineation to separate data associated with each contrast agents in order to obtain a concentration map of each contrast agent, c. Determining from said image data a first part of the blood vessel network comprising both the first contrast agent and the second contrast agent, and a second part of the blood vessel network comprising only the first contrast agent, d. Calculating a partial blood volume map of the first part of the blood vessel network based on the total amount of second contrast agent and on the concentration map of the second contrast agent, e. Calculating a partial blood volume map of the second part of the blood vessel network based on the total amount of first contrast agent, on the concentration map of the first contrast agent and on the partial blood volume map of the first part of the blood vessel network.

The invention belongs to the technical field of metal additive manufacturing, and particularly relates to nickel-based alloy powder and a preparation method and application thereof. The nickel-based alloy powder is used as a coating layer to coat composite ceramic reinforced particles. The nickel-based alloy powder with the structure can effectively solve the thermal cracking tendency of the original nickel-based alloy powder in the printing process, and solves the problems that the added ceramic particle heterogeneous nucleating agent cannot be uniformly and stably distributed on the nickel-based alloy powder and cannot meet the large-scale production requirement.

The invention discloses a DC cell based on HBV1 antigen, a targeting immune cell population, a preparation method and applications thereof. The preparation method of the DC cell comprises the following steps: subjecting mononuclear cells to first induced differentiation culture to obtain immature DC cells; transfecting the immature DC cells by HBV1 antigen mRNA to obtain transfected immature DC cells; subjecting the transfected immature DC cell to second induced differentiation culture to obtain mature DC cells; wherein the mononuclear cells are separated from peripheral blood mononuclear cells of a sample. Through the provided preparation method, the DC cells can be obtained efficiently and safely. Moreover, the provided preparation method has the advantages of low cost and high efficiency, and can effectively solve the problem of cell toxicity. The DC cells can be applied to cell immunotherapy or used to trigger the lymph cells from the same patient to generate targeting immune cell population rich in CTL cells so as to achieve a better effect in tumor immunotherapy.

The invention discloses a DC cell based on SURVIVIN antigen, a targeting immune cell population, a preparation method and applications thereof. The preparation method of DC cell comprises the following steps: subjecting mononuclear cells to first induced differentiation culture to obtain immature DC cells; transfecting the immature DC cells by SURVIVIN antigen mRNA to obtain transfected immature DC cells; subjecting the transfected immature DC cell to second induced differentiation culture to obtain mature DC cells; wherein the mononuclear cells are separated from peripheral blood mononuclear cells of a sample. Through the provided preparation method, DC cells can be obtained efficiently and safely. Moreover, the provided preparation method has the advantages of low cost and high efficiency, and can effectively solve the problem of cell toxicity. The DC cells can be applied to cell immunotherapy or used to trigger the lymph cells from the same patient to generate targeting immune cell population rich in CTL cells so as to achieve a better effect in tumor immunotherapy.

The invention discloses a DC cell based on HPVE6 antigen, a targeting immune cell population, a preparation method and applications thereof. The preparation method of DC cell comprises the following steps: subjecting mononuclear cells to first induced differentiation culture to obtain immature DC cells; transfecting the immature DC cells by HPVE6 antigen mRNA to obtain transfected immature DC cells; subjecting the transfected immature DC cell to second induced differentiation culture to obtain mature DC cells; wherein the mononuclear cells are separated from peripheral blood mononuclear cells of a sample. Through the provided preparation method, the DC cells can be obtained efficiently and safely. Moreover, the provided preparation method has the advantages of low cost and high efficiency, and can effectively solve the problem of cell toxicity. The DC cells can be applied to cell immunotherapy or used to trigger the lymph cells from the same patient to generate targeting immune cell population rich in CTL cells so as to achieve a better effect in tumor immunotherapy.

The invention discloses continuous self-cleaning glass substrate growth equipment which comprises a feeding and receiving transition cabin mechanism, an air cylinder pushing mechanism, a quartz tube,a first heating furnace, a second heating furnace and an equipment frame. The quartz tube is cylindrical and is fixedly arranged on the equipment frame; the feeding and receiving transition cabin mechanism comprises a discharging cabin, a receiving cabin and a quartz tube; the bottoms of the two ends of the quartz tube are fixedly connected with the equipment frame through supporting frames. The wall portion of one end of the quartz tube is communicated with a discharging bin through a flange, a first gate valve is arranged at the joint of the flange, a first air cylinder is arranged at the end of the discharging bin, and the first air cylinder is connected with a first push rod extending into a cavity of the discharging bin. The equipment is an innovative invention developed on the basisof a carbon dioxide etching method, has the characteristics of simplicity, mildness, low cost and releasability through the carbon dioxide etching method, and is very suitable for large-area and low-cost batch preparation of the ultra-clean graphene film.

The invention discloses a DC cell based on HM1.24 antigen, a targeting immune cell population, a preparation method and applications thereof. The preparation method of DC cell comprises the following steps: subjecting mononuclear cells to first induced differentiation culture to obtain immature DC cells; transfecting the immature DC cells by HM1.24 antigen mRNA to obtain transfected immature DC cells; subjecting the transfected immature DC cell to second induced differentiation culture to obtain mature DC cells; wherein the mononuclear cells are separated from peripheral blood mononuclear cells of a sample. Through the provided preparation method, DC cells can be obtained efficiently and safely. Moreover, the provided preparation method has the advantages of low cost and high efficiency, and can effectively solve the problem of cell toxicity. The DC cells can be applied to cell immunotherapy or used to trigger the lymph cells from the same patient to generate targeting immune cell population rich in CTL cells so as to achieve a better effect in tumor immunotherapy.

The invention discloses a DC cell based on HPVE7 antigen, a targeting immune cell population, a preparation method and applications thereof. The preparation method of DC cell comprises the following steps: subjecting mononuclear cells to first induced differentiation culture to obtain immature DC cells; transfecting the immature DC cells by HPVE7 antigen mRNA to obtain transfected immature DC cells; subjecting the transfected immature DC cell to second induced differentiation culture to obtain mature DC cells; wherein the mononuclear cells are separated from peripheral blood mononuclear cells of a sample. Through the provided preparation method, DC cells can be obtained efficiently and safely. Moreover, the provided preparation method has the advantages of low cost and high efficiency, and can effectively solve the problem of cell toxicity. The DC cells can be applied to cell immunotherapy or used to trigger the lymph cells from the same patient to generate targeting immune cell population rich in CTL cells so as to achieve a better effect in tumor immunotherapy.