249 results about "Brain development" patented technology

Disclosed are infant formulas comprising fat, protein, carbohydrate, vitamins, and minerals, including on an as-fed basis, at least about 5 mg / L of gangliosides, at least about 150 mg / L of phospholipids, at least about 70 mg / L of total sialic acid with at least about 2.5% as lipid-bound sialic acid, at least about 0.13% docosahexaenoic acid by weight of total fatty acids, and at least about 0.25% arachidonic acid by weight of total fatty acids. Also disclosed are methods of accelerating brain development, neural migration, and cognitive development in an infant by administering the infant formulas during the first 2-4 months of life, preferably as a sole source of nutrition.

The present invention relates to the field of education of human subjects, and more specifically to a computer program for training the brain development disorder where in human subjects are impaired of social interaction and communication. The program deliver animated content to the subject and varies the size, clarity, colors, background images, animated characters, sound with animation, method of instructions, so they would be more easily distinguished by the subject and thereby gradually improves the subject's neurological processing and memory of the elements through repetitive stimulation. Thus the system, method and apparatus of the present invention maximizes the effectiveness and efficiency of learning by adding a reward delivery system to deliver the object of the student's interest upon achieving the goal set by the trainer. The system includes modules configuration system, user validation system, content delivery system, user response / input system, monitoring system and feedback system. The configuration engine includes a progress module which monitors a user's performance on any of learn, review and test modules and changes the future lessons based on the monitored performance. The content delivery system includes help or instructions screen to provide assistance with any of the learning lessons.

The invention discloses a virtual realistic intelligent projection gesture interaction all-in-one machine. The virtual realistic intelligent projection gesture interaction all-in-one machine comprises a microcomputer, a 3D object and human body motion detection device connected to the microcomputer and a projection device. The 3D object and human body motion detection device is used for sensing objects, recognizing three-dimensional objects and gestures and inputting reorganization signals into the microcomputer. The projection device is used for displaying content to be displayed by the microcomputer. The all-in-one machine is arranged on a wall, can sense three-dimensional motion of a hand, a finger and a pen, 2.5D motion of the finger and the pen on the plane (wall) and three-dimensional motion of other objects, achieves virtual and realistic integration through projection and interaction of the hand and the pen and displayed 2D interface and interaction of 3D virtual objects, can run a variety of software in a terminal and overcomes the deficiency that display devices of televisions and screens are harmful to eyes and lack of man and machine interaction and accordingly affects brain development due to the two-dimensional display in a traditional teaching process.

The invention relates to balanced-nutrition healthy edible blend oil with brain tonic efficacy. The balanced-nutrition healthy edible blend oil is prepared by adopting vegetable fat as a main raw material and adding seaweed oil which occupies 0.02-0.9 percent by weight of the edible blend oil. The edible blend oil contains omega-6 polyunsaturated fatty acid and omega-3 polyunsaturated fatty acid in a weight ratio of 4:1 to 6:1 and also comprises an additive of antioxidant which occupies 0-0.2 percent by weight of the edible blend oil. The invention has the advantages that the blend oil has balanced proportion of fatty acid, reasonable proportion of polyunsaturated fatty acid, natural anti-oxidation efficacy to human bodies and healthcare functions of promoting brain development and preventing diseases, such as cardiovascular diseases, and the like, improves the oxidation stability of the blend oil and reduces the fishy smell after the seaweed oil is added.

The present invention relates to a nutritional composition, in particular directed to children of 3-6 years, said nutritional composition comprising a protein source, a source of available carbohydrates, a lipid source, at least one probiotic microorganism, and prebiotics, wherein said lipid source comprises DHA (docosahexaenoic acid) and / or ARA (arachidonic acid). The nutritional composition improves cognitive performance, in particular memory, learning comprehension, alertness, attention, concentration, processing speed, conceptual thinking, abstract thinking, verbal abilities, language comprehension, psychomotor skills, curiosity, and confident interaction with the environment. Preferably, the composition comprises one, a combination of several or all selected of the group of DHA, ARA, LA, ALA, choline, iron, iodine and folic acid.

The nonlinear complexity of EEG signals is believed to reflect the scale-free architecture of the neural networks in the brain. Analysis of the complexity and synchronization of EEG signals as described herein provides a quantitative measure for routine monitoring of functional brain development in infants and young children and provide a useful biomarker for detecting functional abnormalities in the brain before the cognitive, behavioral or social manifestations of these brain developments can be observed and measured by standard tests. One or more machine learning algorithms are used to discover relevant patterns in the complexity and synchronization values determined from the EEG data to facilitate risk assessment and / or diagnosis of developmental disorders in infants and young children by predicting cognitive, behavioral and social outcomes of the measured functional brain activity patterns.

The invention provides nutritional blend oil containing fish oil or polyene fish oil. The blend oil adopts refined peanut oil, double-low rapeseed oil and other plant oil as raw material, fish oil and polyene fish oil is taken as mixing oil, and antioxidant agent consists of lipo-soluble tea polyphenol and vitamin E. Addition is calculated according to physical and nutritional requirement of various population and the content of various fatty acid in raw oil and mixing oil. Every 100g of product blend oil contains SFA 12-18g, MUFA 39-46g, omega-6 PUFA 31-38g and omega-3 PUFA 5-9g, wherein, total amount of omega-3 LCPUFA DHA+DPA+EPA is 0.1-5.0g, the ratio of DHA and (DPA+EPA) is 0.25-10:1, and the ratio of DHA and EPA is 4:1-25:1. The blend oil has the effect of promoting brain development, preventing myopia and early-aged dementia and reducing the occurrence of cardiovascular and cerebrovascular diseases, etc.

The invention relates to a stable preparation of phosphatidylserine and a preparation method, application as well as an application product of the stable preparation. The preparation method comprises the following step of processing the phosphatidylserine through microencapsulation, micro-pelletization or liposome encapsulation. The stable preparation of the phosphatidylserine can be independently applied as a medicine or can be added into daily foods, drinks and health-care products, also has an important effect on health care of brains while guaranteeing the color and the taste of the daily foods and the drinks of people and is of great benefit to brain disorder such as nutritional supplement of brain development of students, overstrain of nerves of the adults, and memory loss, brain atrophy and senile dementia of the middle aged and elderly people.

The invention provides a neural fingerprint extraction and classification method. The method comprises an image acquisition step, a brain structure annotation step and a neural fingerprint extractionstep in sequence. The method has the advantages that information mining is performed on magnetic resonance images in different sequences, a unified fingerprint extraction and establishment method forall brain areas is formed through unified structure annotation establishment and positioning, a comprehensive neural fingerprint system is constructed, neural fingerprint standard libraries for different sexes and different ages are established, and therefore brain health assessment, disease classification and parting and disease prediction can be performed on a to-be-tested target; through the establishment of the neural fingerprint standard libraries, quantitative assessment and classification can be performed on brain development, brain senescence, neural diseases and mental diseases of a to-be-tested object, and talent assessment, advantage assessment, senescence assessment, rehabilitation assessment, assistant diagnosis, disease prediction and other technologies can be formed; and a standard technical foundation is laid for advantage cultivation, brain healthcare and diagnosis and prevention of brain diseases of human talents.

A method for assessing brain age based on neural images relates to the field of brain age prediction. There is a shortage of an effective, reliable and sensitive technology in the process of extracting brain aging characteristics based on neural images. The method specifically comprises the following steps: step 1, establishing a neural image data set; step 2, performing neural image preprocessing; step 3, extracting features; 4, performing feature pooling and dimension reduction; and 5, carrying out feature selection and model construction. According to the method, the degree of deviation from the average development track in the human brain development process is evaluated, and noninvasive and universal early warning evaluation is provided for brain development.

The invention discloses a compound type fish scale and shaddock ped jelly and a processing method thereof. The compound type fish scale is characterized by comprising 20-40 percent by weight of fish scale boilout filtrate, 20-40 percent by weight of white shaddock ped filtrate, 5-15 percent by weight of yellow shaddock ped filtrate, 4-8 percent by weight of sugar, 0.60-1.0 percent by weight of carrageenin, 0.3-0.7 percent by weight of potassium sorbate and the balance of water. Compared with the prior art, the compound type fish scale and shaddock ped jelly has the advantages of fully utilizing beneficial ingredients of fish scale and shaddock ped and being attracted in flavor and being favored by old people and children. In addition, the compound type fish scale and shaddock ped jelly has health care functions of promoting the brain development of children, improving memory, reducing serum total cholesterol and triglyceride, moistening skin, resisting crease, and the like.

The invention relates to a production method for a yoghourt containing a flaxseed superfine powder. The production method comprises the following steps: (1) carrying out raw material treatment; (2) adding brown powdered sugar in skim milk and uniformly stirring; (3) heating the milk by a pasteurization method and preserving heat; (4) fermenting to obtain an intermediate product; (5) cooling the intermediate product and adding the flaxseed superfine powder, then uniformly stirring and mixing through a homogenizer, cooling and refrigerating, thereby obtaining the yoghourt containing the flaxseed superfine powder. The production method disclosed by the invention has the following beneficial effects that 1, efficient absorption for the effective ingredients of flaxseeds is benefited; 2, the flaxseed gum contained in the flaxseeds is capable of playing the role of a stabilizer, and other stabilizers do not need to be added; 3, by adding the flaxseed superfine powder in the yoghourt, the contents of omega-3 polyunsaturated fatty acids and dietary fibres in the yoghourt can be increased, brain development is benefited, eyesight is protected, a regulation role is played on immunosuppression, and blood fats are reduced.

This application discusses systems and method for entraining oromotor pattern development, such as the suck, in the orofacial system of an infant having neurological impairments or developmental disabilities. The system includes a baglet, an entrainment device, and a processor. In varying examples, the system additionally includes one or a combination of: a baglet pressure sensor, a memory, a timing circuit, a valve, a receiver assembly, a display device, and one or more data acquisition, data analysis, and stimulus-control software. Options and variations for each feature of the system are various. The present systems provide patterned, rhythmic stimulation to the infant's orofacial system to stimulate and entrain brain development, such as oromotor pattern development.

Disclosed are nutritional formulas generally, and infant formulas specifically, including a combination of RRR-alpha tocopherol, LC-PUFAs, and optionally vitamin C. The combination enhances brain development and improves cognitive performance in an individual, and specifically in an infant.

The invention discloses a probiotics-containing breast milk-like formula milk powder for infants. Raw milk is used as a base material; according to nutrient differences of breast milk and raw milk, whey protein is added to adjust the ratio of whey protein to casein in a product to be close to 6:4; soybean oil is added to adjust deficiency of linoleic acid in milk fat, wherein linoleic acid accounts for about 12.8 percent of the total fat of the breast milk but only 2.2 percent of the total fat of raw milk; arachidonic acid (AA), docosahexaenoic acid (DHA), sialic acid (SA) and 3'-sialyllactose(3'-SL) are added to promote brain development of infants and improve memory and intelligence; and bifidobacterium lactis HN019, bifidobacterium animal Bb-12 and lactobacillus paracasei N1115 are added to regulate intestinal healthy development of infants. The invention also provides a preparation method of the milk powder. The milk powder is close to the nutrition index in the Chinese breast milk and is suitable for growth and development of infants in China.

The present invention relates to a nutritional composition, in particular directed to toddlers and / or a weaning child, said nutritional composition comprising a protein source, a source of available carbohydrates, a lipid source, at least one probiotic microorganism, and prebiotics, wherein said lipid source comprises DHA (docosahexaenoic acid). The nutritional composition improves cognitive performance, in particular learning and memory of the child. Preferably, the composition comprises sphingomyelin, sialic acid, choline, essential fatty acids and taurine.

A method and apparatus for non-invasively determining a blood oxygenation level within a subject's tissue is provided. The method includes the steps of: a) providing a spectrophotometric sensor operable to transmit light into the subject's tissue, and to sense the light; b) inputting into the sensor at least one of the subject's age, weight, brain development, and head size; c) spectrophotometrically sensing the subject's tissue along a plurality of wavelengths using the sensor, and producing signal data from sensing the subject's tissue; and d) processing the signal data utilizing the at least one of the subject's age, weight, brain development, and head size, to determine the blood oxygen saturation level within the subject's tissue using a difference in attenuation between the wavelengths.

The present invention provides caregivers with pragmatic systems and methods for implementing current knowledge of early childhood brain development and for facilitating meaningful interaction with a child in their care. The invention further provides systems and methods that enable caregivers to provide a child with a stimulating environment that includes purposeful activities in a playful, interactive context.

The invention firstly aims at providing formula goat milk powder for infants. The formula goat milk powder for the infants is prepared from the following raw materials in parts by weight: degreased goat milk powder, whole goat milk powder, concentrated goat whey protein powder, gangliosides, lactose, glucose syrup solids, milk fat, OPO structure grease, docosahexaenoic acid, arachidonic acid, a vitamin premix, a mineral substance premix, taurine, vegetable oil, compound probiotics and the like. According to the formula goat milk powder for the infants, provided by the invention, brain trophic factors including the gangliosides, the milk fat, the OPO structure grease and the compound probiotics and the like are added; particularly, the synergistic effect of the gangliosides, the docosahexaenoic acid and the arachidonic acid is utilized so that functional components of the formula goat milk powder for the infants are relatively close to those of breast milk; and furthermore, the brain development of the infants is further improved. The invention secondly aims at providing a preparation method of the formula goat milk powder for the infants, and the preparation method has the characteristics of simple process steps and easiness of controlling technical parameters, and is suitable for large-scale production.

The present disclosure generally relates to nutritional compositions that are suitable for administration to adult and pediatric subjects that include a neurologic component. The neurologic component may include a flavonoid compound, such as kaempferol, fisetin, or both, and provides beneficial health benefits such as enhanced brain development and improved memory, cognition, hand-eye coordination, and enhanced focusing. Furthermore, the neurologic component may act synergistically with other brain nutrients that may be present in the compositions.

The present invention relates to an yuangboafeng (a Chinese medicinal plant) nervonic acid soft capsule and its preparation process, and provides a health-care food with the functions of preventing nerve fibre atrophy, promoting brain development, delaying senility, raising immunity of human body and digestive function. Its preparation method includes the following steps: shelling yuanbaofeng seeds, making crude oil, dewatering and filtering, low-temp. chromatography, separating saturated fatty acid to produce health-care edible oil, finally making said health-care edible oil into the soft capsule. Its nervonic acid content is stable, and its health-care function effect is good.

The invention discloses health-care soft capsules prepared by mainly taking extracts of both leaves and seeds of acer truncatum trees as raw materials and a preparation method for the health-care capsules, each capsule comprises the components of, by weight: acer truncatum leaf extract 120-160mg, acer truncatum seed extract 15-30mg, plant oil 280-320mg and vitamin E 10-20mg; The soft capsules are prepared by using both terrestrial plant acer truncatum seeds and terrestrial plant acer truncatum leaves containing respectively rich nerve acid and flavones and have functions of nerve fiber atrophy preventing, brain development promoting, anti-aging, human immunity ability enhancing and digestion promoting.

The invention discloses a health-care lozenge prepared by taking an acer truncatum extract as a major raw material and a preparation method thereof. The health-care lozenge is prepared from the following raw materials in percentage by weight: 20-40 percent of an acer truncatum extract, 15-25 percent of an acer truncatum seed extract, 30-64 percent of a seasoning agent and 1-5 percent of a nutrition fortifier. A tablet is prepared by performing deep processing on terrestrial plant acer truncatum seeds which are rich in nervonic acid and terrestrial plant acer truncatum leaves which are rich in flavone, and has the effects of preventing nerve fiber atrophy, promoting brain development, delaying ageing and enhancing the immunity and digestive function of a human body; and over-high blood fat concentration in blood can be lowered remarkably, and the occurrence probability of diseases such as certain hypertension and cardiovascular and cerebrovascular diseases, blood circulation disorder, and the like is lowered.

The invention provides nourishing cream for animals. The problems that in the prior art, the absorption effect of calcium in animal nutrition is poor, and intestinal and stomach absorption cannot be facilitated are solved. The nourishing cream for the animals comprises the following raw materials of, by weight, 8-20 parts of animal protein, 10-16 parts of xylitol, 6-10 parts of fatty acid, 8-15 parts of edible fibers, 2-3 parts of mineral components, 1-3 parts of vitamin components, 0.5-4 parts of superfine calcium powder, 1-4 parts of calcium accelerants, 0.5-2 parts of bifidus factors and 0.5-1 part of taurine. The calcium accelerants are contained in the formula, casein phosphopeptides CPP can restrain generation of calcium phosphate precipitation, thus free calcium is kept at high concentration, and passive absorption of the calcium is facilitated. The mixture of linoleic acid and alpha-linolenic acid is selected as the fatty acid, the alpha-linolenic acid can improve brain health and intelligence and has a very important function in effective improvement of brain development, the added linoleic acid is also the nutrient needed by the animals every day, the linoleic acid and the alpha-linolenic acid exist in the nourishing cream in the combined form and can well provide the needed nutrient for the animals.

The invention discloses a composition comprising at least one long chain polyunsaturated fatty acid, at least one probiotic and a mixture of oligosaccharides, said mixture containing at least one N-acetylated oligosaccharide, at least one sialylated oligosaccharide and at least one neutral oligosaccharide, for use in brain growth and / or cognitive and / or psychomotor development. This composition is particularly adapted for use in infants, notably preterm infants.

Disclosed are methods for enhancing neural function in an individual, such as an older adult. The methods include administering nutritional compositions comprising HMB to the individual. The nutritional compositions provide benefits for individuals that have or may be at risk of having cognitive decline, cognitive impairment, and neural dysfunction, typically resulting from cognitive diseases associated with neurodegenerative diseases.

The invention provides a method for studying differentially expressed proteome in brain tissues of mice chronically infected with toxoplasma gondii by an iTRAQ (Isobaric Tags For Relative And Absolute Quantitation) technology. The invention also provides a protein or polypeptide interacting with developmentally regulated brain protein and application of the protein or polypeptide. In the invention, six toxoplasma gondii proteins interacting with the developmentally regulated brain protein are found by CoIP and Pulldown experiments; and gene knockout experiments and neurobehavioral validation are further performed on TgRPS14 gene and TgH4 gene. The method for studying differentially expressed proteome in brain tissues of mice chronically infected with toxoplasma gondii provided by the invention can rapidly and effectively perform proteomics research, and is beneficial for rapidly positioning to detection targets and prevention and treatment medicine target points with a research value or a commercial application value.

The invention provides nutritional blend oil containing seal oil. The blend oil adopts refined peanut oil and sunflower seed oil and other plant oil as raw material, seal oil is taken as mixing oil, and antioxidant agent consists of lipo-soluble tea polyphenol and vitamin E. Addition is calculated according to physical and nutritional requirement of various population and the content of various fatty acid in raw oil and mixing oil. Every 100g of product blend oil contains SFA 12-18g, MUFA 39-46g, omega-6 PUFA 31-38g and omega-3 PUFA 5-9g, wherein, total amount of omega long chain polyunsaturated fatty acids (omega-3 LCPUFA) DHA+DPA+EPA is 0.1-5.0g, the ratio of DHA and (DPA+EPA) is 0.25-10:1, and the ratio of DHA and EPA is 4:1-20:1. The blend oil has the effect of promoting brain development, preventing myopia and early-aged dementia and reducing the occurrence of cardiovascular and cerebrovascular diseases, etc.

The invention discloses a preparation method of oral liquid of acer truncatum seed oil. The preparation method comprises the following steps: weighing 100-200g of acer truncatum seed oil and 50-150g of a sweetening agent according to the formula for later use; carrying out microcapsule embedding treatment on the acer truncatum seed oil; mixing the acer truncatum seed oil subjected to microcapsule embedding treatment and the sweetening agent; and adding water to quantify at 1L, filling after homogenizing and carrying out sterile packaging to prepare the oral liquid of the acer truncatum seed oil. The oral liquid is high in vitamin and nervonic acid content, suitable for promotion of brain development of the children, improvement of the intelligence level, suppression of alzheimer's disease and parkinson's disease and improvement of sequela of cerebral apoplexy; and the prepared oral liquid is suitable for patients with dysphagia and infants for taking.