The invention relates to the technical field of biologic detection of
metabolomics, in particular to an OSAHS
metabolism marker, a diagnosis model and application of the OSAHS
metabolism marker and the diagnosis model. The
metabolic marker comprises a
red blood cell metabolite and / or a
plasma metabolite; erythrocyte metabolites comprise L-
aspartic acid, D-
ribose-5-diphosphoric acid,
cadaverine, 12, 13-
epoxy octadecenoic acid, L-
arginine, N-acetylmethionine, 5-hydroxyeicosatetraenoic acid, 13-oxo-9Z, 9, 10-tetrahydroxy-9Z, 9, 10-tetrahydroxy-9Z, 9, 10-tetrahydroxy-9Z, 9, 10-tetrahydroxy-9Z, 9, 10-tetrahydroxy-9Z, 10-tetrahydroxy-9Z, the component A is one or more of 11E-
octadecadienoic acid,
inosine monophosphate,
nicotinamide, alpha-
lactose,
sphingosine, hydroxy octadecadienoyl or
glyceraldehyde-3-
phosphoric acid; the
plasma metabolite is prepared from one or more of
fumaric acid,
cadaverine, L-
aspartic acid,
malic acid,
sphingosine-1-
phosphoric acid, L-
arginine,
cysteine-S-
sulfate,
thiosulfate, gamma-glutamyl
alanine,
galacturonic acid or
vitamin B2.