190 results about "Vitamin b" patented technology

The invention relates to an oral mucosa repairing medicine and a preparation method thereof, and belongs to the technical field of medicines, the medicine comprises barnacle peptide, salivary lactobacillus, resveratrol, a biphasic adhesion matrix, hydroxyapatite, vitamin B family and other components. The preparation method comprises the following steps: sequentially carrying out enzymolysis on barnacle gooseneck by pepsin and lumbrukinase to obtain barnacle peptide. The double-phase adhesion matrix comprises a water-phase matrix, an oil-phase matrix and lecithin; the water-phase matrix contains a chondroitin sulfate-chitosan quaternary ammonium salt compound, sodium alginate and other components; the oil-phase matrix comprises sesame oil, beeswax, a polylactic acid-glycolic acid copolymer and the like. According to the invention, barnacle peptide and salivary lactobacillus are prepared by adopting a special method and are matched with resveratrol for use, so that multi-target and multi-path promotion of oral mucosa repair can be realized; the chondroitin sulfate-chitosan quaternary ammonium salt compound is prepared through electrostatic and physical embedding, the chondroitin sulfate-chitosan quaternary ammonium salt compound is matched with other components to prepare the biphasic adhesion matrix, the biocompatibility is good, the adhesion is high, and the action time of a sustained-release drug is well prolonged.

The invention discloses a cultivation material for increasing the content of B vitamins of straw mushrooms and application of the cultivation material in straw mushroom cultivation. The cultivation material is formed by mixing and fermenting the following components in percentage by weight: 52-72% of pilose antler mushroom dregs, 10-20% of rice straws, 15-25% of waste cotton and 3% of lime. The contents of vitamin B3, vitamin B5, vitamin B6 and vitamin B12 in the volvariella volvacea sporocarp cultivated by adopting the cultivation material disclosed by the invention are obviously increased, the nutritional value of the volvariella volvacea is increased, and the market competitiveness and economic benefits of products are greatly enhanced. The pilose antler mushroom residues are used for replacing part of waste cotton raw materials, the production cost is reduced, meanwhile, efficient recycling of agricultural waste is achieved, and the method is suitable for large-scale industrial production.

The invention relates to the technical field of daily chemicals, in particular to an anti-hair-loss composition and shampoo. The composition comprises a soapberry fruit extract, a cacumen biotae extract, a ginseng root extract and a peptide compound. By removing dirt, grease and dead skin cells on the scalp, the anti-hair loss shampoo is beneficial to keeping the scalp clean and preventing hair follicle blockage, so that the hair growth environment is improved. The hair conditioner contains components (such as ginseng and cacumen biotae) capable of promoting blood circulation, and provides more nutrition for hair follicles and promotes hair growth by stimulating blood flow of the hair follicles. The hair conditioner contains plant extract, vitamin B group, amino acid and other components, and can nourish hair follicles, strengthen hair roots and reduce hair loss.

The invention discloses a method for preparing a liquid fertilizer from vitamin B12 waste liquid, and relates to the field of liquid fertilizers. When the liquid fertilizer is prepared, the vitamin B12 waste liquid is filtered and then subjected to alkaline pretreatment, and solid protein and filtrate are obtained through separation; acidifying the filtrate with sulfuric acid, adding potassium hydroxide, and concentrating under reduced pressure to obtain regenerated mixed salt; carrying out flash explosion treatment on the solid protein, and carrying out enzymolysis by using trypsin and subtilisin to obtain a proteolysis solution; urea, formaldehyde and dimethyl hydrogen phosphate are mixed to prepare slow-release phosphorus-nitrogen macromolecules; and uniformly mixing the protein enzymatic hydrolysate, the regenerated mixed salt, fulvic acid, slow-release phosphorus-nitrogen macromolecules and deionized water to obtain the liquid fertilizer. The prepared liquid fertilizer has the advantages of excellent long-term effect, easy absorption and waste liquid utilization rate.

The invention discloses an application of a dendrobium extract in preparation of a medicine for treating type 2 diabetes, and mainly relates to the technical field of dendrobium. Particularly, the invention provides the dendrobium extract-containing medicine for treating the type 2 diabetes, so that the stability of components applied to the medicine for treating the type 2 diabetes in acidic, neutral and alkaline environments is improved, and the blood sugar rising amplitude is slowed down. Compared with the prior art, the medicine for treating type 2 diabetes mellitus prepared by the invention takes the dendrobium extract as a core and is matched with the synergistic emulsion, the rhizoma polygonati extract, the dogwood extract, the radix salviae miltiorrhizae extract, the bitter gourd extract, the vitamin B and the trace element chromium element; the traditional Chinese medicine composition disclosed by the invention can be used for synergistically regulating blood sugar metabolism, enhancing insulin sensitivity, improving microcirculation, stabilizing blood sugar, improving insulin resistance and lipid metabolism and enhancing immunity and cardiovascular functions, and a safe and effective medicine is provided for preventing and treating type II diabetes.

The invention belongs to the technical field of medicines and health-care products, and discloses an earthworm protein peptide polypeptide tablet with functions of dissolving thrombus and protecting blood vessels. Comprising the following components in parts by mass: 20 to 50 parts of earthworm protein peptide, 30 to 40 parts of sorbitol, 2 to 5 parts of lactose, 2 to 10 parts of freeze-dried natto powder, 2 to 10 parts of rice bran fatty alkanol, 1 to 5 parts of dunaliella salina powder, 1 to 5 parts of bovine myocardial peptide powder, 0.01 to 0.05 part of collagen peptide, 0.01 to 0.05 part of soybean peptide powder, 0.01 to 0.05 part of vitamin B6, 0.04 to 0.12 part of a compound nutrition enhancer, 1 to 5 parts of fructo-oligosaccharide, 0.01 to 0.05 part of magnesium stearate and 0.04 to 0.012 part of a compound coating agent. The earthworm protein peptide polypeptide tablet has the effects of thrombolysis and blood fat reduction, can assist in preventing thrombosis, regulating blood fat metabolism and assisting in reducing cholesterol, and has an antioxidant function.

A lamb stomach extract Vitamin B12 preparation composition composed of lamb stomach extract and Vitamin B12 is provided. The lamb stomach extract has a chymosin activity of >40 U / g and a pepsin activity of >15 U / g, and the weight ratio of the lamb stomach extract and Vitamin B12 is 100000:0.5-5, which is useful in the treatment of moderate-to-severe chronic atrophic gastritis, intestinal metaplasia reversal, and gastric cancer prevention. Lamb stomach extract and Vitamin B12 produced synergistic or synergistic effects in specific ratios.

The invention provides a method for preparing a protease beverage by fermenting cyperus esculentus powder and a product thereof. Comprising the steps of directional pretreatment, fermentation medium preparation, segmented fermentation and optional blending, specifically, directional pretreatment adopts low-temperature extrusion at the temperature of 60-70 DEG C and ultrasonic treatment at the power of 200-300 W for cooperative treatment, and the fiber structure and antinutritional factors of soybean meal are effectively broken; in the fermentation stage, lactobacillus plantarum, saccharomyces cerevisiae and bacillus coagulans composite flora are inoculated, anaerobic fermentation is performed at the temperature of 35-37 DEG C, the pH value of the system is reduced to 4.0-4.5, and then L-cysteine hydrochloride-vitamin B synergist is added for secondary fermentation in a micro-aerobic environment at the temperature of 38-40 DEG C. The fermentation process provided by the invention is simple, the treatment is convenient, the used equipment is conventional equipment in the food industry, and the method is suitable for large-scale industrial production. Meanwhile, in the prepared fermentation liquor, the protease activity is larger than or equal to 320 U / mL, the total number of viable bacteria is larger than or equal to 1.2 * 10 CFU / mL, the optimum pH of the protease is 3.8-4.8, the optimum temperature is 37-39 DEG C, the protease is highly matched with the human gastrointestinal tract environment, and the method has wide industrialization prospects.

The invention belongs to the technical field of biological medicines, and particularly relates to a nutritional composition as well as a preparation method, application and a product thereof. The nutritional composition provided by the invention consists of nicotinamide, B vitamins and a fungal polysaccharide compound, the vitamin B consists of vitamin B1, vitamin B2, vitamin B6, vitamin B12 and folic acid; the fungal polysaccharide compound is composed of a lucid ganoderma extract, a mushroom extract, an agaricus blazei murill extract, a hericium erinaceus extract, a coprinus comatus extract, a grifola frondosa extract and a cordyceps militaris extract. Western medicine source substances (nicotinamide and B vitamins) and traditional Chinese medicine source substances (fungal polysaccharide compounds) are combined, and the nutrition composition is prepared through combination of the Chinese medicine and the western medicine. The nutritional composition has remarkable effects of enhancing immunity, delaying senescence, resisting fatigue and resisting oxidation, and shows extremely wide application prospects in the field of preparation of health-care products, medicines and cosmetics.

The invention discloses an infinitesimal bio-enzyme fertilizer capable of degrading pesticide residues of crops as well as a preparation method and application of the infinitesimal bio-enzyme fertilizer, and belongs to the technical field of bio-fertilizers. The infinitesimal biological enzyme fertilizer is prepared from the following components in parts by weight: 600 to 700 parts of water, 100 to 150 parts of immobilized beneficial microorganism bacterial material, 80 to 120 parts of activated carbon, 31 to 62 parts of amino acid material, 55 to 65 parts of organic material, 35 to 50 parts of mineral material, 32 to 64 parts of enzyme-containing base material, 1 to 5 parts of vitamin B material, 1 to 2 parts of vitamin C, 5 to 10 parts of acid-base balancing agent, 1 to 2 parts of plant growth regulator and 0.1 to 0.5 part of modified nano-selenium, the modified nano-selenium is prepared from zinc selenite, potassium selenite, sodium selenite and calcium selenite through reduction modification; the immobilized beneficial microbial material is prepared by beneficial microbial fermentation, immobilization and reinforcement. The infinitesimal biological enzyme fertilizer provided by the invention can improve the pesticide degradation rate.

The invention discloses a composition and a preparation method of a single-dose vitamin B12 eye drop without a bacteriostatic agent, and the single-dose vitamin B12 eye drop without the bacteriostatic agent is prepared from vitamin B12, a buffering agent, sodium hyaluronate, edetate disodium and water for injection. According to the vitamin B12 eye drops and the preparation method thereof disclosed by the invention, the vitamin B12 eye drops are produced by adopting a totally-closed sterile filling process, and a disposable single-dose packaging container is arranged, so that the sterility of medicines is ensured, and meanwhile, the use safety, the operation convenience index and the safety performance are improved.

The present invention relates to a composition in the form of a water-in-oil emulsion, comprising: a) at least one oily continuous phase comprising at least one volatile oil chosen from volatile hydrocarbon oils, volatile silicone oils and their mixtures, and b) at least one aqueous phase dispersed in said oily phase, the amount of water being greater than or equal to 20% by weight, with respect to the total weight of the composition, and c) at least one hydrophobic film-forming polymer, and d) at least one emulsifying surfactant chosen from polyoxyalkylenated linear polydimethylmethylsiloxanes with an HLB ≤ 8.0, and e) at least 3.0% by weight of a vitamin B3 and / or one of its derivatives, with respect to the total weight of the composition, said composition not containing a water-soluble organic UV screening agent comprising at least one benzylidenecamphorsulfonic acid group nor a water-soluble organic UV screening agent comprising at least one benzoxazolesulfonic acid group.

The invention relates to the technical field of beverage processing, in particular to a corn juice compound beverage and a preparation method thereof. The feed comprises the following raw materials: corn, black rice, oat, carrots, corncob powder, orange peel, compound enzyme, beta-cyclodextrin, Arabic gum, inulin, a yeast extract, monopotassium phosphate, vitamin B and compound strains. The compound enzyme seed is prepared from the following components: alpha-amylase, pullulanase, tannase and neutral protease; the composite strain is prepared from the following components: saccharomycetes, lactobacillus plantarum and monascus purpureus. According to the corn juice composite beverage and the preparation method thereof, through multi-dimensional synergistic interaction, the beverage realizes a layering flavor with both freshness, fruity flavor and cereal sweetness and fragrance, an anti-oxidation network constructed by polyphenol, carotenoid and ferulic acid and an intestinal tract nursing effect brought by complementation of soluble-insoluble fibers form the corn juice composite beverage with functional value and sensory experience.

The present invention discloses an agricultural composition containing lecithin. Its active ingredients include component A and component B, wherein component A is lecithin and component B is a combination of one or both of vitamin B and vitamin E. Furthermore, the agricultural composition is used in combination with an additive package, wherein the active ingredients of the additive package are a combination of chitosan oligosaccharide and gamma-aminobutyric acid. Within a certain ratio range, the agricultural composition can enhance the stress resistance of crops, eliminate pesticide damage to crops, and promote crop growth.

The application belongs to the technical field of health products, and provides a growth-promoting amino butyric acid tablet and a preparation method thereof. 12 The preparation method of the amino butyric acid tablet is as follows: first, vitamin B1, vitamin B2, vitamin B6, vitamin B , vitamin D, folic acid and a first part of fillers are fully mixed and dried to obtain premix I; then, amino acids (gamma-amino butyric acid and L-lysine), the first part of premix I and a first part of binders are uniformly mixed; then, the remaining premix I is added and uniformly mixed to obtain premix II; then, calcium citrate, magnesium oxide, ferrous fumarate and sodium selenite are fully mixed, the remaining binders are dissolved in water and sprayed, wet granulation is carried out, and the granules are dried; finally, total mixing is carried out, and the tablet is pressed to be prepared. Through the improvement of the preparation process, the stability and content uniformity of B vitamins are improved, and the growth-promoting effect is improved.

The invention relates to the technical field of biology, and particularly discloses a special diet nutrient solution for promoting growth and development and a preparation method thereof. The invention discloses a special diet nutrient solution for promoting growth and development. Comprising the following raw materials in parts by weight: animal-derived collagen peptide, milk-derived peptide, isomaltooligosaccharide powder, plant-derived bioactive peptide, yeast extract, salmon nasal cartilage composite powder, cereal oligopeptide, N-acetylneuraminic acid, BioPerine black pepper extract, L-calcium lactate, zinc gluconate, magnesium gluconate, vitamin B group composition, beta-carotene powder and acerola cherry fruit powder. The sour cherry concentrated powder, the roxburgh rose powder, the seasoning components and the balance of purified water are added. The product disclosed by the invention has the advantages of being high in nutrient content, good in absorptivity and capable of promoting growth and development.

The present invention relates to a method for the treatment of keratin fibres comprising the application, to the fibres, of a composition comprising at least one chemical oxidizing agent, at least one (bi)carbonate and at least one silicate, this application being preceded and / or followed by the application, to the keratin fibres, of a composition comprising one or more compounds chosen from organic acids, amino acids, chitosans, vitamins B, vitamin C, vanillin, their salts, their solvates and their mixtures.

The invention relates to the technical field of foliar fertilizers, in particular to a foliar fertilizer for prolonging the leaf color viewing period of a color-leafed plant. The foliar fertilizer is prepared from the following components in 100 parts by weight: 0.5 to 1.5 parts by weight of vitamin B compounds, 0.01 to 0.05 part by weight of benzylaminopurine compounds, 0.02 to 0.05 part by weight of ethylenediamine tetraacetic acid chelated titanium, 0.3 to 0.5 part by weight of rhamnolipid, 0.4 to 0.8 part by weight of malic acid, 0.5 to 1.5 parts by weight of modified polyethylene glycol and 0.5 to 1.5 parts by weight of modified cellulose nanocrystals.

The invention discloses a solid beer-flavor effervescent tablet and a preparation method thereof. The solid beer-flavor effervescent tablet comprises an acid source, an alkali source, a beer-flavor matrix, a sweetening agent, a filling agent, a nutrition enhancer and a processing aid, wherein the acid source comprises anhydrous citric acid, and the alkali source comprises sodium bicarbonate; the beer flavor matrix comprises malt flour, a humulus lupulus extract and a flavor enhancer, and the flavor enhancer comprises flavor essence and concentrated guava juice; the nutrition enhancer comprises vitamin B, mineral salt and an amino acid composition. According to the invention, rich and pure beer flavor and rich, fine and lasting foam can be generated after the beer is disintegrated in water, and the beer has good portability and long shelf life, and has a nutrition supplementing function.

The present application provides a kind of complex probiotic paste, which combines Enterococcus faecalis, Saccharomyces cerevisiae and vitamin B 12 Producing lactic acid bacteria of canine source, adds prebiotics, flavoring substances and auxiliary substances such as paste matrix preparation.In the paste, the viable count of Enterococcus faecalis, Saccharomyces cerevisiae and lactic acid bacteria is 1-2:1-2:1-8;Paste matrix includes fructooligosaccharide 0.5-3%, psyllium husk powder 0.1-2%, goat milk powder 2-8%, chicken liver powder 1-5%, potassium sorbate 0.5-2%, xanthan gum 1-4%, and the balance is water.The above-mentioned complex probiotic paste can be stably stored for 56 days at 4 DEG C and normal temperature dry place, has good storage stability, good safety, and can adjust intestinal flora and increase the content of intestinal lactic acid bacteria.The above-mentioned complex probiotic paste has good palatability and oral tolerance for pets such as dogs and cats, and has good therapeutic effect on DSS-induced chronic enteritis diarrhea and vitamin B 12 Deficiency.

The invention discloses a multi-vitamin microcapsule as well as a preparation method and application thereof, and belongs to the technical field of medicine manufacturing industry and dietary nutrition supplements. The preparation method comprises the following steps: selecting plant raw materials, and performing extraction, alcohol precipitation, stirring and drying to obtain plant mucus polysaccharide powder; mixing polyglycerol polyricinoleate with sunflower seed oil, adding beta-carotene and vitamin D3, and stirring to obtain an oil phase; dissolving vitamin B1, vitamin B2 and vitamin C in water to obtain a water phase; dissolving the plant mucus polysaccharide powder in water, adding maltodextrin and Arabic gum, and uniformly stirring to obtain a wall material solution; adding the water phase into the oil phase, shearing, mixing with the wall material solution, shearing, homogenizing at high pressure, emulsifying and homogenizing to obtain a homogenized liquid material; and carrying out spray drying to obtain the multi-vitamin microcapsule. The multi-vitamin microcapsule has high encapsulation efficiency and good structural stability, and the stability of vitamins can be remarkably improved.

The invention belongs to the technical field of vitamin content detection, and particularly relates to a method for measuring the content of various water-soluble vitamins B. The water-soluble vitamins B comprise vitamin B1, vitamin B2, vitamin B3, vitamin B6, vitamin B7, vitamin B12 and nicotinamide. A high performance liquid chromatograph and an electrospray detector are used as detection instruments, and chromatographic conditions are as follows: a mobile phase A is ammonium formate or ammonium acetate, a mobile phase B is methanol, and gradient elution is performed; the gradient elution procedure is as follows: a solvent of a test sample is a mixed solution of acetonitrile, water and glacial acetic acid, and the volume ratio of the acetonitrile to the water to the glacial acetic acid is 5: 95: 0.5; the atomization temperature of the electrospray detector is 35 DEG C; the method is better in separation degree and higher in specificity and sensitivity.

The invention discloses a preparation for improving male erectile function and sperm quality. The health-care food is characterized by being prepared from the following raw materials in parts by weight: 30-50 parts of herba epimedii extract, 20-40 parts of herba cistanche extract, 15-30 parts of fructus lycii extract, 18-35 parts of semen cuscutae extract, 10-25 parts of herba cynomorii extract, 8-20 parts of maca powder, 6-18 parts of raspberry extract, 0.5-2 parts of lycopene, 1-3 parts of L-carnitine and 0.3-1 part of vitamin B family (vitamin B1, vitamin B2, vitamin B6 and vitamin B12 are mixed according to the mass ratio of 1: 1: 2: 0.5). The herba epimedii extract is selected as a main component, the content of icariin is regulated to be not lower than 60%, the high-content icariin can more effectively promote sex hormone secretion, enhance sexual desire and improve erectile function, the total content of echinacoside and verbascoside in the herba cistanche extract is not lower than 45%, and the herba epimedii extract and the herba cistanche extract have the effect of promoting sex hormone secretion, enhancing sexual desire and improving erectile function. The two components have the effects of tonifying kidney yang and benefiting essence and blood, and can enhance kidney functions.

The invention discloses a double-jujube ginger powder multivitamin tablet. The feed additive comprises the following components in parts by weight: 30-45 parts of soybean protein isolate, 10-20 parts of ginger powder, 8-15 parts of sea-buckthorn powder, 8-15 parts of jujube powder, 9-16 parts of elaeagnus angustifolia powder, 5-10 parts of ancient brown sugar, 2-5 parts of perilla leaf powder, 1-5 parts of orange peel powder, 1-3 parts of clove powder, 1-4 parts of resistant dextrin, 2-5 parts of maltodextrin, 1-6 parts of ferric pyrophosphate, 1-2 parts of vitamin A and 1-2 parts of vitamin C. The composition comprises, by weight, 3 parts of vitamin D, 3-12 parts of vitamin B, 1-2 parts of folic acid and 2-6 parts of a compound colorant. According to the invention, the double-jujube ginger powder multivitamin tablet is researched and developed on the basis of the pathogenesis cognition of the traditional Chinese medicine pernicious vomiting of the traditional Chinese medicine and the theory of homology of medicine and food, and is innovatively combined with sea-buckthorn, jujube, elaeagnus angustifolia, ginger, multivitamin and mineral substances, so that the safe nutritional supplement tablet which helps to solve the vomiting during pregnancy and is suitable for women during pregnancy is provided.

The invention relates to a vitamin B effervescent tablet and a preparation method thereof, and belongs to the field of vitamin effervescent tablet production. 5-8 parts of tea powder; 70 to 80 parts of a filling agent; 90 to 110 parts of a disintegrating agent; 0.05 to 0.12 part of a lubricant; and 1.2 to 1.8 parts of a wetting agent. According to the vitamin B effervescent tablet, disintegrating agent particles are coated with an HPMC-shellac composite film, the dual functions of humidity shielding and rapid dissolution are achieved, the vitamin B effervescent tablet is convenient to eat and does not disintegrate in advance even if being exposed in air for a certain time, meanwhile, the tea powder is used as a natural flavor agent for middle-aged and elderly people, the resistance psychology of the middle-aged and elderly people can be relieved, and the immunity of the middle-aged and elderly people can be improved. Therefore, the storage stability and attraction of the vitamin B effervescent tablet are improved.

Compositions and methods for treating diseases that are responsive to the coadministration of AKG and certain B vitamins are described herein. In addition, compositions and methods for treating host animals that may not respond to AKG monotherapy, including treating host animals having inadequate or dysfunctional expression of enzymes involved in vitamin B metabolism and homeostasis, such as methylenetetrahydrofolate reductase (MTHFR), are described herein.

1. The name of this design product: Label (Vitamin B Water). 2. Purpose of this design product: for decorative packaging. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the key points of the design: Main view of Design 1. 5. Designs 1 and 4 are all flat products and the rear view is not commonly used. The rear view, left view, right view, top view, and bottom view of Designs 1 and 4 are omitted. 6. Designate Design 1 as the base design. 7. Other circumstances that require explanation: Request for protection of the colors of Design 1 and Design 3.

The invention discloses a pet hair beautifying food and a preparation method thereof. The pet hair beautifying food is prepared from the following raw materials in percentage by weight: 85.0%-88.0% of fresh chicken breast, 5.0%-6.0% of fresh chicken liver, 2.0%-3.0% of krill oil, 1.5%-2.5% of krill meal, 1.0%-2.0% of fish oil and an additive, the additive comprises 0.2% of sodium hyaluronate, 0.1% of natural vitamin E and 0.1% of vitamin B. The pet hair beautifying food is good in palatability and has a hair beautifying effect.

The invention belongs to the technical field of medical care, and relates to a composition for dispelling effects of alcohol and protecting liver, application of the composition, a microneedle composition and a preparation method. The alcohol effect dispelling and liver protecting composition is prepared from the following components in parts by weight: 10 to 30 parts of glutathione, 3 to 12 parts of vitamin B, 10 to 30 parts of vitamin C derivative, 5 to 15 parts of taurine, 0.5 to 1.5 parts of aescin and 3 to 7.5 parts of red ginseng extract. The application refers to the application of the alcohol effect dispelling and liver protecting composition in preparation of an external product for dispelling the alcohol effect and protecting the liver. The microneedle composition takes the alcohol effect dispelling and liver protecting composition as an active ingredient. According to the invention, glutathione, B vitamins, vitamin C derivatives, taurine, aescin and red ginseng extract are taken as main components, so that the anti-alcoholism liver-protecting composition has good anti-alcoholism and liver-protecting effects, and also can promote detoxification and detoxification functions of the liver. Meanwhile, the composition for dispelling the effects of alcohol and protecting the liver is combined with the soluble microneedle, and through painless transdermal administration, the dosage is smaller, and the composition has better patient compliance.

Disclosed is an efficacious, low-pH skin care composition that provides good sensory properties and has a low skin irritation potential. The low-pH composition includes an effective amount of a vitamin B3 compound and, optionally, one or more additional skin care actives to provide a skin health and / or appearance benefit. The low-pH composition also includes a pH buffer comprising lactic acid and sodium lactate, a polymer thickener comprising polyacrylate crosspolymer-6, and a silicone fluid having a kinematic viscosity of 100 cSt or less at 25° C. The pH of the low-pH composition can range from 2.0 to 5.0.