The invention relates to a new mixed micelle core-shell SiO2/Fe3O4 nanometer solid phase extracting agent in the chemical analysis test instrument device field, which has the big specific surface area of the nanometer material, the strong magnetic separating property of the magnetic material, the good satiability of SiO2 shell layer and the good extraction property of the semi micelle and the absorption micelle, and is fit for the large scale batch preconditioning of bulk water sample, and has the small usage extracting agent, high efficient extraction, the simple operation, the high extracting speed, the friendly environment, the wide using range, the low cost and the reactivation property. Selecting bisphenol A(BPA), nonyl phenol(4-OP), octyl phenol (4-NP) as the represent of the hydrophobic pollution material and selecting perfluorine enanthic acid (PFHeA), perfluorooctanoic acid (PFOA), perfluorine octane sulfonic acid (PFOS), perfluorine n-nonanoic acid (PFDeA) or the like perfluorine compound as the represent of amphipathic nature pollution material, there are 0. 1g extracting agent and 50mg surface activator in 800ml environmental water simple, and the extracting ratio of the organic pollution materials is more than 90%.