This invention discloses a method for preparing
capsaicin-like substances by temperature-responsive eutectic
solvent extraction, comprising the following steps:
drying Yunnan chili peppers (after removing stems and seeds), pulverizing, sieving, and collecting the
chili powder; mixing
lidocaine (HBA) with six
alkane-chain carboxylic acids (
valerate,
hexanoic acid,
heptanoic acid, octanoic acid,
nonanoic acid, and
lauric acid) at a 1:1
molar ratio to form a homogeneous and transparent liquid, TRDES; weighing the
chili powder, adding it to the TRDES
aqueous solution, and extracting by shaking; after extraction, centrifuging, and diluting the supernatant to obtain
capsaicin-like substances. This invention uses temperature-responsive eutectic
solvent extraction to prepare
capsaicin-like substances, which is simple, highly efficient, and allows for the recycling of extraction reagents, effectively saving resources. It has significant practical and industrial value for promoting the large-scale production of capsaicin-like substances and enhancing their high-value applications.