230 results about "Aminocaproic acid" patented technology

Aspects of the invention relate to methods for the production of difunctional alkanes in host cells. In particular, aspects of the invention describe components of genes associated with the difunctional alkane production from carbohydrate feedstocks in host cells. More specifically, aspects of the invention describe metabolic pathways for the production of adipic acid, aminocaproic acid, caprolactam, and hexamethylenediamine via 2-ketopimelic acid.

The present invention relates to a bone-repairing composite polymer material containing a ceramic ingredient and a preparation method thereof. The bone-repairing composite polymer material is composed of the calcium phosphate ceramic ingredient and a polybasic amino acid polymer ingredient, wherein, the mass ratio of the calcium phosphate ceramic ingredient is between 5 percent and 30 percent, and the rest is the polybasic amino acid polymer ingredient. Epsilon-aminocaproic acid is polymerized with at least two other types of amine acids to form the polybasic amino acid polymer ingredient, wherein, the mole ratio of the epsilon-aminocaproic acid in the polybasic amino acid polymer ingredient is between 50 percent and 90 percent, and the rest is the other amine acids including aminoacetic acid, lactamic acid, phenylalanine, lysine and proline. Under the protection of a inert gas, the materials, the amine acids and the calcium phosphate, are sufficiently and uniformly dispersed into water and then heated, so that various forms of waters can be removed from the materials, and finally, the materials are polymerized in two steps, respectively under a temperature between 200 DEG C and 220 DEG C and a temperature between 230 DEG C and 250 DEG C. The bone-repairing composite polymer material, which has excellent mechanical property, bioactivity, biocompatibility and controllable degradation property, can be perfectly combined with the interface of the bone tissue, and moreover, the degradation product is non-toxic and non-irritant.

The invention discloses a method for preparing an organic ternary polycarboxylic acid dustless antirust additive 2,4,6-tri(amino caproyl)-1,3,5-triazine by adopting a one-pot method, which comprises the following steps of: ring-opening caprolactam with alkali to generate carboxylate of aminocaproic acid first; then performing a substitution reaction by the carboxylate of aminocaproic acid and cyanuric chloride; and finally, acidizing with hydrochloric acid to prepare derivatives of organic ternary polycarboxylic acid. The preparation method is free from a toxic organic solvent and employs common water as a solvent for reaction. The preparation method ha the advantages of simple process operation, low production cost and low environmental pollution and is more suitable for large scale industrial production.

A peptide of the formula IX-A-D-Trp-Ywherein X is hydrogen, glycine, alanine, leucine, isoleucine, valine, N-valine, proline, tyrosine, phenylalanine, tryptophan, D-alanine, D-leucine, D-isoleucine, D-valine, D-N-valine, D-proline, D-tyrosine, D-phenylalanine, D-tryptophan, gamma -aminobutyric acid or xi -aminocaproic acid; A is D-gluptamic acid or D-y-glutamic acid; and Y is glycine, alanine, leucine, isoleucine, valine, N-valine, proline, tyrosine, phenylalanine, tryptophan, D-alanine, D-leucine, D-isoleucine, D-valine, D-N-valine, D-proline, D-tyrosine, D-phenylalanine, D-tryptophn, gamma -aminobutyric acid, xi -aminocaproic acid, hydroxyl, or an amide group.

A method for inhibiting and dissolving the deposits formed on caustic or alkaline scrubbers used in scrubbing acidic gases such as carbon dioxide, hydrogen sulfide, which are formed during the pyrolytic cracking of naphtha, ethane, and propane. The cracking operations produce certain oxygenated compounds such as vinyl acetate or acetaldehyde, which undergo polymerization under alkaline condition. The vinyl acetate on hydrolysis releases acetaldehyde under alkaline conditions. Amino acids such as 6 amino caproic acid and lactams such as epsilon caprolactam not only prevent but also dissolve the polymers formed by aldol condensation.

The invention discloses a polyamide thermosol, containing the following copolymer monomers: A. one or many kinds of hexanolactam, amino-caproic acid, 11-aminoundeeanic acid and laurolactam; B. one or many kinds of mixtures formed of C4-C9 aliphatic dicarboxylic acid and equivalent C2-C12 aliphatic diamine or their nylon salts; C. one or many kinds of mixtures formed of C10-C15 long-carbon chain aliphatic dicarboxylic acid and equivalent C4-C12 diamine or vinyl-amine or their nylon salts. It has high melting point, narrow fusing temperature range, high bonding strength, good low-temperature flexibility and high-temperature resistance, and can be applied to binding metal material, metal-plastic laminated composite, and car light.

The present invention relates to a solid composition useful for tissue gluing, tissue sealing and haemostasis consisting essentially of a) a carrier which has at least one of the following physical properties: elasticity module in the range of 5-100 N/cm, density of 1-10 mg/cm3, chamber diameter of more than 0.75 mm and less than 4 mm and/or having a chamber diameter average below 3 mm and evenly distributed and fixed upon said carrier, b) solid fibrinogen, and c) solid thrombin. The carrier is a biodegradable polymer such as a polyhyaluronic acid, polyhydroxy acid, e.g. lactic acid, glucolic acid, hydroxybutanoic acid, a cellulose, gelatine or collagen, such as a collagen sponge, e.g. a collagen sponge consisting essentially of collagen type I fibres. The fibrinogen and thrombin are preferably human, purified from a natural source, or transgenic or recombinant human fibrinogen and/or thrombin. In a preferred embodiment the composition does not comprise any antifibronolytic agent such as aprotinin, epsi-aminocaproic acid or alpha2-antiplasmin,

The invention discloses a method for synthesizing hexanediamine by taking caprolactam as a raw material. The method comprises the following steps that (1) after the hexanediamine, alkali and water aremixed, heating reflux is conducted, and thus 6-amino-caproate is obtained; (2) the 6-amino-hexanoate obtained in the step (1) is introduced into an amino protecting group to protect an amino end group, then acid is added for neutralization to generate aminocaproic acid with the amino protecting group; (3) after a product obtained in the step (2) is dried, a dehydration catalyst for amide is added, a heating reaction is conducted in the presence of an ammonia source to convert a carboxylic acid group into a cyano group, and thus product nitrile is obtained; and (4) after the product nitrile obtained in the step (3) is extracted and purified, catalytic hydrogenation is conducted to generate corresponding amine, then the protecting group is removed, and thus a target product can be obtained.

The invention discloses a process for preparing Quinclorac artificial semiantigen, artificial antigen, specific antibody and use thereof, wherein the preparation comprises, subjecting the dichloroquine (3,7-dichlorine-8-quinoline carboxylic acid) to sulfoxide chlorinated acylation, reacting with reanal and aminocaproic acid, thus obtaining semiantigen 4-(3,7-dichlorine-8-quinolineformyl) reanal or 6-(3,7-dichlorine-8-quinolineformyl) aminocaproic acid (QB or QC).

A segmented copolyamide and its production are disclosed. The copolyamide consists of any one of monomer 11-amino-hendecanoic acid, 12-amino-lauric acid and 6-amino acetic acid or hydantoinamine, glycine, propalanine, 8-aminocaprylic acid or octane lactam, 9-amino-nonoic acid or nonane lactam, 10-amino-qunane acid or quinane lactam, 11-amino-hendecanoic, dodecanoic lactam or 12-amino-lauric acid or 14-amino-tetradecoic acid. The process is carried out by copolymerization reacting the raw materials with their related preformed polymer. It achieves low cost, various nylon resin products and better properties.

The invention relates to lactic acid-amino acid copolyester amide and a preparation method thereof and relates to the technical field of the copolyester amide. The lactic acid-amino acid copolyester amide can be used for improving thermal stability and mechanical strength of a polylactic acid material, and also can be used as a compatibilizer in the blending of polylactic acid and nylon. The lactic acid-amino acid copolyester amide is prepared by copolymerization of any amino acid and lactic acid, wherein the monomer of any amino acid can be 11-amino undecanoic acid, 12-amino dodecanoic acid and 6-aminocaproic acid or caprolactam, glycine, aminopropionic acid, aminobutyric acid, 8-aminocaprylic acid or octane lactam, 9-aminononanoic acid or nonane lactam, 10-amino decenouc acid or decane lactam, dodecane lactam, 14-amino tetradecanoic acid. According to the lactic acid-amino acid copolyester amide and the preparation method thereof disclosed by the invention, the polylactic acid products are various, the thermal performances and the mechanical performances of the polylactic acid products are improved and the application range of the material is more extensive.

The invention discloses preparation methods and applications of a benzylpenicilloic acid artificial antigen and a benzylpenicilloic acid artificial antibody, and relates to a method for simply, quickly and effectively detecting penicillin G and a degradation product of penicillin G, namely benzylpenicilloic acid. The specific antibody to penicillin G and the degradation product of penicillin G, namely benzylpenicilloic acid, is prepared by designing and synthesizing a hapten and the artificial antigen of a penicillin veterinary drug penicillin G with a 6-aminocaproic acid molecular structure and a beta-lactam ring molecular structure, and the degradation product of penicillin G, namely benzylpenicilloic acid; a molecular specific antigenic determinant of the veterinary drug is highlighted; the chemosynthesis difficulty is overcome; and an immune animal induces to generate the specific antibody with very high affinity.

The invention relates to an injection moldable bone repair composite material and a preparation method and a using method thereof. The composite material is a powder material consisting of a copolymer of multiple amino acids and a sulfate component of calcium, the sulfate component of the calcium accounts for 60-95% of total weight of the component material, and the balance is the copolymer of the multiple amino acids. The sulfate component of the calcium comprises alpha-hemihydrated calcium sulfate which accounts for 15%-60% of the total weight of the composite material and the balance of other sulfates of the calcium. The copolymer of the multiple amino acids is formed by polymerizing epsilon-aminocaproic acid and at least two types of other amino acids, and the molar ratio of each amino acid in the other amino acids is not less than 1% of the total weight of the amino acids. When in preparation, an intermediate parent body is obtained by in-situ polymerization and composition of other sulfates of the calcium and the amino acid monomers under inert gas protection and heating, and the composite material is prepared by smashing and then being composed with the alpha-hemihydrated calcium sulfate. The composite material powder is mixed with curing liquid, and then the composite material can be used by injection. The composite material can be fast molded after the injection and has the strength which is equivalent to that of cancellous bone, good biocompatibility and adjustable degradation speed, thereby being applicable to fixation and repair of clinical orthopedic complicated and irregular traumas.

The present invention provides a method for making 6-aminocaproic acid as an active pharmaceutical ingredient. The method comprises: performing a hydrolysis procedure to have ε-caprolactam react with acid or base to generate a first reaction mixture, performing a modification procedure to have a solubility regulating agent reacts with 6-aminocaproic acid in the first reaction mixture to form a second reaction mixture including an aminocaproic acid intermediate, performing a separation procedure to have the intermediate separated from the second reaction mixture and performing a hydrogenation procedure to have the aminocaproic acid intermediate hydrogenated to form a 6-aminocaproic acid product.