109 results about "Dodecane" patented technology

The invention provides a fracturing fluid base fluid, a water-based fracturing fluid and a preparation method of the water-based fracturing fluid, and relates to the technical field of oil fields. The fracturing fluid base fluid is prepared from the following components in percentage by mass: 97.3 percent to 98.1 percent of produced water, 0.5 percent to 0.55 percent of hydroxypropyl guar gum, 0.004 percent to 0.005 percent of sodium hypochlorite, 0.015 percent to 0.03 percent of citric acid, 0.1 percent to 0.18 percent of dodecyl dimethyl benzyl ammonium bromide, 0.2 percent to 0.3 percent of ethylenediamine tetraacetic acid disodium salt, 0.3 percent to 0.5 percent of a temperature stabilizer, 0.6 percent to 0.8 percent of a pH value regulator and 0.2 percent to 0.3 percent of a cleanup additive; the pH value of the fracturing fluid base fluid is 7.5. The fracturing fluid base fluid prepared from the produced water has the advantages of rapid adhesion, no precipitation, no weak crosslinking and no floccule phenomenon, so that the guar gum fracturing fluid prepared from the fracturing fluid base fluid has the characteristics of self-adaption to a reservoir, ultralow damage and high performance.

The invention relates to high-heat-resistance polypropylene and a preparation method thereof, and belongs to the technical field of high polymer materials. The preparation method comprises the following steps: carrying out Michael addition reaction on 2-sulfydryl-1, 3-propylene glycol and vinyl dibutyl borate to prepare dihydric alcohol containing thioether and phosphate, and carrying out polymerization reaction on 1, 12-dodecanediol, boric acid ester dihydric alcohol and dimethyldichlorosilane to obtain the flame retardant. A polymer containing a borate group, a thioether group, organic silicon and a dodecane glycol ester group is prepared, the polymer is used as a heat-resistant toughening additive of polypropylene, the borate group and the organic silicon can improve the heat resistance and flame retardance of the polypropylene, and the thioether group and the dodecane glycol ester group can provide flexibility; therefore, the polypropylene is ensured to have good mechanical strength, heat resistance and flame retardance at the same time.

The present invention relates to a novel polymorph of (1R,2R,3aS,3bR,10aS,10bR,11S,12aS)-5,10b-difluoro-1-(((fluoromethyl)thio)carbonyl)-11-hydroxyl-2,10a,12a-trimethyl-7-phenyl-1,2,3,3a,3b,7,10,10a,10b,11,12,12a-dodecylhydrocyclapenta[5,6]napththo[1,2-F]indazole-1-furan-2-carboxylate ester as shown in formula (I), a preparation method therefor, and a use thereof. The crystal form of the present invention has characteristics such as a significant pharmaceutical effect, good stability, high yield, and high purity, and is beneficial for the selection and design of a drug administration route and the determination of a drug preparation process parameter, thereby improving drug production quality.

The invention relates to the technical field of catalyst preparation, and discloses a carbon modified copper-based catalyst and a preparation method and application thereof. The method comprises the following steps: (1) sequentially carrying out coprecipitation and aging on an alkaline precipitant solution, a metal salt solution and an anion modifier solution to obtain an intermediate product I; and (2) under the condition that the oxygen concentration is not higher than 5% by volume, roasting the intermediate product I to obtain the carbon modified copper-based catalyst, the anion modifier solution contains sodium dodecyl diphenyl ether disulfonate and sodium gluconate in a molar ratio of 1: (1-10); the pH value of the anion modifier solution is 9-11; the metal salt solution contains zinc salt, copper salt and aluminum salt. The prepared carbon modified copper-based catalyst has the advantages of high conversion per pass of carbon dioxide, low activation temperature, high methanol selectivity, long-period operation and stable structure.

The invention discloses a flotation collecting agent formula based on quartz, a preparation method and an extraction method. The flotation collecting agent formula comprises a cation collecting agent and an anion collecting agent which are used in cooperation. Wherein the cation collecting agent is prepared from the following components in parts by weight: 10 to 40 parts of dodecyl amine, 10 to 40 parts of coconut oil alkylamine, 2 to 8 parts of dodecyl trimethyl ammonium chloride, 1 to 4 parts of a nonionic surfactant, 2 to 8 parts of ethanol and 5 to 10 parts of hydrochloric acid; the anion collecting agent comprises a sulfonate surfactant; the use of hydrofluoric acid is greatly reduced, fluorine pollution is reduced, the anionic collector and the cationic collector are compounded to play a synergistic role, implementation can be carried out under the weak acid condition, agent preparation and process control are simple and convenient, the agent dispersity is good, temperature and ore property fluctuation can be adapted, the flotation selectivity and recovery rate of quartz and feldspar can be remarkably improved, and the flotation efficiency is improved. The resource utilization value of the tailings is improved.

The present invention relates to an improved process for the preparation of macrocyclic chelant 2,2′,2″-(10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl) triacetic acid of formula (1). The present invention further relates to the process for the preparation of metal complexes of macrocyclic chelant 2,2′,2″-(10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl) triacetic acid of formula (1) with purity greater than 99.0% by HPLC. The present invention also relates to an improved process for the preparation of gadolinium complex of formula (1a) with macrocyclic chelant 2,2′,2″-(10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl) triacetic acid of formula (1). The present invention further relates to a novel process for the preparation of calcium complex of formula (1b) with macrocyclic chelant 2,2′,2″-(10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl) triacetic acid of formula (1).

This invention relates to the field of metal surface treatment technology, and discloses a magnesium-silver alloy cleaning agent and its preparation and cleaning methods, comprising: a shear coupling step, in which dodecylamine and organophosphonic acid are mixed in an alcohol ether solvent at 60-65℃ and 2500-3000rpm under high shear to construct a high-energy acid-amine assemblage; a hysteresis locking step, in which the shear rate is maintained constant and the temperature is lowered to 35-40℃ at a rate of 1.5-2.0℃ / min to inhibit crystallization and lock it into a metastable precursor; and a dispersion stabilization step, in which a nonionic surfactant is added and dispersed to a semi-transparent state. This invention utilizes the rheological antagonistic mechanism of shear thinning and cooling viscosity increase to construct a metastable system with synchronous transport characteristics, eliminates the kinetic lag caused by preferential solvent wetting, realizes zero-time-difference synchronous adsorption of corrosion inhibitor and solvent on the magnesium-silver interface, and improves the storage stability of the cleaning agent.

The invention discloses a method for synthesizing biphenol in a water phase, belongs to the technical field of fine chemical engineering, and aims to solve the explosion safety risk caused by the use of an organic solvent in the conventional alkylphenol oxidative coupling process. According to the method, a phase transfer catalysis system composed of boric acid, Tween-80, dodecylphenol polyoxyethylene ether and copper chloride is adopted, water serves as a solvent, oxygen or air is introduced at the temperature of 60-90 DEG C, alkyl phenol is subjected to an oxidative coupling reaction to generate alkyl biquinone, and then biphenol is prepared through hydrogenation reduction. The method thoroughly avoids the use of an organic solvent, eliminates the hidden danger of explosion from the source, and has the advantages of high intrinsic safety, environmental friendliness and low cost.

The invention provides a preparation method and application of macrocyclic multi-amino porous organic aerogel, and belongs to the field of catalysts. The preparation method comprises the following steps: reacting tetraazacyclododecane with chloromethyl styrene to obtain an intermediate; and carrying out sol-gel polymerization on the intermediate, and drying to obtain the macrocyclic multi-amino porous organic aerogel. As a thermal insulation material and a heterogeneous catalyst, the macrocyclic multi-amino porous organic aerogel can be applied to thermal insulation and cycloaddition reaction of a halogenated epoxy substrate and carbon dioxide, and has the characteristics of high conversion rate and high selectivity.

The application discloses a preparation method of a titanium dioxide coated MIL-53(Fe) electrocatalyst. First, a catalyst MIL-53(Fe) is obtained through a hydrothermal method, then the catalyst is heated, stirred and dried under mild conditions, and titanium dioxide obtained by hydrolysis of tetra-n-butyl titanate is uniformly coated on the MIL-53(Fe) under the action of dodecyl sulfate, finally, the catalyst is improved in contact with nitrogen through heat treatment, so that the titanium dioxide coated MIL-53(Fe) with good stability is prepared.

The invention discloses a preparation method of a sodium lauryl glycol carboxylate compound, which comprises the following specific steps: adding 1, 2-epoxydodecane and glycolic acid into a first reaction flask containing a solvent, and carrying out heating reaction under the action of a large-steric-hindrance catalyst to obtain lauryl glycol acetic acid; wherein the solvent is cyclohexane, normal hexane or methylbenzene, and the large steric hindrance catalyst is tri (pentafluorophenyl) borane; and S3, adding the lauryl glycol acetic acid prepared in the step S1 into a second reaction flask containing water, and adjusting the pH value of the solution in the second reaction flask to 8.5-11.5 by using a certain amount of sodium hydroxide solution to prepare lauryl glycol sodium carboxylate, namely the target compound. According to the preparation method disclosed by the invention, the single selectivity of the synthesis process is improved, so that the purity and yield of the sodium lauryl glycol carboxylate compound synthesized by the route are greatly improved, and the product becomes better and better in application.

This invention discloses a novel method for preparing a clean fuel additive, relating to the field of clean fuel additive technology. Its components include: a main cleaning agent: Mannich base; a dispersant: polyetheramine; a surfactant: highly active polyisobutylene; an antioxidant: N,N-di-sec-butyl-p-phenylenediamine; an octane booster: dimethyl carbonate; a solvent: 120# solvent oil; a combustion improver: C9-C11 mixed olefins; a stabilizer: trimethylolpropane; an ignition promoter: nitrobenzene; and auxiliary additives: n-dodecane, sodium polystyrene sulfonate, and eugenol methyl ether. This invention achieves a significant synergistic effect among the core components such as Mannich base, polyetheramine, polyisobutylene, amine antioxidants, and dimethyl carbonate. This synergistic effect allows the additive to comprehensively optimize the cleanliness, anti-knock properties, stability, and combustion efficiency of fuel at a relatively low total addition amount.

The invention relates to the technical field of cyclododecanol production, in particular to a method for inhibiting by-product cyclododecane in a cyclododecanol hydrogenation preparation process, which comprises the following steps: mixing one or more of cyclododecanone, epoxy cyclododecane or epoxy cyclododecene as raw materials with a solvent to prepare a raw material solution; the raw material liquid is subjected to a hydrogenation reaction, cyclododecanol is prepared, and the water content in the raw material liquid is 3-15 wt%. By adopting the technical scheme provided by the invention, on the premise of not changing the catalyst and the reaction system, the water content in the raw material liquid is controlled to be 3-15wt%, so that the water content of the reaction system in the reaction process is in a proper range, the generation of a byproduct cyclododecane can be effectively inhibited, and the yield of cyclododecanol is obviously improved; and the yield of the byproduct cyclododecane is reduced, so that the heat load of the tower kettle of the light component removal tower can be reduced by 20-50%.

This invention discloses a semi-synthetic metalworking fluid with rust-preventive properties and its preparation method. The fluid comprises, by mass fraction of raw materials: 25-30 parts base oil, 3-5 parts composite corrosion inhibitor, 0.1-0.3 parts non-ferrous metal corrosion inhibitor, 12-15 parts pH stabilizer, 8-11 parts main emulsifier, 3-5 parts auxiliary emulsifier, 0.8-1.5 parts calcium soap dispersant, 0.8-1.0 parts coupling agent, 2.5-3.5 parts bactericide, and 27.7-44.8 parts water. This invention utilizes a composite corrosion inhibitor of dodecyl diacid (DDDA) and triazine polycarboxylic acid derivatives, compounded in a specific ratio, to construct a dual protective mechanism of "microscopic hydrophobic adsorption" and "macroscopic chemical passivation" on the metal surface. This synergistic effect greatly enhances the density and adhesion of the protective film.

The application provides a Bacillus velezensis TCS001 volatile gas composition, which comprises 2-ethylhexanol, methyl nonyl methyl ketone, 2-decanol and 2-dodecanone, and the mass ratio of 2-ethylhexanol:methyl nonyl methyl ketone:2-decanol:2-dodecanone is 2-7:5-13:2-6:2-23. The Bacillus velezensis TCS001 volatile gas composition can be used as a safe and efficient gas-phase bacteriostatic material for the research and development of a novel fumigation preparation, is suitable for the prevention and treatment of diseases in a closed environment such as a greenhouse, a warehouse and the like, promotes crop growth, and has wide application value.

The application discloses a lithium salt particle size measuring method, and belongs to the technical field of material measurement. The measuring method comprises the following steps: step S1: obtaining a lithium salt powder to be measured; step S2: under the condition that the dew point temperature of a measuring environment is less than or equal to-45 DEG C, dispersing the lithium salt powder in a dispersion medium to form a lithium salt suspension; measuring the particle size of the lithium salt in the lithium salt suspension by using a particle size measuring device to obtain the particle size of the lithium salt powder; wherein the dispersion medium is selected from at least one of n-heptane, n-dodecane, n-undecane, n-decane, n-hexane, toluene, xylene, anisole and butyl butyrate. The lithium salt particle size measuring method is particularly suitable for the particle size measurement of hygroscopic / dissolvable samples, has high measurement precision and good repeatability, and the relative standard deviation (RSD) is less than 2%.

The invention discloses high-purity didodecyl dimethyl ammonium bromide and a preparation method thereof. The preparation method comprises the following specific steps: mixing lauryl amine, a formaldehyde aqueous solution and formic acid, and carrying out methylation reaction to obtain a reaction solution containing dodecyl dimethyl tertiary amine; adjusting the pH value of the reaction liquid containing dodecyl dimethyl tertiary amine to be alkaline, standing for liquid separation, and collecting a dodecyl dimethyl tertiary amine crude product; the method comprises the following steps: adding a dodecyl dimethyl tertiary amine crude product and 1, 4-dibromobutane into an inert organic solvent, mixing, and stirring for quaternization reaction to obtain a reaction mixture; and cooling the reaction mixture to obtain a precipitated solid, and recrystallizing to obtain the high-purity didodecyl dimethyl ammonium bromide. According to the preparation method, the process is simplified through a quasi-one-pot method, the raw material ratio, the reaction condition and the purification process are optimized, the product purity reaches 99%, and the preparation method is high in process integration degree and environmentally friendly and has important industrial application value.

The invention discloses a preparation method of isohexadecane solvent naphtha, which comprises the following steps: treating a raw material isohexadecane mixture by a feed adsorption tank and a feed filter, feeding into a feed buffer tank, boosting by a hydrogenation feed pump, mixing with recycle hydrogen, exchanging heat with reaction generated oil, and feeding into a pre-hydrogenation reactor; a pre-hydrogenation reaction product is mixed with high-pressure circulating oil and circulating hydrogen, is subjected to heat exchange with reaction generated oil, is fed into a hydrofining reactor, is subjected to heat exchange, is cooled, and is fed into a high-pressure separator; the reaction generated oil and the hydrogenation generated oil at the bottom of the high-pressure separator are sent to a product separation tower after components are removed by a light component removal tower; the product separation tower is provided with a side stream stripping tower, isohexadecane solvent oil is extracted from the bottom of the side stream stripping tower, and byproducts such as isododecane solvent oil and isoeicosane solvent oil are extracted from the top and the bottom of the separation tower respectively. The method prolongs the service life of the catalyst and the operation cycle of the device, reduces the operation energy consumption of the device, reduces the carbon emission and saves the investment.

The embodiment of the invention provides an asymmetric brush polymer and a preparation method thereof. The preparation method comprises the following steps: step S1, enabling 5-norbornene-2-exo, 3-exo-dimethanol to react with 2-(dodecyl thiocarbon thio) propionic acid, so as to obtain a norbornene derivative with 2-(dodecyl thiocarbon thio) propyl ester and a hydroxyl unit at the same time; s2, enabling the norbornene derivative to react with caprolactone and methyl acrylate by utilizing a light irradiation reaction system in the presence of a ring-opening polymerization catalyst and a photocatalyst, so as to obtain an asymmetric macromonomer containing polymethyl acrylate and polycaprolactone block units at the same time; s3, enabling the asymmetric macromonomer to react in the presence of a Grubbs catalyst, so as to obtain the asymmetric brush type polymer. By applying the technical scheme provided by the invention, the technical problems that in the prior art, the synthesis steps of the asymmetric brush type polymer are tedious, multiple purification is needed, and the molecular weight and distribution of the polymer are difficult to effectively control can be effectively solved.

This invention belongs to the field of catalyst technology, specifically relating to a multi-metal-doped cerium oxide catalyst and its preparation and application. The catalyst comprises a γ-Al₂O₃ support and an active component supported thereon, wherein the chemical formula of the active component is Ni. a Fe b Ru c Co d Ce1 a b c d O 2‑δ Wherein, 0.05≤a≤0.1, 0.04≤b≤0.06, 0.04≤c≤0.06, 0≤d≤0.06, and a+b+c+d≤0.2. The catalyst is prepared by solution impregnation, by preparing a metal salt solution and impregnating it on a γ-Al2O3 support to obtain a sol with a complexing agent, which is then aged, dried, and calcined in stages. The catalyst is used in the steam reforming reaction of aviation kerosene (n-dodecane simulation), and can achieve 100% catalytic conversion at 700 °C, without deactivation after 100 h of continuous operation, exhibiting low-temperature activity and anti-carbon deposition performance; wherein Ni 0.05 Fe 0.05 Ru 0.05 Co 0.05 Ce 0.8 O 2‑δ When reformed gas drives a tubular solid oxide fuel cell, the power density reaches 830.90 mW / cm³. 2 It operates stably for 100 hours without significant degradation. The process of this invention is simple and cost-controllable, and it is applicable to the fields of hydrogen production from aviation kerosene reforming and SOFC coupled power generation.

This invention discloses a low-temperature resistant composite flotation reagent for coal preparation and its preparation method, specifically relating to the field of flotation technology. The reagent is formed by emulsification of a composite collector, a composite frother, and an aqueous phase. The composite collector contains kerosene, n-dodecane, oleic acid, dimer acid, surfactant components, and low-temperature stabilizing components. The composite frother contains terpineol, pine oil, sec-octanol, and sodium α-olefin sulfonate, etc. Through compounding and synergistic effects, high-speed shear emulsification, and high-pressure homogenization, the obtained reagent exhibits good dispersibility and stability at -5 to 15°C, and can improve the flotation efficiency, clean coal yield, and combustible gas recovery rate of fine coal slime and high-ash, difficult-to-separate coal slime without heating the coal slurry.

Provided herein are use of an exosome, a complex comprising an exosome, a tracer, and a preparation method and use thereof. The complex comprises an exosome, a bifunctional chelating agent coupled to the exosome, and a radionuclide gallium-67 or gallium-68 embedded on the bifunctional chelating agent. In a preferred implementation, the bifunctional chelating agent comprises 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA).

The present application belongs to the technical field of deep-sea plume suppression, and particularly relates to a biomass flocculant, a preparation method and application thereof. The raw materials include sodium alginate, acrylamide and dodecane dimethyl betaine, wherein the mass ratio of sodium alginate and acrylamide to the volume of dodecane dimethyl betaine is 1g:(2-4)g:(0.5-1)ml. The present application uses natural or bio-based materials such as sodium alginate, acrylamide and dodecane dimethyl betaine as main components, fully utilizes marine polysaccharides as raw materials, and introduces dodecane dimethyl betaine on the molecule of the flocculant material to reduce the viscosity of the flocculant solution, thereby reducing the requirements on the pipeline and pumping device, improving the pumping efficiency of the flocculant, effectively suppressing the damage of the deep-sea plume to the ecological environment, and having good economic and environmental benefits. The product is non-toxic and has good biodegradability, avoiding the potential harm of traditional inorganic flocculants to the deep-sea ecological environment.

The application provides a kind of light regulated liquid crystal material composition and its preparation method, belongs to light regulated liquid crystal technical field, preparation method includes with docosyl-tetramethyl piperidinol propylene acid ester, (3-acryloyloxy-2-hydroxy propoxy propyl) end-capped polydimethylsiloxane, cyano biphenyl hexyl acrylate and other raw materials preparation adjuvant, nematic liquid crystal monomer, photoisomerization functional monomer, dynamic covalent crosslinking agent, photoinitiator and the mixed liquid consisting of cyclohexanone and propylene glycol methyl ether acetate are under the condition of controlled temperature, rotation speed and vacuum degree, low-speed stirring, high-speed shearing dispersion and vacuum degassing curing are carried out, to obtain light regulated liquid crystal material composition, the application is through the adjuvant design and the one-step method mixing process of simplification, the contradiction between material dynamic response performance and long-term stability is solved, the prepared composition shows millisecond level fast light response, high optical contrast, photo-induced deformation and good cycle durability after film curing.

The invention discloses a preparation method of an efficient light-emitting silver-indium-sulfur and silver-indium-zinc-sulfur composite nano material, and belongs to the technical field of light-emitting nano materials and preparation. The preparation method comprises the following steps: by taking silver dibutyl dithiocarbamate, indium dibutyl dithiocarbamate and zinc carboxylate as precursors, uniformly mixing at a dodecane neutralization pretreatment temperature to form a mixed solution A; naturally cooling, adding dodecanethiol, and uniformly stirring and mixing to obtain a mixed solution B; at the reaction temperature, decomposing part of silver dibutyldithiocarbamate in the mixed solution B to generate silver sulfide clusters; the activity of the silver sulfide cluster is closely related to the size, the silver sulfide cluster is used as a seed to induce growth of silver-indium-zinc-sulfur, meanwhile, silver sulfide is converted into silver-indium-sulfur, finally, the silver-indium-sulfur and silver-indium-zinc-sulfur composite nano material is obtained, the band gap is 2.0-2.8 eV, the luminous efficiency is 52% or above, and the luminous efficiency can still be kept at 78% or above after five months. The preparation process disclosed by the invention is low in raw material cost and good in process controllability.

The present invention relates to a method for preparing hydrocarbon double acids using a cyclic hydrocarbon oxidation catalyst, wherein adipic acid and dodecanedioic acid may be produced with high yield while solving the problem of environmental pollution, the adipic acid and the dodecanedioic acid being prepared by using an oxidation reaction of a cyclohexane-cyclohexanone mixture and an oxidation reaction of a cyclododecane-cyclododecanone mixture, respectively, in the presence of a vanadium phosphate oxide-based catalyst and / or a cobalt-manganese oxide-based catalyst.

The invention discloses an additive for increasing the crystal size of calcium hydrophosphate and application of the additive, and belongs to the technical field of inorganic chemical industry. According to the additive for increasing the crystal granularity of the calcium hydrophosphate, the additive is at least one of cetylpyridinium bromide, cetyltrimethylammonium bromide and dodecyl benzyl dimethyl ammonium bromide. In addition, the invention also provides an application of the additive in increasing the crystal particle size of calcium hydrophosphate. The additive for increasing the crystal granularity of the calcium hydrophosphate, provided by the invention, can increase the granularity of the calcium hydrophosphate by more than 50%.

This invention relates to a novel polymorph of (1R,2R,3aS,3bR,10aS,10bR,11S,12aS)-5,10b-difluoro-1-(((fluoromethyl)thio)carbonyl)-11-hydroxy-2,10a,12a-trimethyl-7-phenyl-1,2,3,3a,3b,7,10,10a,10b,11,12,12a-dodecylhydrocyclopenta[5,6]naphtho[1,2-F]indazole-1-ylfuran-2-carboxylic acid ester as shown in formula (I), its preparation method, and its uses. The polymorph of this invention exhibits significant efficacy, good stability, high yield, and high purity, which is helpful for the selection and design of drug delivery routes and the determination of pharmaceutical formulation process parameters, thereby improving the quality of drug production. (I)

The invention relates to the technical field of organic synthetic chemistry, in particular to 1-{2-[3-(4-hydroxyphenyl) propionyl] diazo alkyl} docosan-1-ketone as well as application and a preparation method of 1-{2-[3-(4-hydroxyphenyl) propionyl] diazo alkyl} docosan-1-ketone. According to the method, docosanoic acid and 3-(4-hydroxyphenyl) propanohydrazide are used as raw materials, and in a polar aprotic solvent, a benzotriazole coupling reagent and organic base are adopted for catalysis and a coupling reaction is carried out. According to the method, one-step coupling without protecting groups can be realized, the synthesis efficiency is remarkably improved, and the production cost is reduced; the method also has the advantages of mild conditions, high yield, excellent product purity, safety, environmental protection, suitability for large-scale popularization and the like.

The invention discloses a synthesis method of octadecanedioic acid, and belongs to the field of chemical synthesis. The method comprises the following steps: adding phosphorus tribromide and acetonitrile into a three-neck bottle, and heating in a nitrogen atmosphere; then slowly dropwise adding a mixed solution of 1, 12-dodecanediol and DMF (Dimethyl Formamide), and after dropwise adding is completed, heating the reaction solution again and reacting; and cooling the reaction liquid, dropwise adding water, extracting with petroleum ether, washing a petroleum ether layer with a saturated saline solution, adding anhydrous sodium sulfate into the petroleum ether layer, and drying, filtering and concentrating to obtain a faint yellow solid. By constructing a molecular skeleton step by step, accurate regulation and control of an intermediate are realized, and complex side reactions are avoided. According to the method, mild reaction conditions are adopted, special requirements on equipment are effectively reduced, and meanwhile, energy consumption is reduced. In the aspect of raw material selection, expensive or highly toxic substances are replaced with commercialized reagents easy to obtain, and cost controllability and environment friendliness are both considered.