81 results about "Raney nickel" patented technology

This invention relates to a method for preparing hexamethylenediamine by hydrogenation of adiponitrile in the presence of a Raney nickel catalyst, wherein a Raney nickel catalyst modified by treatment with carbon monoxide or carbon dioxide in a liquid medium is used.

The invention relates to the technical field of sugar alcohol preparation, and discloses a preparation method of high-purity crystalline maltitol, which comprises the following steps: firstly, by taking corn starch milk as a raw material, preparing ultrahigh-content maltose syrup with the maltose content of more than or equal to 91%, the wheat triose content of less than or equal to 0.4% and the glucose content of less than or equal to 4% through an enzyme conversion method; carrying out hydrogenation reaction on the syrup by adopting a Raney nickel catalyst, and controlling the hydrogenation side reaction to be 2% or below, so as to obtain hydrogenated liquid with maltitol content of more than or equal to 88%; and then, a pigment separation procedure in a traditional process is omitted, and the hydrogenated liquid is directly subjected to decoloration, ion exchange, evaporation concentration, crystallization, centrifugation and drying treatment to finally prepare crystalline maltitol. According to the method, by screening a specific compound enzyme system and finely regulating the pH value and temperature control environment of a saccharification reaction system, the generation of maltose is effectively promoted, and side reactions such as excessive hydrolysis of glucose and reverse synthesis of trisaccharide are inhibited at the same time, so that the high-purity maltose syrup precursor is obtained.

The invention relates to a process for the manufacturing of biobased 3-methyl-delta-valerolactone (3MdVL) and 3-methyl-1,5-pentanediol (3MPD) via one- pot hydrogenation of anhydromevalonolactone (aMVL) in the presence of a Raney- Nickel catalyst. The hydrogenation occurs without solvent at a temperature from 120ºC-180ºC, preferably at 130ºC-170ºC and a pressure between 15-30 bar, preferably at a pressure between 18 and 22 bar. The hydrogenation time may vary between 3 and 25 hours, preferably between 6 and 24 hours.

The invention relates to a carbobenzoxy deprotection reaction method and application, and belongs to the technical field of catalytic chemistry. The method comprises the following steps: dissolving a raw material Cbz epoxy in ethanol, carrying out high-temperature reflux stirring treatment, transferring the obtained product into a reaction kettle, adding Raney nickel, charging and discharging nitrogen to discharge air in the kettle, charging and discharging hydrogen again, keeping the final pressure of the hydrogen in the reaction kettle at 1-2 MPa, after the room-temperature reaction is finished, filtering the Raney nickel to obtain a reaction liquid, dripping the reaction liquid to crystallize, and carrying out suction filtration and drying to obtain the product. The filtered Raney nickel is recycled and reused for at least 10 times after being treated at a high temperature, and new Raney nickel is replaced, so that the triangular balance of'catalytic performance-economic cost-process stability 'is realized, the production cost is reduced on the premise of not influencing the reaction effect, the used Raney nickel is recycled and reused after being properly treated, and the production cost is reduced. And the production cost is further reduced, and good economic benefits are achieved.

The invention relates to the technical field of catalyst treatment, in particular to a Raney nickel catalyst reduction and passivation treatment system and a passivation method.The system comprises a deactivation pool, a hydrogenation reactor and a circulation pipeline which are connected in a closed loop mode; a sodium nitrate solution supply end, a temperature adjusting system and a multi-dimensional sensing assembly (a concentration sensor, a temperature sensor, a pH sensor, a pressure sensor, a flow sensor and the like) are arranged, and the core is a processing unit integrating a control module and a dynamic soft measurement model. The desalted water injection amount, the sodium nitrate solution concentration and the deactivation solution temperature are preset and dynamically optimized through the treatment unit, closed-loop circulation of a reaction system is achieved through a circulation pipeline, and the passivation process is judged based on the pH value change. According to the method, the passivation rate and the completion time are predicted by means of the dynamic soft measurement model, the optimal process parameters are output in a self-adaptive mode, and the problems that a traditional passivation method depends on artificial experience, and is low in safety and insufficient in efficiency are solved by combining a safety interlocking mechanism and a uniform mixing regulation and control strategy.

This invention provides a method for manufacturing electrode materials that have excellent water electrolysis performance in water electrolysis devices. [Solution] A method for manufacturing an electrode material used in the electrodes of a water electrolysis device includes a step of obtaining Raney nickel contained in the electrode material, and the step of obtaining Raney nickel includes an alkali treatment step of dissolving aluminum from the NiAl alloy with an alkaline substance. The component composition of the NiAl alloy, excluding unavoidable impurities, is the composition formula Al3Ni (2-x) Co x (x is 0

The application provides a high-porosity Raney nickel electrode and a preparation method thereof, and relates to the technical field of Raney nickel electrodes and preparation thereof. The preparation method of the high-porosity Raney nickel electrode effectively controls the dealuminization rate and the pore uniformity through a preparation process of'sintering treatment + special electrochemical dealloying treatment', and stably prepares the high-porosity Raney nickel electrode. A new process for preparing the high-porosity Raney nickel electrode in an environmentally friendly manner is provided, which replaces the traditional corrosion pore-forming process of a strong alkaline chemical solution and reduces pollution. The prepared high-porosity Raney nickel electrode has a high porosity of up to 52%, and the pore structure is stable, so that the catalytic activity and mechanical stability of the electrode are effectively improved.

This application discloses a method for preparing sodium dihydrobis(2-methoxyethoxy)aluminate, belonging to the field of organic synthesis technology. The method uses aluminum powder, ethylene glycol monomethyl ether, and metallic sodium as main raw materials, and carries out a hydrogenation reaction under the action of a Raney nickel catalyst to generate the target product, sodium dihydrobis(2-methoxyethoxy)aluminate. The sodium dihydrobis(2-methoxyethoxy)aluminate prepared by this process uses inexpensive and readily available raw materials, is simple to operate, and has a yield of over 98.5%. It boasts high yield, low cost, and a short process route, reducing production costs compared to existing technologies and making it suitable for industrial production.

This invention provides a method for manufacturing electrode materials that have excellent water electrolysis performance in water electrolysis devices. [Solution] A method for manufacturing an electrode material used in the electrodes of a water electrolysis device includes a step of obtaining Raney nickel contained in the electrode material, and the step of obtaining Raney nickel includes an alkali treatment step of dissolving aluminum from the NiAl alloy with an alkaline substance. The component composition of the NiAl alloy, excluding unavoidable impurities, is the composition formula Al3Ni (2-x) Cu x (x is 0)

The invention belongs to the field of fluorine-containing pesticide synthesis, and particularly relates to synthesis of fluopyram. The fluopyram is innovatively synthesized by adopting a one-pot catalytic system, and the reaction process is as shown in the formula 1: 2-acetonitrile-3-chloro-5-trifluoromethylpyridine (1) and o-trifluoromethyl benzoyl chloride (2) are used as initial raw materials, a catalyst with a specific structure and an alkali-binding acid agent are added into an ionic liquid, and a reaction is performed at the temperature of 60-80 DEG C for 1-2 hours to obtain the fluopyram. And preparing the target product fluopyram (3) by a high-efficiency one-pot method under the catalytic action of a supported metal catalyst in a hydrogen atmosphere. According to the one-pot synthesis process of fluopyram, the reaction is clean and pollution-free, the operation is simple and convenient, the utilization rate of raw materials is high, and the application frequency of Raney nickel can be increased under the condition that the yield is not influenced through a reaction system formed by combining water and an organic solvent. The o-trifluoromethyl benzoic acid recovered from the water phase can be further converted into o-trifluoromethyl benzoyl chloride, so that the utilization rate of the raw materials is improved. The synthesis process route is effectively shortened, and meanwhile, the use of expensive protection groups for protection in the hydrogenation reduction process is avoided, so that the process is more simplified.

The application discloses a method for synthesizing benoxacor, and belongs to the technical field of chemical organic synthesis. The method comprises the following steps: taking DMF as a solvent, fully reacting ortho-nitrophenol with monochloroacetone and alkali at a certain temperature, centrifuging after the reaction is completed, obtaining a first filter cake and a DMF solution of 2-nitro-2-phenoxypropanone, removing part of the DMF through vacuum distillation, detecting the content of chloroacetone in the gas chromatograph, and adjusting the mass concentration of the 2-nitro-2-phenoxypropanone DMF solution to 10-20% after the content of chloroacetone is detected to be lower than 0.02% by using the area normalization method; then, adding Raney nickel into the 2-nitro-2-phenoxypropanone DMF solution, and performing hydrogenation reaction by passing hydrogen; after the reaction is completed, the upper clear liquid is extracted, and 3,4-dihydro-3-methyl-2H-1,4-benzoxazine DMF solution is obtained through filtration; then, an acid-binding agent alkali is added, and acylation reaction is performed by dropwise adding dichloroacetyl chloride, so as to synthesize benoxacor. The method can greatly simplify the operation process of frequently changing solvents in the process of synthesizing benoxacor, and can avoid the generation of a large amount of waste brine.

The invention discloses vanillin alcohol ether and a preparation method thereof, and the preparation method comprises the following steps: (1) by taking vanillin or ethyl vanillin and hydrogen as reactants and alcohol or ethyl acetate (EA) as a solvent, preparing a reactant solution, adding a Raney nickel catalyst as a catalyst, and reacting at the temperature of 40-70 DEG C under the reaction hydrogen pressure of 2-3 MPa for 8-10 hours; and (2) by taking vanillin alcohol or ethyl vanillin alcohol and second alcohol as reactants and lewis acid (such as magnesium chloride, aluminum chloride, calcium chloride, ferric chloride, copper sulfate and other lewis acids) as a catalyst, reacting at 80-100 DEG C to obtain vanillin alcohol ethers, the preparation method disclosed by the invention is mild in reaction condition, few in by-products, green and environment-friendly, high in product yield and suitable for industrial production.

The invention provides a synthetic preparation method of 3, 3 '-diaminodipropylamine (DPTA), which is efficient, safe, low in cost and easy to industrially amplify. The method is realized through two-step reaction: firstly, preparing 18-22% ammonia water in a water phase system under the conditions that the temperature is controlled to be 40-50 DEG C and the pressure is less than or equal to 0.3 MPa, then dropwise adding acrylonitrile into the ammonia water for reaction under the conditions that the temperature is 60-65 DEG C and the pressure is less than or equal to 0.5 MPa to generate a high-purity DPTAm intermediate, and carrying out rectification dehydration to obtain a dehydrated synthetic liquid containing more than or equal to 95 wt% of DPTAm; then in a hydrogenation reaction, isopropanol is used as a solvent, Raney nickel is used as a catalyst, KOH or NaOH is used as an auxiliary agent, under the guarantee of nitrogen and hydrogen replacement, the DPTAm dehydrated substance is dropwise added at a constant speed for catalytic hydrogenation under the conditions of 80-85 DEG C and 2.2-2.6 MPa, and after the reaction is completed, desolvation, light component removal and rectification purification are performed to obtain the target product DPTA. According to the method, high-selectivity synthesis of DPTAm is achieved, generation of by-products is remarkably reduced, ammonia gas consumption and recovery cost are reduced, meanwhile, the hydrogenation process is optimized, the conversion rate and yield are improved, the DPTA content is larger than or equal to 96%, and the total yield is larger than or equal to 95%. The Raney nickel catalyst can be repeatedly used for more than 50 batches, has stable activity, greatly reduces the production cost, and is suitable for large-scale industrial application.

The invention provides a rare earth doped Raney nickel electrode, a preparation method and application. The preparation method comprises the following steps: roughening a conductive substrate; spraying and depositing the composite powder on the conductive base material by adopting a spraying process to obtain a coating conductive base material; the coating conductive base material is placed in an alkaline solution for activating treatment, and the rare earth doped Raney nickel electrode is obtained; wherein the composite powder comprises powder of nickel powder, aluminum powder and rare earth components. By introducing the rare earth component, the electronic structure of nickel can be improved, the conductivity and catalytic activity of the electrode are improved, and the hydrogen evolution overpotential is reduced. And the powder with different particle sizes forms a dense and uniform coating layer by layer through the spraying process, so that the corrosion resistance and the mechanical strength are enhanced. Complex equipment and high cost are not needed, the adding amount of rare earth elements is small, and the method is suitable for large-scale industrial production.

The invention belongs to the technical field of medicine synthesis, and discloses a preparation method of cinacalcet hydrochloride impurities. According to the preparation method, the safety of the operation process is high, risks caused by raney nickel use and high-pressure hydrogenation in the prior art route are effectively avoided, meanwhile, the yield and purity of the product both reach the high level, and the dual requirements for process safety and product quality are met.

The utility model belongs to the technical field of spraying, and particularly relates to a Raney nickel uniform spraying device which comprises a box body, first limiting sliding grooves are formed in the inner wall of the top and the inner wall of the bottom of the box body, first sliding blocks are arranged in the two first limiting sliding grooves, a first hollow pipe is connected between the two first sliding blocks, and a second hollow pipe is connected between the two first sliding blocks. A plurality of spray heads are connected to the first hollow pipe, each spray head is provided with a first one-way valve, fixing blocks are installed on one sides of ports of the upper first limiting sliding groove and the lower first limiting sliding groove, threaded rods are rotatably installed on the fixing blocks and the side wall of the box body in a matched mode, and the threaded rods penetrate through the first sliding blocks; one end of each of the two threaded rods is sleeved with a belt pulley; when the ceramic spraying device is used, the distance between the spraying head and the ceramic can be adjusted according to the ceramic of different sizes through the arrangement of the spraying head adjusting mechanism, so that the optimal spraying distance is achieved, the coating uniformity can be ensured through accurately adjusting the position of the spraying head, and the spraying quality is ensured.

The application provides a double-layer Raney nickel electrode, a preparation method and application. 3+ The preparation method of the double-layer Raney nickel electrode comprises the following steps: providing a conductive base material; immersing the conductive base material in a solution containing Fe ions to perform a surface uniform etching reaction, so as to obtain an iron modified conductive base material; loading a Raney nickel type alloy powder on the iron modified conductive base material, so as to obtain a composite conductive base material; immersing the composite conductive base material in an alkaline solution to perform an activation reaction, so as to obtain the double-layer Raney nickel electrode. The double-layer Raney nickel electrode prepared by the application has high stability and high catalytic activity, has a good effect in electrolysis of water to generate hydrogen, and has high generation efficiency. Moreover, the preparation method of the application is simple, convenient to operate, and suitable for industrial production.

The embodiment of the present application discloses a preparation method of nor-tropine alcohol. The method comprises the following steps: performing demethylation reaction on tropinone and chloroethyl chloroformate in the presence of a solvent, performing vacuum concentration and evaporation, and obtaining demethyltropinone; performing reduction reaction on the demethyltropinone and lithium tri-t-butoxyaluminum hydride in the presence of a solvent, and obtaining the nor-tropine alcohol. The present application adopts a new type of reducing agent lithium tri-t-butoxyaluminum hydride, which is safe, not sensitive to air and water, and simple in post-treatment, thus avoiding safety hazards from the source. The present application avoids the use of dangerous Raney nickel and does not need to use an autoclave, so that the production capacity is greatly improved. The present application performs the reaction under low-temperature conditions, is low in energy consumption, can effectively reduce production cost, and is moderate in reaction conditions, safe and simple in operation, and is conducive to large-scale industrial production.

The application provides a Raney nickel electrode and a preparation method and application thereof, and relates to the field of hydrogen production by electrolysis of water. An electrode substrate with a Raney nickel catalytic layer on the surface is subjected to heat treatment to obtain a heat-treated electrode; an alkali solution, an additive and the heat-treated electrode are mixed, activated, washed and dried to obtain the Raney nickel electrode; the volume concentration of oxygen in the heat treatment is gradually reduced until a low-oxygen atmosphere or an oxygen-free atmosphere, and the temperature is gradually increased. By introducing a controllable gradient heat treatment process before alkali activation, sufficient diffusion between Ni and Al is promoted to form a specific content stable Ni3Al phase, the Ni-Al synergistic structure in the Ni3Al phase can regulate the surface electronic structure to a certain extent, improve the distribution of active sites on the electrode surface, and improve the hydrogen evolution and oxygen evolution performance. In addition, while ensuring the integrity of the porous electrode skeleton structure, the alloying degree is improved.

The application discloses a method for preparing trimethylolamine by a continuous flow method, and comprises the following steps: mixing polyformaldehyde and alkali to obtain a mixed solution 1; mixing a nitromethane solution and the mixed solution 1 to form a reaction solution, and then introducing the reaction solution into a micro-channel continuous flow reactor to obtain a mixed solution 2 after reaction; adjusting the flow rates of the mixed solution 2 and hydrogen, and then mixing the gas-liquid mixture into a gas-liquid mixer at the inlet of a micro-packed bed continuous flow reactor, passing through a catalyst bed layer of the micro-packed bed continuous flow reactor to react, and then adjusting the temperature through a reactor heat exchange cavity of the micro-packed bed continuous flow reactor to obtain a crude product after reaction, and then performing post-treatment and purification to obtain a trimethylolamine product; and the catalyst comprises a supported Pd catalyst, a supported Ni catalyst or a Raney nickel catalyst. The preparation method of the application enables the solid catalyst to fully contact with the mixed solution 2 and hydrogen, compared with a conventional intermittent hydrogenation preparation method, the reaction time is shortened, the product purity is high, the safety is high, and the method is beneficial to industrialized scale production.

The invention relates to a method for preparing an amino compound from a nitrile compound, which is characterized in that Raney nickel is used as a catalyst, a dicyandiamide inhibitor is added, and the amino compound is prepared through the following reaction, r is a C1-10 alkyl group, a C2-10 alkenyl group, a C3-10 alkynyl group, a C6-20 aryl group, a C6-20 aryl-C1-10 alkyl group, a C6-20 aryl-C2-10 alkenyl group, a C6-20 aryl-C2-10 alkynyl group, a C6-20 heteroaryl-C1-10 alkyl group, a C6-20 heteroaryl-C2-10 alkenyl group and a C6-20 heteroaryl-C2-10 alkynyl group, wherein the alkyl group, the alkenyl group, the alkynyl group, the aryl group and the heteroaryl group are optionally substituted by one or more than two substituent groups selected from halogen, the C1-6 alkyl group and the halogenated C1-6 alkyl group.

The invention discloses a closed-loop preparation and recovery method of an alkaline electrolysis water electrode, and belongs to the technical field of electrochemistry. The method comprises the following steps: thermally spraying nickel-aluminum alloy powder on a nickel net substrate to prepare an electrode precursor, and activating with a sodium hydroxide solution to form the porous Raney nickel structure electrode. The method is characterized in that an internal circulation system is constructed, the aluminum-containing waste alkali liquid activated by an electrode and over-spraying alloy powder subjected to thermal spraying are combined for treatment, and aluminum is selectively leached; carbon dioxide is introduced into the aluminum-rich alkali liquor for carbonization decomposition, and a high-purity aluminum hydroxide product is separated out; carrying out causticization reaction on the carbonized sodium carbonate-containing mother liquor by using calcium oxide to regenerate a sodium hydroxide solution and a calcium carbonate byproduct; and finely adjusting the regenerated alkali liquor, returning to electrode production, and treating the nickel-rich solid to obtain regenerated nickel powder. According to the method, electrode production and material circulation are deeply coupled, near-zero emission closed loop of sodium, nickel, aluminum and calcium elements is achieved, and the aluminum resource product value and recycling economy are improved through the process of first carbonization and then causticization.

The invention provides a boron-doped Raney nickel electrode, a preparation method and application. The preparation method of the boron-doped Raney nickel electrode comprises the following steps: sequentially carrying out first electrochemical treatment and second electrochemical treatment on a Raney nickel electrode to obtain the boron-doped Raney nickel electrode, the first electrochemical treatment comprises the following steps: taking the Raney nickel electrode as a cathode, and carrying out electrochemical reaction in an alkaline solution; the second electrochemical treatment comprises the following steps: after the first electrochemical treatment is completed, adding a boron source into the alkaline solution, and continuously carrying out electrochemical reaction. The boron-doped Raney nickel electrode prepared by the invention has good chemical stability and long service life in a strong alkali environment; moreover, the method is simple in process and convenient to operate, reduces the production cost, improves the production efficiency, and is suitable for an industrial electrolytic cell production line.

The invention discloses an integral hierarchical porous reticular nickel catalyst as well as a preparation method and application thereof, and belongs to the technical field of chemical catalytic materials. According to the catalyst, a commercial nickel net is used as a supporting framework, and a porous nickel active layer with micron-level thickness is constructed on the surface of a nickel net wire, so that an integral structure with macro-mesoporous-micro hierarchical pore channels is formed. The preparation method comprises the following steps: burying the nickel net in mixed powder containing aluminum powder and an activating agent (aluminum chloride or ammonium chloride), and carrying out high-temperature roasting in an inert atmosphere to form a nickel-aluminum alloy layer on the surface of the nickel net; and then aluminum is removed through alkali liquor corrosion, and the monolithic catalyst with the raney nickel type porous structure on the surface is obtained. The catalyst has the advantages of excellent mass and heat transfer performance, high specific surface area, abundant active sites, simple preparation process and low cost. When the catalyst is applied to an adiponitrile hydrogenation reaction, high activity and high selectivity are shown. Assistants such as Fe, Cr, Mo, Co, Zn and the like can be introduced through post-modification, so that the performance is further improved.

This method for producing an electrode material used for an electrode of a water electrolysis device includes a step for obtaining Raney nickel contained in the electrode material. The step for obtaining Raney nickel includes an alkali treatment step for eluting aluminum from a NiAl alloy using an alkali substance. The component composition of the NiAl alloy, excluding inevitable impurities, is represented by the compositional formula Al3.00Ni(2.00 − (x + y))CuxFey (x and y are values satisfying 0.00 < x + y ≤ 0.45, 0.00 < x ≤ 0.40, and 0.00 < y ≤ 0.30).

This method for producing an electrode material used for an electrode of a water electrolysis device includes a step for obtaining Raney nickel contained in the electrode material. The step for obtaining Raney nickel includes an alkali treatment step for eluting aluminum from a NiAl alloy using an alkali substance. The component composition of the NiAl alloy, excluding inevitable impurities, is represented by the compositional formula Al3.00Ni(2.00 − x)Cux (x is a value satisfying 0.00 < x < 0.30).

The invention relates to a preparation method of a high-purity neohesperidin dihydrochalcone crystal, which comprises the following steps: dissolving neohesperidin with an alkaline solution, and adding acid and an alcohol solvent for crystallization and purification to obtain high-purity neohesperidin, the method comprises the following steps: reacting neohesperidin in the presence of an alkali solution, hydrogen, palladium on carbon or raney nickel to generate neohesperidin dihydrochalcone, adjusting the pH value, adding alcohol as a mixed solvent, and separating out at normal temperature to obtain high-purity neohesperidin dihydrochalcone; and recrystallizing with alcohol / methyl tertiary ether to obtain the neohesperidin dihydrochalcone crystal. According to the method disclosed by the invention, the problem of low purity of neohesperidin dihydrochalcone in the prior art is solved, and the obtained neohesperidin dihydrochalcone needle-shaped crystal is high in sweetness, long in sweet holding time, high in sweet abundance and long in residual sweet aftertaste.

The invention discloses a method for preparing a key intermediate of a medicine Alasset. According to the method disclosed by the invention, 6-bromine-7, 8-dihydronaphthalene-2-alcohol is taken as a raw material, and four-step reaction of etherification, coupling, nickel catalytic hydrogenation and ether bond breakage is carried out, so as to obtain the ilastrant intermediate N-(2-(6-hydroxy-1, 2, 3, 4-tetrahydronaphthalene-2-yl)-5-methoxyphenyl) acetamide. According to the method disclosed by the invention, trityl etherification of 2-position alcohol is carried out, and Raney nickel is adopted for catalytic hydrogenation, so that the use of an expensive palladium metal catalyst is avoided, the hydrogenation cost is reduced, and the method has the characteristics of high yield and convenience in post-treatment. The method has a large-scale application prospect.

The invention relates to the technical field of collagen peptides, in particular to a collagen peptide with an anti-aging effect and a preparation method and application thereof.The preparation method comprises the steps that wood frog skin powder is added into water, then protease is added for enzymolysis, obtained enzymatic hydrolysate is subjected to enzyme deactivation and centrifugation in a water bath, supernate is collected, the supernate is subjected to desulfurization in the presence of hydrogen and a catalyst, and the collagen peptide with the anti-aging effect is obtained; and after desulfurization is finished, separating out reaction liquid, and drying. According to the present invention, the collagen peptide finished product prepared by using the method has characteristics of extremely high quality and excellent oxidation resistance, and can be widely used in the fields of anti-aging cosmetics, health food and the like.

The application discloses a catalyst preparation method based on Raney nickel porous framework structure cooperation electrodeposition and electroactivation, adopts mechanical heat treatment technology to form a nickel-aluminum alloy layer on the surface of a nickel mesh, carries out chemical activation treatment in an alkali solution, selectively dissolves aluminum elements, and thus constructs a Raney nickel porous framework structure; then, a nickel-iron-molybdenum-copper multi-metal active catalytic layer is constructed on the surface of the nickel mesh through an electrodeposition technology; finally, the obtained nickel-based catalyst is placed in a phosphorus-containing alkaline electrolyte to carry out electroactivation treatment, in-situ structure reconstruction and surface chemical state transformation of the multi-metal active catalytic layer on the surface of the nickel mesh are induced, and the electrode catalytic performance is further improved, and the nickel-based catalyst has great application potential in the field of alkaline electrolytic water hydrogen production.