101 results about "Dihydrochalcone" patented technology

The present invention is directed to the use of one or more rebaudioside C polymorphs, or stereoisomers thereof, to enhance the sweet taste of a flavoring, such as glucosylated steviol glycoside, rebaudioside A, ammoniated glycyrrhizin, neohespherdin dihydrochalcone or thaumatin.

The invention discloses a making method of four new substituted phenyl flavonols (1-4) compound, eight new sesquiterpenoids (5-12), one new dihydrochalcone (13) and eight known compound (14-21), which contains drug composition with effective component of sarcandra glabra as well as the application in the liver-damage protecting drug.

The invention relates to a method for preparing a rod-like imprinted polymer capable of efficiently separating naringin in a water phase. The rod-like imprinted polymer which is an adsorption material having specific recognition capability for naringin organic molecular medicaments with =O and -OH groups can be prepared by an emulsion polymerization method, with the naringin, hesperidin, the naringin or dihydrochalcone as an imprinting molecules, cyclodextrin as a functive and hexamethylene diisocyanate as a cross-linking agent. The prepared rod-like imprinted cyclodextrin polymer has larger specific area and pore volume, benefits the contact of a substrate with a combined locus and improves the capacity. The rod-like molecular imprinted polymer (RMIP) has high affinity and selectivity to the naringin (NG). When the concentration of the NG is 0.02mg/ml, the imprinted molecule alpha reaches 1.53.

The invention relates to a preparation method of dihydrochalcone molecule imprinted solid phase extraction column filling material. In the method, reaction raw materials: template module dihydrochalcone, acrylamide, crosslinking agent ethylene glycol dimethacrylate are added to pore-foaming agent such as acetonitrile or chloroform, uniformed mixed, initiator azobisisobutyronitrile is added, degassed and filled with nitrogen before being sealed, and are reacted under the temperature of 40-80 DEG C for 20-48 hours to obtain coarse molecule imprinted polymer which is then grinded to granularity of 15-80 micro meters; soxhlet extraction is carried out by a mixed solvent of methanol and acetic acid; acetone is then used for deposition so as to remove fine grains and to obtain dihydrochalcone molecule imprinted polymer; the polymer is uniformly filled in the polypropylene cylinder so as to obtain the dihydrochalcone molecule imprinted solid phase extraction column, thus separating enriched dihydrochalcone from natural outcome simply and efficiently.

The invention discloses a hesperetin dihydrochalcone-7-O-glucoside, wherein the compound is obtained by generating a rhamnose deglycosylation reaction of new hesperidin dihydrochalcone in water or a water and organic solvent system under an enzyme action. The sweetness multiple of the hesperetin dihydrochalcone-7-O-glucoside prepared by the invention is about 1800 times of sucrose, and the hesperetin dihydrochalcone-7-O-glucoside can be widely used for industries of foods, medicines, feed, daily use chemicals and the like and used as a sweetening agent, a flavoring agent, a flavor enhancer and the like.

The invention discloses alpha-glucose-based new hesperidin dihydrochalcone. The compound is obtained by carrying out alpha-glucose-based reaction by using new hesperidin dihydrochalcone and dextrin as raw materials under the catalysis of glucosyltransferase. The alpha-glucose-based new hesperidin dihydrochalcone synthesized by the method can be widely used for the industries of foodstuff, medicaments, forages, daily chemicals and the like as a sweetener, a flavoring agent, a flavor enhancer and the like.

A method for production of a dihydrochalcone, especially of phloretin, using a transgenic microorganism, containing a nucleic acid section (a), comprising or consisting of a gene coding for a bacterial chalcone isomerase, and/or a nucleic acid section (a′), comprising or consisting of a gene coding for a plant chalcone isomerase, and a nucleic acid section (b), comprising or consisting of a gene coding for a bacterial enoate reductase, corresponding transgenic microorganisms, containing a nucleic acid section (a), comprising or consisting of a gene coding for a bacterial chalcone isomerase, and/or a nucleic acid section (a′), comprising or consisting of a gene coding for a plant chalcone isomerase, and/or a nucleic acid section (b), comprising or consisting of a gene coding for a bacterial enoate reductase, and host cells, containing one or more identical or different such vectors.

The invention discloses a Hubei caval vine general flavone extract which is prepared by the following method: firstly, using ethanol to extract; then using a macroporous resin column or a daiamid column to adsorb; using the ethanol to elute; and collecting the ethanol eluting liquid to carry out vacuum concentration or vacuum drying or spray drying or freeze drying so as to obtain the Hubei caval vine general flavone extract. The content of general flavone in the Hubei caval vine general flavone extract is more than 50 percent, and the total content of phlorizin of a dihydrochalcone compound and 3-hydroxybenzoate phlorizin is more than 40 percent, wherein the mass ratio of the phlorizin to the 3-hydroxybenzoate phlorizin is 20:1-5:1. The obtained Hubei caval vine general flavone extract has low toxicity and can be used for preparing medicaments for treating type II diabetes mellitus.

The invention provides an application of pinocembrin dihydrogen chalcone-7-O-[3'-O-galloyl-4',6'-hexahydroxydiphenodicarboxy]-beta-D-glucoside in preparation of a liver protection medicine. The penthorum chinense pursh macrocyclic polyphenol monomer namely pinocembrin dihydrogen chalcone-7-O-[3'-O-galloyl-4',6'-hexahydroxydiphenodicarboxy]-beta-D-glucoside has a liver protection effect, can be used for preventing and treating liver injuries, and has a definite curative effect on hepatic ischemia-reperfusion injuries and chronic liver injuries, and the effect is superior to that of positive medicine namely Gansu Granules, so that the penthorum chinense pursh macrocyclic polyphenol monomer can be used for replacing the Gansu Granules and has a good clinical application prospect.

The invention belongs to the technical field of plant extraction and analysis, and especially relates to a jujube root extract, an extraction and separation method and an application thereof. The jujube root extract includes the following 15 components: ursolic acid, ceanothenic acid, eugenol-beta-D-glucoside, dihydrochalcone-4'-beta-D-glucopyranoside, oleanolic acid, 3-oxooleanolic acid, catechin, betulinic acid, jujube naphthoquinone, spineless common jujube benzyl II, beta-sitosterol, stigmasterol, daucosterol, p-hydroxybenzoic acid, and quercetin. The method utilizes ethanol extraction andethyl acetate extraction, and combines the use of silica gel, CHP-20P, macroporous resin, Sephadex LH-20 and other column chromatography techniques to separate the jujube root extract, and can be applied to researches of drugs for delaying Alzheimer's disease and treating diabetes.

The invention discloses a method for preparing five compounds with anti-inflammation activities from oxytropis falcate bunge by separation. The five compounds include pinocembrin, 4-hydroxyl-2-methoxychalcone, 7-hydroxyflavanone, 2, 4-dihydroxyl-dihydrochalcone and 2, 4-dihydroxyl-chalcone. The method includes the steps: (1) taking total flavone extracts of the oxytropis falcate bunge, sequentially extracting by the aid of petroleum ether and ethyl acetate, and taking ethyl acetate portions; (2) taking ethyl acetate portion drying powder, purifying by the aid of a resin, eluting by the aid of methyl alcohol, drying eluting substrates to obtain purified substrates; (3) separating the purified substrates by a preparative chromatography to obtain the pinocembrin, the 4-hydroxyl-2-methoxychalcone, the 7-hydroxyflavanone, the 2, 4-dihydroxyl-dihydrochalcone and the 2, 4-dihydroxyl-chalcone. The method is large in preparation quantity, high in product purity and suitable for industrial application.

Compositions and consumables comprising certain sweeteners and at least one dihydrochalcone of Formula I are provided herein, wherein the at least one sweetener is selected from certain steviol glycoside and/or mogroside sweeteners in sweetening amounts. The at least one dihydrochalcone enhances the sweetness of the consumable and optionally modulates one or more taste attributes to make the consumable taste more like a sucrose-sweetened consumable. Methods of enhancing the sweetness of a consumable, methods of making a consumable taste more like a sucrose-sweetened consumable and methods of preparing consumables are also detailed herein.

The invention relates to a composition capable of promoting insulin secretion and inhibiting generation of advanced glycosylation end products. The composition comprises the following components in percentage by mass: 5-95% of proanthocyanidin extract and 5-95% of dihydrochalcone. The main component of the proanthocyanidin extract is proanthocyanidin which accounts for 50-70% of the mass of the extract. The composition lays a foundation for the production of the future compound medicines, is beneficial to controlling blood sugar of diabetics and preventing and treating diabetic complications. The composition of the invention has the advantage that the multifunctional synergistic effect is obviously superior to effect of each independently used component.

The invention relates to a food, foodstuff or edible composition comprising isomaltulose and acesulfame K or a blend of acesulfame K with one or more other High Intensity Sweetener (HIS). The invention further relates to a process for replacing a carbohydrate sweetener under retention of the sweetness and taste profile of the carbohydrate sweetener, which process comprises replacing the carbohydrate sweetener by a mixture comprising isomaltulose and acesulfame K or a blend of acesulfame K with one or more other High Intensity Sweetener (HIS). The invention also relates to a new mixture which comprises isomaltulose and a blend of acesulfame K with one or more other HIS selected from the group consisting of alitame, cyclamate, dihydrochalcone, io han go, neohesperidin, neotame, saccharin, steviosid, sucralose and thaumatin.

The invention discloses a dihydrochalcone-like compound (I) contained in tobacco and a preparation method and application thereof. The preparation method comprises the following steps: crushing a tobacco sample and then carrying out ultrasonic extraction by 70 percent of acetone for 3 times, merging extracting solutions, filtering and decompressing and concentrating the extracting solutions to a small volume, standing and then filtering deposits; extracting a filtrate by ethyl acetate for 3 times, and then obtaining partial extraction liquid of ethyl acetate; concentrating the extraction liquid into an extract, carrying out primary screen on the extract by silica gel column chromatography, and then adopting a high-efficiency liquid semipreparative chromatography for further separation, and then obtaining the required novel compound. Antioxidant activity and anti-HIV-1 activity screening is carried out on the compound, and an experimental result shows that the compound shows higher antioxidant activity and anti-HIV-1 activity.

The invention belongs to the technical field of sweeteners, and particularly relates to a novel zero-calorie sweetener and a preparation method thereof. The sweetener is prepared from the following raw materials in parts by weight: 90-99.8 parts of erythritol, and 10-0.2 parts of neomethyl hesperidin dihydrochalcone. The novel zero-card sweetener disclosed by the invention has the advantages of attractive crystal, high sweetness selectivity, no heat, and high yield, is simple and easy to obtain, is widely used in coffee and hot drinks, and can also be used as table sugar at a restaurant or athome; both erythritol and neomethyl hesperidin dihydrochalcone are naturally extracted sweeteners, and have no calories, so this product does not cause blood sugar changes in a consumer, does not produce heat, and can be used as a zero-calorie sweetener.

The invention discloses a method for high-throughput analysis of plant secondary metabolites based on LCMS. A Scheduled-MRM mode is adopted to realize one-needle sample injection within 45min. Meanwhile, 130 types of plant secondary metabolites including anthocyanidin, benzoic acid and derivatives thereof, catechin and derivatives thereof, coumarin and derivatives thereof, dihydrochalcone, flavanone, flavone, flavonol, isoflavone, phenylpropanoids, procyanidine, stilbene, terpenes and the like are subjected to high-throughput absolute quantitative analysis. The method is high in pretreatment extraction efficiency, an instrument analysis method is wide in linear range, and high-abundance and low-abundance secondary metabolites with a large content difference can be detected and analyzed atthe same time; linear correlation is good, and a correlation coefficients are all higher than 0.995; the quantification limit of partial substances is as low as 0.01 ng/mL, and the sensitivity of themethod is high; accuracy is 80.2%-118.2%, and precision is 0.7%-119.9%; and high throughput and method sensitivity can be considered through Scheduled-MRM scanning, and the method can be widely applied to analysis of secondary metabolites in different complex plant samples.

The invention provides a pig used sweet additive-solid dispersion instant saccharin sodium microcapsule additive and the preparation method thereof. The solid dispersion instant saccharin sodium microcapsule additive is made of the following raw materials being dissolved in water and being spray dried: 100 to 200 parts of saccharin sodium by quantity, 0.2 to 10 parts of synergistic agent by quantity, and 1 to 5 parts of flavor by quantity; the synergistic agent adopts one of the followings or the mixture of the two or more than two: (1) new Hesperidin dihydro chalcone, (2) sodium chloride and (3) sodium glutamate. The invention ensures that each saccharin sodium particle contains identical content of synergistic agent, and the microcapsule is thin enough, and has the advantages of rapid dissolving and good palatability, on one hand, the microcapsule being spray dried has good fluidity, on the other hand, because the number of the particles is from 75 to 80 million, the uniform distribution of the saccharin sodium products in feed product can be ensured, and in addition, because the flavor is added, the feed attracting function is provided. The invention is suitable for being added to pig feed, in order to enhance the palatability of the feed and promote the growth of the pig, as well as the invention has good application prospect.

The invention belongs to the technical field of sweeteners, and particularly relates to a preparation method of a novel compound sweetener. The preparation method of the novel compound sweetener comprises the following steps: mixing a sweet carrier, neotame, cyclamate and hesperidin dihydrochalcone-7-O-glucoside according to a certain mass ratio, and dissolving with purified water at a low temperature to prepare a sugar solution; heating the sugar solution obtained in the step (1) to the temperature of 60-70 DEG C, and adding diglyceride or citric acid to enable the pH value of the sugar solution to be 1-6; and cooling to the temperature of 0-20 DEG C, crystallizing for 24-48 h, and drying to obtain the novel compound sweetener. The preparation method of the novel compound sweetener provided by the invention is reasonable in compound, the sweet taste has a creamy taste, the sweet taste is pure, the cost is not high, the novel compound sweetener can be used as a sweetener, a flavoring agent or a flavoring agent, and the novel compound sweetener can be widely applied to products such as foods, medicines, feeds and daily chemicals.