75 results about "Decane" patented technology

The invention relates to a preparation method of (R)-3-amino-1-oxa-8-azaspiro [4.5] decane-8-carboxylic acid tert-butyl ester, which comprises the following steps: carrying out Grignard reaction on N-BOC-4-piperidone and allyl magnesium halide to obtain an intermediate 1; carrying out substitution reaction on the intermediate 1 and 3-halogenated propylene to obtain an intermediate 2; performing olefin metathesis reaction on the intermediate 2 under the action of a Grubbs catalyst to obtain an intermediate 3; carrying out nitration reaction on the intermediate 3 and nitric acid to obtain an intermediate 4; carrying out hydrogenation reduction reaction on the intermediate 4 to obtain a racemic intermediate 5; and carrying out chiral resolution on the intermediate 5 by using a resolving agent to obtain a target product. The preparation method provided by the invention is short in process route and simple to operate, does not generate a large amount of waste water and waste gas, and can achieve higher total product yield and chemical and chiral purity.

The invention discloses an ionic liquid modified nano calcium carbonate / dipropyl aluminum hypophosphite flame-retardant nylon material, and relates to the technical field of flame-retardant materials, the ionic liquid modified nano calcium carbonate / dipropyl aluminum hypophosphite flame-retardant nylon material comprises, by weight, 68-85 parts of nylon 6 slices, 0.1-0.5 part of an antioxidant, 0.2-1 part of a lubricant, 10-25 parts of dipropyl aluminum hypophosphite, and 5-10 parts of ionic liquid modified nano calcium carbonate; wherein the ionic liquid modified nano calcium carbonate is obtained by mixing, dispersing and drying nano calcium carbonate and ionic liquid; the ionic liquid is prepared from 1-methyl-1H-imidazole, decane chloride and NaBF4 (NaBF4). The environment-friendly flame-retardant cable material has the effects of environment friendliness, efficient flame retardance and low cost.

The invention relates to a catalyst for the selective reduction of NOx, based on an IZM-10 AEI zeolite and at least one transition metal, and to its preparation method comprising at least mixing, in an aqueous medium, a FAU-type zeolite having a SiO2 (FAU) / AI2O3(FAU) molar ratio of between 10 and 60 inclusive and a mass percentage of sodium in cation form of less than 0.005%, a nitrogen-containing organic compound R, wherein R is (6R,10S)-6,10-dimethyl-5-azoniaspiro[4,5]decane in its hydroxide form, and optionally sodium hydroxide, until a homogeneous precursor gel is obtained; ii) a hydrothermal treatment step; iii) a step of exchanging at least one ion with a solution comprising at least one species capable of releasing a transition metal; iv) a heat treatment step by drying and calcination.

The invention belongs to the technical field of polyurethane elastomers, and particularly relates to a colorless transparent polyurethane elastomer and a preparation method thereof. The invention provides a colorless transparent polyurethane elastomer. The colorless transparent polyurethane elastomer is prepared from the following raw materials: polyalcohol, isocyanate, a chain extender and a catalyst, the isocyanate comprises an alicyclic isocyanate and / or an aliphatic isocyanate; the chain extender is tricyclic [5.2. 1.0 (2, 6)] decane dimethyl carbinol. In the invention, ring [5.2. 1.0 (2, 6)] decane dimethyl carbinol (TDDM) with an asymmetric alicyclic structure is used as a chain extender, and the high steric hindrance effect of the ring [5.2. 1.0 (2, 6)] decane dimethyl carbinol (TDDM) is utilized to form a synergistic effect with alicyclic (or aliphatic) isocyanate, so that the crystallization of a hard segment in the polyurethane elastomer is inhibited, the size of an ordered region is reduced, and the wear resistance of the polyurethane elastomer is improved. Therefore, the polyurethane elastomer provided by the invention has excellent mechanical properties on the basis of meeting colorless and transparent requirements.

The application discloses a preparation method of an important intermediate of a pyrimidine-4(3H)-ketone heterocyclic compound shown in formula h, namely a preparation method of (3S,4S)-tert-butyl 4-((R)-1,1-dimethylethylsulfinamido)-3-methyl-2-oxa-8-azaspiro[4.5]decane-8-carboxylate, which is synthesized through a series of reactions such as substitution, reduction, nucleophilic addition, reduction and deprotection, ring closure, oxidation and reductive amination and the like by taking L-methyl lactate as a raw material. In the application, red aluminum is used to replace lithium borohydride and tetrabutylammonium fluoride in the prior art, so that the problems of the risk caused by the use of lithium borohydride and the difficulty in post-treatment caused by the use of tetrabutylammonium fluoride in the prior art are overcome, the reaction steps are shortened, and the post-treatment operation is simplified.

The invention belongs to the technical field of medicine synthesis processes, and particularly relates to a preparation method of high-yield and high-purity buspirone hydrochloride. According to the method, 8-(2-pyrimidinyl)-8-aza-5-5-azonium spiro [4.5] decane hydrobromide (pyrimidino piperazine quaternary ammonium salt for short) and 3, 3-tetramethylene glutarimide are taken as raw materials, a mixed solvent of methylbenzene and n-amyl alcohol and / or n-hexanol is taken as a solvent, buspirone can be generated in the presence of sodium carbonate without adding a phase transfer catalyst, and buspirone can be obtained through acid adjustment and extraction. After toluene reverse phase impurity removal, a water phase is adjusted to be alkaline, an ethanol solution of hydrogen chloride is added after toluene extraction, and buspirone hydrochloride solid is directly separated out. The preparation process has a very good cleaning effect on impurities, and the obtained buspirone hydrochloride is high in purity, high in process yield, good in atom economy and low in output of three wastes.

The invention relates to a two-component dual-curing submarine cable water-blocking pouring sealant, which is composed of a component A and a component B according to a mass ratio of 1: 0.3-1, the component A comprises tricyclodecane modified hydroxyl-terminated polybutadiene, tertiary carbonate epoxy acrylate, polybutadiene, an acrylate-silicon dioxide nano composite material and a silane coupling agent, and the component B comprises a component C, a component D and a component E according to a mass ratio of 1: 0.3-1. A catalyst, a photoinitiator, an antioxidant, a defoaming agent and a polymerization inhibitor; the component B is prepared from an organic silicon modified dual-curing prepolymer, isocyanate and polybutadiene. The dual-component dual-curing submarine cable water-blocking pouring sealant can be subjected to UV and polyurethane dual curing, has excellent flowability and infiltration permeability, can be used for quickly and completely filling even a narrow gap, does not empty, does not generate a bubble defect, has high dual curing efficiency, and has relatively good water-blocking performance, electrical insulation performance and excellent high and low temperature resistance; long-term use reliability is stable, and submarine cables are effectively protected from seawater erosion.

The application relates to the technical field of catalysts, in particular to a Pickering emulsifier silica nanonet and a preparation method and application thereof. The preparation method comprises the following steps: dissolving cetyltrimethylammonium chloride in water, uniformly mixing, and adjusting the pH to 10; placing the cetyltrimethylammonium chloride solution in a water bath, adding an ethyl silicate n-decane solution, carrying out reaction after homogenization emulsification, and cooling, suction filtering, washing, drying, crushing to obtain the Pickering emulsifier silica nanonet. The Pickering emulsifier silica nanonet preparation method is simple and can be mass-produced. The degradation efficiency of polyester is high, and a high alcoholysis efficiency can be achieved at a lower reaction temperature and in a very short reaction time.

The invention relates to the technical field of polyimide film preparation, in particular to a preparation method of a high-toughness polyimide nanofiber film. The preparation method comprises the step of synthesizing polyamide acid, and further comprises the step of regulating and controlling the properties of a spinning solution containing the polyamide acid, a mixed solvent adopted for regulating and controlling the properties of the spinning solution is selected from at least two of N, N-dimethylformamide, N, N-dimethylacetamide, N-methyl pyrrolidone, dimethyl sulfoxide, 1, 4-dioxane, methanol, ethanol, methylbenzene, chloroform, tetrahydrofuran, normal hexane, normal heptane and normal decane. The breaking strength of the film can reach 30 MPa, the elongation at break can reach 60%, various diamine and dianhydride monomers and solvent systems can be prepared through the method, the mechanical performance is improved, the preparation technology is wide in application range, and the polyimide film prepared through the method can be used for oil-water separation and has the recycling and hot oil separation capacity.

The invention provides a caged alkane structure fuel, a preparation method thereof and an aerospace fuel, and belongs to the technical field of liquid fuels. The cage-shaped alkane structure fuel provided by the invention is 3, 8-dimethyl pentacyclic [5.3. 0.02, 5.03, 9.04.8] decane, and has two four-membered rings and four five-membered rings, and molecules have higher tension energy; the polyhedral oligomeric alkane structure fuel provided by the invention has a branched chain, the introduction of the branched chain can reduce the intermolecular acting force, increase the flexibility of molecules and improve the low-temperature performance of polyhedral oligomeric alkane, so that the polyhedral oligomeric alkane structure fuel has high specific impulse and better low-temperature performance while the density is not lower than 0.960 g / cm < 3 > and the net mass calorific value is not lower than 42.63 MJ / kg. Results of the embodiment show that the polyhedral oligomeric alkane structure fuel provided by the invention has high density and high calorific value, and the problem that liquid fuel is difficult to have high density and high calorific value at the same time is solved.

The invention belongs to the technical field of energy, and in particular relates to a biological blended fuel which comprises the following components: methyl palmitate, octadecane-9. 12-dienoic acid methyl ester, cis-11-octadecenic acid methyl ester, 2-methyl undecane, 3-methyl undecane, 3, 6-dimethyl decane, 3.7-dimethyl decane, 3, 8-dimethyl-undecane, 3, 8-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, 6-dimethyl decane, 3, the preparation method comprises the following steps: adding 1, 10-methyl eicosane, 2, 5-dimethyl dodecane, 5-methyl tridecane, 4-methyl-tridecane, 2-bromododecane, 3-methyl-5-propyl nonane, 3-methyl-tetradecane, n-nonane, 6-methyl undecane, 2, 5-dimethyl decane, C16H34, 5-methyl-tetradecane, 7-methyl heptadecane, 4-methyl tetradecane, 3-methyl-tetradecane and 2.5-dimethyl tridecane into a reaction kettle; methyl tetradecane, n-pentadecane and tetradecane; according to the invention, 10-methyleicosane and 5-methyltetradecane are used for providing a high volume calorific value, and the flame temperature is improved compared with that of common biodiesel.

Disclosed is a composition for cleaning and regenerating the hydrophobicity of the surface of a transparent polymeric material of high optical quality, characterized in that it comprises 20% to 40% by weight of a first liquid mixture of 0.2% to 3% by weight of paraffin and 97% to 99.8% by weight of a petroleum solvent that lies between heptane and decane, and 50% to 85% by weight of a second liquid mixture of 0.2% to 8% by weight of a surfactant having a molecular weight at most equal to 150 g / mol, 2-butoxyethanol, and 4% to 15% by weight of ethanol, the remainder to 100% being water; a method for cleaning and regenerating the hydrophobicity of the surface of a transparent polymeric material of high optical quality by means of this composition.

The invention relates to a preparation method of a drug intermediate azaspiro [4.5] decane derivative, and belongs to the technical field of drugs and chemistry. The invention provides a preparation method of a drug intermediate azaspiro [4.5] decane derivative shown as a formula 3. The reaction is as follows: # imgabs0 # comprises the following steps: step 1, reacting a compound shown as a formula 1 with a phosphorus reagent in the presence of alkali to obtain a compound shown as a formula 2; and step 2, obtaining a compound shown in a formula 3 from the compound shown in the formula 2 under the action of trichloroacetic acid and a halogenated alkane solvent. The method provided by the invention has the advantages of good selectivity, good reproducibility, short time consumption, economy and high conversion rate, is suitable for industrial production, and thus has good market value and profound practical significance.

The invention relates to a catalyst for the selective reduction of NOx, based on an IZM-10 zeolite of AEI structural type and at least one transition metal and its preparation process comprising at least the mixing in aqueous medium of a zeolite of FAU structural type having a SiO2 (FAU) / Al2O3 (FAU) molar ratio of between 10 and 60, limits included and a mass percentage of sodium in cationic form of less than 0.005%, of a nitrogenous organic compound R, R being (6R,10S)-6,10-dimethyl-5-azoniaspiro[4,5]decane in its hydroxide form and optionally sodium hydroxide, until a homogeneous precursor gel is obtained; ii) a hydrothermal treatment iii) at least one ion exchange with a solution comprising at least one species capable of releasing a transition metal iv) a heat treatment by drying and calcination. Figure to be published: Figure 2

The invention relates to a novel salt of 8, 8-difluoro-3-(2-(4-(4-methylpyridazine-3-yl) phenyl)-2-oxoethyl)-1, 3-diazaspiro [4.5] decane-2, 4-dione, and a preparation method of the novel salt. More specifically, the present invention relates to a benzene sulfonate salt (BSA-salt). The invention also relates to a preparation method of a composition containing the salt and application of the salt.

The present invention belongs to the technical field of polyurethane elastomers, and specifically relates to a colorless and transparent polyurethane elastomer and a preparation method thereof. The present invention provides a colorless and transparent polyurethane elastomer, and the preparation raw materials include polyols, isocyanates, chain extenders and catalysts; the isocyanates include alicyclic isocyanates and / or aliphatic isocyanates; the chain extender is tricyclo[5.2.1.0(2,6)]decanedimethanol. In the present invention, cyclo[5.2.1.0(2,6)]decanedimethanol (TDDM) with an asymmetric alicyclic structure is used as a chain extender, and its high steric effect is utilized to form a synergistic effect with alicyclic (or aliphatic) isocyanates, thereby inhibiting the crystallization of the hard segment in the polyurethane elastomer and reducing the size of the ordered region, thereby making the polyurethane elastomer provided by the present invention have excellent mechanical properties on the basis of meeting the colorless and transparent requirements.

The present invention relates to a process for the synthesis of the anti-haemorrhagic agent (R)-N-hydroxy-2-((4-(4-(methylcarbamoyl)phenoxy)phenyl)-sulfonyl)-8- azaspiro[4.5]decane-2-carboxamide and intermediates thereof. The invention also relates to a process for the preparation of a synthetic intermediate of said anti- haemorrhagic agent, (R)-8-(tert-butoxycarbonyl)-2-((4-fluorophenyl)sulfonyl)-8- azaspiro[4.5]decane-2-carboxylic acid and intermediates thereof.

The invention relates to the field of synthesis of drug intermediates, in particular to a preparation method of 3-oxo-1-oxa-8-azaspiro [4.5] decane-8-tert-butyl formate. The preparation method comprises the following steps: carrying out condensation reaction on a compound III (4-ethoxycarbonyl methylene-1-tert-butyl piperidinecarboxylate) and methyl glycolate to generate a five-membered ring, and preparing to obtain a compound IV; according to the preparation method, tert-butyl 3-oxo-1-oxa-8-azaspiro [4.5] decane-8-formate (compound I) is prepared through a decarboxylation reaction of the compound IV, and the total yield of the reaction can reach 88.73%. The preparation method provided by the invention has the advantages of easily available raw materials, simple operation and high reaction yield.

The present invention relates to 3(4),8(9)-bisformyltricyclo[5.2.1.0 2,6 According to the present invention, a separate catalyst recovery step is not required, and 3(4),8(9)-bisformyltricyclo[5.2.1.0]decane can be produced with high conversion and purity. 2,6 ] decane (TCDDA) can be produced.

The invention belongs to the technical field of azaspiro structure compound synthesis. The method is easy and convenient to operate, only a reaction substrate and a solvent are needed, oxygen in air serves as an oxygen source, and an oxidizing agent, a metal catalyst and the like do not need to be additionally added. Visible light is utilized to promote uniform cracking of diselenide, and selenium-based free radicals are the key of the reaction. The target product simultaneously contains a selenium and spiro bifunctional skeleton. The invention provides a synthesis method of phenylseleno-substituted 4-azaspiro [4.5] decane. The synthesis raw materials are an N-(4-methoxyphenyl)-N-(benzenesulfonyl) methacrylamide derivative and a diphenyl diselenide derivative. The synthesis method comprises the following steps of: synthesizing 4-azaspiro [4.5] decane, the reaction equation of the synthesis is shown in the specification.

The present disclosure relates to a method for preparing a 9-(pyridine-2-yl)-6-oxaspiro[4.5]decane derivative. Specifically, the method comprises reacting a compound A with (1 S ,4 S The preparation reaction of )-4-ethoxy-1,2,3,4-tetrahydro-1-naphthylamine forms an amide compound, which is then reduced to form an oxaspirocyclic derivative. The process has a short process route and a high yield, and is suitable for industrial production.

To provide high refractive index, high abbe compositions.SOLUTION: A composition is prepared by free radical polymerization of a reactive monomer mixture. The reactive monomer mixture comprises at least one hydrophobic monomer, at least one hydroxyl-containing monomer, at least one tricyclo[5.2.1.02,6]decanedimethanol di(meth)acrylate, and at least one polyamide. The reactive monomer mixture comprises at least one polyamide in an amount of about 0.10 wt.% to about 5.0 wt.%.SELECTED DRAWING: None

Composition comprising: a first component, which is tricyclodecanedimethanol, and a second component, wherein, when the composition is characterized in gas chromatography, the tricyclodecanedimethanol is eluted at a retention time in the range of 12.4 minutes to 13 minutes, the second component is eluted at a retention time in the range of 11.8 minutes to 12.4 minutes, each indicated by elution peaks at corresponding retention times in a spectrum, and the ratio of the area of ​​the elution peaks indicating the second component compared to the area of ​​the elution peaks indicating the tricyclodecanedimethanol is between 0.001:1 and 0.04:1.

The invention relates to the technical field of insulating cleaning agents, and provides an environment-friendly insulating cleaning agent which comprises an alkane hydrocarbon solvent, a nonionic surfactant, polysiloxane and an inorganic nano functional additive. Wherein the weight percentage of the alkane hydrocarbon solvent is at least 96%, and the alkane hydrocarbon solvent only comprises decane, undecane, dodecane and tridecane. According to the cleaning agent, the alkane hydrocarbon solvent containing four substances is matched with the nonionic surfactant, the polysiloxane and the inorganic nano functional additive, so that the insulation breakdown voltage, the volume resistivity and the open flash point can be improved at the same time under the condition of not containing any environment-unfriendly component; and hot-line work dangers can be effectively prevented. In addition, the cleaning agent not only realizes environment-friendly performance, but also has excellent natural volatility.

The present invention describes the gold-catalyzed construction of geminocyano-substituted tricyclic [4.4.0.0] 1,5 The method for synthesizing the decane skeleton belongs to the field of organic synthesis technology. Compound 1 is added to an organic solvent, and the reaction is carried out at 25℃-80℃ for 3 hours in the presence of a gold catalyst and additives to obtain product compound 2. The gold catalyst is selected from triphenylphosphine monochloride, triphenylphosphine gold(I) 3-methylbenzotriazole salt, and triphenylphosphine gold(I) trifluoromethanesulfonate. The additive is selected from silver trifluoromethanesulfonate, silver fluoroantimonate, and silver bis(trifluoromethanesulfonylimide). The synthetic method described in this invention is simple to operate, low in cost, highly efficient, and widely applicable, possessing practical application value. Substrate 1 in this invention can be flexibly derivatized by adjusting the structure of its synthetic raw materials or through subsequent functionalization modifications, providing greater convenience for skeleton modification. This invention utilizes the properties of gold catalysts to achieve rapid and convenient synthesis of fused-ring skeletons containing three-membered rings that are difficult to synthesize under other conditions.

Compositions and coatings for thin films designed to protect surfaces and windows from environmental abrasion (e.g., sand, dust, and rubbing) that are transparent in visual and infrared wavelengths are disclosed. The compositions comprise thiol-containing copolymers comprising: (1) 10-(3-butyl-2-hexyl-6-(9-mercaptononyl)cyclohexyl)decane-1-thiol; and (2) a multifunctional terminally unsaturated hydrocarbon monomer; wherein (1) and (2) are combined to form a UV curable crosslinked thermoset polymer network and no particulate fillers are added to the composition. The films exhibit a specular transmission of greater than 70% in the visual spectrum at about 400-700 nm, and IR wavelengths at about 4-5 µm, and about 7.5-12 µm when applied to a surface of a substrate in a coating thickness of about 1-500 µm. A method for making the films involving an UV initiated thiol-ene curing mechanism is also provided.

The application belongs to the technical field of medicine synthesis process, and particularly relates to a preparation method of high-yield and high-purity buspirone hydrochloride. The application takes 8-(2-pyrimidyl)-8-azido-5-5-azospiro[4.5]decane hydrobromide (referred to as pyrimidine piperazine quaternary ammonium salt) and 3,3-tetramethylene glutarimide as raw materials, takes a mixed solvent of toluene, normal pentanol and / or normal hexanol as a solvent, does not need to add a phase transfer catalyst, and can generate buspirone in the presence of sodium carbonate. After acid adjustment and extraction, toluene is removed in the reverse phase, the water phase is adjusted to be alkaline, toluene is extracted, hydrogen chloride ethanol solution is added, and buspirone hydrochloride solid is directly precipitated. The preparation process has a good removal effect on impurities, the obtained buspirone hydrochloride has high purity, high process yield, good atomic economy and small three-waste output.

The invention relates to a method for preparing an IZM-10 AEI zeolite comprising at least mixing, in an aqueous medium, a FAU-type zeolite having a SiO2 (FAU) / Al2O3 (FAU) molar ratio of between 10 and 60 inclusive and a mass percentage of sodium in cation form of less than 0.005%, a nitrogen-containing organic compound R, wherein R is (6R,10S)-6,10-dimethyl-5-azoniaspiro[4,5]decane in its hydroxide form, and optionally sodium hydroxide, followed by a step of hydrothermally treating the precursor gel obtained at the end of step i). The invention also relates to the AEI zeolite having a SiO2 / Al2O3 molar ratio of between 10 and 60 inclusive having a purity of greater than or equal to 98% by weight, preferably greater than or equal to 99% by weight, in partially or completely protonated form, obtained using the method.

Compositions and coatings for thin films designed to protect surfaces and windows from environmental abrasion (e.g., sand, dust, and rubbing) that are transparent in visual and infrared wavelengths are disclosed. The compositions comprise thiol-containing copolymers comprising: (1) 10-(3-butyl-2-hexyl-6-(9-mercaptononyl)cyclohexyl) decane-1-thiol; and (2) a multifunctional terminally unsaturated hydrocarbon monomer; wherein (1) and (2) are combined to form a UV curable crosslinked thermoset polymer network and no particulate fillers are added to the composition. The films exhibit a specular transmission of greater than 70% in the visual spectrum at about 400-700 nm, and IR wavelengths at about 4-5 μm, and about 7.5-12 μm when applied to a surface of a substrate in a coating thickness of about 1-500 μm. A method for making the films involving an UV initiated thiol-ene curing mechanism is also provided.