27 results about "Methyl carbamate" patented technology

The invention discloses an anti-yellowing PVB (Polyvinyl Butyral) adhesive for laminated glass and a preparation method thereof, and relates to the technical field of adhesives. The yellowing-resistant PVB glue for the laminated glass has the advantages that the yellowing resistance is high; the modified PVB / nano silicon dioxide composite material is prepared from the following raw materials in parts by weight: 55 to 65 parts of modified PVB resin, 4 to 6 parts of modified nano silicon dioxide, 15 to 20 parts of dioctyl adipate, 0.5 to 1 part of a compound antioxidant, 0.3 to 0.8 part of an ultraviolet absorbent UV-327, 0.2 to 0.5 part of a silane coupling agent KH-560, 0.3 to 0.6 part of ethylene bis stearamide, 0.1 to 0.3 part of 2-benzimidazole methyl carbamate, 3 to 5 parts of tris (1-chloro-2-propyl) phosphate and 0.1 to 0.3 part of nano titanium dioxide. 5 to 8 parts of isopropanol; 0.8 to 1.2 parts of polycarbodiimide. The special modified PVB resin and the nano silicon dioxide are matched with the auxiliary agents such as the compound antioxidant, the anti-yellowing performance of the PVB glue for the laminated glass is remarkably improved through precise process preparation, the components have a synergistic effect, the process is controllable, the product performance is stable, and the cohesiveness is good.

The invention relates to the technical field of waste asphalt regeneration, and particularly discloses a waste asphalt regenerant, large-proportion waste asphalt containing the waste asphalt regenerant and a preparation method of the waste asphalt regenerant and the large-proportion waste asphalt. The waste asphalt regenerant is prepared from the following raw materials: 45 to 55 percent of epoxidized illegal cooking oil, 15 to 20 percent of furfural refined oil, 8 to 12 percent of methyl carbamate, 3 to 5 percent of nano mica powder, 10 to 15 percent of desulfurized rubber powder and 5 to 8 percent of SEBS (Styrene-Ethylene-Butylene-Styrene) modifier. The waste asphalt regenerant has a three-dimensional network structure which is subjected to polar bonding; the large-proportion waste asphalt is prepared from the following components in parts by mass: 70 to 90 parts of waste asphalt, 15 to 25 parts of limestone sand, 10.5 to 18 parts of waste asphalt regenerant, 1 to 5 parts of new asphalt and 0.05 to 0.15 part of long-chain aliphatic hydrocarbon warm mixing agent. The regenerant can act in molecules of the waste asphalt, a stable space structure with elasticity and a three-dimensional network is formed through the synergistic effect of multiple components, and good low-temperature crack resistance and performance stability are kept after the waste asphalt is regenerated through the chemical bond effect among the components.

The invention belongs to the technical field of pharmaceutical analysis, and discloses a method for determining two potential genotoxic impurities in carbon [13C]-urea by gas chromatography. Comprising the following steps: (1) preparing a sample solution; (2) preparing a reference solution; (3) taking nitrogen as carrier gas, and detecting by adopting a medium-polarity or weak-polarity chromatographic column separation system; and (4) calculating by a peak area through an external standard method to obtain the accurate contents of methyl carbamate and ethyl carbamate in the carbon [13C]-urea. The method disclosed by the invention is simple to operate, good in specificity, linearity, precision and accuracy and high in sensitivity, and can realize accurate detection of residual potential genotoxic impurities, namely methyl carbamate and ethyl carbamate, in the carbon [13C]-urea.

This invention discloses a method for synthesizing methyl amino-methyl-phenylcarbamate compounds from p-toluidine. The method uses p-toluidine as a raw material, employs anhydrous zinc acetate catalyst and the green solvent dimethyl carbonate, to first prepare methyl p-toluylcarbamate, followed by one-step direct amination to prepare methyl 2-amino-4-methylphenylcarbamate and methyl 3-amino-4-methylphenylcarbamate. This invention has advantages such as readily available raw materials, an environmentally friendly reaction process, high atom utilization, and a first-step reaction yield of up to 96% and a second-step reaction yield of up to 35.7%.

This invention relates to the field of exhaust gas treatment technology, specifically disclosing an exhaust gas treatment device for methyl carbamate containing phosgene, including an alkaline scrubbing tower, an inlet pipe, and an outlet pipe. The alkaline scrubbing tower is equipped with multiple alkaline solution feed pipes. The bottom of the alkaline scrubbing tower is connected to a collection tank, which is connected to a treatment tank. A pusher head assembly is installed in the collection tank, and the pusher head assembly is connected to a pusher power assembly, which drives the pusher head assembly to move. After the pusher power assembly moves a certain distance, it pushes the discharge baffle to rotate upwards. At this time, wastewater accumulates near the discharge baffle under the pusher head assembly's influence. The wastewater then flows out from the gap between the discharge baffle and the inner wall of the collection tank. During this process, the gap must always be smaller than the wastewater level. Finally, the bottom plate of the pusher head assembly presses against the discharge baffle, sealing the drain outlet again. The exhaust gas inside the alkaline scrubbing tower can only be discharged from the drain outlet after mixing with the alkaline solution.

The utility model mainly relates to the technical field of tail gas treatment, and provides a methyl carbamate ammonia-containing tail gas treatment device which structurally comprises an operation support, a Roots blower is fixedly arranged at the bottom of the operation support, material grooves are fixedly formed in the front side and the rear side of the right end of the operation support respectively, and transition pipes are fixedly arranged at the bottoms of the material grooves. The bottom of the transition pipe is fixedly connected with a feeding port in the right end of the auger conveyor, methyl carbamate powder in the trough and the transition pipe is conveyed into the collecting barrel through the auger conveyor, the powder is raised and scattered in the collecting barrel, and the powder is conveyed through the auger conveyor and scattered in the collecting barrel. At the moment, the Roots blower is matched with the exhaust pipe, air exhaust treatment is carried out in the collecting barrel through the filter cartridge and the dust filtering cloth bag, and air in the collecting barrel is pumped into the dilute acid spraying kettle to be treated.

This invention discloses a method for preparing albendazole, belonging to the field of pharmaceutical preparation technology. The method includes: (1) cyclization reaction: using methyl cyanocarbamate and 4-(propylthio)phenyl-1,2-diamine or their hydrochloride as raw materials, reacting in water, methanol, ethanol or a mixed solvent in the presence of an acidic catalyst or an alkaline buffer; (2) crystallization and separation of crude product: adjusting the pH of the reaction solution to 3-5, and separating the solid and liquid to obtain the crude product; (3) washing and purification: the crude product is washed successively with toluene, methanol and water, and dried to obtain the purified product; (4) refining and post-treatment: dissolving, decolorizing and recrystallizing with a formic acid-water mixed solvent, drying, pulverizing and sieving, and packaging to obtain the finished product. This invention uses a green and environmentally friendly solvent system, suppresses side reactions through precise pH control, optimizes the three-stage washing and recrystallization process, achieves a molar yield of over 88%, a purity of 99.85%, meets pharmaceutical standards, and is suitable for large-scale production.

Fungicidal compositions comprising strobilurins The present invention relates to fungicidal compositions comprising at least one compound selected from the group consisting of (I-1) methyl N-[[5-[1-(2,6-difluoro-4-isopropyl- phenyl)pyrazol-3-yl]-2-methyl-phenyl]methyl]carbamate, (I-2) methyl N-[[5-[1-(4-cyclopropyl-2,6- difluoro-phenyl)pyrazol-3-yl]-2-methyl-phenyl]methyl]carbamate, (I-3) methyl N-[[5-[1-(4-chloro- 2,6-difluoro-phenyl)pyrazol-3-yl]-2-methyl-phenyl]methyl]carbamate, (I-4) methyl N-[[5-[1-[2,6- difluoro-4-(trifluoromethyl)phenyl]pyrazol-3-yl]-2-methyl-phenyl]methyl]carbamate, and as active component 2) at least one compound selected from the group consisting of (II-1) metarylpicoxamid, (II-2) fluoxytioconazole, (II-3) bifemetstrobin, (II-4) cyclobutrifluram or an N- oxide, or an agriculturally useful salt thereof, wherein the weight ratio of compound I to compound II is from 10:1 to 1:10. The invention also relates to an agrochemical composition comprising the composition and a solvent of solid carrier. Further, the invention relates to a non- therapeutic use of the inventive compositions controlling phytopathogenic harmful fungi.

The manufacturing method of the light-transmitting waterproof glue of the present invention includes: providing raw materials: acrylate, methyl carbamate, crosslinking agent, ultraviolet absorber, antioxidant and plasticizer; mixing the above raw materials evenly in proportion to form a viscous solution; and stirring, adjusting, extruding and roll-pressing the viscous solution to form the light-transmitting waterproof glue. This method is simple and low-cost, and the prepared glue has improved high light transmittance, excellent waterproof performance and strong adhesive force.

This invention relates to a method for the efficient preparation of methyl cyanurate, belonging to the technical field of pharmaceutical intermediate synthesis. The method includes the following steps: mixing 1-hydroxyethyl-3-methylimidazolium acetate with a 28-32% potassium phosphate aqueous solution at a mass ratio of (2.8-3.2):1, followed by allowing the mixture to stand and separate into upper and lower phases; adding a cyanamide aqueous solution to the lower phase; and continuously adding methyl cyanurate to the upper phase; stirring the reaction at 40-50°C for 1.5-2.5 hours; allowing the mixture to stand and separate into upper organic and lower brine phases; diluting the upper organic phase with 1.8-2.2 times its volume of deionized water, precipitating a solid, followed by filtration; collecting the filter cake and filtrate; washing and drying the filter cake to obtain methyl cyanurate. This invention achieves directional distribution of reactants, precise suppression of side reactions, and efficient separation of products by constructing a two-phase aqueous system.

The invention belongs to the technical field of medicines, and particularly relates to a group of butyrylcholine esterase (BChE) inhibitors with high selectivity and a screening method thereof, in particular to two BChE specific inhibitors, namely methyl 4-hydroxybenzyl carbamate and moringa seed extract, which are screened from a moringa seed extract. The invention also relates to application of the BChE specific inhibitor in preparation of drugs for preventing or treating Alzheimer's disease. The invention provides a brand new strategy for efficiently screening the anti-Alzheimer disease medicine.

This invention relates to a method for preparing compound (I) or a pharmaceutically acceptable salt or solvate thereof. In particular, such a method comprises the dehydration cyclization of a 1,2-diacylhydrazine intermediate to form the corresponding 1,3,4-oxadiazole, wherein the dehydration cyclizing agent may be N,N-dimethylaminosulfonyl chloride, N-(triethylammonium sulfonyl)carbamate, phosphorus trichloride, or phosphorus pentachloride, resulting in increased product yield and purity compared to known methods. Compound (I) and pharmaceutical compositions thereof can be used as respiratory syncytial virus (RSV) inhibitors.

The invention relates to a method for synthesizing 1, 5-naphthalene dicarbamate under the catalysis of cerium oxide. The method comprises the following steps: adding 1, 5-naphthalene diamine, dimethyl carbonate and a catalyst into a reactor, and carrying out stirring reaction for 5-10 hours in a nitrogen atmosphere at 150-180 DEG C under normal pressure to obtain 1, 5-naphthalene dicarbamate; wherein the catalyst is cerium oxide, and the addition amount of the catalyst is 40-80% of the mass of the 1, 5-naphthalene diamine; the molar ratio of the dimethyl carbonate to the 1, 5-naphthalene diamine is (30-68): 1. The method reduces the cost loss, is environment-friendly, does not generate toxic gas, chlorine-containing waste or catalyst waste liquid, is simple and convenient in operation process, and can recycle the catalyst for multiple times.

The invention relates to a method for synthesizing 4, 4 '-diphenylmethane dicarbamate by using dimethoxymethane as a methylenating agent. The method comprises the following steps: adding MPC, dimethoxymethane, a reaction solvent and a catalyst into a reactor, and carrying out stirring reaction for 2-6 hours under the conditions of N2 atmosphere and 90-200 DEG C to obtain MDC; the catalyst is sulfuric acid, dodecyl zinc sulfate or a solid catalyst. The method has the advantages of being high in reagent stability, few in by-products, more beneficial to reaction and the like.

The invention belongs to the technical field of organic chemical synthesis, and provides a cyclohexyl isocyanate synthesis process, which comprises: 1, adding cyclohexylamine and a catalyst A into a solvent, controlling the temperature at 0-5 DEG C, slowly dropwise adding dimethyl carbonate, maintaining the temperature at less than 10 DEG C, removing the ice bath after completing the dropwise adding, slowly heating to a room temperature, continuously stirring for 14-20 h, and cooling to a room temperature to obtain a reaction product; adjusting the pH value to be neutral, then separating an organic phase, extracting a water phase by using an organic solvent, combining the organic phases, drying, filtering, and carrying out reduced pressure distillation to obtain N-cyclohexylmethyl carbamate; and step 2, carrying out thermal cracking reaction on the N-cyclohexylmethyl carbamate and a catalyst B, collecting, rectifying and purifying to obtain the cyclohexyl isocyanate. According to the method disclosed by the invention, the cyclohexyl isocyanate is synthesized by adopting a carbamate method, so that environmental hazards caused by phosgene are effectively avoided, and the cyclohexyl isocyanate with high yield and high purity is obtained.

The invention discloses a methyl carbamate phosgene-containing tail gas treatment device, and relates to the technical field of tail gas treatment, the methyl carbamate phosgene-containing tail gas treatment device comprises an alkaline washing tower, and the lower side of the front end of the alkaline washing tower is provided with a water tank; the water tank is sequentially provided with a filter tank body I, a mixing tank body and a filter tank body II from left to right, the bottoms of the filter tank body I and the filter tank body II are communicated with the mixing tank body through ports, one side, facing the mixing tank body, of each port is provided with a mixing assembly, and one side, far away from the mixing tank body, of each port is provided with a filter plate; a switching module is mounted on the mixing tank body, the switching module comprises a driving part and two groups of composite working parts, and the driving part is used for driving the two groups of composite working parts to act in a staggered manner; and a cleaning module is mounted on the composite work piece. According to the methyl carbamate phosgene-containing tail gas treatment device, non-stop efficient treatment, precise cleaning and medicament regeneration are realized through double-channel alternate filtration, automatic backwashing and waste liquid kinetic energy driven mixing, and the safety, continuity and resource utilization rate are remarkably improved.

The invention provides an antibacterial, antiviral, mildew-proof, formaldehyde-removing and TVOC-removing additive, impregnated bond paper, a veneer artificial board and a preparation method of the antibacterial, antiviral, mildew-proof, formaldehyde-removing and TVOC-removing additive. The antibacterial, antiviral, mildew-proof, formaldehyde-removing and TVOC-removing additive comprises a zinc ion amino long-carbon-chain antimicrobial agent, a zinc-series catalytic decomposition agent and a solvent; the zinc ion amino long-carbon-chain antimicrobial agent is prepared by the following steps: reacting zinc salt with a long-carbon-chain organic matter antimicrobial agent in an aqueous solution to obtain a zinc ion-loaded long-carbon-chain antimicrobial agent, then adding methyl carbamate, and carrying out nucleophilic substitution reaction or ammonolysis reaction. Compared with other single-function or double-function additives, the multifunctional additive is a product integrating five functions, can achieve the functions of five pain points of indoor decoration in one step, is convenient to add and use, and solves the problems of interference on compatibility and complex operation when multiple single-function agents are added and used at the same time.

The utility model mainly relates to the field of filtering equipment, and provides material filtering equipment for processing methyl carbamate, which structurally comprises a kettle body, an annular seat is fixedly connected to the top of the inner wall of the kettle body through bolts, and a conical filtering sleeve is fixedly arranged at the bottom of the annular seat. An auxiliary conical sleeve is fixedly connected to the middle of the top end of the conical filter sleeve through a bolt, and a connecting pipe is inserted into the top of the auxiliary conical sleeve; a material pumping pipe is fixedly arranged at the input end of the material pumping pump, an extension pipe is fixedly arranged at one end of the material pumping pipe, a solid-liquid mixture enters the auxiliary conical sleeve, and a solid catalyst at the bottom of the auxiliary conical sleeve is squeezed into a filtering area between the conical filtering sleeve and the auxiliary conical sleeve to be continuously filtered due to the accumulation weight of materials in the auxiliary conical sleeve; at the moment, the solid catalyst pushed to be close to the upper part of the conical filtering sleeve is basically filtered, and is pumped out through equipment such as a material pump, so that dynamic continuous filtering operation of the solid catalyst by the equipment is realized.

The application discloses a zinc-aluminum composite oxide catalyst and a preparation method and application thereof, and belongs to the technical field of catalytic materials and non-phosgene isocyanate preparation. The application solves the problems of high reaction temperature, low raw material concentration, many side reactions and insufficient catalyst stability in the process of preparing isocyanate by pyrolysis of carbamic acid ester. The zinc-aluminum composite oxide catalyst comprises a composite oxide of zinc and aluminum, and has a dual-phase heterogeneous structure of ZnO and ZnAl2O4 spinel. When the catalyst is applied to the preparation of 4-(4'-phenylaminomethylcarbamate) diphenyl methane isocyanate (MMI) and diphenyl methane diisocyanate (MDI) by vacuum thermal decomposition of diphenyl methane diamino methylcarbamate (MDC), the self-polymerization and condensation side reactions in the reaction process can be effectively inhibited by the synergistic effect of the ZnO phase and the spinel phase, the selectivity and yield of the target product are improved, and the catalyst has good mechanical stability and is easy to recycle and cyclically used.

The invention provides a method for detecting dimethyl carbamyl chloride in palmitoyl chloride and application, and belongs to the technical field of pharmaceutical chemistry detection. The method comprises the following steps: mixing dimethyl carbamate (DMCC-DER) with a diluent to prepare a standard solution; mixing palmitoyl chloride with a diluent, heating, and cooling to obtain a sample solution; detecting the purity of the standard substance solution and the sample solution obtained in the step (1) and the step (2); and the diluent is methanol. The method is simple to operate, reagents are easy to obtain, the sensitivity can reach 3.0 mu g / ml, the accuracy is high, the reproducibility is good, and reference and technical support are provided for quality control of DMCC and safety and quality controllability of subsequent pharmaceutical products.

The present invention relates to fungicidal compositions comprising at least one compound selected from the group consisting (I-1) methyl N-[[5-[1-(2,6-difluoro-4-isopropyl-phenyl)pyrazol- 3-yl]-2-methyl-phenyl]methyl]carbamate, (I-2) methyl N-[[5-[1-(4-cyclopropyl-2,6-difluoro- phenyl)pyrazol-3-yl]-2-methyl-phenyl]methyl]carbamate, (I-3) methyl N-[[5-[1-(4-chloro-2,6- difluoro-phenyl)pyrazol-3-yl]-2-methyl-phenyl]methyl]carbamate, (I-4) methyl N-[[5-[1-[2,6- difluoro-4-(trifluoromethyl)phenyl]pyrazol-3-yl]-2-methyl-phenyl]methyl]carbamate, and as active component 2) at least one compound, or an N-oxide, or an agriculturally useful salt thereof, selected from the group consisting of (II-1) 2-fluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3- yl]benzanilide, (II-2) N-methoxy-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3- yl]phenyl]methyl]cyclopropanecarboxamide, (II-3) N,2-dimethoxy-N-[[4-[5-(trifluoromethyl)-1,2,4- oxadiazol-3-yl]phenyl]methyl]propenamide wherein the weight ratio of compound I to compound II is from 10:1 to 1:10. The invention also relates to an agrochemical composition comprising the composition and a solvent of solid carrier. Further, the invention relates to a non-therapeutic use of the inventive compositions controlling phytopathogenic harmful fungi.

The invention provides a synthesis method for preparing urea from carbamate derivatives, a urea compound and application. The synthesis method is a novel method for preparing the urea compound through the reaction of carbamate and amine, the exchange reaction of aryl substituted methyl carbamate and amine is realized innovatively through the concerted catalysis strategy of light and copper, and the urea compound is efficiently generated. The reaction conditions are mild, the target product yield is high, and the universality is good. The method is expected to be expanded to a degradation reaction system of polyurethane compounds, and provides important technical support for solving the traditional polyurethane degradation problem and reducing the environmental pollution risk caused by the polyurethane degradation problem.

The present invention relates to fungicidal compositions comprising at least one compound selected from the group consisting (I-1) methyl N-[[5-[1-(2,6-difluoro-4-isopropyl-phenyl)pyrazol- 3-yl]-2-methyl-phenyl]methyl]carbamate, (I-2) methyl N-[[5-[1-(4-cyclopropyl-2,6-difluoro- phenyl)pyrazol-3-yl]-2-methyl-phenyl]methyl]carbamate, (I-3) methyl N-[[5-[1-(4-chloro-2,6- difluoro-phenyl)pyrazol-3-yl]-2-methyl-phenyl]methyl]carbamate, (I-4) methyl N-[[5-[1-[2,6- difluoro-4-(trifluoromethyl)phenyl]pyrazol-3-yl]-2-methyl-phenyl]methyl]carbamate, and as active component 2) at least one compound, or an N-oxide, or an agriculturally useful salt thereof, selected from the group consisting of (II-1) flumetylsulfurim, (II-2) feneptamidoquin, (II-3) 3-[3-(3- chloro-2-fluoro-phenoxy)-6-methyl-pyridazin-4-yl]-5-[(2-chloro-4-methyl-phenyl)methyl]-5,6- dihydro-4H-1,2,4-oxadiazine, wherein the weight ratio of compound I to compound II is from 10:1 to 1:10. The invention also relates to an agrochemical composition comprising the composition and a solvent of solid carrier. Further, the invention relates to a non-therapeutic use of the inventive compositions controlling phytopathogenic harmful fungi.

This invention discloses a method for synthesizing methyl 1,6-hexamethylenedicarbamate using a bismuth-based metal salt as a catalyst. The method includes the following steps: adding 1,6-hexanediamine, dimethyl carbonate, and a catalyst to a reactor, and stirring the reaction at 60–100°C and atmospheric pressure for 6–9 hours to obtain methyl 1,6-hexamethylenedicarbamate; the catalyst is a bismuth acetate metal salt or a supported bismuth acetate. The catalyst preparation process of this invention is simple, can be recycled multiple times, reduces cost and loss, and improves product yield.

The present application relates to a kind of fast curing two-component condensation dealcoholization type silicone glue and preparation method, raw material includes A component: hydroxyl silicone oil or alkoxy silicone oil, filler A, crosslinking agent, coupling agent, catalyst;B component: inert silicone oil, Burgess reagent (N- (triethylammonium sulfuryl) methyl carbamate), filler B.The adhesive curing process organosilicon condensation dealcoholization vulcanization and the effect of synergistic catalysis can be achieved by the reaction of alcohol dehydration into alkene with Burgess reagent as dehydrating agent for alcohol dehydration, ultimately realizes the room temperature fast deep layer curing of dealcoholization type organosilicon adhesive, can realize 4h glue layer curing depth ≥20mm;The adhesive is suitable for the application scene requiring room temperature fast curing or deep layer potting etc., can significantly improve production efficiency.

The invention discloses a plastic packaging material for food and a preparation method of the plastic packaging material. On one hand, the invention provides the plastic packaging material for the food, and the plastic packaging material is prepared from the following raw material components in parts by mass: 60 parts of HDPE (High-Density Polyethylene) resin, 40 to 50 parts of EVOH (Ethylene Vinyl Alcohol) resin, 24 to 32 parts of non-isocyanate polyurethane prepolymer and 6 to 10 parts of cinnamyl aldehyde grafted nano titanium dioxide; the non-isocyanate polyurethane prepolymer is prepared from the following raw material components in parts by mass: 60 to 68 parts of methyl 1, 6-hexamethylene dicarbamate, 6 to 8 parts of bio-based polyol, 10 to 16 parts of eugenol, 1 to 3 parts of ferric oxide and 2 to 4 parts of zinc acetate. On the other hand, the invention provides a preparation method of the plastic packaging material for food. The packaging material disclosed by the invention is excellent in high and low temperature resistance, excellent in solvent resistance and moisture resistance, excellent in oxygen barrier property, free of harmful substance precipitation and relatively excellent in antibacterial property.