17 results about "Vapor phase chromatography" patented technology

This invention relates to a bag-film laminate comprising a base layer, a gas barrier layer, and a sealant layer sequentially laminated together, wherein the amount of lubricant present on the surface of the sealant layer is 5 mg / m³. 2 Up to 25 mg / m 2 The surface roughness (Ra) of the sealant layer is 0.1 μm to 0.5 μm. The amount of lubricant is obtained by cutting the bag-film assembly into 100 mm × 100 mm sections in the MD direction and TD direction, dropping 5 ml of chloroform onto the surface of the sealant layer of the bag-film assembly and letting it stand for 1 minute to prepare a lubricant extraction solution, and then using gas chromatography to measure the amount of lubricant contained in the lubricant extraction solution.

The present application relates to a surfactant composition containing an alkyl hydroxy ether acetate (A) represented by the following general formula (1) and a compound (I) detected between retention time 10 minutes and 17 minutes in a gas chromatography using petroleum ether in conformity with JIS K8593, the ratio of the peak area of the compound (I) to the peak area of the petroleum ether determined by the gas chromatography being 0.02% to 50%.R 1 -CH(OH)-CH2-OCH2COOM 1 (1) [In the general formula (1), R 1 represents an alkyl group having 8 to 12 carbon atoms, M 1 represents a hydrogen atom, a sodium atom, a potassium atom or triethanolammonium.]

This isocyanate composition contains: bis(isocyanatomethyl)bicyclo[2.2.1]heptane; and a specific compound having a molecular weight of 189, which is detected separately from bis(isocyanatomethyl)bicyclo[2.2.1]heptane by gas chromatography.

This application relates to the field of power equipment testing technology, and in particular to a method and apparatus for detecting the amount of dissolved gas degassing in oil. The method includes: acquiring oil sample information and operating condition information of the corresponding expandable gas collector; determining the pressure change data of the expandable gas collector based on the oil sample information and operating condition information; and calculating the total amount of dissolved gas degassing in the oil sample based on the pressure change data and a preset mapping relationship. This solves the problems of gas chromatography, which is cumbersome to operate, requires highly skilled personnel, has high instrument and consumable costs, and is time-consuming, making real-time monitoring impossible; and vacuum degassing, which requires strict vacuum levels, has high equipment purchase and maintenance costs, poor degassing effect stability, difficulty in guaranteeing detection accuracy, and is prone to oil sample contamination and complex operation.

The application provides a method for preparing adamantane, which comprises: isomerizing tetrahydrodicyclopentadiene in the presence of a mesoporous mordenite molecular sieve catalyst with acid sites established by an organic acid, in the presence of an optional organic solvent, and in a hydrogen-containing atmosphere; and calculating the NH3-TPD peak area of the catalyst by integration, wherein the peak area of the weak acid center of the catalyst is greater than or equal to 330, the peak area of the strong acid center of the catalyst is less than or equal to 282, and the specific surface area of the catalyst is greater than or equal to 300 m 2 / g. In the synthesis of adamantane by the method, the isomerization reaction of adamantane is carried out in the presence of the above catalyst, at a reaction temperature of 250 DEG C, a hydrogen pressure of 1 Mpa, and in a 100-ml stainless steel autoclave. The product composition is analyzed by gas chromatography, and the chromatographic column is an HP-5 capillary column with a column length of 30 m. The purity of adamantane can reach more than 99%.

This invention relates to the field of detection and analysis technology, and discloses a pre-column derivatization-liquid chromatography-tandem mass spectrometry (LC-MS / MS) method for the detection of perfluorocarboxylic acids and their substitutes. The highly sensitive and selective method provided by this invention, based on 3-nitrophenylhydrazine pre-column derivatization-LC-MS / MS, achieves good correlation (R0) of nine target analytes (C2-C9 perfluorocarboxylic acids and GenX) within a wide linear range of 0.0001-100 ng / mL. 2 The method has a detection limit as low as 0.83 ng / L and a quantitation limit of 2.76 ng / L, with a sensitivity of 0.83 ng / L for short-chain trifluoroacetic acid, significantly better than traditional gas chromatography. The spiked recoveries in ultrapure water matrix range from 88.2% to 115.7%, with inter-day and intra-day precisions of 0.2% to 17.61% and 3.5% to 16.3%, respectively, demonstrating good accuracy and reproducibility. This method incorporates highly polar short-chain perfluorocarboxylic acids, previously only analyzable by GC-MS, into the LC-MS / MS detection system. It also achieves trace detection of the novel pollutant GenX at the ng / L level, with significantly higher sensitivity than existing methods.

The present application belongs to the technical field of biochemical detection, and discloses a rapid detection method for sodium diacetate in duck blood, which solves the technical problem that the existing detection method cannot accurately detect low content of sodium diacetate in duck blood. The steps are as follows: (1) adding phosphoric acid to sodium diacetate standard solutions with different concentrations to obtain a to-be-detected standard solution; detecting the peak area of the to-be-detected standard solution by gas chromatography, and preparing a standard curve of the concentration of the sodium diacetate standard solution and the peak area; (2) pretreating duck blood samples to obtain a to-be-detected solution; (3) detecting the to-be-detected solution by gas chromatography, and bringing the obtained peak area into the standard curve of step (1) to obtain the concentration of sodium diacetate in the to-be-detected solution. The rapid detection method has a detection limit of 0.007 g / kg, a sample standard addition recovery rate of 92.5-102.4%, good repeatability, a coefficient of variation of less than 10%, and high detection accuracy.

The application provides a squalene fermentation liquor and a method for determining the content of extracted process sample acetone, n-heptane, ethanol and squalene, relates to the field of chemical industry, and specifically comprises the following steps: S1, preparing a test solution: determination of acetone, n-heptane and ethanol: accurately weighing n-propanol and a sample, and shaking to obtain; determination of squalene: accurately weighing squalene and n-propanol in a volumetric flask, adding ethyl acetate to the scale, and shaking to obtain; the test solution is detected by using a gas chromatography method, and the content of acetone, n-heptane, ethanol and squalene is calculated by using an internal standard method; the linear relationship between the theoretical concentration and the detected concentration in the concentration range is investigated, ethanol r=0.999, the average recovery rate is 101%; acetone r=1.000, the average recovery rate is 99%; n-heptane r=1.000, the average recovery rate is 100%; and squalene r=1.000, the average recovery rate is 100%.

This isocyanate composition contains: bis(isocyanatomethyl)bicyclo[2.2.1]heptane; a first specific compound having a molecular weight of 199, which is detected separately from bis(isocyanatomethyl)bicyclo[2.2.1]heptane by gas chromatography; and a second specific compound having a molecular weight of 176, which is detected separately from bis(isocyanatomethyl)bicyclo[2.2.1]heptane and the first specific compound by gas chromatography.

The application discloses a detection method of related substances in (3S, 5S)-3-Boc-amino-5-methylpiperidine. The related substances are detected by using a gas chromatography method. The detection method provided by the application solves the interference problem of other impurities possibly introduced in the process. The application researches and screens gas phase lining pipes of different materials, capillary columns of different stationary liquids, different sample injection procedures, sample injection bottle materials and sample dispensing droppers, provides an optimized detection method, and proposes solutions to the problems of poor reproducibility, adsorption and leaching in the detection process, so that the accuracy of the detection result is ensured.

Invention Title: A Method for Detecting Ethylene Glycol and Diethylene Glycol in Aripiprazole Oral Solution Abstract: This invention provides a method for detecting ethylene glycol and diethylene glycol in aripiprazole oral solution, applicable to the field of drug oral preparation detection technology, especially in the field of pharmaceutical quality control, requiring gas chromatography detection methods to monitor pharmaceutical excipients and byproducts. This analytical method overcomes the limitations of ethylene glycol and diethylene glycol, which lack ultraviolet absorption methods. The sample solution is injected into the injection port via a microsyringe, and instantly vaporized in a high-temperature vaporization chamber, increasing sensitivity and accuracy, and solving the problems of low detection efficiency and low precision. Separation and detection efficiency are improved by optimizing column temperature and other conditions. This invention uses high-performance gas chromatography (HPLC) with a 100% bonded cross-linked polyethylene glycol (PEG) capillary column, a flame ionization detector, nitrogen as the carrier gas, and an organic solvent as the diluent. It uses a conventional chromatographic column, an automated injection method, and reduces costs. Gradient temperature elution is employed for separation and detection. This invention relates to a method for the detection of ethylene glycol and diethylene glycol in aripiprazole oral solution. This method has good separation, high specificity, high precision, and good repeatability, and meets the requirements for methodological research on the determination of ethylene glycol and diethylene glycol in aripiprazole oral solution.

The present invention is a method for measuring three types of greenhouse gases including CO2, CH4, and N2O contained in an atmosphere by using GC, including: a separation step of introducing the atmosphere which may contain the greenhouse gases as components into a column 15 of the GC and separating various components in the atmosphere including the greenhouse gases in a time direction; a first detection step of detecting each of CO2 and N2O in a gas after having been subjected to a component separation in the separation step using a BID 16; a second detection step of detecting CH4 in the gas after having been subjected to the component separation in the separation step using a FID 17; and a quantitative determination step of preparing chromatograms respectively based on detection signals obtained in the first and second detection steps, and quantifying CO2, CH4, and N2O respectively from peaks.

The application discloses an on-line monitoring device and method for dissolved gas in transformer oil based on infrared spectrum, which comprises a transformer oil gas separation part, an infrared spectrum gas detection part and a data processing part. The method comprises the following steps: firstly, carrying out oil gas separation; then, sending the obtained dissolved gas in oil into a gas chamber and scanning the gas chamber by using an infrared spectrometer to obtain a spectrum diagram; and finally, obtaining the content of various target gases in oil by using a gas quantitative analysis model. The application uses infrared spectrum method as the gas detection part, has the advantages of fast spectrum data acquisition, no consumption of gas samples, wide detection range, high stability, maintenance-free, long-term operation monitoring cost, etc. compared with the most widely used gas chromatography method for on-line monitoring of gases in transformer oil. The device adopts a structure based on single-chamber vacuum degassing, solves the problem of spectrum baseline offset distortion, and does not need to consume nitrogen as background, thereby improving the automation degree of the device.

The application discloses a detection method of di(2-chloroethyl)amine hydrochloride, and belongs to the technical field of detection methods. The detection method of di(2-chloroethyl)amine hydrochloride comprises the following steps: (1) using alkali to free di(2-chloroethyl)amine hydrochloride into di(2-chloroethyl)amine in deionized water, and using an organic solvent to extract to obtain a test sample; (2) detecting the purity of the test sample by gas chromatography, and the chromatographic conditions are as follows: the temperature of a sample inlet is 200-250 DEG C, the initial temperature of a chromatographic column is 40-50 DEG C, and is maintained for 1-3 min; then the temperature is increased to 200-250 DEG C at a rate of 30-40 DEG C / min, and is maintained for 3-5 min; and the temperature of a detector is 240-300 DEG C. The detection method is simple to operate, and can meet the needs of detection of di(2-chloroethyl)amine hydrochloride.

The utility model belongs to soil detection technical field especially for soil cyanide determination device based on gas chromatography, including including preprocessing unit, gas chromatography detection unit and automation control unit, preprocessing unit includes ultrasonic extraction module, automatic distillation module and derivatization module, gas chromatography detection unit includes headspace sampler, chromatographic column and detector, automation control unit includes microprocessor and data processing module, still include the derivatization device for derivatization module in preprocessing unit, the utility model, adopt ultrasonic extraction and automatic distillation combination, shorten the pretreatment time, shake the reactor ware in the derivatization process simultaneously, make the reactant fast mixing reaction, promote the reaction speed and efficiency, and the detection sensitivity is promoted to chloramine T derivatization technology, and the sample processing is from data output and all is by microprocessor control, reduces the human error, promotes the accuracy of detection, and the speed is fast, the efficiency is high, and the convenient use.

This invention provides a method for detecting the diethyl sulfate content in methyl 4-acetamido-2-ethoxybenzoate. The method involves derivatizing the sample with sodium iodide-ascorbic acid and detecting the sample using a headspace gas chromatograph equipped with an ECD detector. The chromatographic column is an Agilent DB-624 30m × 0.53mm × 3μm column, the injection port temperature is 220℃, the detector temperature is 250℃, and the carrier gas is N2. 2， Flow rate: 1.5 mL / min, temperature programmed: initial column temperature 70℃, increased to 150℃ at a rate of 5℃ / min and held for 0 min; then run at 240℃ and held for 5 min, flow rate 3 mL / min. This invention provides a convenient, efficient, and accurate method for detecting the diethyl sulfate content in methyl 4-acetamido-2-ethoxybenzoate. This method uses gas chromatography to detect the diethyl sulfate content in methyl 4-acetamido-2-ethoxybenzoate, thereby effectively ensuring medication safety.

The present application relates to a kind of test methods of benzene in bulk drug, using gas chromatography to detect, bulk drug is dissolved to diluent, obtain the liquid to be measured;The liquid to be measured is using headspace sampling, carries out gas chromatography detection, obtains gas chromatogram;According to the peak area of benzene in the gas chromatogram, the content of benzene in bulk drug is calculated.The detection method established in the present application is high in sensitivity, easy and fast to operate, accurate and reliable, good in repeatability, and the method validation proves the specificity, accuracy, repeatability, detection limit, limit of quantification, linearity and range of the method;In addition, the present application limits headspace sampling, avoids the problem that due to the concentration of test sample being too high, pollution liner tube and sample inlet;Provide technical support for the analysis and detection of benzene in bulk drug.