23 results about "Polar lipids" patented technology

The invention relates to the technical field of functional lipid preparation, in particular to high-purity nannochloropsis oculata polar lipid enriched by an enzymic method and a preparation method of the high-purity nannochloropsis oculata polar lipid. The method comprises the following steps: specifically and selectively hydrolyzing triglyceride by using immobilized Lip2 lipase to generate glycerol and free fatty acid, retaining and enriching polar lipid components, and carrying out centrifugal filtration and molecular distillation to obtain the high-purity nannochloropsis oculata polar lipid. The invention provides a method for preparing high-purity polar lipid by performing enzymolysis on nannochloropsis oculata oil by using lipase Lip2 produced by yarrowia lipolytica, which maximally retains the polar lipid and obtains a high-purity polar lipid product through the specific catalytic action of Lip2 lipase. The method which is mild in reaction condition, environment-friendly, simple in step and high in purity is provided for efficient enrichment of the nannochloropsis oculata polar lipid, the prepared polar lipid product is extremely high in purity, and the blank of efficient preparation of the nannochloropsis oculata polar lipid in the prior art is filled.

Disclosed herein are compositions for use in a variety of agricultural methods, the compositions comprising a plurality of naturally derived lipid particles comprising a phospholipid, a non-polar lipid, and a surface modifier, and further comprising a biologically active substance.

Provided is a preparation method for an adiposome, comprising the following steps: S1) subjecting polar lipids and neutral lipids to intermittent ultrasonic emulsification in a buffer solution to obtain a crude emulsion; and S2) purifying the crude emulsion to obtain the adiposome. Compared with the prior art, the present invention uses an ultrasonic emulsification method to prepare the adiposome, so that the quality of the adiposome prepared in different batches is controllable, and the preparation of the adiposome can be efficiently completed. Moreover, high-energy mechanical vibration and ultrasonic cavitation effects of ultrasonic waves are utilized in the ultrasonic emulsification method to widen the selection of raw materials for adiposomes, so that the method can be used to not only prepare an adiposome with unsaturated fatty acid chain phospholipids and neutral lipids as raw materials, but also synthesize an adiposome with saturated fatty acid chain phospholipids, neutral lipids, or high-melting-point lipids as raw materials. In addition, the utilization of raw materials can be improved, and the scale of adiposome production can be expanded.

The invention discloses a preparation method of bovine spinal cord peptide, belongs to the technical field of biology, and is used for solving the technical problems that in the prior art, degreasing agents such as petroleum ether are weak in polar lipid dissolving capacity, and enzymatic hydrolysate is separated by adopting a conventional nanofiltration membrane, so that the manufacturing cost is high, and the service life is short. The preparation method of the bovine spinal cord peptide comprises the following steps: S1, cleaning fresh bovine spinal cords, crushing the cleaned bovine spinal cords into blocks, and pulping the blocks to obtain homogenate tissues; adding a degreasing agent into the homogenized tissue, and performing ultrasonic treatment to obtain degreased spinal cord; s2, adding compound enzyme into the degreased spinal cord for reaction to obtain enzymatic hydrolysate; carrying out enzyme deactivation on the enzymatic hydrolysate in boiling water to prepare a bovine spinal cord crude peptide solution; s3, centrifuging the bovine spinal cord crude peptide solution, and collecting supernate; and passing the supernate through a modified ultrafiltration membrane, and circularly performing ultrafiltration for multiple times to prepare the bovine spinal cord peptide. According to the method, the homogenate tissue is deeply degreased by designing the composite degreasing agent with a surfactant-like structure; and the modified ultrafiltration membrane is used for improving the purity of the filtered bovine spinal cord peptide.

The present invention relates to a method for preparing an algae extract from an algae biomass comprising chlorophyll, polar lipids and possibly present triglycerides, said algae extract comprising polar lipids dissolved in 1, 3-propanediol and whose parameter a according to the CIELAB color space is greater than or equal to-5, preferably greater than-10, preferably greater than-10, preferably greater than-10, preferably greater than-10, preferably greater than-10, preferably greater than-10, preferably greater than-10, preferably greater than-10, preferably greater than-10, preferably greater than-10, preferably greater than-10, preferably to the use of said algae extract as a cosmetic active agent, and to a cosmetic composition comprising said algae extract.

The invention provides lipid rich in sphingomyelin, a preparation method and a phospholipid ingredient for infant formula milk powder, and relates to the technical field of dairy product processing.The lipid rich in sphingomyelin and the preparation method thereof have the advantages that primary separation is carried out by the aid of supercritical carbon dioxide extraction technologies, secondary extraction is carried out by the aid of follow-up ethyl alcohol serving as entrainer, non-polar lipid can be effectively removed, and the lipid rich in sphingomyelin can be obtained; and phospholipids with high polarity, especially sphingomyelin, are retained. The ethanol concentration is controlled to be 20% (v / v), so that the solubility and the selective extraction efficiency of lipid rich in sphingomyelin are improved, and a higher sphingomyelin enrichment degree is realized in a final product. Meanwhile, ethanol extraction can be directly combined with a freezing crystallization method, other organic solvents are not introduced into the method, the method is green and safe, complex equipment support is not needed, the technological process is short, operation is easy and convenient, cost is low, and the method is suitable for rapid preparation.

The invention discloses a structure annotation method for analyzing positions sn-and C = C of lipid based on liquid chromatography-organic matter ion electron collision excitation mass spectrometry. According to the method, a proper amount of 0.1 mM sodium acetate is added during lipid redissolution, so that polar lipid and neutral lipid are analyzed at the same time through one-time sample introduction. Meanwhile, a method for automatically annotating the complex organic matter ion electron collision excitation mass spectrum is developed, and the method comprises the steps of (1) extracting mass spectrum information in original data, (2) identifying lipid subclasses, (3) matching lipid total composition, (4) pairing sn-position, (5) positioning C = C position, and (6) determining annotation level. For 34 lipid standard substances in serum, the annotation accuracy rates of the annotation method on sn-and C = C isomer levels are 100% and 82.3% respectively. A total of 1312 sn-isomers and 1033 C = C isomers are annotated from mixed plasma samples of healthy people and patients with mild cognitive impairment of Alzheimer's disease. In a word, the lipid fine structure analysis method developed by the invention has the characteristics of simple pretreatment, high coverage and efficient annotation of the lipid fine structure.

Disclosed herein are compositions including a plurality of nature-derived lipid particles (NLPs) comprising phospholipids, essential oils, blends of essential oils and polar lipids, and optionally surface modifiers, and further comprising bioactives, wherein the NLPs comprise a hydrophobic core, for use in a variety of agricultural methods.

A method for producing highly bioavailable oil compositions from biomasses and, in particular, autotrophic algal biomasses, and providing characterized and clarified mass balance breakdowns and component products therefrom without loss of significant mass in an extraction such as a liquid-liquid extraction, polarity segregation and use of mechanical cartridges.

The present invention relates to enzymatic methods for producing a stable lipid-based liquid crystalline phase of Fd3m or Hll space group, compositions comprising such phases, and uses thereof, wherein the starting mixture comprises 30-65 wt% polar lipids and 35-70 wt % oil which are well dispersed and triacylglycerol lipase is added to produce oil hydrolysate which in presence of aqueous solvent results in liquid crystal formation.

The present invention relates to methods of producing industrial products from plant lipids, particularly from vegetative parts of plants. In particular, the present invention provides oil products such as biodiesel and synthetic diesel and processes for producing these, as well as plants having an increased level of one or more non-polar lipids such as triacylglycerols and an increased total non-polar lipid content. In one particular embodiment, the present invention relates to combinations of modifications in two or more of lipid handling enzymes, oil body proteins, decreased lipid catabolic enzymes and / or transcription factors regulating lipid biosynthesis to increase the level of one or more non-polar lipids and / or the total non-polar lipid content and / or mono-unsaturated fatty acid content in plants or any part thereof. In an embodiment, the present invention relates to a process for extracting lipids. In another embodiment, the lipid is converted to one or more hydrocarbon products in harvested plant vegetative parts to produce alkyl esters of the fatty acids which are suitable for use as a renewable biodiesel fuel.

The present invention relates to methods of producing industrial products from plant lipids, particularly from vegetative parts of plants. In particular, the present invention provides oil products such as biodiesel and synthetic diesel and processes for producing these, as well as plants having an increased level of one or more non-polar lipids such as triacylglycerols and an increased total non-polar lipid content. In one particular embodiment, the present invention relates to combinations of modifications in two or more of lipid handling enzymes, oil body proteins, decreased lipid catabolic enzymes and / or transcription factors regulating lipid biosynthesis to increase the level of one or more non-polar lipids and / or the total non-polar lipid content and / or mono-unsaturated fatty acid content in plants or any part thereof. In an embodiment, the present invention relates to a process for extracting lipids. In another embodiment, the lipid is converted to one or more hydrocarbon products in harvested plant vegetative parts to produce alkyl esters of the fatty acids which are suitable for use as a renewable biodiesel fuel.

The present disclosure provides a method for delivering a nucleic acid cargo to the liver of a subject, the method comprising administering to the subject a lipid nanoparticle encapsulating the nucleic acid and comprising a non-polar lipid. The lipid nanoparticle may exhibit a blebbed morphology, despite the absence or low levels of phospholipid. The disclosure further provides compositions for delivering nucleic acid cargo to the liver in order to treat various diseases, disorders and conditions in the subject.

The present disclosure provides a lipid nanoparticle comprising: nucleic acid cargo; ionizable lipid; non-polar, neutral lipid, such as a phospholipid; non-polar lipid, such as a glyceride; and sterol, the lipid nanoparticle being unshielded and wherein each mol% content is relative to total lipid present in the lipid nanoparticle.

The present invention relates to a two-step emulsification process for preparing a lipid and protein component-containing composition comprising large lipid globules, preferably coated with polar lipids, and to the compositions thus obtained. Optionally, the composition comprising the lipid and protein components is spray-dried. The resulting compositions are useful for feeding infants.

This application relates to compositions comprising polar lipids for maintaining or increasing mobility and vitality. In particular, the invention relates to the use of milk fat globule membrane materials comprising one or more polar lipids in the manufacture of compositions or pharmaceuticals intended for (a) maintaining or increasing lean muscle mass and / or maintaining or decreasing fat mass in human subjects; (b) increasing daily activity and reducing sedentary time in human subjects; and / or (c) after daily administration of the composition or pharmaceuticals for a period of at least three or four months, and wherein the human subjects exercise at least two days per week, compared to the sedentary time and / or low-intensity physical activity time prior to the commencement of daily administration of the composition or pharmaceuticals, a reduction of at least 7 minutes per day in sedentary time and / or an increase of at least 3 minutes per day in low-intensity physical activity time in human subjects.

Disclosed herein are compositions including a plurality of nature-derived lipid particles (NLPs) comprising phospholipids, essential oils, blends of essential oils and polar lipids, and optionally surface modifiers, and further comprising bioactives, wherein the NLPs comprise a hydrophobic core, for use in a variety of agricultural methods.

Methods of treating or preventing gestational diabetes mellitus (GDM) and / or treating or preventing one or more GDM-associated risks or one or more sequelae of GDM by administering one or more polar lipids, in addition to uses, compositions, and medicaments comprising one or more polar lipids to treat or prevent gestational diabetes mellitus and / or treat or prevent one or more GDM-associated risks or one or more sequelae of GDM.

To provide long-acting, non-aqueous pharmaceutically acceptable compositions of active ingredients for subcutaneous injection.SOLUTION: Provided is an injectable pharmaceutically acceptable composition, comprising: a) a pharmaceutically active agent; b) a polar lipid at about 5.0 to 40.0% w / w; and c) a triglyceride carrier at about 5.0 to 70.0% w / w.SELECTED DRAWING: Figure 1

To provide a prepared food product, in particular a prepared structured emulsion and a method for preparing the same.SOLUTION: A polar lipid composition for a prepared food product is provided. The polar lipid composition contains 60% or more, preferably 90% or more of phospholipids with respect to the total mass of the polar lipid composition. With respect to the total mass of the phospholipids, it contains 25-35% of phosphatidylcholine (PC), 20-35% of phosphatidylethanolamine (PE), 10-30% of phosphatidylethanolamine (PE), and 10-25% of sphingomyelin (SM). Preferably, it is provided from one or more types selected from plant-derived phospholipid products and animal-derived phospholipid products. More preferably, the plant-derived phospholipid product is sunflower phospholipid and / or soybean phospholipid, and the animal phospholipid product is cheese powder, MFGM, milk concentrate phospholipid powder, and / or milk sphingomyelin, preferably milk cheese powder.SELECTED DRAWING: None

The present application relates to the technical field of functional lipid preparation, and particularly relates to a method for enriching high-purity Nannochloropsis polar lipid by enzyme method and a preparation method thereof. The immobilized Lip2 lipase is used to specifically and selectively hydrolyze triglyceride to generate glycerol and free fatty acid, and the polar lipid component is reserved and enriched, and then high-purity Nannochloropsis polar lipid is obtained through centrifugal filtration and molecular distillation. The present application provides a method for preparing high-purity polar lipid by enzymolysis of Nannochloropsis oil using the lipase Lip2 produced by Yarrowia lipolytica. The specific catalytic effect of the Lip2 lipase maximally reserves the polar lipid, and high-purity polar lipid product is obtained. The present application provides a method for high-efficiency enrichment of Nannochloropsis polar lipid, which is mild in reaction condition, friendly to environment, simple in steps and high in purity. The prepared polar lipid product is extremely high in purity, and fills the blank of high-efficiency preparation of Nannochloropsis oil polar lipid in the prior art.

The present invention relates to a method for providing a lipid fermentation product having high polarity using skin flora. The lipid fermentation product of the present invention contains glycolipids with high polarity, and thus can easily form emulsified self-assembled particles and liquid crystal emulsions to improve emulsification properties.

Disclosed herein are compositions comprising a plurality of naturally-derived lipid particles comprising a phospholipid, a non-polar lipid, and a surface modifier, and further comprising a bioactive material, for use in various agricultural methods.