The invention provides a saline taste meal replacement nutrition bar applied to edible of a diabetic and a preparation method of the saline taste meal replacement nutrition bar, and belongs to the field of food. The saline taste meal replacement nutrition bar is prepared from the following components: soy protein, corn crisp chips, puffing quinoa ball, oatmeal, chia seed, soybean isolate protein powder, concentrated milk protein powder, oat fiber powder, polydextrose, inulin, resistance dextrin, maltitol, glycerinum, phospholipid, sunflower seed oil, powdered soy, hydrolyzed vegetable protein,edible salt, essence for food, composite mineral substance, decavitamin, a potato extractive, L-carnitine, chestnut powder and saline taste flavor components, through mixing, extrusion forming, cutting, segment type microwave baking and cooling, a saline taste meal replacement product is further obtained, the preparation method is simple and efficient, the saline taste meal replacement nutritionbar obtained in the last has rich nutrition and an unique saline taste flavor, and the saline taste meal replacement nutrition bar is easy to accept as daily meal replacement food by the diabetic.