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25 results about "Lactose intolerance" patented technology

An inability to digest lactose, a type sugar found in milk.

Bifidobacterium longum B14 with efficient lactose degradation capability and low gas production characteristic and application of bifidobacterium longum B14

The invention discloses bifidobacterium longum B14 with efficient lactose degradation capability and low gas production characteristic and application of the bifidobacterium longum B14, and belongs to the technical field of microorganisms. The preservation number of the bifidobacterium longum B14 is GDMCC No: 67276. The bifidobacterium longum B14 strain provided by the invention can effectively decompose lactose in intestinal tracts, meanwhile, uncomfortable symptoms such as abdominal distension caused by gas production are reduced to the maximum extent, and the technical problem that in the prior art, an efficient lactose degradation strain and the low gas production characteristic are difficult to consider at the same time is successfully solved. The invention provides a core strain resource for developing probiotic products capable of relieving main symptoms of lactose intolerance and remarkably reducing side effects. The strain has a definite application prospect and a remarkable industrial value in development of health care products and medicines.
Owner:GUANGZHOU QINCHUANGYUAN BIOTECHNOLOGY CO LTD

Zero-lactose milk containing galactooligosaccharide and preparation method thereof

The invention discloses zero-lactose milk containing galactooligosaccharide and a preparation method of the zero-lactose milk, and belongs to the technical field of dairy products. By means of the synergistic effect of the immobilized lactase and the acerola cherry powder extract, efficient hydrolysis of lactose is achieved, the lactose content is reduced to 0.1-0.5 g / 100 mL, meanwhile, 1.0-2.5 g / 100 mL of galactooligosaccharide is generated, and the lactase is especially suitable for people with lactose intolerance to drink. The preparation method comprises the following steps: pasteurizing the raw milk at 60-65 DEG C for 20-40 minutes, and then cooling; adding 0.01 to 0.3 percent of immobilized lactase and 0.001 to 0.1 percent of acerola cherry powder extract under the condition of 20 to 50 DEG C, and stirring and reacting for 10 to 60 minutes; then heating at the temperature of 80-120 DEG C for 5-20 minutes for enzyme deactivation; performing ultrasonic homogenization (200 to 500W, 20 to 70kHz, 10min), cooling and filling; and finally, carrying out ultrahigh pressure sterilization for 5 minutes at 500 MPa and 28 DEG C to ensure that the product is sterile. The stability and the repeated utilization rate of the enzyme are improved through the immobilized enzyme technology, and due to the addition of the acerola cherry powder extract, the product is endowed with natural oxidation resistance while the lactose is synergistically hydrolyzed.
Owner:CHANG CHUN SHI GUANG YUAN MU YE YOU XIAN GONG SI

Fermented milk product for administration in canids such as dogs, and uses thereof

ActiveUS12582681B2BacteriaDigestive systemBiotechnologyLactose intolerance
Fermented milk products can provide multiple benefits. However, it was commonly believed that fermented milk products are not suitable for the administration to canids as e.g. dogs can be intolerant to lactose. The present invention provides fermented milk products for administration to canids.
Owner:AQUILON CYL SL

Protein powder for promoting defecation

This invention relates to the field of food technology, and in particular to a protein powder that promotes bowel movements. To address the problems of some protein powders with added dietary fiber, such as poor compatibility between dietary fiber and protein, poor solubility, rough texture, and insignificant bowel improvement effects, ultimately leading to constipation, this invention comprises whey protein powder, casein powder, inulin, fructooligosaccharides, psyllium husk powder, soybean lecithin, and β-mannanase. This protein powder offers dual benefits of protein supplementation and intestinal health regulation. It efficiently supplements the protein needed by the human body, improves protein absorption and utilization, and is suitable for individuals with lactose intolerance and weak intestinal function. Simultaneously, through the synergistic effect of prebiotics, dietary fiber, and enzymes, it gently improves constipation symptoms, regulates intestinal flora balance, enhances intestinal peristalsis, and fundamentally protects intestinal health.
Owner:SHANGHAI JIAONA BIOMEDICAL TECHNOLOGY CO LTD

A high-protein satiety rice-pea protein-containing meal replacement powder and a preparation method thereof

PendingCN122439890ABiotechnologyNutrition
The present application relates to the technical field of meal replacement powder, and discloses a high-protein satiety meal replacement powder containing rice and pea protein and a preparation method thereof.The meal replacement powder comprises a protein component, dietary fiber, high-quality oil, a sweetener, trace nutrients, a stabilizer and a flavor component; wherein the protein component is a composite protein powder prepared by homogenizing, high-temperature shearing and spray drying of rice protein and pea protein.The present application utilizes the complementary characteristics of amino acids of rice protein and pea protein to achieve balanced nutrition, low allergenicity and easy digestion; the combination of dietary fiber, high-quality oil and composite trace nutrients takes into account high protein, high satiety and comprehensive nutrition; the product is prepared by a segmented mixing process and has good stability, diverse flavors and convenient preparation, and is suitable for people with lactose intolerance, weight control, exercise and other groups, solving the technical problems of low protein content, high allergenicity, nutritional imbalance and strong beany odor of traditional meal replacement powder, and being suitable for industrialized popularization and application.
Owner:ANHUI SHUNXIN SHENGYUAN BIOLOGICAL FOOD CO LTD

Compositions for hypervesiculating gut microbes and therapeutic enzyme delivery and methods of use thereof

Engineered Bacteroides thetaiotaomicron (Bt) strains, including deletion mutant strains, and methods of use thereof are provided. Methods of delivering a therapeutic compound to a gut microbiome of a subject include generating an engineered Bacteroides thetaiotaomicron (Bt) strain to overproduce outer membrane vesicles (OMVs); loading a target therapeutic compound into the OMVs; and colonizing the gut microbiome of the subject with the engineered Bt strain. In some embodiments, the subject has at least one of lactose intolerance, phenylketonuria, inflammatory bowel disease, and a chronic intestinal condition.
Owner:WASHINGTON UNIV IN SAINT LOUIS

Aseptic high pressure high speed rotation cuts goat milk into small molecule process

This invention discloses a sterile, high-pressure, high-speed rotary process for breaking down goat milk into smaller molecules, belonging to the field of food processing technology. The process includes the following steps: after pretreatment, pasteurization, and homogenization, the goat milk undergoes ultra-high pressure homogenization. A homogenizing valve cutting component passes through the milk at high pressure and high flow rate, breaking down large molecules into smaller molecules. Hydrophobically modified xanthan gum-gellan gum-chitosan composite lactase microcapsules are prepared and added to the small-molecule goat milk at a mass ratio of 4‰-6‰ for enzymatic hydrolysis. The mixture is then filtered to obtain sterile, low-lactose, small-molecule goat milk. Ultra-high pressure homogenization achieves the downsizing of goat milk, improving its digestibility and absorption. The composite microcapsule encapsulation of lactase enables efficient lactose hydrolysis. Hydrophobic modification of xanthan gum enhances the encapsulation efficiency and operational stability of the microcapsules. This invention provides a continuous and sterile process, ensuring adequate aseptic protection. The resulting product combines easy absorption due to its small molecular size with low lactose content, making it suitable for lactose-intolerant individuals and those with weak digestive systems.
Owner:SHAANXI BOLING DAIRY CO LTD

A loratadine immediate-release tablet based on co-micronization technology and a preparation method thereof

ActiveCN120859954BLactose intolerancePharmacy medicine
The application relates to the technical field of pharmaceutical preparations, in particular to a loratadine immediate-release tablet based on a co-micronization technology and a preparation method thereof; a pharmaceutical composition comprises a co-micronization compound, the co-micronization compound comprises loratadine and a co-micronization carrier; the application discloses a loratadine immediate-release tablet based on a co-micronization technology and a preparation method thereof, the dissolution rate and stability of the loratadine are improved by adopting the co-micronization technology and a new type of excipient combination; meanwhile, the prepared loratadine immediate-release tablet also has good in-vitro dissolution performance; the loratadine immediate-release tablet prepared by the application reduces impurity growth in the production and storage processes and obviously improves the stability of the drug; the loratadine immediate-release tablet disclosed by the application does not contain lactose in the prescription, so that the side reaction of lactose intolerance can be effectively avoided.
Owner:JIANGSU YABANG AIPUSEN PHARMA

A process for the manufacture of a freeze-dried baby cheese

The present application belongs to the technical field of cheese preparation, and particularly relates to a method for preparing freeze-dried infant cheese, which comprises primary ingredient preparation, secondary ingredient preparation, cheese shaping, freeze-drying technology and demolding. The required substances for the primary ingredient preparation include fresh milk, edible bacterial strains and rennet. The required substances for the secondary ingredient preparation include prepared fresh cheese, fruits, trehalose, full-fat milk powder, fructo-oligosaccharides, starch, DHA and nutrients. The present application obtains infant cheese which is rich in edible bacterial strains, high in nutritional ingredients, can convert most of the lactose into lactic acid, reduces the problem of lactose intolerance after the infant consumes the cheese, and meets the eating needs of the infant. Meanwhile, the present application not only enriches the types and hierarchical levels of the taste of the cheese, locks the nutritional ingredients in the cheese product, ensures that the cheese product has good nutritional value, but also guarantees the comprehensiveness and balance of the nutritional substances obtained by the infant after consuming the cheese, ensures the absorption effect, and is suitable for large-scale promotion.
Owner:RIZHAO CHANGRONG BIOTECHNOLOGY CO LTD

High content soluble protein and gamma-aminobutyric acid quinoa milk and a preparation method thereof

The application discloses high-content soluble protein and gamma-aminobutyric acid quinoa milk and a preparation method thereof, and belongs to the technical field of plant milk. The preparation method of the quinoa milk is as follows: quinoa seeds are subjected to cold plasma treatment, and then subjected to germination treatment to obtain germinated quinoa; the germinated quinoa is dried and crushed to obtain germinated quinoa powder; Bacillus subtilis fermentation liquor is added to the germinated quinoa powder for fermentation to obtain quinoa powder fermentation liquor; the quinoa powder fermentation liquor is dried to obtain fermented quinoa powder; then water is added and uniformly mixed to obtain quinoa mixed slurry. The quinoa mixed slurry is subjected to enzymolysis to obtain an enzymolysis liquor; coconut oil and a stabilizer are added to the enzymolysis liquor, and high-pressure microjet treatment is performed to obtain the quinoa milk. The prepared quinoa milk has high contents of soluble protein and gamma-aminobutyric acid, can be used as a milk substitute, and can solve the problems of lactose intolerance and unbalanced nutrition of plant milk, so that the quinoa milk has a good application prospect and value in the technical field of plant milk.
Owner:ZHEJIANG UNIV OF TECH +1

Detection reagent and detection kit for lactose intolerance judgment and qualitative judgment method for lactose content in excrement sample

The invention discloses a detection reagent and a detection kit for lactose intolerance judgment and a qualitative judgment method for the lactose content in an excrement sample. The detection reagent is used for detecting an excrement sample to judge whether the excrement sample is a lactose-intolerant sample or not, comprises organic dye and strong-alkali weak-acid salt, presents different colors before and after reacting with lactose, and judges whether the excrement sample is the lactose-intolerant sample or not by reacting the excrement sample with the detection reagent. The detection reagent provided by the invention can be used for directly qualitatively detecting the content of reducing sugar in an excrement sample extracting solution according to different colors presented by a reaction system before and after the reaction of organic dye and lactose, so that whether a sample is a lactose intolerant sample or not can be quickly judged; meanwhile, heavy metal ions and the like are prevented from being used, the experiment safety is improved, and the method is friendly to experimenters.
Owner:XINFU MEDICAL TECHNOLOGY (HANGZHOU) CO LTD

Preparation of water-soluble uniform heteropolysaccharides from highland barley and its new application in promoting expression of small intestinal mucosa β-galactosidase

PendingCN122277761ALactose intoleranceWater soluble
This invention discloses a method for preparing a water-soluble homogeneous heteropolysaccharide from highland barley and its novel application in promoting the expression of β-galactosidase in the small intestinal mucosa, belonging to the field of polysaccharide preparation and application technology. This invention provides a method for preparing the water-soluble homogeneous heteropolysaccharide HBP-1a from highland barley, involving extraction, alcohol precipitation, decolorization, and deproteinization of highland barley raw materials, followed by separation and purification using anion exchange column chromatography and gel column chromatography. The water-soluble homogeneous heteropolysaccharide HBP-1a was successfully isolated from the highland barley polysaccharide. This invention is the first to discover that the water-soluble homogeneous heteropolysaccharide HBP-1a can effectively promote the expression of β-galactosidase in the small intestinal mucosa and can be used to improve symptoms related to lactose intolerance diarrhea. This invention explores a new use for the water-soluble homogeneous heteropolysaccharide HBP-1a from highland barley, broadening its application fields and possessing broad prospects and market value.
Owner:HUBEI UNIV OF TECH

Animal and plant peptide-containing formula food suitable for inflammatory bowel disease and preparation method of animal and plant peptide-containing formula food

The invention belongs to the technical field of formula food for special medical purposes, and particularly discloses animal and plant peptide-containing formula food suitable for inflammatory bowel diseases and a preparation method of the animal and plant peptide-containing formula food. The nutritional food has the advantages of good flowability and solubility, good nutrient uniformity, high quality, no residue feeling, easy absorption, high safety and the like, and meets the requirements of patients with inflammatory enteritis on nutritional food. The composition has the following specific effects: (1) the composition has a recovery effect on intestinal tracts of mice with enteritis; and (2) the low-FODMAP dietary fiber has the effect of improving intestinal inflammation of enteritis patients. (3) the lactose content is extremely low, so that the milk powder is suitable for people with lactose intolerance to eat, and (4) the milk powder has the effects of regulating the pH value of intestinal tracts of mice and proliferating probiotics.
Owner:HUNAN SUNMYAN FSMP BIO-TECH CO LTD

Lactobacillus plantarum with the function of relieving antibiotic diarrhea and lactose intolerance, complex probiotic and application thereof

PendingCN122628950ABiotechnologyAntibiotic-associated diarrhoea
The present application discloses a plant lactobacillus, a complex probiotic for relieving antibiotic diarrhea and lactose intolerance, and an application. The plant lactobacillus MEMP0029 has been preserved in the China General Microbiological Culture Collection Center on January 8, 2026, and the preservation number is CGMCC No. 37324. The present application obtains a complex probiotic by compounding the plant lactobacillus, lactobacillus rhamnosus and lactobacillus reuteri. The plant lactobacillus MEMP0029 has high lactase production characteristics and excellent probiotic function, can effectively relieve antibiotic associated diarrhea and lactose intolerance diarrhea through multiple pathways such as regulating intestinal flora, repairing intestinal barrier, improving lactase activity and inhibiting intestinal inflammation, and has extremely high development and application value.
Owner:TIANJIN UNIV OF SCI & TECH

Kluyveromyces marxianus strain, microbial agent, fermentation broth, fermented food, and preparation and use thereof

PCT designated stageWO2025256505A1FungiMilk preparationBiotechnologyLactose intolerance
The present invention belongs to the field of fermentation, and specifically relates to a Kluyveromyces marxianus strain, a microbial agent, a fermentation broth, a fermented food, and a preparation and a use thereof. Provided is Kluyveromyces marxianus AMCC 31586, having the accession number CCTCC NO:M20231793. In one aspect, Kluyveromyces marxianus AMCC 31586 has good substrate utilization ability, being able to fully utilize carbon source substrates such as lactose and galactose, thereby reducing the health burden of people with lactose intolerance or galactosemia. In another aspect, fermented milk obtained by fermentation with Kluyveromyces marxianus AMCC 31586 contains unique flavor substances such as eugenol and anethole, and it also has good utilization ability for carbon source substrates such as organic acids, lactose and galactose. Furthermore, in dairy fermentation, it can improve the quality of fermented dairy products and enrich the flavor of fermented dairy products.
Owner:ANGEL YEAST CO LTD

Lutein-wolfberry probiotic yoghourt as well as preparation method and application thereof

PendingCN121986847AMilk preparationFrozen sweetsBiotechnologyProbiotic yogurt
The invention provides lutein Chinese wolfberry probiotic yoghurt and a preparation method and application thereof, and relates to the technical field of yoghurt, the lutein Chinese wolfberry probiotic yoghurt is prepared from the following raw materials in percentage by mass: 2-10% of Chinese wolfberry, 0.1-0.9% of lutein, 2-10% of white sugar, 0.02-0.06% of a leavening agent and the balance of fresh milk, the lutein provides a growth-promoting microenvironment for probiotics and enhances the probiotic function expression of the probiotics; meanwhile, xanthophyll and lycium barbarum polysaccharide form a synergistic interaction mechanism, the water-holding capacity and physical stability of the product are remarkably improved, on the other hand, by optimizing the proportion of lycium barbarum and white granulated sugar, proliferation of lactic acid bacteria in the fermentation period is promoted, the stability in the storage period is prolonged, lactose intolerance symptoms are relieved in an auxiliary mode, and the intestinal microecological regulation function is strengthened; the flavor and texture characteristics of the product are improved; the lutein Chinese wolfberry probiotic yoghourt can promote tear secretion, protect cornea and influence the expression of IL-6, TNF-alpha and IL-1beta in cornea tissues.
Owner:NINGXIA UNIVERSITY

A stacked kit for detecting human lactose intolerance genes

ActiveCN224428383ULactose intoleranceBiomedical engineering
This utility model relates to the field of reagent kit technology and discloses a stackable reagent kit for detecting human lactose intolerance genes. The kit includes a first reagent kit, with a second reagent kit placed on top of the first kit. A plug is inserted into a socket, aligning the positioning posts with the positioning holes. The spring's restoring force pushes the two sets of positioning posts to slide and reset within guide grooves, allowing them to pass through the two sets of positioning holes. This achieves the purpose of stacking and connecting multiple reagent kits, facilitating the handling of multiple kits by medical personnel and preventing the kits from sliding and falling during transport, which could lead to reagent bottle leakage, environmental pollution, or even endanger the health and safety of testing personnel.
Owner:GUIZHOU KANGYUAN BIOTECHNOLOGY CO LTD

A zero-lactose low-protein formula goat milk powder for animals and a preparation method thereof

PendingCN122623760ABiotechnologyLactase
The present application relates to the field of animal nutrition and feed processing technology, and more particularly to a zero-lactose low-protein formula goat milk powder for animals and a preparation method thereof, the raw materials of the goat milk powder are fresh goat milk, compound enzymes and vitamins; the compound enzymes are composed of neutral lactase, compound protease and flavor enzyme at a mass ratio of 0.6-3:0.02-0.1:0.5-2.5. The present application successfully prepares a zero-lactose low-protein formula goat milk powder for animals with a lactose content of less than 0.22%, a protein content of about 12.5%, excellent fluidity and high stability in brewing by low-temperature long-time enzymolysis, synergistic effect of compound protease and flavor enzyme, embedding protection of flavor enzyme and microencapsulation of fat-soluble vitamins, eliminates the risk of lactose intolerance, reduces the protein allergenicity, optimizes the nutrient absorption and balance, and provides a more scientific feeding solution for sensitive or special-demand animals.
Owner:HENAN ANJIN BIOENGINEERING CO LTD

Preparation method of low-lactose fermented cream cheese suitable for people with lactose intolerance

The invention relates to the technical field of food processing, in particular to a preparation method of low-lactose fermented cream cheese suitable for people with lactose intolerance. Through the key steps of stabilizer pretreatment, sectional beta-galactoside enzymolysis, compound leavening agent acid-controlled fermentation, low-temperature centrifugation, homogenizing redissolution and the like, the lactose residue is further reduced, and meanwhile, the excellent texture and flavor are kept. The method does not need ultrafiltration equipment, the enzyme can be recycled, the method is suitable for industrial production, the contradiction between incomplete lactose removal and texture deterioration in the prior art is solved, and the method has remarkable economic benefits and social values.
Owner:Shanghai Kechuang Vocational and Technical College

Preparation method of strontium-enriched lactobacillus plantarum powder

PendingCN121950574Aclear rationalityClarify feasibilityBacteriaMicroorganism based processesBiotechnologyNatural source
The invention discloses a preparation method of strontium-enriched lactobacillus plantarum powder, and relates to a preparation method of probiotic powder. The invention aims to solve the problems that at present, people can only supplement strontium through drinking water and cannot realize continuous intake by combining with daily diet, and free strontium is relatively low in absorption rate in human intestinal tracts and difficult to meet nutritional requirements. The method comprises the following steps: 1, preparing a strontium-rich culture medium; 2, fermenting the lactobacillus plantarum; and 3, preparing bacterial powder. The strontium-rich lactobacillus plantarum developed by the invention has definite market rationality and technical feasibility, lactobacillus plantarum can be protected from oxidative damage in the processing and intestinal transfer processes, and the survival rate of viable bacteria is improved; in addition, the bone protection function of strontium and the bone protection function of strontium are complementary; the strontium-enriched lactobacillus plantarum powder prepared by the method has the psychological expectations of'natural sources' and'no additive burden ', can be used as a daily diet supplement, can also be adapted to subdivided scenes such as mothers and infants, fitness and health care, and is adapted to special crowds with lactose intolerance and the like.
Owner:HEILONGJIANG ACAD OF SCI INST OF NATURAL RESOURCES

Lactose intolerance test bottle

ActiveCN310132266SLactose intoleranceBiomedical engineering
1. Name of the product in this design: Lactose Intolerance Test Bottle. 2. Purpose of this design: This design is used to detect lactose intolerance indicators. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.
Owner:COFOE MEDICAL TECH CO LTD

Millet yoghourt and preparation method thereof

The invention relates to the technical field of fermented dairy product processing, in particular to millet yoghourt and a preparation method thereof. The preparation method of the millet yoghourt comprises the following steps: crushing millet, adding the crushed millet into water, and boiling to obtain millet slurry; adding white granulated sugar and millet pulp into pure milk, uniformly mixing, then sterilizing at a high temperature, cooling to a fermentation temperature, inoculating a composite leavening agent, uniformly mixing, fermenting for 4.5 hours, refrigerating and ripening to obtain the millet yoghourt, the addition amount of the millet is 12% of the mass of the pure milk; the addition amount of the white granulated sugar is 9% of the mass of the pure milk. According to the invention, the problems of rough taste, inharmonious flavor and insufficient nutrient enrichment of the traditional grain yoghurt are solved, and the functional millet yoghurt product which has the fragrance of millet grains and the sour and sweet taste of yoghurt and meets the national standard is obtained. The yoghurt product is high in nutrition complementarity, stable in process and suitable for people with lactose intolerance, high blood sugar and weakness of the spleen and the stomach, and has a good industrial application prospect.
Owner:SHANXI AGRI UNIV

Kluyveromyces marxianus strain, fungicide, fermentation liquor, fermented food and preparation and application of kluyveromyces marxianus strain

The invention belongs to the field of fermentation, and particularly relates to a kluyveromyces marxianus strain, a microbial inoculum, a fermentation broth, a fermented food, and preparation and application of the kluyveromyces marxianus strain. The invention provides Kluyveromyces marxianus AMCC 31586 (Kluyveromyces marxianus AMCC 31586), and the preservation number of the Kluyveromyces marxianus AMCC 31586 is CCTCC (China Center For Type Culture Collection) CNO (China Center For Type Culture Collection): M 20231793. On one hand, the kluyveromyces marxianus AMCC 31586 has good substrate utilization capacity, carbon source substrates such as lactose and galactose can be fully utilized, the health burden of people suffering from lactose intolerance or galactosemia is reduced, on the other hand, the fermented milk obtained by fermenting the kluyveromyces marxianus AMCC 31586 contains unique flavor substances such as eugenol and anethole, and the health burden of people suffering from lactose intolerance or galactosemia is reduced. The strain has good utilization capability on carbon source substrates such as organic acids, lactose and galactose, and can improve the quality of fermented dairy products and enrich the flavor of the fermented dairy products in the fermentation of the dairy products.
Owner:ANGEL YEAST CO LTD

Probiotics with weight-losing effect and preparation method thereof

The invention relates to the technical field of probiotics, particularly discloses a probiotic with a weight-losing effect, and aims to provide the probiotic with the weight-losing effect. The probiotic composition is prepared from probiotics, the probiotics are metered according to a single dose of 1.5 g, and the other components comprise the following components in percentage by weight of the single dose: 7%-12% of functional probiotic strains, 18%-25% of xylooligosaccharide, 5%-10% of a gastric acid protective agent, 30%-40% of hydroxyethyl cellulose, 20%-25% of low-methoxyl pectin and 1%-5% of an anti-caking agent. Meanwhile, the probiotic composition is suitable for most people with lactose intolerance, the stability and the weight-losing effect of the probiotic composition are improved, the weight-losing effect is remarkable, and the suitable people range is wide.
Owner:QINGDAO KANGYI BIOTECHNOLOGY CO LTD