The invention discloses an
ebastine oral solution preparation method, which comprises: 1, weighing 5-20 parts by
mass of
ebastine, 50-100 parts by
mass of a
thickening agent, 10-18 parts by
mass of a
bacteriostatic agent, 1800-2000 parts by mass of a
thickening agent, 0.1-0.2 part by mass of a defoaming agent, 600-700 parts by mass of a
sweetening agent, adjusting the pH value to 3.5-4.5 by using a pH value adjusting agent, and carrying out a proper amount of water; 2, adjusting the temperature to 35 DEG C, adding
ebastine into the
thickening agent, and stirring to completely disperse the ebastine; 3, adding part of
purified water, an
acidity regulator and a thickening agent, and stirring until the materials are completely dissolved; 4, adding the
sweetening agent, the
bacteriostatic agent and the defoaming agent, and stirring until the materials are completely dissolved; 5, cooling after complete
dissolution, and adjusting the pH value to 4 by using an alkaline
regulator; step 6, fixing the volume; by optimizing the preparation process, efficient
dissolution of the ebastine oral solution is realized, the problems of clinical application pain points of tablets and low
solubility of
raw material medicines of the oral solution are solved, and a
safer and more convenient treatment choice is provided for special
crowds.