The invention belongs to the technical field of hydrogel adhesives, and relates to a Janus hydrogel
adhesive and a preparation method thereof. The preparation method comprises the following steps: dissolving a
monomer with a coordination group, a surfactant, a cross-linking agent, a thermal initiator, a pH
regulator and a natural
polymer with a strong adhesion site in water, and carrying out one-step thermal
initiation polymerization in a manner of covering a hydrogel pre-solution with a specific
metal plate to prepare the Janus hydrogel
adhesive. An in-situ cross-linking reaction / coordination effect occurs at a
metal interface, so that one side of a covering
metal plate in the hydrogel achieves an anti-adhesion effect; through the synergistic effect of bonding sites such as a coordination group, a hydroxyl group and an amino group, the strong adhesion effect of one side, which is not covered with a metal plate, in hydrogel is achieved, so that the Janus hydrogel
adhesive with asymmetric adhesion is obtained. The method is suitable for preparing asymmetric adhesive gel and postoperative anti-adhesion materials, is used in the fields of intelligent sensors, flexible electronic devices, ultrasonic couplants and the like, is simple and convenient in preparation process, low in cost and easy for large-scale production, and has potential application value.